Did you catch CN BioSenior scientists, Dr. Morné van Wyk and Dr. Marco Ortiz discuss the science behind our latest publication in Drug Metabolism and Disposition - A primary human Gut/Liver microphysiological system to estimate human oral bioavailability? If you missed the live event, you can now watch the presentation on demand 👉 MPS and In Silico Modeling: The next generation of bioavailability prediction 🔗https://lnkd.in/e3ujgGBT
CN Bio
Biotechnology Research
Cambridge, England 8,583 followers
Generate human-specific efficacy and safety data with PhysioMimix® microphysiological systems.
About us
CN Bio is a leading organ-on-a-chip (OOC) company that enables researchers to improve the accuracy and efficiency of preclinical drug discovery. Our PhysioMimix® suite of microphysiological systems, 3D-validated cells, consumable plates, and Contract Research Services facilitate the prediction of human responses to drug exposure, in the presence or absence of disease, so that new medicines can be brought to market more rapidly, cost-effectively and using fewer animals. Utilizing primary cells, our perfused single (Lung, Liver), and multi-organ (Intestine/Liver, Lung/Liver) models recapitulate the microarchitecture, microenvironment and function of their human counterparts in vitro. The approach provides a viable alternative to animal models where translatability to humans is predicted to be poor and for testing advanced drug modalities where human-specific targets and pathways are required. They generate physiologically relevant, human-translatable, mechanistic data that enables researchers to progress only the safest and most efficacious drugs into in vivo animal studies and be better prepared for clinical trials. Please follow us for regular updates. It starts here.
- Website
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http://www.cn-bio.com
External link for CN Bio
- Industry
- Biotechnology Research
- Company size
- 51-200 employees
- Headquarters
- Cambridge, England
- Type
- Privately Held
- Founded
- 2008
- Specialties
- Organ-on-a-chip, Hepatitis B, drug discovery, liver disease, containment level 3 laboratory, microfluidic cell culture, precision biology, non-alcoholic steatohepatitis, Organ-on-Chip, Preclinical drug discovery, Microphysiological systems, Safety Toxicology, non-alcoholic fatty liver disorder, Contract Research Services, PhysioMimix OOC, Drug-induced liver injury, ADME, disease modeling, 3D cell culture, Aminal alternative, New Alternative approaches, COVID 19, Drug absorption, Drug metabolism, Bioavailability, Respiratory infection, and DILI
Locations
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Primary
Get directions
332 Cambridge Science Park
Milton Road
Cambridge, England CB4 0WN, GB
Employees at CN Bio
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Sarah Payne
Marketing Director at CN Bio Innovations
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Andrew Murray
Lead Embedded Software Engineer | RTOS, C/C++, ARM Microcontrollers | Driving Product Development from Concept to Market | Biotech, Life Sciences…
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Joe Parisi
Director of US Sales at CN Bio specializing in Organ on a Chip Technology
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David Scales
Board Advisor at CN Bio Innovations
Updates
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We're looking for a Research Assistant to join our Biology team and support contract research projects. 🧬 Are you passionate about cutting-edge biological research and ready to make an impact in a dynamic lab environment? What you'll be doing: - Culturing cell lines and primary cells to maintain healthy stocks - Preparing and running organ-on-a-chip experiments using the CN Bio PhysioMimix system - Performing a range of biological assays including ELISAs, microscopy, DNA/RNA extractions, and qPCR - Analyzing data and producing high-quality internal reports If you're detail-oriented, proactive, and excited by innovative science, we’d love to hear from you! 💡 More details about the role and how to apply here: https://lnkd.in/epu9kHmZ
We're looking for a Research Assistant to join our Biology team and support contract research projects. 🧬 Are you passionate about cutting-edge biological research and ready to make an impact in a dynamic lab environment? What you'll be doing: - Culturing cell lines and primary cells to maintain healthy stocks - Preparing and running organ-on-a-chip experiments using the CN Bio PhysioMimix system - Performing a range of biological assays including ELISAs, microscopy, DNA/RNA extractions, and qPCR - Analyzing data and producing high-quality internal reports If you're detail-oriented, proactive, and excited by innovative science, we’d love to hear from you! 💡 More details about the role and how to apply here: https://lnkd.in/epu9kHmZ
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🚀 Introducing The PhysioMimix® Core microphysiological system – Your universal end-to-end Organ-on-a-chip solution! Launched today, it's the only microphysiological system on the market with validated performance across single-organ, multi-organ, and high-throughput configurations. PhysioMimix Core makes Organ-on-a-chip easy to: ✔ Adopt – Start simple for immediate productivity ✔ Adapt – Flexibility to grow with your research needs ✔ Scale – To match immediate and future demand With unrivaled simplicity, flexibility, and scalability, the new PhysioMimix Core mimics physiology like no other for future-proofed Organ-on-a-Chip research. 👉 Learn more: https://bit.ly/3KFMSQO 👉 Explore the features and benefits: https://bit.ly/4nRRJwW #PhysioMimixCore #OrganOnAChip #LikeNoOther #EasyToAdopt #EasytoAdapt #EasyToScale
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The consensus was clear at the WC13 Rio - World Congress on Alternatives and Animal Use in the Life Sciences, the adoption of NAMs and MPS is no longer a question of "if," but rather "how fast." Read this blog with insights from our CSO, Dr. Tomasz Kostrzewski first visit to the conference.
Check out the latest CN Bio blog with insights from my recent trip to the WC13 conference, highlighting the rapidly changing landscape for new alternatives to animal test.... https://lnkd.in/e2gqyUt4
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In a recent feature with Business Focus Magazine, our CEO, Dr. Paul Brooks shares his vision for CN Bio's growth and the strategic direction under his leadership. He explores the transformative potential of Organ-on-a-chip (OOC) technology in reshaping preclinical research and highlights a pivotal moment for the industry, where regulatory momentum is accelerating the shift away from animal testing in favour of more human-relevant models. 👉 Discover how CN Bio is leading this change and what the future holds for OOC innovation. 🔗https://bit.ly/4o7m5v2
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📣The CN Bioteam is getting ready to for the Safety Pharmacology Society's 2025 Annual Meeting in Utrecht, The Netherlands! Swing by our poster: Assessment of Species-Specific Hepatotoxicity Profiling in Cross-Species MPS Liver Models and join Isavella Georgiades for the poster presentation during two sessions: 🗓️ 14 October 2025, Tuesday 🕙 14:00 -15:00 And again on 🗓️ 15 October 2025, Wednesday 🕙 14:00 -15:00 Lead Scientist Emily Richardson will also be there to discuss all things Organ-on-a-chip, specially how the technology can be applied to your preclinical safety assessment workflows. 👉If you'd like to arrange a proper meeting, give us a shout in the comments, send us a message, or use the link below and get in touch. 🔗https://bit.ly/3VTvdYc #CNBioAt #SPS2025
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📈 When you want to scale up without compromising your data quality, the PhysioMimix Sigle Organ Higher-Throughput System is your go to. ✅ Multi-chip plate-based consumables - 6 to 48 chips per plate ✅ Run 1 to 6 plates simultaneously ✅ Screen up to 288 samples per run with the Liver-48 plates PhysioMimix® grows with your research - scalable, cost-effective, multiomics-ready! 👉 Ready to scale your OOC workflow? Discover more: https://bit.ly/4pUz05n
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October marks 🌎 International Liver Month, a time to spotlight one of the body’s most resilient yet vulnerable organs. According to the Journal of Hepatology, over 2 million deaths annually are attributed to liver disease, that's 1 in every 25 deaths worldwide! In this new article from Technology Networks, Dr. Sarah Payne from CN Bio, explores how advanced human models and machine learning are transforming liver research, offering hope for earlier detection, better understanding of metabolic disorders, and accelerated drug development. Discover why now is the time to rethink how we study conditions like MASLD, type 2 diabetes, and alcoholic liver disease. Learn how microphysiological systems (MPS) and AI tools can overcome the limitations of traditional preclinical approaches, leading to a smarter and more efficient methods of therapeutic development through a synopsis of published customer insights. 👉Can human-relevant models and AI help reverse the rise in liver disease? Read the full article to find out. 🔗https://bit.ly/4nDc7Sr
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🚀 When flexibility is key, the PhysioMimix® Multi-organ System adapts to your evolving research needs: 🔹 Seamlessly transition from single-organ to multi-organ studies 🔹 Gain deeper mechanistic insights into disease states 🔹 Uncover human inter-organ cross talk effects 🔹 Study reactive metabolite-driven and multi-organ toxicity 🔹 Evaluate drug ADME & bioavailability PhysioMimix’s open architecture empowers you to tailor models and assays to your specific context of use. 👉 Ready to go further? Discover more: https://bit.ly/4pSGoxS
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📰 Our September Newsletter is live! This month, we dive deep into the industry's pulse. Our CEO and CSO share their perspectives on OOC market momentum and the latest regulatory trends. Are you seeing the same inflection point? Dive into this quick read and let us know your perspective in the comments! 👇 #Newsletter #MonthlyRecap #OrganOnAChip #CNBioAt