Terria’s mission: to make the invisible visible. 🗾 Co-founders Ana Belgun and Amber Standley tackled their #DeepQuestion, exploring the profound shift that happens when complex geospatial data and digital twins are made accessible to everyone. Watch the full conversation below. 👇 #Geospatial #Data #DigitalTwin #DeepTech
Main Sequence
Venture Capital and Private Equity Principals
Eveleigh, NSW 15,357 followers
Australia’s deep tech investment fund tackling the world’s biggest challenges
About us
We are Australia’s deep tech investment fund tackling the world’s biggest challenges by turning today’s scientific discoveries into tomorrow’s industries. Main Sequence works closely with scientists, researchers and industry collaborators to create, fund and accelerate new companies and industries that accelerate humanity for a more prosperous future. Main Sequence was set up in 2017 to manage the CSIRO Innovation Fund, founded by the Australian Government and the national science agency to reinvest its historic contributions into the successes of the future. Over the past four years, Main Sequence has invested in 39 companies changing the way healthcare is delivered, food is produced, spaces are connected and more. These investments have led to more than 60 company collaborative projects with universities and 19 projects with CSIRO.
- Website
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http://www.mseq.vc
External link for Main Sequence
- Industry
- Venture Capital and Private Equity Principals
- Company size
- 11-50 employees
- Headquarters
- Eveleigh, NSW
- Type
- Partnership
- Founded
- 2016
- Specialties
- Deep tech, Innovation, Venture capital, and Startups
Locations
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Primary
Get directions
Level 5, 13 Garden St
Eveleigh, NSW 2015, AU
Employees at Main Sequence
Updates
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Over nearly 8 years, we’ve invested over $100m in Physical AI companies, one of those being Breaker. 🤖 Led by Matthew Buffa, Michael Irwin, and Vanja Videnovic, Breaker is building AI agents that enable robots to act, adapt, and collaborate like humans — helping operators control dozens of autonomous systems with real-time, context-aware intelligence. As AI and robotics converge, we’re entering a new era of Physical AI where machines can not only execute tasks, but truly understand intent, context, and complexity. Partnering with SensorOps, Airvolute and Australian Institute for Machine Learning (AIML), Breaker’s innovation is making intelligent autonomy more adaptable, scalable, and human-centric than ever before. With it’s impact is already reaching global shores, recently opening a US office in Austin. 🌏 Read the full investment note by Mike Zimmerman, linked in the comments. 🔗 Welcome to reality, the next frontier of AI is physical. #DeepTech #AI #PhysicalAI #Robotics #Autonomy #FutureOfAI
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What happens when quantum computing becomes an everyday utility? In our latest Deep Questions session, Quantum Brilliance founder and CEO, Mark Luo, discusses a future where quantum power is as common as Wi-Fi. Discover what this quiet revolution unlock for human capability. 👇 #DeepQuestions #Quantum #QuantumComputing #DeepTech
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Our portfolio companies have been busy — with two milestones that show the impact of Australian deep tech on the world. 🌏 🛰️ Terria is partnering with Jacobs and Amristar to support delivery of the Spatial Digital Twin for Landgate’s Spatial WA program, a landmark initiative creating a dynamic, real-time map of the state to power smarter planning and decision-making. ♻️ Samsara Eco has been named as one of TIME’s Best Inventions of 2025 for its enzymatic recycling tech, EosEco, a breakthrough that uses AI-designed enzymes to infinitely recycle plastics, helping fast-track the world’s shift to circularity. #DeepTech #CircularEconomy #ClimateTech #SpatialData #DigitalTwin
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This week, Phil Morle joined Messaginglab’s Grow Everything podcast to unpack a challenge every deep tech founder eventually faces: turning scientific discovery into scalable industry. Phil explains the bottleneck in biotech is no longer invention — it’s orchestration. Phil reflects on the success of our portfolio, from Samsara Eco to Cauldron Ferm, on how they brought their breakthrough ideas to life at scale. In conversation with Erum Azeez Khan and Karl Schmieder, MS MFA, Phil dives into: 🏭 The transition from ‘First-of-a-Kind’ to ‘Next-of-a-Kind’ facilities ♻️ Why nylon recycling advanced faster than PET 📈 How strategic offtakes generate demand before production begins 🚜 Phil’s pragmatic rule for deep tech: “If it doesn’t need a forklift, it’s not relevant.” This one’s a must-listen for anyone building at the intersection of science, scale, and systems. Episode linked in the comments below. 🎧 #DeepTech #Biotech #IndustrialBiotech #Scaleup #Innovation
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Celebrating the innovators shaping Australia’s future. 🏆 We’re proud to see several portfolio companies recognised in The Australian’s Top 100 Innovators in Australia 2025 list — a reflection of their relentless drive to turn frontier science into real-world impact. Congratulations to: 💥 Q-CTRL: Advancing quantum control to make quantum technology useful for business. 💥 Diraq: Building scalable, silicon-based quantum processors. 💥 QuintessenceLabs: Securing the world’s data with quantum-resilient encryption. 💥Quantum Brilliance: Developing room-temperature diamond quantum accelerators. 💥 Alt.Leather: Creating plant-based, plastic-free leather alternatives. 💥 ElectraLith: Transforming critical mineral recovery for a sustainable battery future. 💥 Amber Electric: Reimagining how consumers interact with energy. 💥 Endua: Pioneering clean, long-duration hydrogen energy storage. Each represents the spirit of deep tech through its bold ideas, scientific excellence, and world-changing ambition. The future is being built in Australia, and it’s being built by innovators like these. #Top100Innovators #DeepTech #Innovation #Quantum #ClimateTech #Energy #CircularEconomy
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Spinning groundbreaking research out of the lab is one of the most exciting and complex paths a researcher can take. 🧠 Before you can transform discoveries in quantum, biotech, or climate tech into a venture-ready company, you need to start with a strong legal foundation. Our Senior Legal Counsel Ben Hansky breaks down the key legal fundamentals every deep tech founder should know — from IP ownership and founder alignment to vesting, spin-out agreements, and building an investable cap table. Whether you’re at the bench or the brink of commercialisation, check the comments for your guide to setting up for long-term success. #DeepTech #ResearchCommercialisation #Legal #Startups
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🚀 Deep Tech Week 2025 🚀 was packed with hard lessons, bold visions, and the kind of candour you only get when founders, investors, and partners come together with sleeves rolled up. But the best part? The conversations don’t stop here. We’re capturing the #HotTakes that will shape the future of Australia’s deep tech ecosystem — and we want yours! Share your Deep Tech Week hot take: https://lnkd.in/gC8KFrSn (You might even see it featured in our new podcast Deep Chats on Deep Tech 🎙️) Catch up on all the highlights, funding news, and founder insights in our special newsletter edition 👇 #DeepTech #DeepTechWeek
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Main Sequence reposted this
💥 Hear from Fivecast Co-Founder Duane Rivett, as he answers #DeepQuestions with Main Sequence, discussing how our technology is helping to make the world a safer place.
What does it truly mean to "light the dark"? 💡 We ask Fivecast Co-Founder Duane Rivett in our latest instalment of our #DeepQuestions series. Hear how Duane and his team are working to illuminate the darkest corners of the internet while navigating the complex ethical landscape of surveillance. Listen to the full conversation below 👇 #DeepTech #CyberSecurity #AI
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What does it truly mean to "light the dark"? 💡 We ask Fivecast Co-Founder Duane Rivett in our latest instalment of our #DeepQuestions series. Hear how Duane and his team are working to illuminate the darkest corners of the internet while navigating the complex ethical landscape of surveillance. Listen to the full conversation below 👇 #DeepTech #CyberSecurity #AI