Can I use
?

HTTP Live Streaming (HLS)

- UNOFF

HTTP-based media streaming communications protocol

Chrome

  1. ❌ 4 - 141: Not supported
  2. ✅ 142: Supported
  3. ✅ 143: Supported
  4. ✅ 144 - 146: Supported

Edge

  1. ✅ 12 - 18: Supported
  2. ❌ 79 - 142: Not supported
  3. ❌ 143: Not supported

Safari

  1. ❌ 3.1 - 5.1: Not supported
  2. ✅ 6 - 26.1: Supported
  3. ✅ 26.2: Supported
  4. ✅ 26.3 - TP: Supported

Firefox

  1. ❌ 2 - 145: Not supported
  2. ❌ 146: Not supported
  3. ❌ 147 - 149: Not supported

Opera

  1. ❌ 9 - 124: Not supported
  2. ❌ 125: Not supported

IE

  1. ❌ 5.5 - 10: Not supported
  2. ❌ 11: Not supported

Chrome for Android

  1. ✅ 143: Supported

Safari on iOS

  1. ✅ 3.2 - 26.1: Supported
  2. ✅ 26.2: Supported
  3. ✅ 26.3: Supported

Samsung Internet

  1. ✅ 4 - 28: Supported
  2. ✅ 29: Supported

Opera Mini

  1. ❌ all: Not supported

Opera Mobile

  1. ❌ 10 - 12.1: Not supported
  2. ✅ 80: Supported

UC Browser for Android

  1. ✅ 15.5: Supported

Android Browser

  1. ❌ 2.1 - 2.3: Not supported
  2. ✅ 3 - 4.4.4: Supported
  3. ✅ 143: Supported

Firefox for Android

  1. ✅ 146: Supported

QQ Browser

  1. ✅ 14.9: Supported

Baidu Browser

  1. ✅ 13.52: Supported

KaiOS Browser

  1. ❌ 2.5: Not supported
  2. ❌ 3: Not supported

HLS can be used with a JavaScript library in browsers that doesn't support it natively as long as they support Media Source Extensions.

Resources:
Apple developer article
Wikipedia article