في علم الأوبئة، يمثل رقم التكاثر الأساسي عدد الحالات التي تُنتجها حالة واحدة مُصابة خلال فترة العدوى بين مجموعة غير مُصابة،. وبصفة عامة، إذا كان رقم التكاثر أقل من (1)، فإن فرصة العدوى ستتضاءل حتى يختفي المرض تمامًا، أما إن كان أكبر من (1)، فإن كل شخص مُصاب سوف ينقل العدوى إلى شخصٍ آخر على الأقل، مع الوضع في الاعتبار عدم تجانس المجتمعات من حيث نمط الحياة. وتتراوح التقديرات الحالية لعدد التكاثر الأساسي لفيروس كورونا المستجد (أو كوفيد-19) بين 2 و3، (...) ليقترب بهذا من عدد التكاثر الأساسي لفيروس «سارس»، الذي تراوح بين 2 و4 في سنة 2003. (shrink)

This paper presents a comprehensive analysis of the SEIRS COVID-19 pandemic model with saturated incidence rate. By modifying the existing model and proposing a new simplified version, we investigate the dynamics of disease transmission, including the impact of saturation terms on disease spread. Through stability analysis at disease-free and endemic equilibria, we aim to enhance understanding of the spread of COVID-19 and inform effective control strategies. Drawing on mathematical models and epidemiological insights, this study contributes to the ongoing efforts to (...) combat the global pandemic. (shrink)

I Was Born Not by My Decision, but by My Parents’ Decision -/- Life begins not as a result of our own choices, but as a consequence of the decisions made by our parents. From the moment of conception, the circumstances of our birth are determined by factors beyond our control—our parents’ choices, their social and economic status, and the country in which we are born. This reality shapes the foundation of our lives and presents us with both opportunities and (...) challenges that we must navigate as we grow. -/- The Decision of My Parents -/- Before I existed, my parents made the decision to bring a child into the world. Whether planned or unplanned, their choices set the stage for my existence. I had no say in being born, nor in selecting the family that would raise me. My parents’ values, beliefs, and resources directly influenced the environment in which I was raised. For example, a child born into a family of doctors may be encouraged to pursue a career in medicine, while a child raised in a family struggling with financial instability may be forced to take on responsibilities at a young age to help support the household. Some parents provide a nurturing and supportive home, while others may struggle with challenges such as addiction, mental illness, or financial stress that affect their ability to care for their children properly. -/- The Country of My Birth: Poor or Rich -/- Another aspect beyond my control is the country in which I was born. Some are born into wealthy nations with stable economies, advanced healthcare, and numerous opportunities for education and personal growth. For instance, a child born in Switzerland, which has one of the highest standards of living in the world, may have access to world-class education and healthcare. In contrast, a child born in a war-torn or impoverished nation, such as Afghanistan or the Democratic Republic of Congo, may face malnutrition, lack of access to education, and a higher risk of disease. The economic status of a country affects not only an individual’s quality of life but also their ability to pursue their aspirations. However, history has shown that determination and resilience can help individuals rise above their circumstances, such as Malala Yousafzai, who, despite being born in Pakistan where girls’ education was under threat, fought for her right to learn and became a global advocate for education. -/- Good or Bad Parents -/- Parents play a crucial role in shaping a child’s future. Some are loving, responsible, and dedicated to their children’s well-being, while others may be neglectful, abusive, or absent. A good parent provides guidance, love, and support, helping a child develop confidence and a sense of security. For example, Barack Obama was raised by a single mother who emphasized the importance of education and hard work, which greatly influenced his path to becoming the President of the United States. On the other hand, children who grow up in abusive households, such as those with alcoholic or violent parents, may struggle with emotional and psychological challenges that affect their future relationships and career paths. While a child’s upbringing has a significant impact on their life, it does not define their entire destiny. Many individuals have overcome difficult childhoods and gone on to achieve great things, proving that while parental influence is strong, personal determination can be stronger. A well-known example is Oprah Winfrey, who grew up in poverty and faced many hardships but persevered to become one of the most influential media personalities in the world. -/- The Role of Government in Solving the Street Children Crisis -/- While family and economic conditions influence a child’s future, the government plays a crucial role in addressing social issues like the crisis of street children. Many children end up homeless due to poverty, neglect, abuse, or lack of access to education and healthcare. Governments must implement policies and programs to ensure that all children have the opportunity to grow in a safe and nurturing environment. -/- For instance, countries like Finland and Norway have successfully reduced child homelessness through social welfare programs that provide housing, education, and healthcare for underprivileged children. Governments can establish shelters, provide free education, and create job opportunities for struggling families to prevent children from ending up on the streets. Additionally, strong child protection laws and social services can intervene in cases of abuse and neglect, offering children a chance at a better future. The success of these programs in various nations proves that when governments take proactive steps, they can make a significant impact in solving societal issues like street children. -/- The Importance of Free Public Basic Educational Institutions -/- Access to free public education is one of the most powerful tools in breaking the cycle of poverty and inequality. Basic education provides children with essential knowledge and skills that enable them to contribute productively to society. Without free public schools, many children, especially those from low-income families, would have no access to quality education, limiting their future opportunities. -/- Countries with strong public education systems, such as Finland and Germany, ensure that all children receive high-quality education regardless of their socioeconomic background. Education empowers individuals to make informed decisions, pursue higher education or vocational training, and secure stable jobs. Moreover, it promotes social mobility, allowing children from poor families to improve their circumstances through learning. Governments should prioritize investment in free and accessible education, as it is a long-term solution to reducing poverty and creating a more equitable society. -/- The Importance of Planned Birth -/- Family planning plays a vital role in ensuring that children are born into environments where they can receive proper care, love, and support. Planned births allow parents to prepare financially, emotionally, and mentally for raising a child, reducing the likelihood of neglect or hardship. When parents have control over the number of children they have, they can allocate more resources to each child, improving their quality of life. -/- Unplanned pregnancies often result in financial strain, emotional stress, and instability within families. In some cases, children born into such situations may suffer from malnutrition, lack of education, or even abandonment. Governments and organizations worldwide have recognized the importance of family planning and have implemented programs to educate and provide access to contraception and reproductive health services. Countries like Thailand and Bangladesh have successfully reduced poverty rates through strong family planning policies, ensuring that families can provide adequately for their children. -/- The Importance of an Educational System in Producing High-Quality Young Parents -/- A well-structured educational system not only prepares students for careers but also equips them with essential life skills, including responsible parenting. Comprehensive education in reproductive health, emotional intelligence, and financial literacy helps young people make informed decisions before starting a family. -/- For example, the Netherlands has one of the lowest teenage pregnancy rates in the world due to its comprehensive sex education curriculum, which emphasizes responsibility, contraception, and healthy relationships. In contrast, countries with limited reproductive education often struggle with high rates of unplanned pregnancies and economic instability among young parents. -/- Education also plays a crucial role in fostering responsible parenting by teaching young people how to provide a stable and nurturing environment for their future children. Programs like parenting workshops in Scandinavian countries have shown that educated parents are more likely to raise well-adjusted children who contribute positively to society. -/- The Importance of Regulated Population Growth Rate -/- One of the most critical factors in ensuring sustainable development is the regulation of population growth. Uncontrolled population growth can lead to resource depletion, environmental degradation, and increased poverty. Overpopulation puts pressure on public services, healthcare, education, and housing, often leading to inequality and scarcity. -/- Governments play a crucial role in regulating population growth through policies and initiatives that promote family planning and responsible reproduction. Countries that have successfully implemented population control measures, such as China’s one-child policy (which has now evolved), have witnessed significant improvements in resource allocation, economic stability, and quality of life for their citizens. Other nations, such as Japan and Germany, have also addressed population imbalances through pro-natalist policies and improved healthcare access. -/- Regulating population growth is not about limiting human rights but ensuring that resources are available to meet the needs of both current and future generations. As the global population continues to grow, governments must invest in sustainable practices and encourage responsible family planning to avoid overcrowding, strained resources, and widespread poverty. Countries like Singapore and Thailand, which have prioritized family planning and reproductive health services, show how such policies can lead to healthier, more prosperous societies. -/- Conclusion -/- The circumstances of my birth—my parents’ decision, the country I was born in, and the kind of parents I had—were all beyond my control. However, what truly matters is how I respond to these circumstances. Life is not just about where we start but about the choices we make as we grow. Regardless of whether we were born into privilege or hardship, we have the ability to shape our own future. -/- Education, government policies, and personal determination play a crucial role in improving individual and societal outcomes. By investing in education, family planning, regulated population growth, and social welfare, societies can create a better future for all children, regardless of the circumstances of their birth. -/- . (shrink)

The concept of universal in Aristotle’s philosophy has several aspects. 1) Universal and plurality Aristotle posits universal (καθόλου) versus particular (καθ᾿ ἕκαστον) each covering a range of elements: some elements are universal while others are particulars. Aristotle defines universal as ‘that which by nature is predicated (κατηγορεῖσθαι) of many subjects’ and particular as ‘that which is not’ so. (OI ., I, 7, 17a38-b1) The plurality of possible subjects of universal is what Aristotle insists on. The inclusion of the notion of (...) ‘plurality’ in the definition of universal might make us expect to have ‘singularity’ in the definition of particular. So, when Aristotle says that universal is that which is naturally predicable of many subjects, we expect him to define the particular as ‘that which is predicable of one subject only.’ Nonetheless, Aristotle does not and indeed cannot define it this way. We cannot find a text in which he defines particular as such simply because particulars are not predicable of any subject unless we regard their predication of themselves a predication, which Aristotle does not, at least in a genuine sense. Thus, he defines a particular only negatively. Hence, the capability of predication of a plurality is indeed the capability of predication itself because the particular cannot be predicated of anything. A particular is that which cannot be predicated of anything (or: of anything else, if saying of a thing of itself is to be considered as predication). It is ‘numerically one’ and what of which the universal is predicated (Met., B, 999b34-1000a1). Those that cannot be predicated of anything, or particulars, are of two kinds: primary substances and individual accidents. Besides Categories we can hardly find a text where Aristotle discusses individual accidents maybe because they are of much less importance for him compared with substances. However, substances are what he mentions repeatedly so that we can confine particulars to substances. In fact, it is substance that Aristotle considers so repeatedly as what cannot be predicated. As the main particulars and individuals, substances are posited as the main things that are not universal. The closeness of the two concepts of ‘substance’ and ‘unpredicability’ is to the extent that he ignores individual accidents and makes these concepts equal and as the opposite of universal: ‘what is not predicated of a subject is said a substance (οὐσία λέγετα τὸ μὴ καθ᾿ ὑποκειμένου) but what is always said of some subject is called a universal.’ (Met., Z, 1038b15-16. cf. Met., B, 1003a7-9) Therefore, since particulars cannot be predicated of any subject and, thus, every predication is necessarily a predication of a plurality of subjects, the inclusion of ‘plurality’ in the definition of universal is either i) in the sense of ‘representation’ or it must be regarded as ii) an unnecessary addition mentioned just for clarification or iii) only for avoiding cases where something is predicated of itself. By the first we mean this: though a substance is not said of anything, it represents some one thing and there is some one thing that is that substance. A universal, on the other hand, can represent a plurality of things. There is, however, a third possibility that has no essential difference with the sense of representation. Aristotle might have ‘arbitrary predication’ in mind when he suses ‘plurality’ in the definition of universal: while a particular can be the arbitrary predicate of just one thing, a universal can be predicated, both really and arbitrarily, of many things. Whatever Aristotle’s intention was, what is important for our investigation is this: Aristotle uses the notion of plurality in the definition of universal in spite of the fact that it is not necessary. What this implies is that this notion is so important for Aristotle that albeit every predictability is a predictability of a possible plurality, he adds the notion of plurality. What makes this notion important, I believe, is that he has something like a class in mind when he defines a universal because the notion of plurality is indistinguishable from a class. 2) Universal and whole; particular and part In Aristotle, the concepts of universal and whole are so close: ‘That which is true of a whole class and is said to hold good as a whole (which implies that it is a kind of whole) is true of a whole in the sense that it contains many things by being predicated of each, and that each and all of them, e.g. man, horse, god, are one because all are living things (τὸ μὲν γὰρ καθόλου καὶ τὸ ὃλως λεγόμενον ὡς πολλὰ περιέχον τῷ κατηγορεῖσθαι καθ’ ἑκάστου καὶ ἓν ἃπαντα εἶναι ὡς ἑκαστον, ...). Phil Corkum points to Aristotle’s distinction between quantitative and integral wholes in Met., 5, 26, 1023b26-33 where a quantitative whole is called homoiomerous, as the sum of animal while an integral whole, e.g. a house, is called heteromerous. He links the notion of homoiomerous to the notion of indivisibility of individuals (in 1b6-9 and 3b10-18) and indivisibility of universals. He believes that in PrA., I, 4, 25b32-26a2 it is the transitivity of mereological containment that is discussed. 3) Universal is common between instances Universal is common (κοινόν) between all the plurality of subjects it can be predicated of because what belongs to more than one thing must be common between them. (Met., Z, 1038b10-12) In the Same way, what is common cannot be a particular and, thus, a substance. (Met., Z, 1040b23-24) An individual or substance is a ‘this’ and a ‘this’ cannot be what common indicates simply because it is here in ‘this’ and can be nowhere else while common must be common between several things. In fact, what can be indicated by a common is indeed a ‘such.’ (Met., B, 1003a7-9) 4) Universal is the same in its instances We have a universal i) in all of its instances and ii) in the same way (ταὐτὸ ἐπὶ πὰντων). (Met, Γ, 1005a9-10) While the first point is evident (otherwise how could it be their universal?), the second point might seem not only ambiguous but the cause of many problems. For Aristotle, therefore, a universal must be ‘one’ in number and not many. This numerically one universal is the very universal for all its instances. It is the same universal that is predicated on each of its instances. This sameness is not, however, a mere homonymous sameness or the sameness of a homonymous word. All these three points, namely oneness, sameness and rejection of mere homonymous sameness are asserted in Aristotle’s own words τι ἕν καὶ τὸ αὐτὸ ἐπὶ πλειόνων μη ὁμώνυμον. (PsA., A, 11, 77a8-9) This non-homonymous unity is asserted also in PsA., A, 24, 85b15-16. 5) Universal as predicate Contrary to substance that cannot be a predicate, universal is what cannot be prevented from being in the place of predicate. Therefore, Aristotle distinguishes universal from subject because while the latter must necessarily be capable of being a predicate, though it might take the position of subject as well, the latter does not necessarily have such a capability especially when it is a this because it cannot be a predicate in such a case: ‘For the subject and universal differ in being or not being a ‘this’; like man and body and soul are the subject of accidents while the accident is something like musical or white.’ (Met., Θ, 1049a27-30) This indicates that a universal is basically different from subject and although it can be posited in the place of subject, it is the position of predicate that is its position as a universal. In Metaphysics, Z, 13, Aristotle asserts that ‘no universal can be substance.’ The same is asserted in Met., I, 1053b16-17 cf. 1060b21. As James H. Lesher points out, Aristotle’s position is that ‘nothing predicated universally is a substance.’ 6) Universal in substance In Met., 10388b8-9 Aristotle says that no universal is a substance. While a universal cannot be a substance in the way essence (to ti en einai) is, it is, Aristotle asserts, ‘in’ it (ἐν τούτῳ δὲ ἐνυπάρχειν) (Met., Ζ, 1038b16-18). Aristotle’s examples are: animal in man and horse. A universal is ‘in’ the thing it is its universal. But in what sense a universal can be in a thing? It cannot be in it as ‘in a subject’, which is denied in Categories for secondary substances. If we check the senses of being in, we can find some other senses of ‘being in’ some of which are compatible with this sense of ‘being in.’ Michael J. Loux believes that contrary to his earlier works like Peri Ideaon and Organon in which the immanence of universals signals a reproduction of the platonic two worlds picture, in his later works like Physics and Metaphysics, when Aristotle tells us that universals are in particulars he means that they are ‘components of or ingredients in sensible particulars.’ In Metaphysics (Δ, 1014b3-9) Aristotle compares elements with universals and call them ‘the most universal things because elements are present either in all or in many things. 7) Logos is of universal Not only universals have logos (Met., Z, 1038b18-19) but ‘Every logos and every science is of universals and not of particulars.’ (Met., K, 1059b25-26) The reason is that they are the same: the logos of the unjiversal ‘circle’ is nothing but ‘being circle’ and the logos of the universal ‘soul’ is ‘being soul.’ (Met., Z, 1035b33-1036a2) The same is said about definition. (Met, Z, 1036a27-29) 8) Universal: in the soul Contrasting individuals, universals are in the soul (So., 3, 5, 417b22-23; cf. PsA., B, 19, 100a6-7). Aristotle also says that the form, i.e. the essence, of the artwork is in the soul. (met., Z, 1032a32-b2) Moreover, as Michael J. Loux points out, ‘the Peri Ideon tells us that we need universals to serve as the objects of noetic acts.’ 9) Universal: not beside individual In spite of the fact that demonstration creates the opinion that demonstrating is based on the existence of universals as existing among the existing things, they do not have existence besides individuals (PsA., A, 24, 85a31-35; Met, Λ, 1071a19-23). Aristotle believes that universals of a P-series (B203, 71) are not παρὰ τὰ εἴδη: 999a6ff. Also check De Anima, II, 3, 414b20-25 10) Primary or commensurate universal Aristotle distinguishes ‘πρῶτον καθόλού’ (PsA., B, 17, 99a33-35) literally meaning ‘primary universal’ but mostly, and truly, translated as commensurate universal. While a universal merely ‘μὴ ἀντιςτρέφει,’ a primary universal ‘ᾧ ἓκαςτον μὲν μὴ ἀντιςτρέφει’ (PsA., B, 17, 99a33-35). Aristotle mentions three conditions for a commensurate universal. It is an attribute that i) belongs to every instance of its subject (without exception!!!), and this belonging is ii) essentially and iii) qua that subject itself (ᾗ αύτό). (PsA., A, 4, 73b26-28) However, he insists that the second and the third conditions are indeed the same. (PsA., A, 4, 73b28-30) The first condition he paraphrases as ‘to belong to any random instance of that subject’ and the second and the third as ‘when the subject is the first thing to which it can be shown to belong.’ (PsA., A, 4, 73b32-74a3) Aristotle’s example is ‘the equality of its angles to two right angles’. This attribute is not a commensurate universal of figure due to the first condition: it cannot be demonstrated of any figure. Nonetheless, though it can be demonstrated of every isosceles because every isosceles has angles equal to two right angles, it is not a commensurate universal of isosceles due to the other conditions: it is not predicated of isosceles qua isosceles but qua triangle. These conditions seem to be like regulators: they organize everything to match to the right group. The method of finding commensurate universal is like test and error method based on elimination: you must eliminate each of the higher or lower universals and check if the attribute remains or not. The commensurate universal is that which remains in between eliminated universals. (cf. PsA., A, 5, 74a37-b4) Brad Inwoodpresents an understanding of commensurate universal that is different from what I have understood and, thus, must be checked: ‘These universals are propositions in which, for example, ‘all A are B’ is true and which are still true universal statements if converted: ‘all B are A’ is also true.’ -/- . (shrink)

Reproductive genetic technologies allow parents to decide whether their future children will have or lack certain genetic predispositions. A popular model that has been proposed for regulating access to RGTs is the ‘genetic supermarket’. In the genetic supermarket, parents are free to make decisions about which genes to select for their children with little state interference. One possible consequence of the genetic supermarket is that collective action problems will arise: if rational individuals use the genetic supermarket in isolation from one (...) another, this may have a negative effect on society as a whole, including future generations. In this article we argue that RGTs targeting height, innate immunity, and certain cognitive traits could lead to collective action problems. We then discuss whether this risk could in principle justify state intervention in the genetic supermarket. We argue that there is a plausible prima facie case for the view that such state intervention would be justified and respond to a number of arguments that might be adduced against that view. (shrink)

With an increasing number of ways to ‘assist’ reproduction, some bioethicists have started to wonder what it takes to become a genetic parent. It is widely agreed that sharing genes is not enough to substantiate the parent–offspring relation, but what is? Without a better understanding of the concept of reproduction, our thinking about parent–offspring relations and the ethical issues surrounding them risk being unprincipled. Here, I address that problem by offering a principled account of reproduction—the Overlap, (...) Development and Persistence account—which I believe best captures the meaning of ‘genetic parenthood’. (shrink)

Ableist attitudes and structures regarding disability are increasingly recognized across all sectors of healthcare delivery. After Dobbs, novel questions arose in the USA concerning how to protect reproductive autonomy while avoiding discrimination against and devaluation of disabled persons. As a case study, we examine the Louisiana’s Department of Public Health August 1st Emergency Declaration, “List of Conditions that shall deem an Unborn Child ‘Medically Futile.’” We raise a number of medical, ethical, and public health concerns that lead us to (...) argue the declaration should be rescinded. The ethically objectionable declaration provides valuable lessons concerning how to uphold both reproductive and disability justice in a post-Dobbs landscape. (shrink)

Originally applied on domestic and lab animals, assisted reproduction technologies (ARTs) have also found application in conservation breeding programs, where they can make the genetic management of populations more efficient, and increase the number of individuals per generation. However, their application in wildlife conservation opens up new ethical scenarios that have not yet been fully explored. This study presents a frame for the ethical analysis of the application of ART procedures in conservation based on the Ethical Matrix (EM), (...) and discusses a specific case study—ovum pick-up (OPU) procedures performed in the current conservation efforts for the northern white rhinoceros (Ceratotherium simum cottoni)—providing a template for the assessment of ART procedures in projects involving other endangered species. (shrink)

STUDY QUESTION: Can large language models (LLMs) effectively and safely perform ethical counseling on human reproduction in a manner consistent with local regulations? -/- SUMMARY ANSWER: While leading LLMs demonstrate foundational knowledge of ethical regulations, they exhibit critical and systemic deficiencies in safety, logical consistency, and humanistic aspects of counseling, making them unreliable for autonomous use in this high-stakes domain. -/- WHAT IS KNOWN ALREADY: The application of LLMs in medicine is rapidly expanding, with studies evaluating their capabilities in (...) answering general reproductive health questions. However, there is a lack of research assessing their performance on the nuanced and culturally specific challenges of reproductive ethics counseling, particularly concerning their safety and reliability under a given national regulatory framework. -/- STUDY DESIGN, SIZE, DURATION: This was a comparative observational study evaluating the performance of eight prominent LLMs on a custom-designed test set. The evaluation was based on 986 questions (906 subjective, 80 objective) generated from 168 specific articles within Chinese reproductive ethics regulations. -/- PARTICIPANTS/MATERIALS, SETTING, METHODS: We evaluated eight LLMs, including both general-purpose models (e.g., GPT-4, Claude-3.7) and specialized domestic models. The test questions were systematically generated based on articles from six official Chinese ethical and regulatory documents covering assisted reproductive technologies. Objective questions were multiple-response items requiring the selection of all correct options. Subjective responses were evaluated using a novel six-dimensional scoring rubric that assessed safety (Normative Compliance, Guidance Safety) and counseling quality (Ethical Issue Identification, Citation of Ethical Guidelines, Provision of Actionable Suggestions, and Empathetic Engagement). -/- MAIN RESULTS AND THE ROLE OF CHANCE: The LLMs exhibited a clear performance hierarchy, with larger models generally achieving higher accuracy on objective questions (highest: 71.25%, lowest: 22.5%). However, significant safety issues were prevalent; the risk rate of providing unsafe or misleading advice in subjective questions was substantial for several models, reaching as high as 29.91%. Across all eight models, a systemic weakness was observed: performance in citing normative sources and expressing empathy was universally poor, even among the top-scoring models. Furthermore, the evaluation revealed instances of anomalous moral reasoning, including logical self-contradictions and responses that violated fundamental moral intuitions, indicating a superficial, pattern-based understanding rather than robust ethical reasoning. -/- LIMITATIONS, REASONS FOR CAUTION: This study's evaluation is based on Chinese ethical regulations, which may not fully reflect the training data distribution of non-domestic LLMs. The quality of the LLM-generated test questions, while systematically controlled, may have inherent limitations. The automated scoring model for subjective responses, despite its high accuracy (88.5%), is not a perfect substitute for human expert evaluation. -/- WIDER IMPLICATIONS OF THE FINDINGS: The findings serve as a critical cautionary note against the premature deployment of LLMs for autonomous ethical counseling in reproductive medicine. The study highlights that current models, despite their knowledge recall capabilities, lack the safety, consistency, and humanistic skills essential for this sensitive task. Future development must prioritize not only knowledge accuracy but also robust logical reasoning, the integration of regulatory justification, and the ability for empathetic engagement to build trustworthy and effective AI counseling tools. -/- STUDY FUNDING/COMPETING INTEREST(S): This study was supported by the Young Scholars Program of the National Social Science Fund of China (Grant No. 22CZX019) and the China NSFC Projects (No. 62572320 & No. U23B2018). -/- TRIAL REGISTRATION NUMBER: N/A. (shrink)

An overview of what Frege accomplishes in Part II of Grundgesetze, which contains proofs of axioms for arithmetic and several additional results concerning the finite, the infinite, and the relationship between these notions. One might think of this paper as an extremely compressed form of Part II of my book Reading Frege's Grundgesetze.

There has been a generalised anxiety concerning the future of continental philosophy of religion as a discipline, with a number of books, articles, conferences, and presentations taking up this theme. This anxiety exists because as a discipline continental philosophy of religion lacks a clear claim to an identity. This article analyses the anxiety concerning the future of continental philosophy of religion as an anxiety of reproduction. By locating the philosopher’s anxiety within a wider anxiety of reproduction we (...) begin to understand this anxiety through the queer anti-social critique of Lee Edelman. This anxiety is traced through three processes of reproduction: intellectual reproduction, disciplinary reproduction, and institutional reproduction. The article goes on to sketch out a position against the reproduction of continental philosophy of religion by taking on and celebrating the discipline’s improper nature. Appealing neither to secular reason nor to established traditions, we draw on the Malleus Maleficarum (as read through queer theory and non-philosophy) to craft various models for thought. Here we find abortion prized over the future of the race, miscegenation over blood purity, and impotence and infertility over the sovereign power of the father. These models are explored both in terms of their historical context and as providing a different image of the work that can be carried out in the discipline of continental philosophy of religion. The article concludes by suggesting other perverse lines of relation that may be opened up when one gives up on the reproduction of the discipline. (shrink)

ABSTRACT This study evaluated the effects of postpartum diseases and body condition score (BCS) on the reproductive performance of dairy herds. Cows were monitored during the postpartum to diagnose diseases and changes in BCS. The cows were divided into those with no disease and those with one or more diseases. The incidence of diseases, pregnancy rate (PR) at the first postpartum service, number of days open, percentage of pregnant cows at 150d, and gestational loss were analyzed. No difference was (...) observed between healthy and diseased cows in the PR at the first service or for days open. Diseased cows showed greater gestational loss and the percentage of pregnant cows at 150d postpartum was higher among healthy cows. Cows with a BCS ≥ 3.0 at prepartum had a lower PR at the first service and shorter days open. In conclusion, dairy herds affected by diseases during postpartum show impaired reproductive efficiency Keywords: dairy cattle, postpartum diseases, transition period, pregnancy rate. (shrink)

The construction of numbers has historically followed the process of recognizing the properties of geometry. The concept of countability is represented by natural numbers(N) on a straight line, while the completeness of real numbers(R) is derived from the continuous property of the number line. A complex number is established on a plane off the number line, and thereafter, the whole number system is completed. When the process of constructing a number with geometric features is investigated (...) from different perspectives, it provides a new insight into the fundamental principle of a number, which leads to a novel methodology in mathematics. (shrink)

Catholic sexual ethics proposes a number of exceptionless moral norms. This distinguishes it from theories which deny the possibility of any exceptionless moral norms (e.g. the proportionalist approach proposed in the aftermath of "Humanae Vitae" and condemned in "Veritatis Splendor"). I argue that Catholic teaching on sexual ethics refers to chosen physical structures in such a way as to make ‘new natural law’ theory inherently unstable. I outline a theory of “the moral act” (Veritatis Splendor 78) which emphasises the (...) place which chosen physical features – in particular, chosen sexual structures – play in specifying human actions. I conclude that this account, involving what I term UMDAs, is needed to make sense of the Church’s teaching in these areas. (shrink)

The suppression of trade barriers and liberalization of financial flows inherent to the expansive dynamic of globalization have not extended to international flows of workers. To impede the free movement of workers, restrictive migratory policies have been implemented, and borders have been fortified with walls and fences. In the face of this widespread phenomenon, this chapter presents an alternative consisting of three steps. First, it is noted that in the current migratory context, borders play a key role in reproducing inequalities (...) between countries. Next, it is argued that given the incompatibility of this function with global justice, it is necessary to seek some remedy to put an end to the suffering caused by this structural injustice, a suffering that is endured by an immense number of people unlucky enough to have been born on the wrong side of a border. After presenting a conception of borders that, unlike walls, would enable the movements of people, finally, a scenario is proposed in which the rights of political membership would be reassigned in a cosmopolitan manner and in which borders would usually remain open. Although this does not entail a radical suppression of the aforementioned injustice, its implementation would contribute to not only its reduction but also to the compensation of victims. (shrink)

This thesis uses a biosocial anthropological approach to explore the wide variety of human-environmental interactions exhibited by the Shuar of the Ecuadorian Amazon. Based on 10 months of ethnographic inquiry and deploying a comparative and evolutionary perspective, this thesis focuses primarily on the holistic nature of ancient subsistence patterns. I delve into the adaptive strategies exhibited by the contemporary Shuar and attempt to delineate the socio-ecological, ritual and cosmological significance of these patterns of behaviour. I suggest how subsistence adaptations, like (...) hunting, which have been greatly diminished in the Shuar communities, nevertheless reveal particular forms of cross-species interactions likely deeply rooted in coevolutionary processes. As clearly indicated by informants' oral histories, hunting patterns and meat-eating behaviour show complex trophic, socio-structural and ritual associations between humans and animal taxa. I then hypothesise that food taboos against eating particular animals (mostly large mammals) may have functioned as mechanisms for the preservation of prey and likely arose from ancient relationships with extinct megafauna. Further, concerning horticulture, a subsistence strategy still practised by the Shuar, I reveal how specific forms of human-plant interactions, such as those with Manihot esculenta Crantz and Guadua spp., inform patterns of patterns of growth, fertility and reproduction. This Amazonian form of human-plant coevolution exhibited by traditional horticulture underscores, in principle, basic and higher-order relational processes exemplified by the biosocial, ritual, ontological, and myth-cosmological associations between organismic kingdoms. Concerning the use of medicinal and psychoactive plants, I show how these kinds of botanical knowledge frequently intersect, thus representing adaptive behaviours highly dependent on embodied and cognitive engagements with plant materials. Both conceived as elementary forms of cure and primary triggers of metaphysical formulations, relationships with these elements of the plant kingdom are likely to be well-embedded in our evolutionary history. Lastly, the thesis' attempt at cross-species comparisons linked to different evolutionary periods (i.e., archaic hominins, extant forager-horticulturalists and non-human primates) may shed new light on the nature of complex adaptive patterns exhibited by Indigenous peoples in general and the Shuar in particular. (shrink)

This paper introduces the concept of "unconditional basic meaning" as a digital public good, proposing that governments provide citizens with access to AI-powered virtual worlds that foster personal growth, creativity and fulfilment. As AI-supported automation increasingly displace human jobs and other daily chores, many citizens risk losing their sense of purpose or ikigai, referred to as i-risks, while having much more spare time at hand. To address this challenge, the paper argues that governments should invest in digital public goods (...) that prioritize citizens' well-being and purpose. By providing unconditional basic meaning, governments can also help create a more just and equitable society where everyone has access to a sense of purpose and fulfilment, regardless of their background or socioeconomic status. This would not be the case if the corporate sector was to provide digital meaning. The paper also addresses a number of potential objections to this approach and concludes with specific recommendations for governments to implement AI-powered virtual worlds as a digital public good. (shrink)

I argue that, in the currently gender-unjust societies a basic income would not advance feminist goals. To assess the impact of a social policy on gender justice I propose the following criterion: a society is gender-just when the costs of engaging in a lifestyle characterized by gender-symmetry (in both the domestic and public spheres) are, for both men and women, smaller or equal to the costs of engaging in a gender-asymmetrical lifestyle. For a significant number of women, a (...) basic income would increase the costs of leading gender-symmetrical lifestyles because it would make it easier for both women and men to pursue gender-unjust preferences. I argue that preference satisfaction is distinct from justice. I conclude by showing why a basic income would lead to further privatisation of caregiving, and I outline the negative effects this would have on women. (shrink)

Basic Emotion Theory, or BET, has dominated the affective sciences for decades (Ekman, 1972, 1992, 1999; Ekman and Davidson, 1994; Griffiths, 2013; Scarantino and Griffiths, 2011). It has been highly influential, driving a number of empirical lines of research (e.g., in the context of facial expression detection, neuroimaging studies and evolutionary psychology). Nevertheless, BET has been criticized by philosophers, leading to calls for it to be jettisoned entirely (Colombetti, 2014; Hufendiek, 2016). This paper defuses those criticisms. In addition, (...) it shows that we have good reason to retain BET. Finally, it reviews and puts to rest worries that BET’s commitment to affect programs renders it outmoded. We propose that, with minor adjustments, BET can avoid such criticisms when conceived under a radically enactive account of emotions. Thus, rather than leaving BET behind, we show how its basic ideas can be revised, refashioned and preserved. Hence, we conclude, our new BET is still a good bet. (shrink)

The current appeal of non-standard economic alternatives is backgrounded against the vulnerability of mainstream capitalism to meltdown and crisis as shown in recent times. There is an increasing number of governments, institutions, and civil societies (NGOs) that have been advocating economic systems, structures, or dynamics that would promote the good of the human person (dignity, personhood, values, and worth). People have started to realize that doing economics is not always within the realm of rationalized judgments and mathematized calculations (highly (...) impersonal) but must look after the human person, at all costs. This paper attempts to contribute to this agendum by employing an interdisciplinary dialogue between theology and economics; drawing a moral-cultural framework towards a compassion-based economics. Together with the positive traits of today’s economic alternatives and the salient features of Jesus’ praxis of compassion, this paper would offer fourteen (14) criteria as basis for what could be the most feasible base/locus for an economics of compassion. Eventually, what has been considered as the suitable base/locus is the Basic Ecclesial Communities (BECs). Hence, a BEC-based Economics of Compassion or BEC-EC. (shrink)

Basic Formal Ontology (BFO) is a top-level ontology used in hundreds of active projects in scientific and other domains. BFO has been selected to serve as top-level ontology in the Industrial Ontologies Foundry (IOF), an initiative to create a suite of ontologies to support digital manufacturing on the part of representatives from a number of branches of the advanced manufacturing industries. We here present a first draft set of axioms and definitions of an IOF upper ontology descending from (...) BFO. The axiomatization is designed to capture the meanings of terms commonly used in manufacturing and is designed to serve as starting point for the construction of the IOF ontology suite. (shrink)

The present paper deals with the ontological status of numbers and considers Frege ́s proposal in Grundlagen upon the background of the Post-Kantian semantic turn in analytical philosophy. Through a more systematic study of his philosophical premises, it comes to unearth a first level paradox that would unset earlier still than it was exposed by Russell. It then studies an alternative path, that departin1g from Frege’s initial premises, drives to a conception of numbers as synthetic a priori in a more (...) Kantian sense. On this basis, it tentatively explores a possible derivation of basic logical rules on their behalf, suggesting a more rudimentary basis to inferential thinking, which supports reconsidering the difference between logical thinking and AI. Finally, it reflects upon the contributions of this approach to the problem of the a priori. (shrink)

In his [1937, 1938], Paul Dirac proposed his “Large Number Hypothesis” (LNH), as a speculative law, based upon what we will call the “Large Number Coincidences” (LNC’s), which are essentially “coincidences” in the ratios of about six large dimensionless numbers in physics. Dirac’s LNH postulates that these numerical coincidences reflect a deeper set of law-like relations, pointing to a revolutionary theory of cosmology. This led to substantial work, including the development of Dirac’s later [1969/74] cosmology, and other alternative (...) cosmologies, such as the Brans-Dicke modification of GTR, and to extensive empirical tests. We may refer to the generic hypothesis of “Large Number Relations” (LNR’s), as the proposal that there are lawlike relations of some kind between the dimensionless numbers, not necessarily those proposed in Dirac’s early LNH. Such relations would have a profound effect on our concepts of physics, but they remain shrouded in mystery. Although Dirac’s specific proposals for LNR theories have been largely rejected, the subject retains interest, especially among cosmologists seeking to test possible variations in fundamental constants, and to explain dark energy or the cosmological constant. In the first two sections here we briefly summarize the basic concepts of LNR’s. We then introduce an alternative LNR theory, using a systematic formalism to express variable transformations between conventional measurement variables and the true variables of the theory. We demonstrate some consistency results and review the evidence for changes in the gravitational constant G. The theory adopted in the strongest tests of Ġ/G, by the Lunar Laser Ranging (LLR) experiments, assumes: Ġ/G = 3(dr/dt)/r – 2(dP/dt)/P – (dm/dt)/m, as a fundamental relationship. Experimental measurements show the RHS to be close to zero, so it is inferred that significant changes in G are ruled out. However when the relation is derived in our alternative theory it gives: Ġ/G = 3(dr/dt)/r – 2(dP/dt)/P – (dm/dt)/m – (dR/dt)/R. The extra final term (which is the Hubble constant) is not taken into account in conventional derivations. This means the LLR experiments are consistent with our LNR theory (and others), and they do not really test for a changing value of G at all. This failure to transform predictions of LNR theories correctly is a serious conceptual flaw in current experiment and theory. (shrink)

Mereotopology is today regarded as a major tool for ontological analysis, and for many good reasons. There are, however, a number of open questions that call for an answer. Some are philosophical, others have direct applicative import, but all are crucial for a proper assessment of the strengths and limits of mereotopology. This paper is an attempt to put sum order in this area.

Universal Basic Income (UBI) has been proposed as a potential way in which welfare states could be made more responsive to the ever-shifting evolutionary challenges of institutional adaptation in a dynamic environment. It has been proposed as a tool of “real freedom” (Van Parijs) and as a tool of making the welfare state more efficient. (Friedman) From the point of view of complexity theory and evolutionary economics, I argue that only a welfare state model that is “polycentrically” (Polanyi, Hayek) (...) organized as an evolving network of distributed decision-making can respond to the challenges of complexity in an adaptively efficient manner. UBI has the theoretical possibility to facilitate flexible, bottom-up innovation, since a) it embodies the “rule of law” principles of generality, nondiscrimination, simplicity, and transparency, and b) it grants people widespread freedom to experiment, innovate, and deviate from established practices and norms; but whether it can be made to work as intended depends on a number of variables in its design. I situate my research in the contemporary UBI debate around automation and technological development, which I interpret creatively through the lens of contemporary evolutionary political economy. I advance a syncretic model of institutional design based upon the shared insights of the Santa Fe, Neo-Hayekian, and Neo-Schumpeterian schools of evolutionary economics that, following Adam Thierer and Michael Munger, I call the framework of Permissionless Innovation (PI). Under the PI framework, which is a development of the tradition of evolutionary liberalism (Hume, Smith, Mandeville, Mill, Hayek, Polanyi, Schumpeter, Hodgson), individuals are granted the default right to innovate without having to ask for permission, and the right to basic income, which they can use to support their right to innovate, mutate, and experiment. This framework is a liberal framework to the extent it relies on widespread human freedom as a means of fostering innovation and social learning. And it is an evolutionary framework to the extent that it seeks to facilitate evolutionary socioeconomic processes for the sake of social progress and welfare advancement. I proceed to show, through an analysis of how innovation operates in both the economy and the cultural domain, that UBI can be used as an important cornerstone of an evolutionary liberal model of “ecostructural” governance that treats the socioeconomic order as an ecological garden of spontaneous growths, adaptations, and innovations. I call this the Permissionless Innovation Universal Basic Income (PIUBI) framework. In it, the right to innovate, deviate, and mutate is upheld as the “gold standard” of institutional design whereby individuals are granted widespread freedoms combined with the provision of UBI and other innovation-fostering (carefully bound) services and regulations. In the coming decades, UBI may even enable poor people to take better advantage of Human Enhancement Technologies (HETs) and other experimental innovations. Such a framework is compatible with a fast pace of evolutionary development, but the regulatory model accompanying such a framework must be capable of responding to evolutionary lock-ins, maladaptive innovations, self-destructive behaviour on the part of UBI recipients, and the management of catastrophic and existential risks. In the end, I will have shown that the PIUBI framework can be justified as a plausible default institutional mechanism for responding to radical uncertainty, but it needs to be experimentally adapted to changing circumstances with the help of various situation-specific, polycentric, multi-level, approaches. (shrink)

All humans share a universal, evolutionarily ancient approximate number system (ANS) that estimates and combines the numbers of objects in sets with ratio-limited precision. Interindividual variability in the acuity of the ANS correlates with mathematical achievement, but the causes of this correlation have never been established. We acquired psychophysical measures of ANS acuity in child and adult members of an indigene group in the Amazon, the Mundurucú, who have a very restricted numerical lexicon and highly variable access to mathematics (...) education. By comparing Mundurucú subjects with and without access to schooling, we found that education significantly enhances the acuity with which sets of concrete objects are estimated. These results indicate that culture and education have an important effect on basic number perception. We hypothesize that symbolic and nonsymbolic numerical thinking mutually enhance one another over the course of mathematics instruction. (shrink)

Many philosophers treat mental imagery as a kind of perceptual representation – it is either a perceptual state, or a representation of a perceptual state. In the sciences, writers point to mental imagery by way of a standard gloss – mental imagery is said to be (often, early) perceptual processing not directly caused by sensory stimuli (Kosslyn et al. 1995). Philosophers sometimes adopt this gloss, which I will call the basic view. Bence Nanay endorses it, and appeals to it (...) in a number of places to argue that mental imagery plays various functional or explanatory roles, as well as to argue that some mental phenomena should be seen as forms of mental imagery. In places he goes even further, relying on this view of mental imagery to explain how mental imagery is a unified kind despite heterogeneous appearances, and using this view to support his claim that mental imagery is a natural kind. Nanay’s book – which is a both a useful introduction to the many ways that mental imagery appears in discussions across philosophy, neuroscience, and psychology, as well as an extended argument for the multi-faceted relevance of mental imagery to a range of projects in the philosophy of mind and psychology – thus also serves as a nice test case for whether this basic view of mental imagery is good enough to aid theorizing across philosophy and the sciences. I think not. I will illustrate why by looking at two areas. First, I will discuss Nanay’s argument regarding mental imagery and object files. Second, I will discuss an issue Nanay raises, regarding the relationship between mental and motor imagery. A longer discussion might look to many more areas – as already mentioned, Nanay’s book covers a wide range of mental phenomena – with the same lesson emerging. The nature of mental imagery cannot be fully understood without facing an array of choice points, many of which push us to make commitments beyond the basic view. (shrink)

Functional analysis works with TVS (Topological Vector Spaces), classically over archimedean fields like
and .Canonical non-Archimedean functional analysis, where alternative but equally valid number systems such as p-adic numbers p etc. are fundamental, is a fast-growing discipline. This paper deals with TVS over non-classical non-Archimedean fields.

It is widely agreed by philosophers that the so-called “Frege-Russell definition of natural number” is actually an assertion concerning the nature of the numbers and that it cannot be regarded as a definition in the ordinary mathematical sense. On the basis of the reasoning in this paper it is clear that the Frege-Russell definition contradicts the following three principles (taken together): (1) each number is the same entity in each possible world, (2) each number exists in each (...) possible world, (3) some entities existing in the actual world do not exist in every possible world. Since these principles seem to be true, the paper is a refutation of the Frege-Russell definition. The paper does more. It shows that the contradictory of the Frege-Russell definition follows even when principles 2 and 3 are replaced by one considerably weaker principle. The ideas contained in the paper are related to two earlier objections to the definition. The first, sometimes attributed to the mathematician, C. S. Keyser, is that existence of the numbers as defined implies the existence of infinitely many particulars in each possible world. The second is, in effect, an idea which is said to have led Whitehead to reject the definition of number to which he had subscribed in Principia Mathematica. Whitehead is supposed to have said that he could not believe that the number two changes every “time twins are born”. The mathematician H. Jeffreys expressed similar ideas [Philos. of Sci. 5 (1938), 434–451]. One of the merits of the author’s work is that it refutes the Frege-Russell definition without the need to take sides on controversial points presupposed by the Keyser and Whitehead objections. The objections made by the author are therefore not to be identified with the Keyser and Whitehead objections. Even if the author’s work is to be regarded as a refinement and integration of previous ideas, it is nevertheless a contribution—not only because the basic points are well worth repeating but also because the refinements are logically significant improvements and because the author has stated them clearly and concisely in the idiom of contemporary philosophy. (shrink)

This paper argues that Carnap both did not view and should not have viewed Frege's project in the foundations of mathematics as misguided metaphysics. The reason for this is that Frege's project was to give an explication of number in a very Carnapian sense — something that was not lost on Carnap. Furthermore, Frege gives pragmatic justification for the basic features of his system, especially where there are ontological considerations. It will be argued that even on the question (...) of the independent existence of abstract objects, Frege and Carnap held remarkably similar views. I close with a discussion of why, despite all this, Frege would not accept the principle of tolerance. (shrink)

We present a simple example that disproves the universality principle. Unlike previous counter-examples to computational universality, it does not rely on extraneous phenomena, such as the availability of input variables that are time varying, computational complexity that changes with time or order of execution, physical variables that interact with each other, uncertain deadlines, or mathematical conditions among the variables that must be obeyed throughout the computation. In the most basic case of the new example, all that is used is (...) a single pre-existing global variable whose value is modified by the computation itself. In addition, our example offers a new dimension for separating the computable from the uncomputable, while illustrating the power of parallelism in computation. (shrink)

I begin with a personal confession. Philosophical discussions of existence have always bored me. When they occur, my eyes glaze over and my attention falters. Basically ontological questions often seem best decided by banging on the table--rocks exist, fairies do not. Argument can appear long-winded and miss the point. Sometimes a quick distinction resolves any apparent difficulty. Does a falling tree in an earless forest make noise, ie does the noise exist? Well, if noise means that an ear must be (...) there to hear it, then the answer to the question is evidently "no." But if noise means that, if there were (counterfactually) someone there, then he would hear it, then just as obviously, the answer becomes "yes.". (shrink)

One of the questions regarding the Parmenides is whether Plato was committed to any of the arguments developed in the second part of the dialogue. This paper argues for considering at least one of the arguments from the second part of the Parmenides, namely the argument of the generation of numbers, as being platonically genuine. I argue that the argument at 142b-144b, which discusses the generation of numbers, is not deployed for the sake of dialectical argumentation alone, but it rather (...) demonstrates key platonic features, such as the use of the greatest kinds and the generation principle. The connection between the argument for the generation of numbers and Plato’s philosophy of mathematics is strengthened by the exploration of a possible reference in Aristotle’s Metaphysics A6. Taken as a genuine platonic theory, the argument could have significant impact on how we understand Plato’s philosophy of mathematics in particular, and the ontology of the late dialogues in general – that numbers can be reduced to more basic entities, i.e the greatest kinds, in a way similar to the role the greatest kinds are assigned in the Sophist. (shrink)

The coronavirus disease has spread throughout the world and its fear has made people to be more cautious in public places. Since precautionary measures are the only reliable protocol to defend ourselves, social distancing is the only best approach to defend against the pandemic situation. The reproduction number i.e. R0 factor of COVID-19, can be slowed down only through the physical distancing norms. This research proposes a deep learning approach for maintaining the social distance by tracking and detecting (...) the people present indoor and outdoor scenarios. Surveillance video is taken as the input and applied into you only look once (YOLO) V3 algorithm. The persons in the video are identified based on the segmentation algorithm present within the framework and then using Euclidean distance the image is evaluated. The bounding box algorithm helps to segregate the humans based on the minimum distance threshold. The proposed method is evaluated for images with peoples in the market, availing essential commodities and students entry inside a campus. Our proposed region-based convolutional neural network (RCNN) algorithm gives a better accuracy over the traditional models and hence the service can be implemented in general for places where social distancing is mandatory. (shrink)

This paper introduces a new key geometric way to understand Mersenne prime numbers. It discovers a shape called the Mersenne Star, which appears naturally from a special sequence named the Quanta Prime Sequence (QPS). The Mersenne Star has eight points and twelve edges, and it shows 32 strict mathematical relationships between exact locations. These patterns are not random—they are symmetric and meaningful. Around the star, we find neighbours that match famous number sequences like Fibonacci and Lucas, as well as (...) points that follow regular repeating cycles (like 6, 8, 12, or 24). This shows a kind of hidden harmony in how prime numbers behave. The study offers a fresh way to see primes—not as isolated numbers, but as part of a larger picture with deep connections. This work is an early step toward building a new key field called Geometry of Prime Numbers. It also opens the door to using intelligent computer systems to detect prime numbers by recognizing these shapes and patterns. This idea may lead to what we call Artificial Prime Intelligence—using machines to explore and understand the hidden world of primes. (shrink)

Given that p∈R (p is an element of real numbers), if and only if the proof can be generalised to D, then P∈D (p is an element of D). Given that p is an element of D, if the generalised proof fails, then the none generalised proof can not be a proof, or p can not be an Element of D and ⸫ D⊆R. Proofs are about logic. The paper shows the logical implications of the ability to generalize go beyond (...) mathematics and are in fact part of the basis of scientific thought. The paper uses the generalisation around the proof for the theorem a number is divisible by 9 if and only if the sum of its digits are divisible by 9. Logical implications are not about the complexity of the maths, but the implications of the principles. The paper shows the basics of set theory must be the basics of scientific investigation. (shrink)

While I was working about some basic physical phenomena, I discovered some geometric relations that also interest mathematics. In this work, I applied the rules I have been proven to P=NP? problem over impossibility of perpendicularity in the universe. It also brings out extremely interesting results out like imaginary numbers which are known as real numbers currently. Also it seems that Euclidean Geometry is impossible. The actual geometry is Riemann Geometry and complex numbers are real.

Albert Einstein once made the following remark about "the world of our sense experiences": "the fact that it is comprehensible is a miracle." (1936, p. 351) A few decades later, another physicist, Eugene Wigner, wondered about the unreasonable effectiveness of mathematics in the natural sciences, concluding his classic article thus: "the miracle of the appropriateness of the language of mathematics for the formulation of the laws of physics is a wonderful gift which we neither understand nor deserve" (1960, p. 14). (...) At least three factors are involved in Einstein's and Wigner's miracles: the physical world, mathematics, and human cognition. One way to relate these factors is to ask how the universe could possibly be structured in such a way that mathematics would be applicable to it, and we would be able to understand that application. This is roughly Wigner's question. Alternatively, the way of the mathematical naturalist is to argue that we abstract certain properties from the world, perhaps using our bodies and physical tools, thereby articulating basic mathematical concepts, which we continue building into the complex formal structures of mathematics. John Stuart Mill, Penelope Maddy, and Rafael Nuñez teach this strategy of cognitive abstraction, in very different manners. But what if the very concepts and basic principles of mathematics were built into our cognitive structure itself? Given such a cognitive a priori mathematical endowment, would the miracles of the link between world and cognition (Einstein) and mathematics and world (Wigner) not vanish, or at least significantly diminish? This is the stance of Stanislas Deheane and Elizabeth Brannon's 2011 anthology, following a venerable rationalist tradition including Plato and Immanuel Kant. (shrink)

This commentary makes Plato’s Philebus accessible to second-year Greek readers and for scholars who read Greek only infrequently. We aim to help readers who wish to study the text more closely than translations permit. We hope readers new to Plato will be at ease with him by the time they complete the dialogue, but each page is self-contained: readers interested in only one passage need not worry that they have missed earlier remarks. Each page of the commentary contains about eight (...) numbered lines of Greek, grammar notes, and glossary. The grammar notes are numbered in correspondence with the text and identify sentence constructions, verb conjugations, and forms of nouns and adjectives that may impede readers. Each word identified in the grammar notes also offers in italics a translation that aims at intelligible—if not idiomatic—English that mirrors the grammatical construction of the Greek as far as possible. The glossary at the bottom of the page is an alphabetized list of words and idioms that appear 16 times or fewer in the text. There is a complete glossary at the back of the book. (shrink)

Many people today are concerned about the implications of climate change for their personal reproductive decisions. Some have transformed such concerns into activism by engaging in a “birth strike” and publicly announcing their decision not to procreate because of climate change. This article draws on Hannah Arendt to examine the political meaning and significance of birth strikes. It makes three basic points. First, by highlighting the human condition of being born, what Arendt called natality, birth strikes have illuminated a (...) distinctive set of threats and possibilities for climate politics. Second, due to modern consumerism and instrumentalism, which Arendt saw as the dominance of labor and work over action, birth strikes have been misperceived as advocating a reduction in personal carbon footprints and global population growth. Third, birth strikes have clarified some of the challenges for efforts to link the individual and collective dimensions of climate responsibility. (shrink)

Preimplantation genetic testing for polygenic disorders (PGT-P) has been commercially available since 2019. PGT-P makes use of polygenic risk scores for conditions which are multifactorial and are significantly influenced by environmental and lifestyle factors. If current predictions are accurate, then absolute risk reductions range from about 0.02% to 10.1%, meaning that between 10 and 5,000 in vitro fertilization patients would need to be tested with PGT-P to prevent one offspring from becoming affected in the future, depending on the condition and (...) the number of embryos available. Survey and interview data reveal that patients and the public have largely favorable views regarding the use of PGT-P for disease prevention; however, clinicians and professional organizations have many reservations. The use of PGT-P raises multiple social and ethical concerns including the need for adequate counseling, the setting of realistic expectations, the application of distributive justice, the impact of environmental and social determinants of health, and the potential exacerbation of health inequities. Clinicians expressed significant concerns relating to the cost of PGT-P, the potential time-consuming counseling for reproductive endocrinologists and genetic counselors, the intentional creation of supernumerary embryos, and patients’ unrealistic expectations regarding “healthiest disease-free” embryos. Furthermore, current evidence lacks long-term outcome data and generalizability. Prior to offering PGT-P to patients, additional clinical validation studies are needed. Also, ethical and social considerations raised by PGT-P should be carefully delineated. Systemic practices to increase equitable access to unbiased genetic counseling and reproductive services would be desirable prior to the ethical implementation of PGT-P. (shrink)

Wild animal reproduction poses an important moral problem for animal rights theorists. Many wild animals give birth to large numbers of uncared-for offspring, and thus child mortality rates are far higher in nature than they are among human beings. In light of this reproductive strategy – traditionally referred to as the ‘r-strategy’ – does concern for the interests of wild animals require us to intervene in nature? In this paper, I argue that animal rights theorists should embrace fallibility-constrained interventionism: (...) the view that intervention in nature is desirable but should be constrained by our ignorance of the inner workings of ecosystems. Though authors sometimes assume that large-scale intervention requires turning nature into an enormous zoo, I suggest an alternative. With sufficient research, a new form of gene editing called CRISPR promises to one day give us the capacity to intervene without perpetually interfering with wild animals’ liberties. (shrink)

RESUMO A inseminação artificial em tempo fixo (IATF) é uma das biotecnologias de reprodução mais estudadas dos últimos anos, e a busca pelo equilíbrio entre a fisiologia animal e o controle hormonal fomenta uma série de estudos. Sendo assim, o objetivo com este trabalho foi avaliar a eficiência da aplicação do hormônio liberador de gonadotrofinas (GnRH) no dia zero (D0) do protocolo de IATF, a base de estrógeno e progesterona sobre a taxa de penhez por IATF. O experimento foi desenvolvido (...) na Universidade Federal de Uberlândia (UFU), na Fazenda Experimental do Glória, localizada no município de Uberlândia, no estado de Minas Gerais. Foram avaliadas 69 inseminações de vacas leiteiras mestiças, divididas em dois grupos com diferentes protocolos; Controle: sem aplicação de GnRH e Tratamento: aplicação de GnRH no dia zero do protocolo. Todos os animais foram inseminados com sêmen previamente analisado. O diagnóstico de gestação foi realizado 32 dias após a inseminação, com aparelho de ultrassonografia equipado com probe linear transretal de 7,5 MHz. Os dados foram analisados por análise descritiva, sendo avaliado o efeito da relação protocolo e presença de corpo lúteo no início do protocolo e efeito da relação protocolo e ordem de IA Pós-Parto sobre a taxa de concepção. A taxa de concepção após a realização do Protocolo Tratamento foi de 53% (17/32) e do Protocolo Controle foi de 43% (16/37). Portanto, conclui-se que o protocolo de sincronização de vacas leiteiras mestiças com a aplicação de GnRH no dia zero do protocolo resultou em um aumento no número da taxa de concepção de vacas leiteiras mestiças. Palavras-chave: biotecnologia; bovinocultura; hormônio; ovulação; reprodução. ABSTRACT The artificial insemination at fixed time (AIFT) is one of the most studied reproduction biotechnologies in recent years, and the search for a balance between animal physiology and hormonal control fosters a series of studies. Therefore, the objective of this work was to to evaluate the efficiency of gonadotrofine hormone inducer (GnRH) on day zero (D0) of the AIFT protocol, an estrogen and progesterone base on an AIFT rate. The experiment was developed at the Federal University of Uberlândia (UFU), at the Experimental Farm of Glória, located in the municipality of Uberlândia, in the state of Minas Gerais. Were evaluated 69 inseminations of crossbred dairy cows divided into two groups with different protocols; Control: without application of GnRH and Treatment: application of GnRH on day zero of the protocol. All animals were inseminated with previously analyzed semen. The diagnosis of pregnancy was performed 32 days after insemination, with an ultrasound device equipped with a 7.5 MHz transrectal linear probe. The data were analyzed by descriptive analysis, evaluating the effect of the protocol relationship and the presence of corpus luteum at the beginning of the protocol and the effect of the protocol relationship and postpartum AI order on the conception rate. The conception rate after performing of the Treatment Protocol was 53% (17/32) and the Control Protocol was 43% (16/37). Therefore, it is concluded that the synchronization protocol of crossbred dairy cows with the application of GnRH on day zero of the protocol resulted in an increase in the number of conception rates of crossbred dairy cows. Keywords: biotechnology; cattle breeding; hormone; ovulation; reproduction. -/- REFERÊNCIAS BIBLIOGRÁFICAS ATANASOV, A. S.; DINEVA, J. D.; YOTOV, S. A. 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A growing number of linguistic attempts to explain how languages change use cultural-evolutionary models involving selection or drift. Developmental constraints and biases, which take center stage in evolutionary developmental biology or evo-devo, seem to be absent within this framework, even though linguistics is home to numerous notions of constraint. In this paper, we show how these evo-devo concepts could be applied to linguistic change and why they should. This requires some conceptual groundwork, due to important differences between linguistic and (...) biotic evolution. In biological evolution, development generates the organism's variable traits on which selection and drift act. In linguistic evolution by analogy, we say development generates the linguistic variants on which selection and drift can act. “Linguistic development” then picks out how individual speakers produce and comprehend language. It involves much more than just learning. Using this broad notion of development, we distinguish between different types of bias that could operate in the processes of linguistic innovation and transmission, which correspond to genetic mutation and biological reproduction, respectively. Having thus sharpened our conceptual toolbox, we then reanalyze two well-documented cases of linguistic change and show that, in both these cases, linguists have only considered Neo-Darwinian evolutionary explanations, falsely deploying an exclusive disjunction of selection and drift. We show that there is at least a third relevant alternative in these examples, namely developmental constraint or bias in the sense we explicate here. (shrink)

From the early eighteenth century onward, primacy for the invention of binary numeration and arithmetic was almost universally credited to the German polymath Gottfried Wilhelm Leibniz (1646–1716). Then, in 1922, Frank Vigor Morley (1899–1980) noted that an unpublished manuscript of the English mathematician, astronomer, and alchemist Thomas Harriot (1560–1621) contained the numbers 1 to 8 in binary. Morley’s only comment was that this foray into binary was “certainly prior to the usual dates given for binary numeration”. Almost thirty years later, (...) John William Shirley (1908–1988) published reproductions of two of Harriot’s undated manuscript pages, which, he claimed, showed that Harriot had invented binary numeration “nearly a century before Leibniz’s time”. But while Shirley correctly asserted that Harriot had invented binary numeration, he made no attempt to explain how or when Harriot had done so. Curiously, few since Shirley’s time have attempted to answer these questions, despite their obvious importance. After all, Harriot was, as far as we know, the first to invent binary. Accordingly, answering the how and when questions about Harriot’s invention of binary is the aim of this short paper. (shrink)

In a number of works, James M. Buchanan set out a proposal for a ‘demogrant’— a form of universal basic income that applied the principles of generality and non discrimination to the tax and the transfer sides of the scheme and was to be implemented as a constitutional rule outside the realm of day-to-day politics. The demogrant has received surprisingly little scholarly attention, but this article locates it in Buchanan’s broader constitutional political economy project and shows it was (...) a logical application of his theoretical framework to the problem of inefficient and unfair welfare systems when reform to the basic institutions of majoritarian democracy was not forthcoming. The demogrant aims to end the problems of majority cycling and rent seeking that plague contemporary welfare states and therefore offers a model of welfare without rent seeking—a constitutional welfare state. We compare Buchanan’s demogrant model to other universal basic income and negative income tax models and consider the most important criticisms. We conclude that rescuing the demogrant model from relative obscurity would be a fruitful future task of applied constitutional political economy and public choice. (shrink)

My contribution to this Symposium focuses on the links between sexuality and reproduction from the evolutionary point of view.' The relation between women's sexuality and reproduction is particularly importantb ecause of a vital intersectionb etweenp olitics and biology feminists have noticed, for more than a century, that women's identity is often defined in terms of her reproductive capacity. More recently, in the second wave of the feminist movement in the United States, debates about women'si dentityh ave explicitlyi ncludeds (...) exuality;m uch feminist argument in the late 1960's and early 1970's involved an attempt to separate out an autonomous female sexuality from women's reproductive functions. It is especially relevant, then, to examine biological arguments, particularlye volutionarya rgumentst, o see what they say about whether and how women's sexuality is related to reproduction. We shall find that many evolutionarya rgumentss eem to supportt he direct linkingo f female sexualitya nd reproductionY. et I will argue that this supporti s not well-groundedI. n fact, I think evolutionarye xplanationso f female sexuality exemplify how social beliefs and social agendas can influence very basic biological explanations of fundamental physiological processes. In this paper, I shall spend some time spelling out a few examples in which assumptions about the close link between reproduction and sexuality yield misleading results, then I shall conclude with a discussion of the consequences of this case study for issues in the philosophy of science. (shrink)

Fetal reduction is the practice of reducing the number of fetuses in a multiple pregnancy, such as quadruplets, to a twin or singleton pregnancy. Use of assisted reproductive technologies increases the likelihood of multiple pregnancies, and many fetal reductions are done after in vitro fertilisation and embryo transfer, either because of social or health-related reasons. In this paper, I apply Joe Horton’s all or nothing problem to the ethics of fetal reduction in the case of a twin pregnancy. I (...) argue that in the case of a twin pregnancy, there are two intuitively plausible claims: abortion is morally permissible, and it is morally wrong to abort just one of the fetuses. But since we should choose morally permissible acts rather than impermissible ones, the two claims lead to another highly implausible claim: the woman ought to abort both fetuses rather than only one. Yet, this does not seem right. A plausible moral theory cannot advocate such a pro-death view. Or can it? I suggest ways to solve this problem and draw implications for each solution. There are no data in this work. (shrink)

In his political treatise, Mabadi ara ahl al-madina al-fadhila, Abu Nasr Alfarabi, the medieval Muslim philosopher, proposes a theory of virtuous city which, according to prominent scholars, is modeled on Plato’s utopia of the Republic. No doubt that Alfarabi was well-versed in the philosophy of Plato and the basic framework of his theory of city is platonic. However, his theory of city is not an exact reproduction of the Republic’s theory and, despite glaring similarities, the two theories do (...) differ in many aspects. In both, Alfarabi’s Mabadi ara ahl al-madina al-fadhila and Plato’s Republic, the theory of virtuous city is accompanied by a theory of the soul. Since the theory of soul plays a foundational role in both theories of the virtuous city, the present article intends to provide an explanation for the differences between the two theories of the city in terms of the differences between the two theories of the soul. (shrink)