Dopamine: Reach out and Touch Someone

As some of you may know by now, Sci blogs a bit about dopamine. Dopamine seems pretty simple at first look (one chemical, one transporter, five receptors, how hard can it be?), but in fact, dopamine modulates a huge number of processes, particularly those related to learning and motivation. We talk a lot about dopamine being a “pleasure” molecule, and in a way it in, but it’s more complicated than that. It’s not just pleasure, it’s motivation and reward processes, which in a way are deeper than just the pleasure you might feel at having sex or eating a pizza. Obviously dopamine can have some pretty big effects on things like, for example, motivated movement (Parkinson’s), or disregulated motivational processes (drug addiction).
But what about touch? Can dopamine levels influence how you process touch, and how well you can do on a test for it?
Pleger, et al. “Influence of dopaminergically mediated reward on somatosenory decision-making” PLoS Biology, 2009.

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Book Review: Jonah Lehrer and How we Decide

A few weeks ago, Sci was lucky enough to receive the latest book from Jonah Lehrer, How We Decide, in the mail! Well, ok, Sci is receiving a LOT of things in the mail. Ever since I went on and on about how much I love getting free books…I get a lot of free books. A lot of heavy science books. Now, don’t get me wrong, Sci loves reading science. But it can get to be…a bit much. Perhaps someday Sci will share with all of you (who I am sure are all PANTING to know) the list of books that Sci is reading which are not science-related. But the science books, the piles of science books, how they do beckon.
But anyway, ONWARD.
Lehrer_How_1.jpg
Sci was really thrilled to get a copy of Jonah’s book, she’d been lusting after one for a while. All I have to do now is come across a copy of “Proust was a Neuroscientist” and I’ll have the complete Jonah set! (*cough cough Jonahsendmeacopyofyourbook cough cough*)

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Cake or Death? It’s all a matter of self-control, and your vmPFC

Cake or Death? Cake, please.
Today’s article comes to you from ars technica, where a friend of the blog found this article from Matt Ford on how we pick our food. Given that Sci is in the middle of reading “How We Decide” by Scienceblogs own Jonah Lehrer, she couldn’t pass this decision-making kind of article up. It was a conscious decision, I think. Or was it?
I don’t know about you, but everyone Sci knows appears to be trying to regulate their diet somewhat. Most of my friends think the word “die” is in the word “diet” for a reason. But we all still try to eat well, though we’re not going to be subsisting on grapefruit and wheatgrass juice any time soon. We’re all hearing the messages that we need to eat lean protein, get lots of fiber, and eat as many fruits and vegetables as we can afford.
The media nowadays is jam packed with advertisements saying we need to make healthy choices, right next to other advertisements letting us know about the many many offerings available at fast food restaurants for less than a dollar. With all this coming into your brain every day, it can be really hard to make the right decisions. Would a granola bar be good right now? Or should you have some fruit instead? Should you eat the chocolate cake or the ice cream?
And these decisions become even harder when it becomes a choice of fruit vs. cake (I don’t know about you guys, but the fruit would be languishing on Sci’s shelf for months). In these cases, your decision making has to have some layers to it. Rather than just “ooooh! Cake!”, you also need to think “eh, but I already HAD chocolate today, and I haven’t had more than one serving of fruit…and I should get more fiber because apparently everyone needs more fiber…”
chocolate cake decision.jpg VS banana decision.jpg
Sorry, Banana. No contest. LOOK at the chocolate shavings on that thing…sigh…
So anyway. Our brains may want cake, and other parts of our brains want healthy. The two sides need to fight. But which areas of your brain are responsible? And how do they modulate each other? That’s what this group wanted to find out.
ResearchBlogging.org Hare et al. “Self-control in decision-making involves modulation of the vmPFC valuation system.” Science, 2009.

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