RNA Therapeutics Symposium 2025

It was a privilege to hear Tamar Grossman, CEO of La Jolla Labs Inc. and Yoseph Barash, Professor of Genetics at the University of Pennsylvania Perelman School of Medicine at #RNAHorizons2025. Their presentations in the session on Computational & AI Applications in RNA Therapeutics reflected the exciting convergence of technology and biology - driving new possibilities for RNA discovery and design. Grateful for their insightful contributions and for the continued dedication of our Scientific Committee in shaping such a forward-looking program. #RNAHorizons2025 #RNA #AI #RNAtherapeutics #Computationalbiology #HCRI #CANCERNA

Our morning session at #RNAHorizons2025 is focusing on Computational & AI Applications in RNA Therapeutics, opening with insightful remarks from Yoseph Barash of the University of Pennsylvania, who set the tone for an engaging exploration of RNA and computational innovation. Aron Popovtzer, Director of the Sharett Oncology Institute at Hadassah Medical Center (Israel), is delivering an insightful talk: “Harnessing RNA-Driven Intelligence to Revolutionize Personalized Cancer Therapy.” An inspiring start to the day - highlighting how collaboration between computation and biology is transforming the RNA research landscape. #RNAHorizons2025 #RNA #AI #Computation #RNAtherapeutics #CancerResearch #Oncology #RNAInnovation #HCRI #CANCERNA

𝗗𝗮𝘃𝗶𝗱 𝗘𝗹𝗹𝗶𝗼𝘁𝘁, Principal Investigator at Newcastle University (UK), presented a fascinating talk titled: “Ultra-Conserved Poison Exons in SR Protein Splicing Regulator Genes: Do These Operate as Tumour Suppressors or Protect the Functions of Specific Cell Types?” #RNAHorizons2025 #RNA #Splicing #CancerResearch #Oncology #GeneRegulation #TumourSuppressors #PrecisionMedicine #RNAInnovation #HCRI #CANCERNA

𝗔𝗻𝘂𝗿𝗮𝗴 𝗣𝗿𝗮𝗯𝗵𝘂 from the The Hebrew University of Jerusalem gave an insightful presentation titled: “Enhancing Anti-Tumor Immune Response by Modulating Splicing to Generate Neoantigens.” #RNAHorizons2025 #RNA #Splicing #Immunotherapy #CancerResearch #Oncology #Neoantigens #PrecisionMedicine #HCRI #CANCERNA

Daniela Palacios from the Consiglio Nazionale delle Ricerche (Italy) shared an engaging presentation titled: “Oligonucleotide-Based Nanotherapies for the Treatment of Skeletal Muscle Diseases.” #RNAHorizons2025 #RNA #Oligonucleotides #Nanotherapy #SkeletalMuscle #MuscleDisease #RNAInnovation #PrecisionMedicine #HCRI #cancerna

Claudio Sette, Principal Investigator at the Università Cattolica del Sacro Cuore delivered an inspiring talk titled:“Splicing Dysregulation: Hallmark and Therapeutic Opportunity in Cancer.” #RNAHorizons2025 #RNA #Splicing #CancerResearch #Oncology #PrecisionMedicine #RNAInnovation #CancerBiology #HCRI #cancerna

Min Wen Ku, Application Scientist at VectorBuilder (UK), delivered an engaging presentation titled: “Advancing RNA Therapeutics with RNA Engineering and Targeted Lipid Nanoparticles Delivery.” #RNAHorizons2025 #RNA #Therapeutics #LipidNanoparticles #RNAEngineering #VectorBuilder #RNAInnovation #PrecisionMedicine #HCRI #cancerna

Andrei Thomas-Tikhonenko from the Children's Hospital of Philadelphia (USA) delivered an insightful talk titled: “Aberrantly spliced cancer proteoforms: If you can’t beat them, eat them!” #RNAHorizons2025 #CancerResearch #Oncology #RNA #Splicing #Proteoforms #TumorBiology #CancerImmunotherapy #PrecisionMedicine #HCRI #CANCERNA

It was a privilege to hear 𝗣𝗿𝗼𝗳. 𝗖𝗮𝗿𝗼𝗹𝗶𝗻𝗲 𝗥𝗼𝗯𝗲𝗿𝘁 and 𝗣𝗿𝗼𝗳. 𝗖𝗮𝗿𝗹𝗼𝘀 𝗖𝗮𝗹𝗱𝗮𝘀 at RNA Horizons 2025. Their presentations captured the essence of this meeting - advancing RNA science through collaboration and clinical insight. Grateful for their thoughtful contributions and for the dedication of the Scientific Committee in shaping such an inspiring program. #RNAHorizons2025 #CancerResearch #RNAtherapeutics #CanceRNA #HCRI

At the intersection of gene expression and disease, 𝗔𝗱𝗿𝗶𝗮𝗻 𝗥. 𝗞𝗿𝗮𝗶𝗻𝗲𝗿 from Cold Spring Harbor Laboratory, USA delivered a masterclass in molecular control. His presentation at #RNAHorizons2025 revealed how SRSF1-regulated alternative splicing orchestrates oncogenic signaling in pancreatic cancer -turning normal RNA processes into drivers of malignancy. This work not only decodes a crucial layer of tumor biology, but also introduces a new therapeutic concept: using splice-switching oligonucleotides (SSOs) to target specific oncogenic isoforms and potentially dismantle cancer’s internal wiring. #RNAHorizons2025 #RNA #Splicing #PancreaticCancer #Oncology #CancerResearch #PrecisionMedicine #CANCERNA #HCRI