All Stories

  1. Silicon-based metal-organic frameworks (SiMOFs) for immunogenic cell death in cancer therapy

    Article • Nano Research, January 2025, Tsinghua University Press

    Samuel Y. Sheng Professor Kam W Leong

  2. Magnetic soft microrobots for erectile dysfunction therapy

    Article • Proceedings of the National Academy of Sciences, November 2024, Proceedings of the National Academy of Sciences

    Samuel Y. Sheng Professor Kam W Leong

  3. Focused ultrasound–mediated brain genome editing

    Article • Proceedings of the National Academy of Sciences, August 2023, Proceedings of the National Academy of Sciences

    Samuel Y. Sheng Professor Kam W Leong

  4. The effect of substrate topography on direct reprogramming of fibroblasts to induced neurons

    Article • Biomaterials, July 2014, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  5. SOD Therapeutics: Latest Insights into Their Structure-Activity Relationships and Impact on the Cellular Redox-Based Signaling Pathways

    Article • Antioxidants & Redox Signaling, May 2014, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  6. Gene Delivery: Nonendocytic Delivery of Lipoplex Nanoparticles into Living Cells Using Nanochannel Electroporation (Adv. Healthcare Mater. 5/2014)

    Article • Advanced Healthcare Materials, May 2014, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  7. Synthesis of Fluorosurfactants for Emulsion-Based Biological Applications

    Article • ACS Nano, March 2014, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong, Hon Fai Chan, Kyle Phua, Yi-Ping Ho

  8. Abstract 166

    Article • Plastic & Reconstructive Surgery, March 2014, Wolters Kluwer Health

    Samuel Y. Sheng Professor Kam W Leong

  9. Hierarchical Patterns: Harnessing Localized Ridges for High‐Aspect‐Ratio Hierarchical Patterns with Dynamic Tunability and Multifunctionality (Adv. Mater. 11/2014)

    Article • Advanced Materials, March 2014, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  10. Highly Aligned Nanofibrous Scaffold Derived from Decellularized Human Fibroblasts

    Article • Advanced Functional Materials, January 2014, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  11. Three-Dimensional Hydrodynamic Focusing Method for Polyplex Synthesis

    Article • ACS Nano, January 2014, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong, Yi-Ping Ho

  12. Magnetoactive sponges for dynamic control of microfluidic flow patterns in microphysiological systems

    Article • Lab on a Chip, January 2014, Royal Society of Chemistry

    Samuel Y. Sheng Professor Kam W Leong, Hon Fai Chan, George Truskey

  13. Messenger RNA (mRNA) nanoparticle tumour vaccination

    Article • Nanoscale, January 2014, Royal Society of Chemistry

    Samuel Y. Sheng Professor Kam W Leong, Kyle Phua

  14. Whole Blood Cells Loaded with Messenger RNA as an Anti‐Tumor Vaccine

    Article • Advanced Healthcare Materials, December 2013, Wiley

    Samuel Y. Sheng Professor Kam W Leong, Kyle Phua

  15. An efficient way to generate localized ridges in nano/micro-range for biological applications

    Article • Advanced Materials, December 2013, Wiley

    Samuel Y. Sheng Professor Kam W Leong, Hon Fai Chan

  16. Rapid formation of spheroids in double-emulsion droplets

    Article • Scientific Reports, December 2013, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong, Hon Fai Chan, Yi-Ping Ho

  17. Design considerations for an integrated microphysiological muscle tissue for drug and tissue toxicity testing

    Article • Stem Cell Research & Therapy, December 2013, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong, Hon Fai Chan

  18. Microfluidic Preparation of Polymer-Nucleic Acid Nanocomplexes Improves Nonviral Gene Transfer

    Article • Scientific Reports, November 2013, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong, Yi-Ping Ho

  19. Temperature-Controlled Encapsulation and Release of an Active Enzyme in the Cavity of a Self-Assembled DNA Nanocage

    Article • ACS Nano, November 2013, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  20. Differentiation of Mouse Induced Pluripotent Stem Cells (iPSCs) into Nucleus Pulposus-Like Cells In Vitro

    Article • PLOS One, September 2013, PLOS

    Samuel Y. Sheng Professor Kam W Leong, Nicolas Christoforou

  21. Nonendocytic Delivery of Lipoplex Nanoparticles into Living Cells Using Nanochannel Electroporation

    Article • Advanced Healthcare Materials, August 2013, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  22. Integration of drug, protein, and gene delivery systems with regenerative medicine

    Article • Drug Delivery and Translational Research, August 2013, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  23. RNA-guided gene activation by CRISPR-Cas9–based transcription factors

    Article • Nature Chemical Biology, July 2013, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  24. Induced Pluripotent Stem Cell-Derived Cardiac Progenitors Differentiate to Cardiomyocytes and Form Biosynthetic Tissues

    Article • PLOS One, June 2013, PLOS

    Samuel Y. Sheng Professor Kam W Leong, Nicolas Christoforou

  25. In vitro and in vivo models for the study of oral delivery of nanoparticles

    Article • Advanced Drug Delivery Reviews, June 2013, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  26. Mechanism of oral tolerance induction to therapeutic proteins

    Article • Advanced Drug Delivery Reviews, June 2013, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  27. Nanoparticle- and biomaterials-mediated oral delivery for drug, gene, and immunotherapy

    Article • Advanced Drug Delivery Reviews, June 2013, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  28. A programmable microenvironment for cellular studies via microfluidics-generated double emulsions

    Article • Biomaterials, June 2013, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Hon Fai Chan, Yi-Ping Ho

  29. A Robust Strategy for Negative Selection of Cre-LoxP Recombination-Based Excision of Transgenes in Induced Pluripotent Stem Cells

    Article • PLOS One, May 2013, PLOS

    Samuel Y. Sheng Professor Kam W Leong, Nicolas Christoforou

  30. Transcription Factors MYOCD, SRF, Mesp1 and SMARCD3 Enhance the Cardio-Inducing Effect of GATA4, TBX5, and MEF2C during Direct Cellular Reprogramming

    Article • PLOS One, May 2013, PLOS

    Samuel Y. Sheng Professor Kam W Leong, Nicolas Christoforou

  31. In vivo mRNA nanoparticle delivery; transfection efficiency & kinetics @ 4 different injection sites

    Article • Journal of Controlled Release, March 2013, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Kyle Phua

  32. Comparison of Mixed and Lamellar Coculture Spatial Arrangements for Tissue Engineering Capillary NetworksIn Vitro

    Article • Tissue Engineering Part A, March 2013, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong, Nicolas Christoforou

  33. Materials innovation for co-delivery of diverse therapeutic cargos

    Article • RSC Advances, January 2013, Royal Society of Chemistry

    Samuel Y. Sheng Professor Kam W Leong, Smruthi Suryaprakash, Megan Godsey

  34. Microfluidic Cell Culture Platforms with Embedded Nanoscale Features

    Article • January 2013, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  35. Advanced materials and processing for drug delivery: The past and the future

    Article • Advanced Drug Delivery Reviews, January 2013, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Hon Fai Chan

  36. Single cell enzyme diagnosis on the chip

    Article • January 2013, Institute of Electrical & Electronics Engineers (IEEE)

    Samuel Y. Sheng Professor Kam W Leong, Yi-Ping Ho

  37. Butterfly Wing–Inspired Nanotechnology

    Article • November 2012, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  38. Droplet Microfluidics Platform for Highly Sensitive and Quantitative Detection of Malaria-Causing Plasmodium Parasites Based on Enzyme Activity Measurement

    Article • ACS Nano, November 2012, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  39. Understanding Differences in Mechanisms of Action of Fe vs Mn Porphyrins: Comparison of Their Reactivities Towards Cellular Reductants and Reactive Species

    Article • Free Radical Biology and Medicine, November 2012, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  40. Guidance of stem cell fate on 2D patterned surfaces

    Article • Biomaterials, October 2012, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  41. Effects of Topographical and Mechanical Property Alterations Induced by Oxygen Plasma Modification on Stem Cell Behavior

    Article • ACS Nano, September 2012, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  42. The Inhibition of Anti-DNA Binding to DNA by Nucleic Acid Binding Polymers

    Article • PLOS One, July 2012, PLOS

    Samuel Y. Sheng Professor Kam W Leong

  43. Nanotopography as modulator of human mesenchymal stem cell function

    Article • Biomaterials, July 2012, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  44. Comparative study of nanoparticle-mediated transfection in different GI epithelium co-culture models

    Article • Journal of Controlled Release, May 2012, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  45. Therapeutic nanorods with metallic multi-segments: Thermally inducible encapsulation of doxorubicin for anti-cancer therapy

    Article • Nano Today, April 2012, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  46. Understanding nonviral nucleic acid delivery with quantum dot-FRET nanosensors

    Article • Nanomedicine, April 2012, Future Medicine

    Samuel Y. Sheng Professor Kam W Leong, Yi-Ping Ho

  47. Near-Infrared Fluorescent Nanoprobes for in Vivo Optical Imaging

    Article • Nanomaterials, March 2012, MDPI AG

    Samuel Y. Sheng Professor Kam W Leong

  48. Synthetic mast-cell granules as adjuvants to promote and polarize immunity in lymph nodes

    Article • Nature Materials, January 2012, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong, Dr Ashley L. St. John

  49. Microfluidic synthesis of multifunctional Janus particles for biomedical applications

    Article • Lab on a Chip, January 2012, Royal Society of Chemistry

    Samuel Y. Sheng Professor Kam W Leong

  50. Nonviral Direct Conversion of Primary Mouse Embryonic Fibroblasts to Neuronal Cells

    Article • Molecular Therapy — Nucleic Acids, January 2012, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  51. Nucleic acid-binding polymers as anti-inflammatory agents: reducing the danger of nuclear attack

    Article • Expert Review of Clinical Immunology, January 2012, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  52. Pluripotent stem cell-derived cardiac tissue patch with advanced structure and function

    Article • Biomaterials, December 2011, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Nicolas Christoforou

  53. Three-dimensional culture of rabbit nucleus pulposus cells in collagen microspheres

    Article • The Spine Journal, October 2011, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  54. Detection of Single Enzymatic Events in Rare or Single Cells Using Microfluidics

    Article • ACS Nano, September 2011, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong, Yi-Ping Ho

  55. Cytotoxic effects of Mn(III)N-alkylpyridylporphyrins in the presence of cellular reductant, ascorbate

    Article • Free Radical Research, September 2011, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong, Dr. Katherine M Aird

  56. Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimics

    Article • Free Radical Biology and Medicine, September 2011, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Professor Ludmil T Benov

  57. Mechanical behavior of human embryonic stem cell pellet under unconfined compression

    Article • Biomechanics and Modeling in Mechanobiology, August 2011, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  58. Uptake and Intracellular Fate of Multifunctional Nanoparticles: A Comparison between Lipoplexes and Polyplexes via Quantum Dot Mediated Förster Resonance Energy Transfer

    Article • Molecular Pharmaceutics, July 2011, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  59. Transient Depletion of Kupffer Cells Leads to Enhanced Transgene Expression in Rat Liver Following Retrograde Intrabiliary Infusion of Plasmid DNA and DNA Nanoparticles

    Article • Human Gene Therapy, July 2011, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  60. Dynamic Topographical Control of Mesenchymal Stem Cells by Culture on Responsive Poly(ϵ‐caprolactone) Surfaces

    Article • Advanced Materials, May 2011, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  61. Tuning Physical Properties of Nanocomplexes through Microfluidics-Assisted Confinement

    Article • Nano Letters, May 2011, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong, Yi-Ping Ho

  62. High-throughput screening of microscale pitted substrate topographies for enhanced nonviral transfection efficiency in primary human fibroblasts

    Article • Biomaterials, May 2011, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Nicolas Christoforou

  63. A 3D Electroactive Polypyrrole-Collagen Fibrous Scaffold for Tissue Engineering

    Article • Polymers, February 2011, MDPI AG

    Samuel Y. Sheng Professor Kam W Leong, Professor Chwee Teck Lim

  64. Efficacy of engineered FVIII-producing skeletal muscle enhanced by growth factor-releasing co-axial electrospun fibers

    Article • Biomaterials, February 2011, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  65. Unexpected properties of polymeric DNA-nanocomplexes synthesized in picoliter droplets

    Article • February 2011, Institute of Electrical & Electronics Engineers (IEEE)

    Samuel Y. Sheng Professor Kam W Leong, Yi-Ping Ho

  66. Simultaneous Delivery of siRNA and Paclitaxel via a “Two-in-One” Micelleplex Promotes Synergistic Tumor Suppression

    Article • ACS Nano, January 2011, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  67. Engineering of a microfluidic cell culture platform embedded with nanoscale features

    Article • Lab on a Chip, January 2011, Royal Society of Chemistry

    Samuel Y. Sheng Professor Kam W Leong

  68. Stem cell differentiation indicated by noninvasive photonic characterization and fractal analysis of subcellular architecture

    Article • Integrative Biology, January 2011, Oxford University Press (OUP)

    Samuel Y. Sheng Professor Kam W Leong

  69. Emerging links between surface nanotechnology and endocytosis: Impact on nonviral gene delivery

    Article • Nano Today, December 2010, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  70. Stem Cells in Cardiac Tissue Engineering

    Article • November 2010, World Scientific Pub Co Pte Lt

    Samuel Y. Sheng Professor Kam W Leong, Nicolas Christoforou

  71. Engineering a Highly Functional 3D Cardiac Tissue Patch From Embryonic Stem Cell-Derived Cardiogenic Cells

    Article • Heart Rhythm, November 2010, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Nicolas Christoforou

  72. Bioavailability of metalloporphyrin-based SOD mimics is greatly influenced by a single charge residing on a Mn site

    Article • Free Radical Research, October 2010, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong, Professor Ludmil T Benov

  73. Implantation of Mouse Embryonic Stem Cell-Derived Cardiac Progenitor Cells Preserves Function of Infarcted Murine Hearts

    Article • PLOS One, July 2010, PLOS

    Samuel Y. Sheng Professor Kam W Leong, Nicolas Christoforou

  74. Chaperoning vaccines

    Article • Nature Materials, July 2010, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  75. Dual‐Sensitive Micellar Nanoparticles Regulate DNA Unpacking and Enhance Gene‐Delivery Efficiency

    Article • Advanced Materials, June 2010, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  76. Characterization of topographical effects on macrophage behavior in a foreign body response model

    Article • Biomaterials, May 2010, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  77. Low Oxygen Tension and Synthetic Nanogratings Improve the Uniformity and Stemness of Human Mesenchymal Stem Cell Layer

    Article • Molecular Therapy, May 2010, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Nicolas Christoforou

  78. Nanoscale surfacing for regenerative medicine

    Article • Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology, April 2010, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  79. Microscale oral delivery devices incorporating nanoparticles

    Article • Nanomedicine, February 2010, Future Medicine

    Samuel Y. Sheng Professor Kam W Leong, Kyle Phua

  80. Nanotopography-induced changes in focal adhesions, cytoskeletal organization, and mechanical properties of human mesenchymal stem cells

    Article • Biomaterials, February 2010, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  81. Electrosprayed core–shell microspheres for protein delivery

    Article • Chemical Communications, January 2010, Royal Society of Chemistry

    Samuel Y. Sheng Professor Kam W Leong

  82. Quantum dot-based theranostics

    Article • Nanoscale, January 2010, Royal Society of Chemistry

    Samuel Y. Sheng Professor Kam W Leong, Yi-Ping Ho

  83. Controlled Synthesis of DNA Nanocomplexes in a Microfluidic Device

    Article • Biophysical Journal, January 2010, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Yi-Ping Ho

  84. Deformation of stem cell nuclei by nanotopographical cues

    Article • Soft Matter, January 2010, Royal Society of Chemistry

    Samuel Y. Sheng Professor Kam W Leong

  85. Transport of chitosan–DNA nanoparticles in human intestinal M-cell model versus normal intestinal enterocytes

    Article • European Journal of Pharmaceutical Sciences, January 2010, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  86. Electrohydrodynamics: A facile technique to fabricate drug delivery systems

    Article • Advanced Drug Delivery Reviews, October 2009, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  87. Sustained viral gene delivery through core-shell fibers

    Article • Journal of Controlled Release, October 2009, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  88. Development of universal antidotes to control aptamer activity

    Article • Nature Medicine, October 2009, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  89. Combining QD-FRET and Microfluidics to Monitor DNA Nanocomplex Self-Assembly in Real-Time

    Article • Journal of Visualized Experiments, August 2009, MyJove Corporation

    Samuel Y. Sheng Professor Kam W Leong, Yi-Ping Ho

  90. Simultaneous non-invasive analysis of DNA condensation and stability by two-step QD-FRET

    Article • Nano Today, April 2009, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  91. The convergence of quantum-dot-mediated fluorescence resonance energy transfer and microfluidics for monitoring DNA polyplex self-assembly in real time

    Article • Nanotechnology, February 2009, Institute of Physics Publishing

    Samuel Y. Sheng Professor Kam W Leong

  92. Spatially-resolved Analysis Of DNA Nanocomplex Self-assembly Enabled By Integrating Nanophotonics And Microfluidics

    Article • Biophysical Journal, February 2009, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Yi-Ping Ho

  93. Light Scattering Detects Changes In Subcellular Structure And Organization With Connections To Cell Function

    Article • Biophysical Journal, February 2009, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  94. Substrate topography shapes cell function

    Article • Soft Matter, January 2009, Royal Society of Chemistry

    Samuel Y. Sheng Professor Kam W Leong

  95. Synthesis and Cytotoxicity of Luminescent InP Quantum Dots

    Article • MRS Proceedings, January 2009, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  96. Gene transfer to hemophilia A mice via oral delivery of FVIII–chitosan nanoparticles

    Article • Journal of Controlled Release, December 2008, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  97. Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium

    Article • Nanomedicine Nanotechnology Biology and Medicine, December 2008, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  98. Gene Delivery via Polymer Nanoparticles

    Article • November 2008, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  99. Effect of Electromechanical Stimulation on the Maturation of Myotubes on Aligned Electrospun Fibers

    Article • Cellular and Molecular Bioengineering, September 2008, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  100. Viscoelastic behaviour of human mesenchymal stem cells

    Article • BMC Cell Biology, July 2008, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  101. Radiation-Inducible Caspase-8 Gene Therapy for Malignant Brain Tumors

    Article • International Journal of Radiation Oncology*Biology*Physics, June 2008, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  102. Label-Free, High-Throughput Measurements of Dynamic Changes in Cell Nuclei Using Angle-Resolved Low Coherence Interferometry

    Article • Biophysical Journal, June 2008, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  103. Poly(ethylene imine)‐g‐chitosan using EX‐810 as a spacer for nonviral gene delivery vectors

    Article • Journal of Biomedical Materials Research Part A, April 2008, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  104. In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF)

    Article • Biomaterials, February 2008, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  105. The effect of the alignment of electrospun fibrous scaffolds on Schwann cell maturation

    Article • Biomaterials, February 2008, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  106. Quantitative Comparison of Intracellular Unpacking Kinetics of Polyplexes by a Model Constructed From Quantum Dot-FRET

    Article • Molecular Therapy, February 2008, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  107. Engineering strategies to enhance nanoparticle-mediated oral delivery

    Article • Journal of Biomaterials Science Polymer Edition, January 2008, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  108. Quantitative kinetic analysis of DNA nanocomplex self-assembly with Quantum Dots FRET in a microfluidic device

    Article • January 2008, Institute of Electrical & Electronics Engineers (IEEE)

    Samuel Y. Sheng Professor Kam W Leong

  109. Novel anisotropic engineered cardiac tissues: Studies of electrical propagation

    Article • Biochemical and Biophysical Research Communications, October 2007, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  110. A dual-functional fibrous scaffold enhances P450 activity of cultured primary rat hepatocytes

    Article • Acta Biomaterialia, September 2007, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  111. Tissue‐Engineered Bone Formation With Gene Transfer and Mesenchymal Stem Cells in a Minimally Invasive Technique

    Article • The Laryngoscope, July 2007, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  112. Tracheal Tissue Engineering

    Article • May 2007, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  113. Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage

    Article • Experimental Cell Research, May 2007, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  114. Effects of MIP-1α, MIP-3α, and MIP-3β on the Induction of HIV Gag-specific Immune Response with DNA Vaccines

    Article • Molecular Therapy, May 2007, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  115. Functional nanofiber scaffolds with different spacers modulate adhesion and expansion of cryopreserved umbilical cord blood hematopoietic stem/progenitor cells

    Article • Experimental Hematology, May 2007, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  116. In Vitro Chondrogenesis of Mesenchymal Stem Cells in Recombinant Silk-elastinlike Hydrogels

    Article • Pharmaceutical Research, April 2007, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  117. Biomaterials Approach to Expand and Direct Differentiation of Stem Cells

    Article • Molecular Therapy, March 2007, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  118. Dynamics of smooth muscle cell deadhesion from thermosensitive hydroxybutyl chitosan

    Article • Biomaterials, March 2007, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  119. Fibronectin immobilized by covalent conjugation or physical adsorption shows different bioactivity on aminated-PET

    Article • Materials Science and Engineering C, March 2007, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  120. Tissue Compatibility of Interfacial Polyelectrolyte Complexation Fibrous Scaffold: Evaluation of Blood Compatibility and Biocompatibility

    Article • Tissue Engineering, February 2007, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  121. Designing Zonal Organization into Tissue-Engineered Cartilage

    Article • Tissue Engineering, February 2007, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  122. Radio-responsive gene therapy for malignant glioma cells without the radiosensitive promoter: Caspase-3 gene therapy combined with radiation

    Article • Cancer Letters, February 2007, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  123. Designing Zonal Organization into Tissue-Engineered Cartilage

    Article • Tissue Engineering, December 2006, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  124. Tissue Compatibility of Interfacial Polyelectrolyte Complexation Fibrous Scaffold: Evaluation of Blood Compatibility and Biocompatibility

    Article • Tissue Engineering, December 2006, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  125. Hepatic Differentiation Potential of Commercially Available Human Mesenchymal Stem Cells

    Article • Tissue Engineering, December 2006, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  126. Proliferation and differentiation of human mesenchymal stem cell encapsulated in polyelectrolyte complexation fibrous scaffold

    Article • Biomaterials, December 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  127. Chitosan-DNA nanoparticles delivered by intrabiliary infusion enhance liver-targeted gene delivery

    Article • International Journal of Nanomedicine, December 2006, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  128. Surface-aminated electrospun nanofibers enhance adhesion and expansion of human umbilical cord blood hematopoietic stem/progenitor cells

    Article • Biomaterials, December 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  129. Evaluating the intracellular stability and unpacking of DNA nanocomplexes by quantum dots-FRET

    Article • Journal of Controlled Release, November 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Yi-Ping Ho

  130. Hepatic Differentiation Potential of Commercially Available Human Mesenchymal Stem Cells

    Article • Tissue Engineering, October 2006, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  131. Small Intestinal Submucosa as a Potential Bioscaffold for Intervertebral Disc Regeneration

    Article • Spine, October 2006, Wolters Kluwer Health

    Samuel Y. Sheng Professor Kam W Leong

  132. In Vivo Evaluation of Plasmid DNA Encoding OP-1 Protein for Spine Fusion

    Article • Spine, September 2006, Wolters Kluwer Health

    Samuel Y. Sheng Professor Kam W Leong

  133. Inducing hepatic differentiation of human mesenchymal stem cells in pellet culture

    Article • Biomaterials, August 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  134. Co-culture of Umbilical Cord Blood CD34þ Cells with Human Mesenchymal Stem Cells

    Article • Tissue Engineering, August 2006, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  135. Interaction of Human Mesenchymal Stem Cells With Disc Cells

    Article • Spine, August 2006, Wolters Kluwer Health

    Samuel Y. Sheng Professor Kam W Leong

  136. Self-assembled supramolecular hydrogels formed by biodegradable PEO–PHB–PEO triblock copolymers and α-cyclodextrin for controlled drug delivery

    Article • Biomaterials, August 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  137. Mechanical properties of single electrospun drug-encapsulated nanofibres

    Article • Nanotechnology, July 2006, Institute of Physics Publishing

    Samuel Y. Sheng Professor Kam W Leong, Professor Chwee Teck Lim

  138. Enhanced extracellular matrix production and differentiation of human embryonic germ cell derivatives in biodegradable poly(ε-caprolactone-co-ethyl ethylene phosphate) scaffold

    Article • Acta Biomaterialia, July 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  139. Co-culture of Umbilical Cord Blood CD34 + Cells with Human Mesenchymal Stem Cells

    Article • Tissue Engineering, June 2006, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  140. Quantum-dots-FRET nanosensors for detecting unamplified nucleic acids by single molecule detection

    Article • Nanomedicine, June 2006, Future Medicine

    Samuel Y. Sheng Professor Kam W Leong

  141. Enhancing Efficacy of HIV Gag DNA Vaccine by Local Delivery of GM-CSF in Murine and Macaque Models

    Article • Journal of Interferon & Cytokine Research, June 2006, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  142. A75. Nanoparticles: Novel cardioprotective devices that utilize a preconditioning-like mechanism

    Article • Journal of Molecular and Cellular Cardiology, June 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  143. Expansion of engrafting human hematopoietic stem/progenitor cells in three‐dimensional scaffolds with surface‐immobilized fibronectin

    Article • Journal of Biomedical Materials Research Part A, May 2006, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  144. Tracheal Tissue Engineering

    Article • May 2006, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  145. Hyperbranched Poly(amino ester)s with Different Terminal Amine Groups for DNA Delivery

    Article • Biomacromolecules, April 2006, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  146. Biodegradable and photocrosslinkable polyphosphoester hydrogel

    Article • Biomaterials, March 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  147. Controlled release of heparin from poly(ε-caprolactone) electrospun fibers

    Article • Biomaterials, March 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  148. Dynamic and Static Light Scattering Studies on Self-Aggregation Behavior of Biodegradable Amphiphilic Poly(ethylene oxide)−Poly[(R)-3-hydroxybutyrate]−Poly(ethylene oxide) Triblock Copolymers in Aqueous Solution

    Article • The Journal of Physical Chemistry B, March 2006, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  149. Chitosan‐g‐PEG/DNA complexes deliver gene to the rat liver via intrabiliary and intraportal infusions

    Article • The Journal of Gene Medicine, January 2006, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  150. 167. Polyethyleneimines as Vehicles for Oral Gene Delivery

    Article • Molecular Therapy, January 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  151. 402. Intracellular Trafficking of QD-FRET Nanoparticles for Gene Delivery

    Article • Molecular Therapy, January 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  152. 171. PEG-b-PPA/DNA Micelles for Liver Targeted-Gene Delivery

    Article • Molecular Therapy, January 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  153. 356. Engineering of Cell Surface Sialic Acids for Polymeric Gene Delivery

    Article • Molecular Therapy, January 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  154. Chitosan nanoparticles for oral drug and gene delivery

    Article • International Journal of Nanomedicine, January 2006, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  155. Temperature-responsive hydroxybutyl chitosan for the culture of mesenchymal stem cells and intervertebral disk cells

    Article • Biomaterials, January 2006, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  156. PEI-g-chitosan, a Novel Gene Delivery System with Transfection Efficiency Comparable to Polyethylenimine in Vitro and after Liver Administration in Vivo

    Article • Bioconjugate Chemistry, December 2005, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  157. Galactosylated Poly(vinylidene difluoride) Hollow Fiber Bioreactor for Hepatocyte Culture

    Article • Tissue Engineering, November 2005, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  158. Evaluation of Hyperbranched Poly(amino ester)s of Amine Constitutions Similar to Polyethylenimine for DNA Delivery

    Article • Biomacromolecules, October 2005, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  159. Polymeric Controlled Nucleic Acid Delivery

    Article • MRS Bulletin, September 2005, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  160. Engineering microenvironment for expansion of sensitive anchorage-dependent mammalian cells

    Article • Journal of Biotechnology, September 2005, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  161. Polymeric Scaffolds for Gene Delivery and Regenerative Medicine

    Article • August 2005, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  162. Micellization Phenomena of Biodegradable Amphiphilic Triblock Copolymers Consisting of Poly(β-hydroxyalkanoic acid) and Poly(ethylene oxide)

    Article • Langmuir, August 2005, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong, Professor Chwee Teck Lim

  163. Targeted Tumor Cell Death Induced by Autologous Tumor-Specific T Lymphocyte Recognition of Wild-Type p53-Derived Peptides

    Article • Journal of Neuro-Oncology, July 2005, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  164. Polyethylenimine‐Grafted Multiwalled Carbon Nanotubes for Secure Noncovalent Immobilization and Efficient Delivery of DNA

    Article • Angewandte Chemie, July 2005, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  165. Polyethylenimine‐Grafted Multiwalled Carbon Nanotubes for Secure Noncovalent Immobilization and Efficient Delivery of DNA

    Article • Angewandte Chemie, July 2005, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  166. 5:4949. Small intestinal submucosa for nucleus pulposus augmentation: a feasibility study in rabbits

    Article • The Spine Journal, July 2005, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  167. Three-dimensional co-culture of rat hepatocyte spheroids and NIH/3T3 fibroblasts enhances hepatocyte functional maintenance

    Article • Acta Biomaterialia, July 2005, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  168. Sustained Release of Proteins from Electrospun Biodegradable Fibers

    Article • Biomacromolecules, May 2005, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  169. Controlled release from fibers of polyelectrolyte complexes

    Article • Journal of Controlled Release, May 2005, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  170. Stable immobilization of rat hepatocyte spheroids on galactosylated nanofiber scaffold

    Article • Biomaterials, May 2005, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  171. pH responsive adhesion of phospholipid vesicle on poly(acrylic acid) cushion grafted to poly(ethylene terephthalate) surface

    Article • Colloids and Surfaces B Biointerfaces, May 2005, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  172. Significance of synthetic nanostructures in dictating cellular response

    Article • Nanomedicine Nanotechnology Biology and Medicine, March 2005, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  173. Adhesion contact dynamics of primary hepatocytes on poly(ethylene terephthalate) surface

    Article • Biomaterials, March 2005, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  174. MR imaging of biodegradable polymeric microparticles: A potential method of monitoring local drug delivery

    Article • Magnetic Resonance in Medicine, February 2005, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  175. Galactosylated ternary DNA/polyphosphoramidate nanoparticles mediate high gene transfection efficiency in hepatocytes

    Article • Journal of Controlled Release, February 2005, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  176. Proliferation and differentiation of human embryonic germ cell derivatives in bioactive polymeric fibrous scaffold

    Article • Journal of Biomaterials Science Polymer Edition, January 2005, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  177. Musculoskeletal Differentiation of Cells Derived from Human Embryonic Germ Cells

    Article • Stem Cells, January 2005, Oxford University Press (OUP)

    Samuel Y. Sheng Professor Kam W Leong

  178. Design of Polyphosphoester‐DNA Nanoparticles for Non‐Viral Gene Delivery

    Article • January 2005, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  179. Biodegradable poly(terephthalate-co-phosphate)s: synthesis, characterization and drug-release properties

    Article • Journal of Biomaterials Science Polymer Edition, January 2005, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  180. Ternary Complexes Comprising Polyphosphoramidate Gene Carriers with Different Types of Charge Groups Improve Transfection Efficiency

    Article • Biomacromolecules, December 2004, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  181. In Vitro Gene Delivery Using Polyamidoamine Dendrimers with a Trimesyl Core

    Article • Biomacromolecules, December 2004, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  182. Encapsulation of biologics in self‐assembled fibers as biostructural units for tissue engineering

    Article • Journal of Biomedical Materials Research Part A, October 2004, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  183. The effect of the degree of chitosan deacetylation on the efficiency of gene transfection

    Article • Biomaterials, October 2004, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  184. Coculture of Mesenchymal Stem Cells and Respiratory Epithelial Cells to Engineer a Human Composite Respiratory Mucosa

    Article • Tissue Engineering, September 2004, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  185. Role of intermolecular interaction between hydrophobic blocks in block-selected inclusion complexation of amphiphilic poly(ethylene oxide)-poly[(R)-3-hydroxybutyrate]-poly(ethylene oxide) triblock copolymers with cyclodextrins

    Article • Polymer, September 2004, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  186. 127. Small intestinal submucosa (SIS) as a potential bioscaffold for intervertebral disc regeneration

    Article • The Spine Journal, September 2004, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  187. Coculture of Mesenchymal Stem Cells and Respiratory Epithelial Cells to Engineer a Human Composite Respiratory Mucosa

    Article • Tissue Engineering, September 2004, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  188. Mechanism of Fiber Formation by Interfacial Polyelectrolyte Complexation

    Article • Macromolecules, August 2004, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  189. Bioadhesive characterization of poly(methylidene malonate 2.12) microparticle on model extracellular matrix

    Article • Biomaterials, August 2004, Elsevier

    Samuel Y. Sheng Professor Kam W Leong, Dr Isaac LIU

  190. Biodegradable polyphosphoester micelles for gene delivery

    Article • Journal of Pharmaceutical Sciences, August 2004, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  191. Photo-crosslinkable microcapsules formed by polyelectrolyte copolymer and modified collagen for rat hepatocyte encapsulation

    Article • Biomaterials, August 2004, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  192. Evaluation of collagen and methylated collagen as gene carriers

    Article • International Journal of Pharmaceutics, July 2004, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  193. Block‐Selected Molecular Recognition and Formation of Polypseudorotaxanes between Poly(propylene oxide)‐Poly(ethylene oxide)‐Poly(propylene oxide) Triblock Copolymers and α‐Cyclodextrin

    Article • Angewandte Chemie, June 2004, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  194. Block‐Selected Molecular Recognition and Formation of Polypseudorotaxanes between Poly(propylene oxide)‐Poly(ethylene oxide)‐Poly(propylene oxide) Triblock Copolymers and α‐Cyclodextrin

    Article • Angewandte Chemie, June 2004, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  195. In vitro release of vascular endothelial growth factor from gadolinium‐doped biodegradable microspheres

    Article • Magnetic Resonance in Medicine, May 2004, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  196. Directed Assembly of Multisegment Au/Pt/Au Nanowires

    Article • Nano Letters, May 2004, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  197. Polyelectrolyte Complex Films Derived from Polyethyleneoxide‐Maleic Acid Copolymer and Chitosan: Preparation and Characterization

    Article • Macromolecular Bioscience, May 2004, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  198. Polymer Nanoparticles for Gene Delivery

    Article • March 2004, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  199. Poly(phosphoester) ionomers as tissue‐engineering scaffolds

    Article • Journal of Biomedical Materials Research Part B Applied Biomaterials, March 2004, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  200. Photoregulated Sol‐Gel Transition of Novel Azobenzene‐Functionalized Hydroxypropyl Methylcellulose and Its α‐Cyclodextrin Complexes

    Article • Macromolecular Rapid Communications, March 2004, Wiley

    Samuel Y. Sheng Professor Kam W Leong, Professor Kam Chiu Tam

  201. Efficacy of Paclitaxel Released From Bio-Adhesive Polymer Microspheres on Model Superficial Bladder Cancer

    Article • The Journal of Urology, March 2004, Wolters Kluwer Health

    Samuel Y. Sheng Professor Kam W Leong

  202. Water-Soluble and Nonionic Polyphosphoester:  Synthesis, Degradation, Biocompatibility and Enhancement of Gene Expression in Mouse Muscle

    Article • Biomacromolecules, February 2004, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  203. A Nonlinear Hyperelastic Mixture Theory Model for Anisotropy, Transport, and Swelling of Annulus Fibrosus

    Article • Annals of Biomedical Engineering, January 2004, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  204. Formulation of chitosan-DNA nanoparticles with poly(propyl acrylic acid) enhances gene expression

    Article • Journal of Biomaterials Science Polymer Edition, January 2004, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  205. Stimuli-Responsive Hydrogel Based on Poly(propylene phosphate)

    Article • Macromolecules, December 2003, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  206. Peripheral nerve regeneration by microbraided poly(L‐lactide‐co‐glycolide) biodegradable polymer fibers

    Article • Journal of Biomedical Materials Research Part A, December 2003, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  207. Fixed-tumor vaccine: A practical formulation with cytokine-microspheres for protective and therapeutic antitumor immunity

    Article • The Chinese-German Journal of Clinical Oncology, December 2003, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  208. Galactosylated PVDF membrane promotes hepatocyte attachment and functional maintenance

    Article • Biomaterials, December 2003, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  209. Photocrosslinkable polysaccharides based on chondroitin sulfate

    Article • Journal of Biomedical Materials Research Part A, November 2003, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  210. High density of immobilized galactose ligand enhances hepatocyte attachment and function

    Article • Journal of Biomedical Materials Research Part A, October 2003, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  211. Effect of side-chain structures on gene transfer efficiency of biodegradable cationic polyphosphoesters

    Article • International Journal of Pharmaceutics, October 2003, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  212. Thermally responsive polymeric micellar nanoparticles self-assembled from cholesteryl end-capped random poly(N-isopropylacrylamide-co-N,N-dimethylacrylamide): synthesis, temperature-sensitivity, and morphologies

    Article • Journal of Colloid and Interface Science, October 2003, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  213. Multifunctional nanorods for gene delivery

    Article • Nature Materials, September 2003, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  214. Poly(d,llactide–co-ethyl ethylene phosphate)s as new drug carriers

    Article • Journal of Controlled Release, September 2003, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  215. Use of Ultrathin Shell Microcapsules of Hepatocytes in Bioartificial Liver-Assist Device

    Article • Tissue Engineering, August 2003, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  216. In Vivo US Monitoring of Catheter-based Vascular Delivery of Gene Microspheres in Pigs: Feasibility1

    Article • Radiology, August 2003, Radiological Society of North America (RSNA)

    Samuel Y. Sheng Professor Kam W Leong

  217. Controlled/living polymerization of 2‐(diethylamino)ethyl methacrylate and its block copolymer with tert‐butyl methacrylate by atom transfer radical polymerization

    Article • Journal of Polymer Science Part A Polymer Chemistry, July 2003, Wiley

    Samuel Y. Sheng Professor Kam W Leong, Professor Kam Chiu Tam

  218. BHEM-Chol/DOPE liposome induced perturbation of phospholipid bilayer

    Article • Colloids and Surfaces B Biointerfaces, June 2003, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  219. Peripheral nerve regeneration with sustained release of poly(phosphoester) microencapsulated nerve growth factor within nerve guide conduits

    Article • Biomaterials, June 2003, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  220. Microcapsules with improved mechanical stability for hepatocyte culture

    Article • Biomaterials, May 2003, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  221. Polyphosphoesters in drug and gene delivery

    Article • Advanced Drug Delivery Reviews, April 2003, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  222. Synthesis and Characterization of New Biodegradable Amphiphilic Poly(ethylene oxide)-b-poly[(R)-3-hydroxy butyrate]-b-poly(ethylene oxide) Triblock Copolymers

    Article • Macromolecules, March 2003, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  223. Injectable drug‐delivery systems based on supramolecular hydrogels formed by poly(ethylene oxide)s and α‐cyclodextrin

    Article • Journal of Biomedical Materials Research Part A, March 2003, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  224. Preparation and Characterization of Polypseudorotaxanes Based on Block-Selected Inclusion Complexation between Poly(propylene oxide)-Poly(ethylene oxide)-Poly(propylene oxide) Triblock Copolymers and α-Cyclodextrin

    Article • Journal of the American Chemical Society, January 2003, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  225. Preparation and Characterization of Inclusion Complexes of Biodegradable Amphiphilic Poly(ethylene oxide)−Poly[(R)-3-hydroxybutyrate]−Poly(ethylene oxide) Triblock Copolymers with Cyclodextrins

    Article • Macromolecules, January 2003, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  226. Block‐Selected Molecular Recognition and Formation of Polypseudorotaxanes between Poly(propylene oxide)‐Poly(ethylene oxide)‐Poly(propylene oxide) Triblock Copolymers and α‐Cyclodextrin

    Article • Angewandte Chemie, January 2003, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  227. Polymeric Scaffolds for Tissue Engineering

    Article • January 2003, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  228. Spinal Fusion by Percutaneous OP-1 Gene Delivery

    Article • Journal of Korean Society of Spine Surgery, January 2003, Korean Society of Spine Surgery (KAMJE)

    Samuel Y. Sheng Professor Kam W Leong

  229. Comparative Study of Disc Degeneration According to the Annulotomy Methodology: In Vivo Animal Study

    Article • Journal of Korean Society of Spine Surgery, January 2003, Korean Society of Spine Surgery (KAMJE)

    Samuel Y. Sheng Professor Kam W Leong

  230. Polyphosphoester microspheres for sustained release of biologically active nerve growth factor

    Article • Biomaterials, September 2002, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  231. Interaction of human mescenchymal stem cells with disc cells

    Article • The Spine Journal, September 2002, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  232. New polyphosphoramidate with a spermidine side chain as a gene carrier

    Article • Journal of Controlled Release, September 2002, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  233. Intranasal Gene Transfer by Chitosan–DNA Nanospheres Protects BALB/c Mice Against Acute Respiratory Syncytial Virus Infection

    Article • Human Gene Therapy, August 2002, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  234. Colloidal adhesion of phospholipid vesicles: high-resolution reflection interference contrast microscopy and theory

    Article • Colloids and Surfaces B Biointerfaces, August 2002, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  235. Autologous Fixed Tumor Vaccine: A Formulation with Cytokine‐microparticles for Protective Immunity against Recurrence of Human Hepatocellular Carcinoma

    Article • Japanese Journal of Cancer Research, April 2002, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  236. Inclusion Complexation and Formation of Polypseudorotaxanes between Poly[(ethylene oxide)-ran-(propylene oxide)] and Cyclodextrins

    Article • Macromolecules, November 2001, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  237. Interactions of Phospholipid Bilayer with Chitosan:  Effect of Molecular Weight and pH

    Article • Biomacromolecules, September 2001, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  238. Formation of Supramolecular Hydrogels Induced by Inclusion Complexation between Pluronics and α-Cyclodextrin

    Article • Macromolecules, September 2001, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  239. A Novel Biodegradable Gene Carrier Based on Polyphosphoester

    Article • Journal of the American Chemical Society, September 2001, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  240. Biomedical applications of polymer-composite materials: a review

    Article • Composites Science and Technology, July 2001, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  241. Chitosan-Induced Perturbation of Dipalmitoyl-sn-glycero-3-phosphocholine Membrane Bilayer

    Article • Langmuir, May 2001, American Chemical Society (ACS)

    Samuel Y. Sheng Professor Kam W Leong

  242. Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency

    Article • Journal of Controlled Release, February 2001, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  243. Hepatocyte Encapsulation for Enhanced Cellular Functions

    Article • Tissue Engineering, October 2000, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  244. Antigen-Specific Induction of Peripheral T Cell Tolerance in Vivo by Codelivery of DNA Vectors Encoding Antigen and Fas Ligand

    Article • Human Gene Therapy, April 2000, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  245. IMPROVEMENT OF DNA IMMUNIZATION EFFICACY WITH GM-CSF CONTROLLED RELEASE SYSTEM

    Article • JAIDS Journal of Acquired Immune Deficiency Syndromes, May 1999, Wolters Kluwer Health

    Samuel Y. Sheng Professor Kam W Leong

  246. Coacervate microspheres as carriers of recombinant adenoviruses

    Article • Cancer Gene Therapy, March 1999, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  247. Biopolymer—DNA Nanospheres

    Article • January 1999, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  248. Gene Transfer by DNA–Gelatin Nanospheres

    Article • Archives of Biochemistry and Biophysics, January 1999, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  249. Controlled Gene Delivery by DNA–Gelatin Nanospheres

    Article • Human Gene Therapy, August 1998, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  250. Drug Delivery Related to Tissue Engineering

    Article • January 1997, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  251. INTERSTITIAL IMMUNOTHERAPY WITH INTERLEUKIN-2 INHIBITS ITS GROWTH AND RECURRENCE OF BRAIN METASTASES

    Article • Southern Medical Journal, October 1996, Southern Medical Association

    Samuel Y. Sheng Professor Kam W Leong

  252. In vitro and in vivo studies of subcutaneous hydromorphone implants designed for the treatment of cancer pain

    Article • Pain, May 1996, Wolters Kluwer Health

    Samuel Y. Sheng Professor Kam W Leong

  253. The Use of Bioerodible Polymers and Daunorubicin in Glaucoma Filtration Surgery

    Article • Ophthalmology, May 1996, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  254. Microcapsules obtained from complex coacervation of collagen and chondroitin sulfate

    Article • Journal of Biomaterials Science Polymer Edition, January 1996, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  255. Engineering of a sugar-derivatized porous network for hepatocyte culture

    Article • Biomaterials, January 1996, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  256. Enzymatically Degradable Synthetic Polymers

    Article • MRS Proceedings, January 1995, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  257. Alternative Materials for Fracture Fixation

    Article • Connective Tissue Research, January 1995, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  258. Targeted delivery of immunomicrospheresin vivo

    Article • Drug Delivery, January 1995, Taylor & Francis

    Samuel Y. Sheng Professor Kam W Leong

  259. The Sustained Release of Galardin and Taxol from Gelatin Chondroitin Sulfate Coacervate Films

    Article • MRS Proceedings, January 1995, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  260. Development of bioabsorbable glass fibres

    Article • Biomaterials, October 1994, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  261. Pharmacokinetics of Etoposide Delivery by a Bioerodible Drug Carrier Implanted at Glaucoma Surgery

    Article • Journal of Ocular Pharmacology and Therapeutics, January 1994, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  262. Synthesis and Characterization of Polymer Substrates for Rat H Epatocyte Culture

    Article • MRS Proceedings, January 1993, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  263. Controlled Drug Delivery to the Joints by Enzymatically Degradable Microspheres

    Article • MRS Proceedings, January 1993, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  264. The use of magnetic resonance imaging to track controlled drug release and transport in the brain

    Article • Magnetic Resonance Imaging, January 1993, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  265. Effects of Cy to sine Arabino side-Impregnated Bioerodible Polymers on Glaucoma Filtration Surgery in Rabbits

    Article • Journal of Glaucoma, January 1993, Wolters Kluwer Health

    Samuel Y. Sheng Professor Kam W Leong

  266. Sustained release of papaverine for the treatment of cerebral vasospasm: in vitro evaluation of release kinetics and biological activity

    Article • November 1992, Journal of Neurosurgery Publishing Group (JNSPG)

    Samuel Y. Sheng Professor Kam W Leong

  267. Improvements in Solubility and Stability of Thalidomide upon Complexation with Hydroxypropyl-β-Cyclodextrin

    Article • Journal of Pharmaceutical Sciences, July 1992, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  268. Fibroblast and hepatocyte behavior on synthetic polymer surfaces

    Article • Journal of Biomedical Materials Research, June 1991, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  269. Llse of Bioerodible Polymers Impregnated with Mitomycin in Glaucoma Filtration Surgery in Rabbits

    Article • Ophthalmology, April 1991, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  270. Growth inhibition of the 9L glioma using polymers to release heparin and cortisone acetate

    Article • Journal of Neuro-Oncology, October 1990, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  271. Biocompatibility of a Biodegradable, Controlled-Release Polymer in the Rabbit Brain

    Article • Selective Cancer Therapeutics, January 1989, Mary Ann Liebert Inc

    Samuel Y. Sheng Professor Kam W Leong

  272. Glaucoma Filtration Surgery in Rabbits Using Bioerodible Polymers and 5-Fluorouracil

    Article • Ophthalmology, December 1987, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  273. Ultrasonic Modulated Drug Delivery Systems

    Article • January 1986, Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong

  274. Controlled Release and Magnetically Modulated Systems for Macromolecular Drugs

    Article • Annals of the New York Academy of Sciences, June 1985, Wiley

    Samuel Y. Sheng Professor Kam W Leong

  275. 71. Vapor-phase intercalation by alcl3-hcl mixtures

    Article • Carbon, January 1982, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  276. 93. Intercalation of graphite with the adducts of nitrosyl chloride and metal chlorides

    Article • Carbon, January 1982, Elsevier

    Samuel Y. Sheng Professor Kam W Leong

  277. Polymer Design for Nonviral Gene Delivery

    Article • Springer Science + Business Media

    Samuel Y. Sheng Professor Kam W Leong