【信号去噪】基于稀疏性 (BEADS) 实现色谱基线估计和去噪附matlab代码和论文

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于 2022-06-11 09:55:15 发布

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该文提出了一种结合色谱峰稀疏性和导数的基线校正和噪声消除方法——BEADS。通过凸优化问题，利用不对称惩罚函数处理色谱峰的非负性，确保算法收敛到唯一最优解。BEADS方法在模拟和真实色谱图数据上的表现优于现有先进方法。

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1 简介

This paper jointly addresses the problems of chromatogram baseline correction and noise reduction. The proposed approach is based on modeling the series of chromatogram peaks as sparse with sparse derivatives, and on modeling the baseline as a low-pass signal. A convex optimization problem is formulated so as to encapsulate these non-parametric models. To account for the positivity of chromatogram peaks, an asymmetric penalty function is utilized. A robust, computationally effificient, iterative algorithm is developed that is guaranteed to converge to the unique optimal solution. The approach, termed Baseline Estimation and Denoising With Sparsity (BEADS), is evaluated and compared with two state-of-the-art methods using both simulated and real chromatogram

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