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Comment: Should Xenium pseudobulk experiments be analysed like microarrays (limma) or lik
by
richardallenfriedmanbrooklyn
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30
He is of the opinion that the negative binomial model is appropriate to RNASeq because of sequencing and that since Xenium uses probes it i…
Comment: Should Xenium pseudobulk experiments be analysed like microarrays (limma) or lik
by
ATpoint
★
4.9k
Would you share the rationale of your colleague for the sake of discussion?
Comment: Should Xenium pseudobulk experiments be analysed like microarrays (limma) or lik
by
richardallenfriedmanbrooklyn
▴
30
Dear ATpoint,
Thank you. That is also my understanding. A colleague thinks otherwise and specifically asked me to ask Gordon Smyth. I am a…
Comment: Should Xenium pseudobulk experiments be analysed like microarrays (limma) or lik
by
ATpoint
★
4.9k
It's digital counts, not intensities, so naturally you would go with the RNA-seq methods.
Comment: HMP_2019_t2d data origin
by
Blan
•
0
Thanks! However, I don't see anything regarding this study in particular. I would like to access the raw data. In the source publication ci…
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