通过异构网络模型整合目标信息进行药物重新定位附matlab代码.zip

# Drug-repositioning-by-integrating-target-information-through-a-heterogeneous-network-model Drug repositioning is very important for current drug development, considering the high cost and long time of drug development. Drug reporsitioning will at least skip the step of test drug toxity. In the paper, 'Drug-repositioning-by-integrating-target-information- through-a-heterogeneous-network-model. 2014. Bioninformatics'. We put forward a heterogeneous network model by integrating drug-drug similarity, target-target similarity, disease-disease similarity, known drug-target association and known drug-disease assocation. The code used are upload here. reference: Wenhui Wang, Sen Yang, Xiang Zhang, Jing Li. Drug repositioning by integrating target information through a heterogeneous network model. Bioinformatics. 2014 Wenhui Wang, Sen Yang, Jing Li. Drug target predictions based on heterogeneous graph inference. Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. 2013