| Entry |
|
|---|
| Name |
Chlorphenoxamine (INN) |
|---|
| Formula |
C18H22ClNO
|
|---|
| Exact mass |
303.1390
|
|---|
| Mol weight |
303.82
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Comment |
Diphenhydramine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07212 | Histamine H1 receptor antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
D04AA Antihistamines for topical use
D04AA34 Chlorphenoxamine
D07198 Chlorphenoxamine (INN)
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AA Aminoalkyl ethers
R06AA06 Chlorphenoxamine
D07198 Chlorphenoxamine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00391 Chlorphenoxamine
D07198 Chlorphenoxamine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D07198 Chlorphenoxamine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG00391 Chlorphenoxamine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 21
1 C8x C 15.2600 -23.6600
2 C8y C 15.2600 -25.0600
3 C8x C 16.4724 -25.7600
4 C8x C 17.6849 -25.0600
5 C8y C 17.6849 -23.6600
6 C8x C 16.4724 -22.9600
7 C1d C 18.9160 -22.9490
8 C8y C 20.1212 -23.6447
9 C8x C 20.1216 -25.0596
10 C8x C 21.3342 -25.7593
11 C8x C 22.5465 -25.0589
12 C8x C 22.5460 -23.6439
13 C8x C 21.3334 -22.9443
14 O2a O 18.9157 -21.5601
15 C1b C 20.1162 -20.8666
16 C1b C 21.3062 -21.5535
17 N1c N 22.4960 -20.8662
18 C1a C 23.6863 -21.5532
19 C1a C 22.4959 -19.4602
20 C1a C 17.7036 -22.2490
21 X Cl 14.0476 -25.7600
BOND 22
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 5 7 1
8 7 8 1
9 8 9 2
10 9 10 1
11 10 11 2
12 11 12 1
13 12 13 2
14 8 13 1
15 7 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 17 19 1
21 7 20 1
22 2 21 1
|
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