Simultaneous multislice acquisition with multi-contrast segmented EPI for separation of signal contributions in dynamic contrast-enhanced imaging
Fig 7
Synthetic SMS images (FA = 5°, TR = 30 ms) were disentangled with reconstruction kernels calculated from either ACS with identical (FA = 5°, TR = 30 ms) or different image contrast (FA = 90°, TR = 30 ms).
The resulting normalized signal differences for SG (left) and SSG (right) with respect to the base signal S0 are shown for three levels of SNR in the ACS (1, 5 and 8 averages). Subfigure (a) and (b) depict the first (TE1) and third echo (TE3) when reconstructed with a single, constant kernel (ACS111). In (c) each echo is reconstructed with its corresponding echo in the ACS (ACS123). The subfigures (d), (e) and (f) illustrate these dependencies for SSG. S0-values along the x-axis were binned to a width of 5. On the y-axis are the normalized differences between both reconstructions as formulated in Eq 6, the vertical bars represent the standard deviation of the mean value after binning.
doi: https://doi.org/10.1371/journal.pone.0202673.g007