Tupaia chinensis (Chinese tree shrew): 102492665
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Entry
102492665 CDS
T02978
Symbol
ALK
Name
(RefSeq) ALK tyrosine kinase receptor
KO
K05119
anaplastic lymphoma kinase [EC:
2.7.10.1
]
Organism
tup
Tupaia chinensis (Chinese tree shrew)
Pathway
tup05200
Pathways in cancer
tup05223
Non-small cell lung cancer
tup05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
tup00001
]
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102492665 (ALK)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
102492665 (ALK)
09162 Cancer: specific types
05223 Non-small cell lung cancer
102492665 (ALK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
tup01001
]
102492665 (ALK)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
tup04090
]
102492665 (ALK)
Enzymes [BR:
tup01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102492665 (ALK)
Protein kinases [BR:
tup01001
]
Receptor tyrosine kinases (RTK)
ALK family
102492665 (ALK)
CD molecules [BR:
tup04090
]
Proteins
102492665 (ALK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
MAM
ALK_LTK_GRD
FXa_inhibition
Nup96
Motif
Other DBs
NCBI-GeneID:
102492665
NCBI-ProteinID:
XP_006172335
LinkDB
All DBs
Position
Un
AA seq
1183 aa
AA seq
DB search
MEEEKGLTEESGSWTVLQGRIGRPENPFRVALEYISSGNRSLSAVDFFALKNCSEGTPPG
SKMALQSSFTCWDGTVLRLGQACDFHRDCAQGEDEGHLCSKLPAGFYCNFENGFCGWTQD
TLSPHAPQWQIRTPKDVQFQDHKGHALLLSTTDVPTFKSATVTSATFPAPMKNSPCELRM
SWLIRGVLRGNVSLVLVENKTGKEQSRMVWNVATNEGLSLWQWTVLPLLDVSDRFWLQMV
AWWGQGSRATVAFDNISISLDCYLTISGEDKMLQNAAPKSRNLFERNSLKETKSWDNISR
QNPIFDPTVHWLFTTCGASGPHGPTQAQCNNAYQNSNLSVVVGSEGPLKGIQIWKVPATN
TYSISGYGAAGGKGGKNTMMRSHGVSVLGIFNLEKDDTLYILVGQQGQDACPSTNQLIQK
VCIGENNVIEEEIRVNRSVHEWAGGGGGGGGATYVFKMKDGLPVPLIIAAGGGGRAYGAK
TETFHSEKLENNSSVLGLNGNSGAAGGNAASNNDPEMDGEDGVSFISPLGILYTPALKVM
EGHGEVNIKHYLNCSHCEVDECHMDPESHKVICFCDHGTVLAEDGVSCIVSPTPEPHLPL
SLILSVVTSALVAALVLAFSGIMIVYRRKHQELQAMQMELQSPEYKLSKLRTSTIMTDYN
PNYCFAGKTSSISDLKEVPRKNITLIRGLGHGAFGEVYEGQVSGMPNDPSPLQVAVKTLP
EVCSEQDELDFLMEALIISKFNHQNIVRCIGVSLQALPRFILLELMAGGDLKSFLRETRP
RPNQPSSLAMLDLLHVARDIACGCQYLEENHFIHRDIAARNCLLTCPGPGRVAKIGDFGM
ARDIYRASYYRKGGCAMLPVKWMPPEAFMEGIFTSKTDTWSFGVLLWEIFSLGYMPYPSK
SNQEVLEFVTSGGRMDPPKNCPGPVYRIMTQCWQHQPEDRPNFAIILERIEYCTQDPDVI
NTALPVEYGPLIEEEEKVPMRPKDPEGIPPLLVSPQQAKREEERKAAPPPLPAPCSGKAA
KKPXAAVFSARAPPGLPAEGGHVNMAFSQSNPPSELHKVQGSRNKPTSLWNPTYGSWFTE
KPASKDRPPARKEHRDRGGCPVPPSAAAAPGRLPGASLLLEPSSLTASVKEVPLFRLRHF
PCGTVNYGYQQQGLPLEATAAPGTGLHEDSILKTKSSVGHAGP
NT seq
3552 nt
NT seq
+upstream
nt +downstream
nt
atggaagaggaaaaggggctcacagaggagagcggaagctggacagtgctgcaaggaaga
attgggcgcccagagaacccattccgtgtggccctggagtatatctcaagtggaaaccga
agcttgtctgcagtggacttctttgccctcaagaactgcagtgaaggaacacccccgggc
tccaagatggcgctgcagagttccttcacttgttgggatggaaccgtcctccggctcggg
caggcctgtgacttccaccgggactgcgcccagggagaagatgagggccacctgtgcagt
aaacttcctgctggtttttactgcaactttgagaatggcttctgtggctggacccaagat
acactctcaccccatgcaccacagtggcagatcaggaccccaaaggatgtccagttccag
gatcacaaaggccatgcccttttgctcagcaccactgatgtccccactttcaaaagtgct
acagtgaccagtgctacgtttcctgcaccaatgaagaactctccatgtgagctccgaatg
tcctggcttatccgcggagtcttgagaggaaacgtgtccttggtgctggtggaaaacaaa
actgggaaggagcaaagccggatggtctggaatgttgccaccaatgaaggcctgagcctg
tggcagtggacggtgttgcctctcctggatgtgtctgacaggttctggctgcagatggtc
gcatggtggggacaaggatccagagccaccgtggcttttgacaatatctccatcagcctg
gactgctacctcaccatcagtggggaggacaagatgctacagaatgcggcacccaagtca
agaaatttgtttgagagaaattcacttaaggaaacaaaatcctgggataatatatcaaga
cagaaccccatctttgaccctacagttcactggctgttcaccacatgtggggccagcggg
ccccatggtcccacgcaggcccagtgcaacaacgcctaccagaactccaacctgagcgtg
gtggtgggcagcgagggccccctgaagggcattcagatctggaaggtgccagccaccaac
acctacagcatctcaggctacggagcggccggcgggaaaggtgggaagaacaccatgatg
cgatcccatggcgtgtccgtgctgggcatcttcaacctggagaaggacgacacgctgtac
atcttggttgggcaacaggggcaagatgcctgccccagcacaaaccagttaatccagaaa
gtctgcattggagagaataacgtgatagaagaggaaatccgcgtgaacagaagcgtgcac
gaatgggcaggaggaggaggaggtgggggtggagccacctacgtgtttaagatgaaggat
ggattgcccgtgcccctgatcattgcagctggtggtggcggcagggcctacggggccaag
acagagacgttccactctgagaaactggagaataactcctcagttctcggcctgaacggc
aattccggagccgcaggtggcaatgcagcctcaaacaatgaccctgagatggatggggaa
gatggggtttccttcatcagtccacttggcatcctgtacaccccggctttaaaagtgatg
gagggccatggggaagtgaatattaagcattacctaaactgcagtcactgtgaggtagac
gaatgtcacatggaccctgagagccacaaggtcatctgcttctgtgaccacgggacggtg
ctggctgaggacggtgtctcctgcattgtgtcgcccaccccggagccccacctgccactc
tcgctgatcctgtccgtcgtcacctctgccctcgtggctgcccttgtcttggctttctcc
ggcatcatgattgtgtaccgccggaagcaccaggagctgcaagccatgcagatggagctg
cagagccctgagtacaagctgagcaagctccgcacctcaaccatcatgactgactacaac
cccaactattgctttgctggcaagacctcttccatcagtgacctgaaggaggtgccccgg
aaaaacatcacccttattcggggtctgggccatggcgcatttggggaggtatatgaaggc
caggtatccggaatgcccaatgacccaagccccctgcaagtggctgtaaagacgctgcct
gaggtgtgttcagaacaggacgaactggatttcctcatggaagccctgatcatcagcaaa
ttcaaccaccagaacatcgtgcgctgcatcggggtgagtctgcaagccctgccacggttc
atcctgctggagctcatggcaggaggagacctcaagtccttcctccgagaaacccgccct
cgtccaaaccagccctcctccctggccatgctggaccttctgcatgtggctcgggacatc
gcctgtggctgtcagtatttggaggaaaaccacttcatccaccgtgacattgctgccagg
aactgcctcttgacctgtccaggtcctggaagagtggctaagattggggacttcgggatg
gcccgagacatctacagagcgagttactacagaaagggaggatgtgccatgcttccagtg
aaatggatgcccccagaggccttcatggaaggaatatttacttccaaaacagacacctgg
tcctttggcgtgctgctgtgggagatcttctctctggggtacatgccgtaccccagcaaa
agcaaccaggaggttttggagttcgtcaccagtggaggacggatggacccacccaagaac
tgccccgggcccgtataccggataatgacgcagtgctggcaacaccagcctgaagacagg
cccaacttcgccatcattttggagaggattgaatactgcacccaggacccggatgtgatc
aacacggctctgccggtagaatacggtccactgatagaagaggaagagaaggtgcccatg
cggcccaaggacccggagggcatccctcctctcctggtctctccgcagcaggccaagcgg
gaggaggagcgcaaggcggcgccccctccgctgccggccccgtgctcgggcaaagccgcg
aagaagccannagcggcggtgttctccgcccgagccccgccgggcctgcccgccgagggg
ggacacgttaacatggcgttctcgcagtccaacccgccgtcggagctgcacaaggtccag
ggctccaggaacaagccgaccagcttgtggaacccgacgtacggctcgtggttcacagag
aagcccgccagcaaggaccgtcctcccgcgaggaaggagcaccgcgaccgcggaggctgc
cccgtcccgcccagcgcggccgcggcgccggggaggctgcccggggcctccctgctcctg
gagccctcctcgctgactgcctccgtgaaggaggtgcccctgttcaggctgcgtcacttc
ccttgtggcactgtcaactacggctaccagcagcagggcttaccgctggaggccaccgcg
gccccggggactgggctccacgaggactccattctaaaaaccaagagcagcgtcggccat
gctgggccctga
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