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Comment: problem for finding soft power for constructing network in WGCNA algorithm
by
conservativepaola
• 0
That's an interesting problem! Finding the optimal soft power threshold in WGCNA can definitely be tricky. I've found myself experimenting …
Comment: Issue with Soft-Thresholding in WGCNA
by
conservativepaola
• 0
Hi Maria, your dataset looks clean! It's great you've already done the quality control steps. I've had similar issues with pickSoftThreshol…
Comment: competitive enrichment test yields too few significant results, self-contained t
by
Gordon Smyth
52k
The heirarchical nature of GO tends to reduce significant results from competitive tests (because parents compete with children) and increa…
Comment: competitive enrichment test yields too few significant results, self-contained t
by
sophiasteck007
• 0
Thank you for the help
Comment: competitive enrichment test yields too few significant results, self-contained t
by
bbao
▴ 10
Hi Gordon, Thanks for the advice, I gave camera a try, and it yielded around ~1,000 statistically significant gene sets from the same 11,0…
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Answer: Best practice for handling large data (matrix with >2^31-1 non-zero elements) in
Comment: competitive enrichment test yields too few significant results, self-contained t
Answer: competitive enrichment test yields too few significant results, self-contained t
Regarding the issue of background genes in enrichment analysis
Best practice for handling large data (matrix with >2^31-1 non-zero elements) in SingleCellExperiment?
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