Package: DominoEffect Type: Package Title: Identification and Annotation of Protein Hotspot Residues Version: 1.29.0 Author: Marija Buljan and Peter Blattmann Maintainer: Marija Buljan <[email protected]>, Peter Blattmann <[email protected]> Description: The functions support identification and annotation of hotspot residues in proteins. These are individual amino acids that accumulate mutations at a much higher rate than their surrounding regions. License: GPL (>= 3) Encoding: UTF-8 LazyData: true Depends: R(>= 3.5) Imports: biomaRt, data.table, utils, stats, Biostrings, pwalign, SummarizedExperiment, VariantAnnotation, AnnotationDbi, GenomeInfoDb, IRanges, GenomicRanges, methods Suggests: knitr, testthat, rmarkdown RoxygenNote: 6.0.1 VignetteBuilder: knitr biocViews: Software, SomaticMutation, Proteomics, SequenceMatching, Alignment NeedsCompilation: no