About: GsMTx-4

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Grammostola mechanotoxin #4 (GsMTx-4, GsMTx4, GsMTx-IV), also known as M-theraphotoxin-Gr1a (M-TRTX-Gr1a), is a neurotoxin isolated from the venom of the spider Chilean rose tarantula Grammostola spatulate (or Grammostola rosea). This amphiphilic peptide, which consists of 35 amino acids, belongs to the inhibitory cysteine knot (ICK) peptide family. It reduces mechanical sensation by inhibiting mechanosensitive channels (MSCs). GsMTx-4 also serves as a cationic antimicrobial peptide against Gram-positive bacteria.

thumbnail
Property Value
dbo:abstract
  • Grammostola mechanotoxin #4 (GsMTx-4, GsMTx4, GsMTx-IV), also known as M-theraphotoxin-Gr1a (M-TRTX-Gr1a), is a neurotoxin isolated from the venom of the spider Chilean rose tarantula Grammostola spatulate (or Grammostola rosea). This amphiphilic peptide, which consists of 35 amino acids, belongs to the inhibitory cysteine knot (ICK) peptide family. It reduces mechanical sensation by inhibiting mechanosensitive channels (MSCs). GsMTx-4 also serves as a cationic antimicrobial peptide against Gram-positive bacteria. (en)
dbo:alternativeName
  • (en)
  • M-TRTx-Gr1a (en)
  • M-theraphotoxin-Gr1a (en)
dbo:iupacName
  • glycyl-cysteinyl-leucyl-alpha-glutamyl-phenylalanyl-tryptophyl-tryptophyl-lysyl-cysteinyl-asparagyl-prolyl-asparagyl-alpha-aspartyl-alpha-aspartyl-lysyl-cysteinyl-cysteinyl-arginyl-prolyl-lysyl-leucyl-lysyl-cysteinyl-seryl-lysyl-leucyl-phenylalanyl-lysyl-leucyl-cysteinyl-asparagyl-phenylalanyl-seryl-phenylalaninamide (2->17),(9->23),(16->30)-tris(disulfide) (en)
dbo:thumbnail
dbo:wikiPageID
  • 72122427 (xsd:integer)
dbo:wikiPageLength
  • 14297 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1122720261 (xsd:integer)
dbo:wikiPageWikiLink
dbp:iupacname
  • glycyl-cysteinyl-leucyl-alpha-glutamyl-phenylalanyl-tryptophyl-tryptophyl-lysyl-cysteinyl-asparagyl-prolyl-asparagyl-alpha-aspartyl-alpha-aspartyl-lysyl-cysteinyl-cysteinyl-arginyl-prolyl-lysyl-leucyl-lysyl-cysteinyl-seryl-lysyl-leucyl-phenylalanyl-lysyl-leucyl-cysteinyl-asparagyl-phenylalanyl-seryl-phenylalaninamide ,,-tris (en)
dbp:name
  • GsMTx-4 (en)
  • M-theraphotoxin-Gr1a (en)
dbp:organism
  • Grammostola rosea (en)
dbp:othernames
  • (en)
  • M-TRTx-Gr1a (en)
  • M-theraphotoxin-Gr1a (en)
dbp:pdb
  • 1 (xsd:integer)
dbp:symbol
  • GsMTx-4 (en)
dbp:taxid
  • 432528 (xsd:integer)
dbp:uniprot
  • Q7YT39 (en)
dbp:wikiPageUsesTemplate
dcterms:subject
rdf:type
rdfs:comment
  • Grammostola mechanotoxin #4 (GsMTx-4, GsMTx4, GsMTx-IV), also known as M-theraphotoxin-Gr1a (M-TRTX-Gr1a), is a neurotoxin isolated from the venom of the spider Chilean rose tarantula Grammostola spatulate (or Grammostola rosea). This amphiphilic peptide, which consists of 35 amino acids, belongs to the inhibitory cysteine knot (ICK) peptide family. It reduces mechanical sensation by inhibiting mechanosensitive channels (MSCs). GsMTx-4 also serves as a cationic antimicrobial peptide against Gram-positive bacteria. (en)
rdfs:label
  • GsMTx-4 (en)
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
foaf:name
  • GsMTx-4 (en)
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License