Home - Translational Cancer Research

Join us at the 9th World Congress of Pediatric Cardiology & Cardiac Surgery

This year Translational Cancer Research (TCR) as well as its sister journals and books published by AME Publishing Company will be on display during this exciting academic event! We would like to seize this great opportunity to meet our authors, editorial board members and readers. You are cordially invited to visit us at Booth 31.

AME and Wolters Kluwer aim to expand access to global medical research through new collaboration

The agreement broadens the reach of nearly 50 Open Access titles, contributing globally to over 5,000 articles

October 2, 2025 — Wolters Kluwer Health announced a new collaboration with AME Publishing Company, an Open Access publisher specializing in medical journals and books, headquartered in Hong Kong, China.

New Impact Factor for Translational Cancer Research: 1.7

We are pleased to announce that Translational Cancer Research (TCR) has attained its latest impact factor update for the 2024 citation year: 1.7.

Translational Cancer Research 2024 CiteScore Released: 2.5

We are pleased to announce that the Translational Cancer Research (TCR) has achieved its 2024 CiteScore: 2.5. TCR ranks as follows across various categories: 261 out of 415 in Oncology, 180 out of 233 in Cancer Research, and 191 out of 346 in Radiology, Nuclear Medicine and Imaging. This milestone underscores our ongoing commitment to publishing impactful research in the field.

Reviewer of the Month (2025)

In 2025, TCR reviewers continue to make outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

Interviews with Outstanding Authors (2025)

In 2025, many authors make outstanding contributions to our journal. Their articles published with us have received very well feedback in the field and stimulate a lot of discussions and new insights among the peers.

Hereby, we would like to highlight some of our outstanding authors who have been making immense efforts in their research fields, with a brief interview of their unique perspectives and insightful views as authors.

TCR 2024 Annual Report

Greetings from the Editorial Office of TCR!

We are pleased to share the 2024 Annual Report of Translational Cancer Research. 2024 has seen much progress for TCR. We hope 2025 will bring greater things to TCR. We would like to thank you for your support and assistance in improving the journal over the past year, and we certainly look forward to your innovations and contributions in 2025.

We would especially like to express our sincere gratitude to the editorial board members, guest editors, reviewers, authors, and readers for all your support and contributions to TCR. We wish you a happy, healthy and prosperous 2025!

Interviews with Editorial Board Members

TCR features a distinguished editorial board, the members of which continue to instill the power of their expertise for the journal’s development. By launching this column, we are glad to introduce to you some of them in the form of interviews, in which they will share their unique career experiences and perspectives. We believe their insights will shed light on the knowledge of related fields.

Interviews with Guest Editors

Over the years, a number of TCR guest editors have made valuable contributions to the journal. This column features interviews with our guest editors, who graciously share their experience in scientific careers and provide insightful perspectives on the special series.

Ferroptosis and cuproptosis prognostic signature for prediction of prognosis, immunotherapy and drug sensitivity in hepatocellular carcinoma: development and validation based on TCGA and ICGC databases

Identification of differentially expressed genes. (A) Heatmap revealed differentially expressed genes; (B) univariate Cox regression analysis; (C) a protein-protein interaction network showing the relationship between ferroptosis-related genes and cuproptosis-related genes.

Bartholin’s gland carcinoma—the diagnostic and management challenges of a rare malignancy—a case report and review of current literature

FDG-avid right inguinal lymph node on axial CT-PET. The green arrow: FDG-avid right inguinal lymph node on axial CT-PET. FDG, fluorodeoxyglucose; CT-PET, computed tomography-positron-emission tomography.

Development of a novel angiogenesis-related lncRNA signature to predict the prognosis and immunotherapy of glioblastoma multiforme

Differences in risk scores for clinical characteristics. (A-D) The correlations between the risk score and sex, age, MGMT status, and IDH1 status were not significant (P>0.05). (E) Among the subtypes, the proneural subtypes had a significantly lower risk score than did the mesenchymal subtypes (P<0.05). **, P<0.01. IDH1, isocitrate dehydrogenase 1; MGMT, O6-methylguanine-DNA methyltransferase; ns, no significance.

Integrated analysis of single-cell and bulk transcriptome identifies a signature based on NK cell marker genes to predict prognosis and therapeutic response in clear cell renal cell carcinoma

Single-cell sequencing analysis of 20,074 cells from 7 ccRCC samples. (A) Pearson’s correlation between nFeature and nCount. (B) PCA plot colored by different samples. (C) Cells were classified into 25 clusters via UMAP algorithm. (D) Eight cell types were identified and annotated by marker genes. (E) Heatmap visualized top 5 marker genes among 8 cell clusters. (F) Visualization of gene expression in cell clusters. PC, principal component; UMAP, uniform manifold approximation and projection; NK, nature killer; ccRCC, clear cell renal cell carcinoma; PCA, principal component analysis.

Development and validation of nomograms to predict early death in non-small cell lung cancer patients with brain metastasis: a retrospective study in the SEER database

ROC curves for the nomograms of the all-cause early death and the cancer-specific early death in the training cohort (A,B) as well as in the validation cohort (C,D). ROC, receiver operating characteristic; AUC, area under the curve.

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Vol 14, No 10 (October, 2025)

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Announcement more

Join us at the 9th World Congress of Pediatric Cardiology & Cardiac Surgery

The the 9th World Congress of Pediatric Cardiology & Cardiac Surgery (WCPCCS) is going to be held at the Hong Kong Convention and Exhibition Centre, Hong Kong, China from December ... More >>

AME and Wolters Kluwer aim to expand access to global medical research through new collaboration

The agreement broadens the reach of nearly 50 Open Access titles, contributing globally to over 5,000 articles More >>

New Impact Factor for Translational Cancer Research: 1.7

We are pleased to announce that Translational Cancer Research (TCR) has attained its latest impact factor update for the 2024 citation year: 1.7. More >>

Original Article

Identification of the immune subtypes associated with the prognosis and immunotherapy of metastatic melanoma

Feng Zhang, Xiaodong Zhang, Huanzhong Su, Longcheng Hong, Yuhui Wu, Chang Shu

PDF Pages: 6136-6151 Full Text (103) Reporting Checklist Peer Review File COI Form Open Access

Identification and validation of an immune-related programmed cell death signature for predicting prognosis and immunotherapy in large-scale multicenter cohorts for lung adenocarcinoma

Zhetao Li, Chuyun Fu, Jie Chen, Wenbo Ji, Zaiqi Ma

PDF Pages: 6152-6171 Full Text (63) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Identification and validation of RAS signaling-related genes for prognostic prediction and immunological characterization in gastric cancer

Jinhong Cao, Jun Liu, Lingling Ye, Xiaojuan Zheng

PDF Pages: 6172-6194 Full Text (62) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The timing of surgery for elderly patients with locally advanced breast cancer

Jiameng Liu, Hehui Mao, Zijie Wu, Wei Zhuang, Yiyin Weng, Juli Lin, Jujiang Guo, Zhipeng Hua

PDF Pages: 6195-6206 Full Text (37) Reporting Checklist Peer Review File COI Form Open Access

Cervical cancer molecular subtype identification and prognosis classification by a metabolism-related gene expression

Xiaohong Chen, Caixia Hong, Guohui Zhang, Bixian Lin, Jingyi Liu, Ronglong Wang, Chunbo Li

PDF Pages: 6207-6221 Full Text (46) Reporting Checklist Peer Review File COI Form Open Access

Epidemiological and clinicopathologic characteristics, and prognostic factors of patients with extra-skeletal osteosarcoma: a Surveillance, Epidemiology, and End Results population study

Zhenzhong Liu, Fapeng Gao, Li Du, Zheng Liu

PDF Pages: 6222-6240 Full Text (49) Reporting Checklist Peer Review File COI Form Open Access

Predictive factors for clinical outcome of palliative ventriculoperitoneal shunt in the treatment of leptomeningeal metastasis

Lingzhao Min, Ningning Zhang, Qing Zhang, Mingzhe Zheng, Yiqian Zhu

PDF Pages: 6241-6247 Full Text (26) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Identification of lysine crotonylation-driven molecular clusters and immune dysregulation in HBV-related hepatocellular carcinoma via bioinformatics and machine learning

Jinlian Li, Linbin Huang, Baoren He, He Xie, Qunying Wu, Limin Chen

PDF Pages: 6248-6268 Full Text (53) Reporting Checklist Peer Review File COI Form Open Access

Transcriptomics combined with in vitro experimental validation probes polyamine metabolic profiles in low-grade gliomas

Linfeng Pan, Huili Chen, Xinyu Zhang, Jing Zhang, Chaoqun Lian

PDF Pages: 6269-6288 Full Text (46) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Ultrasound and immunohistochemical predictors of neoadjuvant chemotherapy response in breast cancer

Yanqiang Ma, Yangyang Zhu, Jiali Zhu, Fang Nie

PDF Pages: 6289-6299 Full Text (43) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Development and validation of nomograms predicting survival in operable breast cancer patients at reproductive age after breast conserving surgery and postoperative radiotherapy based on SEER database

Sirui Zhu, Ke Zhang, Wei Lu, Huaiyu Yang, Chenxuan Yang, Changyuan Guo, Lei Guo, Xuemin Xue, Zhongzhao Wang, Lixue Xuan

PDF Pages: 6300-6315 Full Text (34) Reporting Checklist Peer Review File COI Form Open Access

Identification of cancer-associated fibroblast subpopulation and construction of an immunotherapy signature for gastric cancer

Kunqin Wang, Dong Xue, Chao Yin, Guanghui Wang

PDF Pages: 6316-6329 Full Text (30) Reporting Checklist Peer Review File COI Form Open Access

Integration of single-cell and bulk transcriptomics to explore prognostic and immunotherapeutic characteristics of sodium overload-induced cell death in lung adenocarcinoma

Yilun Shi, Xiangyu Qu, Dayu Liu, Huihong Zhang, Suchen Wang, Jiarui Song, Li Wang, Wenrui Wang

PDF Pages: 6330-6347 Full Text (55) Reporting Checklist Peer Review File COI Form Open Access

Integrative analysis of polo-like kinase family identifies a prognostic signature and validates PLK2 as a therapeutic target in glioma

Chengjun Zheng, Qiaodong Chen, Zheng Fang, Delong Zhang, Yutong Feng, Shuqing Yu, Ying Zhang, Zhaoshi Bao

PDF Pages: 6348-6363 Full Text (43) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Prognostic significance of key immune cell functional alterations in clear cell renal cell carcinoma

Yuhai Wu, Yantao Zhang, Ke Sun, Wenjie Niu, Yanhui Mei, Shimiao Zhu, Changyi Quan

PDF Pages: 6364-6387 Full Text (34) Reporting Checklist Peer Review File COI Form Open Access

Comparative microbiome profiling reveals unique signatures in multiple primary lung cancers

Yun Chen, Yang Wang, Shuai Shen, Jiagui Lu, Qihui Peng, Xiangyun Yan, Hao Peng, Zheyuan Xu

PDF Pages: 6388-6402 Full Text (26) Data Sharing Statement Peer Review File COI Form Open Access

PLCXD2 expression relates to the immune microenvironment and prognosis of head and neck squamous cell carcinoma: a retrospective cohort study

Mingming Tang, Qingwen Chen, Xinjiang Xu, Zihao Zhang, Liang Han, Hao Wu

PDF Pages: 6403-6413 Full Text (39) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

CCT4 as a prognostic biomarker correlated with immune infiltration and hepatocyte dedifferentiation in hepatocellular carcinoma

Xinglin Zhang, Peirong Li, Hongbo Zhao

PDF Pages: 6414-6428 Full Text (33) Reporting Checklist Peer Review File COI Form Open Access

Anti-ovarian cancer effects of forsythiaside A: insights from in vitro and in vivo studies

Haocheng Guan, Yongchao Li, Menglong Xu, Wenqiang Sun, Ruijun Shi, Shuwei Li

PDF Pages: 6429-6441 Full Text (27) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A pentacyclic triterpene tormentic acid inhibits the proliferation and migration of pancreatic ductal adenocarcinoma cells

Mohammed Merae Alshahrani, Ahmed Abdullah Al Awadh

PDF Pages: 6442-6453 Full Text (33) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

shRNA-based PD-1 suppression preserves memory phenotype and function of CD19-targeted CAR-T cell

Jiaxuan Zhao, Han Wu, Zhe Sun, Yeting Cui, Nan Liu, Yixuan Wang, Youyong Wang, Jiangzhou Shi, Tongcun Zhang

PDF Pages: 6454-6468 Full Text (47) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Unveiling PIK3CA mutation: a prognostic beacon in endometrial carcinoma and its immune implications

Shuai Cao, Yucheng Zhao, Lu Zhang, Junhong Zhuang, Peiqi Jia, Dongmei Han, Hao Jin, Liming Xu

PDF Pages: 6469-6482 Full Text (38) Reporting Checklist Peer Review File COI Form Open Access

Methylation-regulated tumor suppressor gene HOXB4 inhibits human lung adenocarcinoma A549 cell invasion and metastasis through the RAP1 signaling pathway

Lingxiang Zhang, Zhong Xu, Shu Wu, Yamen ahmed Muad, Weiyan Peng, Lin Ye

PDF Pages: 6483-6496 Full Text (39) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The role of cancer stem cells in the progression of colorectal cancer and the tumor microenvironment: new perspectives from single-cell RNA sequencing and spatial transcriptomics analyses

Yuting Wu, Xianglin Liu, Wenqiang Liu, Qingliang Jiang, Yangyang Li, Hengyu Li, Liqiang Hao

PDF Pages: 6497-6519 Full Text (29) Peer Review File COI Form Open Access

KRT23 promotes proliferation invasion and metastasis of gastric cancer through epithelial-mesenchymal transition mediated by the PI3K/AKT/mTOR signaling pathway

Yi Xie, Fanghui Zhou, Xuelian Li, Pailan Peng

PDF Pages: 6520-6535 Full Text (35) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

B7 homolog 6 promotes the killing activity of natural killer cells against cervical cancer through the downstream ERK pathway of NKp30

Ruimeng Guo, Ou Chai, Changying Li, Yanying Xu, Xuewang Guo

PDF Pages: 6536-6550 Full Text (27) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

LINC01314 suppresses proliferation and invasion via epithelial-to-mesenchymal transition regulation in lung adenocarcinoma

Wen Zhu, Xue Pan, Anyuan Zhong, Yongkang Huang, Minhua Shi

PDF Pages: 6551-6564 Full Text (25) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Development and validation of a prognostic prediction model for gastric cancer based on lipophagy-related genes

Laibijiang Wusiman, Dingding Song, Alimu Tulahong, Abulajiang Abudukelimu, Juan Liu, Xuying Wei, Shu He, Wenbin Zhang

PDF Pages: 6565-6587 Full Text (29) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Bioinformatics analysis identifies ULK3 as a novel prognostic and immune-related biomarker in esophageal cancer

Kai Cui, Jinxi He, Nan Zhao, Rong Ma, Yanyang Wang

PDF Pages: 6588-6604 Full Text (43) Reporting Checklist Peer Review File COI Form Open Access

Development and validation of a nomogram comprising GLUT1 and clinical characteristics for predicting overall survival in intrahepatic cholangiocarcinoma

Li-Ping Gong, Yulan Weng, Jing Zhou, Xiangqi Huang, Jian-Ning Chen, Dan He, Yi-Wang Zhang, Yongmei Cui, Jing Liang, Chun-Kui Shao

PDF Pages: 6605-6617 Full Text (25) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Integrative analysis of the potential of DISP3 as a biomarker for thyroid cancer

Chenghui Lu, Xufu Wang

PDF Pages: 6618-6636 Full Text (31) Reporting Checklist Peer Review File COI Form Open Access

Liriopesides B inhibits proliferation and metastasis and induces apoptosis of oral squamous cell carcinoma via the PI3K/Akt/mTOR signaling pathway

Jinzhi Wei, Hejia Guo, Binghua Feng, Wei Lv, Xiaoping Su, Cuiping Li, Xuanping Huang

PDF Pages: 6637-6652 Full Text (33) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Intratumoral disulfidptosis heterogeneity in triple-negative breast cancer, a multiomics integration analysis

Zi-Xian Dong, Yang Ou-Yang, Lan Fang, Xiao-Qing Song

PDF Pages: 6653-6666 Full Text (33) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

TIPE3 promotes breast cancer progression and metastasis via the AKT-GSK3β-β-catenin/Snail pathway

Yiling Bai, Jing Wu, Dongmei Yu, Qiang Li, Yan Li, Yufeng Xie

PDF Pages: 6667-6680 Full Text (29) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Multi-omics analysis reveals intratumoral microbiota as modulators of the immune environment within thyroid cancer

Zihao Liang, Jie Gao, Qin Zheng

PDF Pages: 6681-6693 Full Text (32) Reporting Checklist Peer Review File COI Form Open Access

Prognostic prediction nomogram of elderly patients with metastasis colon cancer and distant metastasis pattern: a SEER database analysis

Xing Luo, Jincheng Tang, Wei Peng, Fang Liu

PDF Pages: 6694-6708 Full Text (26) Reporting Checklist Peer Review File COI Form Open Access

Machine learning models for predicting survival in patients of hepatocellular carcinoma with second primary malignancy

Yu Nie, Lu Nie, Boyu Li, Yuanyuan Wang, Liyuan Wang, Xingyan Lv, Runjie Sun, Mengting Xia, Ruiyang Wang, Xing Cui

PDF Pages: 6709-6722 Full Text (38) Reporting Checklist Peer Review File COI Form Open Access

Integrative analysis identified THBS1 as a key prognostic biomarker with therapeutic vulnerability in patients with laryngeal cancer

Shaokun Huang, Xuan Shan, Fan Song, Min Wu, Chaofan Li, Xiaohui Wang, Ruiping Zhao, Juan Ye

PDF Pages: 6723-6737 Full Text (33) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Construction and verification of a prognostic model for cervical cancer based on genes associated with the p53 regulatory pathway

Zhaoming Wu, Jing Zhang, Bohao Sun, Yichen Wu, Nan Wang, Changqing Li

PDF Pages: 6738-6757 Full Text (27) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Unveiling critical genes and molecular subtypes in ovarian cancer: insights into tumor immunity and carbohydrate-lipid metabolism

Yuxuan Zhang, Wei Zhang, Wenli Xie, Xiangyu Wang, Ping Wei

PDF Pages: 6758-6770 Full Text (26) Reporting Checklist Peer Review File COI Form Open Access

Integrated multi-omic analysis unravels the characteristics of the metabolism-related intratumoral microbes and establishes a novel signature for predicting prognosis and therapeutic response in lung adenocarcinoma

Huan Liu, Yueguang Liu, Yixuan Dai, Lei Zhang, Mei Long

PDF Pages: 6771-6790 Full Text (36) Reporting Checklist Peer Review File COI Form Open Access

Decoding the genomic landscape of adenoid cystic carcinoma: a retrospective cohort study of MYB family alterations, NOTCH pathway activation, and clinical outcomes

Jun Wu, Xi Zhao, Yi-Xuan Liu, Ting-Yao Ma, Yue Zhao, Guo-Liang Yang, Xiao-Hong Chen

PDF Pages: 6791-6802 Full Text (26) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Single-cell analysis revealed a diagnostic model of hepatocellular carcinoma based on cancer stem cell-related gene

Yang Ding, Qi Liang, Songbo Ma, Jia Yang, Zengrui Ma, Zhiqi Yang, Baoding Li

PDF Pages: 6803-6813 Full Text (27) Reporting Checklist Peer Review File COI Form Open Access

Role of ¹⁸F-FDG PET/CT in the diagnosis and treatment response assessment of primary pulmonary lymphoma

Yongzhu Pu, Ran Xie, Kun Li, Chunhong Zhang, Sheng Zhao, Xin Liu, Haicheng He, Ningning Chen, Yuqiang Xiao, Qiuyuan Hu, Zhiyong Deng, Long Chen

PDF Pages: 6814-6833 Full Text (27) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

CC/CXC chemokine risk signature at single-cell resolution: a machine learning model for precision stratification in cervical cancer

Bing Xu, Xinyan Shi, Yanfei Liu, Lyuping Xu, Qingxue Zhou

PDF Pages: 6834-6848 Full Text (28) Reporting Checklist Peer Review File COI Form Open Access

Identification of PDGFRB as a prognostic immune-related biomarker in gastric cancer through bioinformatics and clinical analysis

Shujing Wang, Bo Meng, Yuanan Liu, Qiang Wu

PDF Pages: 6849-6863 Full Text (29) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

NSD2 mediates NF-κB and matrix metalloproteinases to drive hepatocellular carcinoma malignant progression

Meng Xiong, Qianshan Ding, Yingjie Wu, Muhammad Jamal, Xingruo Zeng, Yufei Lei, Hengjing He, Di Xiao, Qiuping Zhang, Liang Shao, Xiaoxing Huang, Xinran Li

PDF Pages: 6864-6880 Full Text (49) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Molecular dynamics simulation and single-cell and spatial transcriptomics validate immune and prognostic biomarkers in colorectal cancer and construct a clinical prognostic model

Xuanting Chen, Yuan Zhou, Hongyu Li, Wang Guo, Songqi Li, Zhen Zhang, Qiang Tang

PDF Pages: 6881-6906 Full Text (38) Reporting Checklist Peer Review File COI Form Open Access

Study of non-surgical therapeutic patterns and prognosis in elderly patients with stage II non-small-cell lung cancer: an investigational study based on the SEER database

Lixia Zhang, Xin Xu, Yunbin Gao

PDF Pages: 6907-6918 Full Text (40) Reporting Checklist Peer Review File COI Form Open Access

TOP2A promotes non-small cell lung cancer progression via LDHA-mediated glycolysis and histone lactylation

Qiong Wu, Ye Fan, Weiqin Wang, Feng Hu

PDF Pages: 6919-6939 Full Text (43) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Identification of prognostic genes associated with sphingosine-1-phosphate in gastric cancer to construct a risk mode

Jing Han, Lan Lei, Jiangfeng Wang

PDF Pages: 6940-6959 Full Text (27) Reporting Checklist Peer Review File COI Form Open Access

Development and verification of risk prediction nomograms for overall and specific mortality in primary small bowel cancer: a population-based study

Yingxiang Wu, Wen Luo

PDF Pages: 6960-6974 Full Text (40) Reporting Checklist Peer Review File COI Form Open Access

ATP citrate lyase (ACLY) promotes the occurrence of gastric cancer through regulating lipid metabolism

Sijia Zhang, Yihuang Liu, Xia Zhang, Nailin Zhang, Jianhui Sun, Pingping Chen

PDF Pages: 6975-6989 Full Text (26) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Development and validation of a machine learning-based prognostic model using mitochondrial dysfunction-related genes for colorectal cancer patients

Chang Liu, Yaxuan Li, Jiaxu Song, Yijing Zhao

PDF Pages: 6990-7006 Full Text (29) Reporting Checklist Peer Review File COI Form Open Access

Prognostic value of 18F-fluorodeoxyglucose positron emission tomography/computed tomography metabolic parameters combined with serum apolipoprotein A1 in patients with diffuse large B-cell lymphoma: a clinical study

Zhengong Jia, Lin Liu, Weipeng Li, Hui Li, Shujie Ge, Yongquan Hu

PDF Pages: 7007-7017 Full Text (22) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A novel prognostic tool for triple-negative breast cancer: creating and testing a parthanatos-related gene model

Zitong Yang, Siyi Chen, Jiahong Sun, Guangmin Wu, Delu Mu, Jiandong Wang

PDF Pages: 7018-7036 Full Text (28) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Development and validation of a machine learning model for predicting 3-year overall survival in metastatic nasopharyngeal carcinoma: a SEER database and web visualization study

Lei Qiu, Yinjiao Fei, Yuchen Zhu, Kexin Shi, Jinling Yuan, Gefei Jiang, Xingjian Sun, Yuandong Cao, Weilin Xu, Shu Zhou

PDF Pages: 7037-7052 Full Text (30) Reporting Checklist Peer Review File COI Form Open Access

A novel disulfidptosis-related lncRNAs index to predict prognosis and therapeutic target in hepatocellular carcinoma

Xun-Feng Gao, Xiao-Lu Xu, Jin-Hui Zhang, Heng Zhang, Li-Quan Cai, Feng Gao, Jin-Long Zhang, Dan Yu, Qin-Wen Tai

PDF Pages: 7053-7070 Full Text (33) Reporting Checklist Peer Review File COI Form Open Access

Constructing an immune-related prognostic model and exploring the function of HMGB3, TNFSF4, and CORO2A in breast cancer

Meng Tang, Tingting Huang, Wei Zhang, Chi Wang, Rui Pan, Yaqin Zhao

PDF Pages: 7071-7088 Full Text (32) Reporting Checklist Peer Review File COI Form Open Access

Single-cell analysis of tumor microenvironment immune homeostasis and identification of prognostic biomarkers in head and neck squamous cell carcinoma

Hongyu Xie, Shenling Liao, Libo Liang, Ga Liao

PDF Pages: 7089-7101 Full Text (27) Reporting Checklist Peer Review File COI Form Open Access

Efficacy, safety and cost-effectiveness of chemo-immunotherapy combinations for recurrent or metastatic nasopharyngeal carcinoma: an updated systematic review and cost-effectiveness analysis

Lei Qiu, Qiran Wei, Yachun Hu, Jinling Yuan, Mengxing Wu, Yurong Li, Yuting Xu, Xin Guan, Yuandong Cao, Juan Pu, Zhou Ding, Yinjiao Fei, Weilin Xu, Shu Zhou

PDF Pages: 7102-7118 Full Text (39) Reporting Checklist Peer Review File COI Form Open Access

Integrative single-cell and bulk transcriptomes analyses reveal T cell-related prognostic risk model and tumor immune microenvironment modulation in colorectal cancer

Ping Liu, Yizhou Wang, Shu Huang, Rui Luo, Ruiheng Xie, Jieyv Peng, Ruiyu Wang, Ping Wang, Xiaomin Shi, Wei Zhang, Lei Shi, Xian Zhou, Xiaowei Tang

PDF Pages: 7119-7135 Full Text (25) Reporting Checklist Peer Review File COI Form Open Access

Identification of molecular subtypes for breast cancer based on butyrate metabolism-related genes to assess prognosis and immune landscape

Huitao Yao, Xiuping Hu, Jiazhen Feng, Lunan Tan

PDF Pages: 7136-7156 Full Text (34) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

RNA sequencing and bioinformatics analysis have identified MAST1 as a potential biomarker and therapeutic target for cervical cancer

Zhijia Xie, Tao Shen, Yuhong Wang, Ruyue Ma, Hong Xu, Ruirui Zhang, Hailan Su

PDF Pages: 7157-7169 Full Text (39) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Clinical significance of CD155 expression and correlation with immune cell infiltration in triple-negative breast cancer

Yan Zhao, Jinlu Wang, Tongjun Sun, Sijuan Jiang, Zongyu Xie, Jingru Lai, Ganyu Sang, Xin Jin

PDF Pages: 7170-7185 Full Text (20) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Epidemiological characteristics and prognostic factors of high-grade brainstem glioma for all ages and the establishment of a nomogram

Bowen Huang, Ting Liu, Hongfei Li, Xiang Li, Gonggong Lu, Jiuhong Li

PDF Pages: 7186-7198 Full Text (27) Reporting Checklist Peer Review File COI Form Open Access

A deep learning-based prognostic prediction model for distal cholangiocarcinoma incorporating the metabolism-inflammation marker monocyte-to-high-density lipoprotein cholesterol ratio

Hai-Bin Zhang, Xiao-Ting Han, Lian Wang

PDF Pages: 7199-7213 Full Text (21) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Exploration of efferocytosis-related genes as potential therapeutic targets in endometrial cancer

Huiping Zhang, Man Di, Shan Wang, Mingming Wei, Mingxia Jia, Zhuo Zhou

PDF Pages: 7214-7228 Full Text (26) Reporting Checklist Peer Review File COI Form Open Access

FBXO5 drives hepatocellular carcinoma progression and is a target for tea polyphenol-mediated inhibition

Xinyu Wang, Dandan Yang, Jiao Wang, Zheng Huang, Junjie Gao, Jun Xia, Yingjie Zhang, Jia Ma, Xueshan Pan

PDF Pages: 7229-7244 Full Text (26) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Ferroptosis-associated RNA-binding proteins predict clinical outcomes in head and neck squamous cell carcinoma

Ming Liu, Zhiyu Zhang, Lei Shi, Guanggang Shi

PDF Pages: 7245-7255 Full Text (26) Reporting Checklist Peer Review File COI Form Open Access

Deciphering immune landscapes: an ICD-lncRNA-derived prognostic signature for pancreatic adenocarcinoma

Hao Zhu, Xiaojie Gan, Danyang Shen, Ding Sun

PDF Pages: 7256-7276 Full Text (28) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Immune-related long noncoding RNAs in predicting the prognosis and immune landscape of intrahepatic cholangiocarcinoma: a bioinformatics analysis with experimental verification

Gao Huang, Yuan-Shu Lian, Wen-Ting He, Fang Xiao, Wen-Bo Zou

PDF Pages: 7277-7290 Full Text (28) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The role of liquid-liquid phase separation in hepatocellular carcinoma: single-cell analysis and identification of prognostic biomarkers

Wenjie Lei, Rui Luo, Xiaohong Wang, Xiaomin Shi, Jieyu Peng, Qi Chen, Shiqi Li, Wei Zhang, Lei Shi, Yan Peng, Shu Huang, Xiaowei Tang

PDF Pages: 7291-7310 Full Text (24) Reporting Checklist Peer Review File COI Form Open Access

A novel manganese metabolism- and immune-related prognostic risk model for acute myeloid leukemia

Lin Guo, Yue Cao, Wei-Ying Gu, Yan Lin

PDF Pages: 7311-7328 Full Text (33) Reporting Checklist Peer Review File COI Form Open Access

Radiomics-based machine learning for glioma grade classification: a multicenter study with SHapley Additive exPlanations interpretability analysis

Yumeng Shi, Wei Jiang, Li Zhou, Yu Shi, Xinran Ji, Wenjie Zheng, Hongyu Zhao, Ninghua Yao

PDF Pages: 7329-7346 Full Text (29) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The systemic immune-inflammation index in the efficacy prediction of neoadjuvant chemotherapy in patients with endometrial cancer

Jing Lin, Lingli Gu, Filomena Marino Carvalho, Luigi Della Corte, Jie Dang

PDF Pages: 7347-7357 Full Text (28) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

CXCR3 enhanced murine chimeric antigen receptor T cells in the treatment of solid tumors

Xiangzhi Zhang, Luyu Zhu, Qiang Wang, Qinggang Xu, Xiaoyan Wang, Feng Yu

PDF Pages: 7358-7373 Full Text (44) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A diagnostic test evaluation: dynamic optical functional imaging system for early-stage breast cancer detection

Xiangming He, Linyin Fan, Jian Huang, Xiping Zhang, Naohiro Ishii, Xiaojia Wang, John Zhang

PDF Pages: 7374-7386 Full Text (50) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

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Below are the latest Translational Cancer Research articles published online ahead of print publication.

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Published online: 05 November 2025

Journal highlight more

Translational Cancer Research is an international, open access, peer-reviewed journal indexed in Scopus and Science Citation Index Expanded (SCIE), focusing on original, science-based researches on clinical, basic and translational aspects. It publishes laboratory studies of novel therapeutic interventions, clinical trials which evaluate new treatment paradigms for cancer, results of novel research investigations which bridge the laboratory and clinical settings including risk assessment, cellular and molecular characterization, prevention, detection, diagnosis and treatment of human cancers with the overall goal of improving the clinical care of cancer patients and etc.