@@ -547,8 +547,8 @@ getMITScores(spacers=spacer,

 ```

     ##                 spacer          protospacer      score

-    ## 1 ATCGATGCTGATGCTAGATA ACCGATGCTGATGCTAGATA 0.68500000

-    ## 2 ATCGATGCTGATGCTAGATA ATCGATGCTGATGCTAGATT 0.00000000

+    ## 1 ATCGATGCTGATGCTAGATA ACCGATGCTGATGCTAGATA 0.31500000

+    ## 2 ATCGATGCTGATGCTAGATA ATCGATGCTGATGCTAGATT 1.00000000

     ## 3 ATCGATGCTGATGCTAGATA ATCGATGCTGATGCTAGATA 0.06944444

 ## CFD score

@@ -651,7 +651,7 @@ sessionInfo()

     ## [1] stats     graphics  grDevices utils     datasets  methods   base     

     ## 

     ## other attached packages:

-    ## [1] crisprScore_1.1.15    crisprScoreData_1.1.3 ExperimentHub_2.5.0  

+    ## [1] crisprScore_1.3.2     crisprScoreData_1.3.0 ExperimentHub_2.5.0  

     ## [4] AnnotationHub_3.5.1   BiocFileCache_2.5.0   dbplyr_2.2.1         

     ## [7] BiocGenerics_0.43.4  

     ## 

@@ -665,10 +665,10 @@ sessionInfo()

     ## [13] RSQLite_2.2.16                evaluate_0.16                

     ## [15] highr_0.9                     httr_1.4.4                   

     ## [17] pillar_1.8.1                  basilisk_1.9.6               

-    ## [19] zlibbioc_1.43.0               rlang_1.0.5                  

+    ## [19] zlibbioc_1.43.0               rlang_1.0.6                  

     ## [21] curl_4.3.2                    rstudioapi_0.14              

     ## [23] blob_1.2.3                    S4Vectors_0.35.3             

-    ## [25] Matrix_1.4-1                  reticulate_1.26              

+    ## [25] Matrix_1.5-3                  reticulate_1.26              

     ## [27] rmarkdown_2.16                stringr_1.4.1                

     ## [29] RCurl_1.98-1.8                bit_4.0.4                    

     ## [31] shiny_1.7.2                   compiler_4.2.1               

@@ -682,13 +682,13 @@ sessionInfo()

     ## [47] later_1.3.0                   basilisk.utils_1.9.3         

     ## [49] bitops_1.0-7                  rappdirs_0.3.3               

     ## [51] grid_4.2.1                    jsonlite_1.8.0               

-    ## [53] xtable_1.8-4                  lifecycle_1.0.1              

+    ## [53] xtable_1.8-4                  lifecycle_1.0.3              

     ## [55] DBI_1.1.3                     magrittr_2.0.3               

     ## [57] cli_3.4.0                     stringi_1.7.8                

     ## [59] cachem_1.0.6                  XVector_0.37.1               

     ## [61] promises_1.2.0.1              ellipsis_0.3.2               

     ## [63] filelock_1.0.2                generics_0.1.3               

-    ## [65] vctrs_0.4.1                   tools_4.2.1                  

+    ## [65] vctrs_0.5.1                   tools_4.2.1                  

     ## [67] bit64_4.0.5                   Biobase_2.57.1               

     ## [69] glue_1.6.2                    purrr_0.3.4                  

     ## [71] BiocVersion_3.16.0            parallel_4.2.1