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In molecular biology, the calcium-activated potassium channel beta subunit is a family of proteins comprising the beta subunits of calcium-activated potassium channels. The functional diversity of potassium channels can arise through homo- or hetero-associations of alpha subunits or association with auxiliary cytoplasmic beta subunits. The beta subunit (which is thought to possess 2 transmembrane domains) increases the calcium sensitivity of the BK channel. It does this by enhancing the time spent by the channel in burst-like open states. However, it has little effect on the durations of closed intervals between bursts, or on the numbers of open and closed states entered during gating.

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  • In molecular biology, the calcium-activated potassium channel beta subunit is a family of proteins comprising the beta subunits of calcium-activated potassium channels. The functional diversity of potassium channels can arise through homo- or hetero-associations of alpha subunits or association with auxiliary cytoplasmic beta subunits. The beta subunit (which is thought to possess 2 transmembrane domains) increases the calcium sensitivity of the BK channel. It does this by enhancing the time spent by the channel in burst-like open states. However, it has little effect on the durations of closed intervals between bursts, or on the numbers of open and closed states entered during gating. (en)
dbo:symbol
  • CaKB
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  • 32180016 (xsd:integer)
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  • 1969 (xsd:nonNegativeInteger)
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  • 1032224022 (xsd:integer)
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dbp:caption
  • solution structure of the cytoplasmic n-terminus of the bk beta-subunit kcnmb2 (en)
dbp:interpro
  • IPR003930 (en)
dbp:name
  • CaKB (en)
dbp:pfam
  • PF03185 (en)
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  • 1 (xsd:integer)
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  • CaKB (en)
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  • 8 (xsd:integer)
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rdfs:comment
  • In molecular biology, the calcium-activated potassium channel beta subunit is a family of proteins comprising the beta subunits of calcium-activated potassium channels. The functional diversity of potassium channels can arise through homo- or hetero-associations of alpha subunits or association with auxiliary cytoplasmic beta subunits. The beta subunit (which is thought to possess 2 transmembrane domains) increases the calcium sensitivity of the BK channel. It does this by enhancing the time spent by the channel in burst-like open states. However, it has little effect on the durations of closed intervals between bursts, or on the numbers of open and closed states entered during gating. (en)
rdfs:label
  • Calcium-activated potassium channel beta subunit (en)
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