Germania Elizabeth Yugcha Andino

By María Fernanda Calderón León, María Eugenia Ugarte Vega, Germania Elizabeth Yugcha Andino, Paula Andrea Vásquez Jaramillo, Germán Arturo Vélez Sáenz, Joel Paul Vargas Caicedo, Moraima Elizabeth Pazmiño Iñiga, Alfredo Guillermo Chong Viteri, Angélica María Apolo Montero and Nataly del Carmen Quisiguiña Jarrín

Cervical cancer during pregnancy is the most commonly detected malignant tumor. It has become a public health problem, 99% related to human papillomavirus (HPV) infection, making it the only gynecological malignant tumor of clear etiology in the world. It is diagnosed at any stage of pregnancy. Its initial presentation is observed as transvaginal bleeding in all three trimesters associated with HPV infection. If the metastasis is negative in the lymph nodes, it improves. At an early stage the prognosis is favorable, management consists of preserving pregnancy, neoadjuvant chemotherapy can be used to treat cervical cancer in pregnancy, in cases of viable pregnancies between 27- and 31-weeks’ gestation chemotherapy may be performed depending on the staging, caesarean section at 35 weeks, radical surgery and systemic chemotherapy may achieve good results depending on the stage of the tumor.

Part of the book: Women's Health Updates

By Germania Elizabeth Yugcha Andino, María Fernanda Calderón León, Genesis Cecilia Villamar Flores, Luis Antonio Luna Tarira, Ketty Yahaira Mosquera Quiñonez, Doris Sherlene Domo Tomalá, Ángel Gabriel Chango Ramírez, Edison Mauricio Venegas Guijarro, Dennys Fabián Vera Alay, Andrea Alexandra Saltos Román, Karen Xiomara Cortez Salvatierra and Javier Aquiles Hidalgo Acosta

The risk of endometritis and puerperal fever can be decreased by reducing the upward infection of the vaginal bacterial load, even in patients with ruptured membranes. The use of prophylactic antibiotic treatment for puerperal sepsis remains under investigation. Sepsis during pregnancy and the postpartum period accounts for 11% of maternal deaths and ranks third globally. Its global incidence has been increasing, in countries with a maternal mortality rate of 8%, and is caused by multisystem dysregulation resulting from an infection, which can develop during pregnancy, abortion, childbirth, or in the postpartum period and is considered an obstetric emergency. Sepsis is a state of multisystem dysfunction, which is caused by a dysregulated host response to infection. Several factors influence the severity, clinical manifestations, and progression of sepsis, such as immunological heterogeneity, cell signaling pathways, and dynamic regulation of cell signaling pathways.

Part of the book: Postpartum Period for Mother and Newborn