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- 17α-Estradiol (also known as 17α-E2, 17-epiestradiol, alfatradiol, or estra-1,3,5(10)-triene-3,17α-diol) is a minor and weak endogenous steroidal estrogen that is related to 17β-estradiol (better known simply as estradiol). It is the C17 epimer of estradiol. It has approximately 100-fold lower estrogenic potency than 17β-estradiol. The compound shows preferential affinity for the ERα over the ERβ. Although 17α-estradiol is far weaker than 17β-estradiol as an agonist of the nuclear estrogen receptors, it has been found to bind to and activate the brain-expressed ER-X with a greater potency than that of 17β-estradiol, suggesting that it may be the predominant endogenous ligand for the receptor. (en)
- 17α-雌二醇（英語：17α-Estradiol，缩写17α-E2）也称为17-表雌二醇（17-epiestradiol）或雌-1,3,5(10)-三烯-3,17α-二醇（estra-1,3,5(10)-triene-3,17α-diol）是一种较弱的内源性甾体雌激素，相对其C17上的差向异构体17β-雌二醇（通常就简称为雌二醇）仅在体内占少量。17α-雌二醇的雌激素效价强度只有17β-雌二醇的百分之一，且更亲和中的而非。和上述核受体不同，对在大脑内表达的雌激素細胞表面受體而言，17α-雌二醇的亲和力比17β-雌二醇更高，说明17α-雌二醇是该受体的内源性配體。 (zh)
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- 17α-E2; Alpha-Estradiol; Alfatradiol; 17-Epiestradiol; Estra-1,3,5(10)-triene-3,17α-diol; β-Estradiol (obsolete, misleading) (en)
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- (1R,3aS,3bR,9bS,11aS)-11a-Methyl-2,3,3a,3b,4,5,9b,10,11,11a-decahydro-1H-cyclopenta[a]phenanthrene-1,7-diol (en)
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- 7592 (xsd:nonNegativeInteger)
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- Alfatradiol skeletal.svg (en)
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- 17α-Estradiol (also known as 17α-E2, 17-epiestradiol, alfatradiol, or estra-1,3,5(10)-triene-3,17α-diol) is a minor and weak endogenous steroidal estrogen that is related to 17β-estradiol (better known simply as estradiol). It is the C17 epimer of estradiol. It has approximately 100-fold lower estrogenic potency than 17β-estradiol. The compound shows preferential affinity for the ERα over the ERβ. Although 17α-estradiol is far weaker than 17β-estradiol as an agonist of the nuclear estrogen receptors, it has been found to bind to and activate the brain-expressed ER-X with a greater potency than that of 17β-estradiol, suggesting that it may be the predominant endogenous ligand for the receptor. (en)
- 17α-雌二醇（英語：17α-Estradiol，缩写17α-E2）也称为17-表雌二醇（17-epiestradiol）或雌-1,3,5(10)-三烯-3,17α-二醇（estra-1,3,5(10)-triene-3,17α-diol）是一种较弱的内源性甾体雌激素，相对其C17上的差向异构体17β-雌二醇（通常就简称为雌二醇）仅在体内占少量。17α-雌二醇的雌激素效价强度只有17β-雌二醇的百分之一，且更亲和中的而非。和上述核受体不同，对在大脑内表达的雌激素細胞表面受體而言，17α-雌二醇的亲和力比17β-雌二醇更高，说明17α-雌二醇是该受体的内源性配體。 (zh)
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- 17α-Estradiol (en)
- 17α-雌二醇 (zh)
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