Muhdo Health

𝐒𝐞𝐚𝐬𝐨𝐧𝐚𝐥 𝐀𝐬𝐭𝐡𝐦𝐚 As we say goodbye to the summers sun and all start to head indoors for the winter, do you find that either yourself or members of your family seem to suffer more with asthma or seasonal asthma? Lots of things can trigger an asthma attack or tight chest, from pollution levels, central heating, or dust mites. But nobody seems to mention nutrition and what deficiencies in your diet will most probably be causing the asthma in the first place? Asthma is largely caused through a deficiency in 3 key nutrients: magnesium, manganese, and essential fatty acids. Essential fatty acids such as Omega 3’s are required by the lungs as a raw material to create a hormone named E Prostaglandins. The purpose of the E prostaglandins is to keep the bronchi in the lungs and trachea open, as they are a potent bronchodilator. F prostaglandins, however, are bronchoconstrictors, which reduce and narrow the width of the airways. If you have insufficient levels of E prostaglandins, then the bronchi and trachea will close, which can lead to asthma. Asthma UK talks of controlling your inflammation in your airways with your inhaler, but as usual, no mention of how E prostaglandins are fundamentally important, or the importance of the key nutrients that will help reduce your symptoms. There has been a huge amount of research indicating that specific minerals and essential fats are required to reduce the chances or severity of asthma, so why this information isn’t readily available to asthma suffers is a complete mystery. One reason could be simply that there are no large corporate profits to be made from the manufacture or sale of vitamins, minerals, and natural remedies for asthma, which are largely unpatentable. Meaning that there is simply no incentive for funding this critical area of research, and is completely overlooked and neglected. We should also mention some other key ingredients which might help alleviate asthma if introduced into your diet: 𝐋𝐢𝐪𝐮𝐨𝐫𝐢𝐜𝐞 Liquorice has a soothing, prednisone-like effect on the bronchioles and upper respiratory tract. The tea being particularly good for asthma as well as sore throats. 𝐆𝐢𝐧𝐤𝐠𝐨 𝐁𝐢𝐥𝐨𝐛𝐚 Ginkgo biloba contains a component called Ginkgolides, which has anti platelet activating factors for asthma. Ginkgolide B, therefore, is an extremely useful nutrient for the treatment of asthma. Also remember to reduce the amount of gluten in your diet, so no bread, pasta or wheat-based breakfast cereals, which other than processed/fast foods are probably the food groups that are causing the most amount of damage to our health. Gluten can in some instances slowly destroy the intestinal lining and thus reduces your ability to absorb the vitamins and minerals etc that you need. Plus, the vast majority of breads and cereals which contain gluten are extremely pro-inflammatory and void of any beneficial nutrients.

𝐈𝐬 𝐆𝐚𝐫𝐥𝐢𝐜 𝐭𝐡𝐞 𝐒𝐞𝐜𝐫𝐞𝐭 𝐭𝐨 𝐋𝐨𝐧𝐠𝐞𝐯𝐢𝐭𝐲? The health benefits of garlic have been known for a long time, unless you were a vampire, of course, and generally tried to avoid it.🧛♂️ Garlic contains organosulfur compounds, which give cloves their characteristic odour and health benefits and can help to prevent the development of cancer, cardiovascular, neurological, and liver diseases as well as allergies and arthritis. For example, epidemiological studies have shown that consuming garlic more than three times per week (which might affect your social life!!!) can significantly lower the risk of different types of cancer, such as gastric, stomach and colon. Foods rich in organosulfur compounds increase histone acetylation by inhibiting histone deacetylases, enzymes which remove acetylation from DNA 🧬  (Nian et al. 2009). Histone acetylation triggers tumour suppressing genes, which may decrease your chance of getting cancer. Eating garlic and other alliums have been shown to decrease the risk of cancer (Fleischauer et al. 2001, El-Bayoumy et al. 2006, Milner 2006, Myzak and Dashwood 2006, Liu et al. 2007, Millen et al. 2007,Pittler and Ernst 2007, Sener et al. 2007, Nagini 2008 ). Muhdo Health research indicates one of the reasons why garlic is so fantastic in keeping you fit and healthy is due to the allyl sulfides in increasing the activity of glutathione S-transferase (GST) and modulating the effects of the (CYP1A1, 1A2 and 1B1) genes. While most meta-analyses have used garlic in the form of garlic powder supplements, current evidence suggests aged garlic extract (AGE) to be a more reliable treatment option. Aged garlic extract is regarded as safe and more tolerable than garlic powder, and superior to raw or cooked garlic in relation to its antihypertensive properties.

𝐓𝐢𝐜𝐤 𝐓𝐨𝐜𝐤..𝐓𝐢𝐜𝐤 𝐓𝐨𝐜𝐤 ⏱️ What is your Biological Clock? Wikipedia states that “Ageing is the process of becoming older”,  and “Longevity” is sometimes used as a synonym for “Life expectancy”. In most instances we often just look at ageing in one dimension, which is the representation in time ⏱️ and how many years you have been alive. However, in reality, a multitude of aspects surrounding your lifestyle such as diet 🥗, stress 🤯, exercise 🏋️♂️, sleep 😴, as well as your environment will affect the rate to which we age. 𝐂𝐡𝐫𝐨𝐧𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐚𝐠𝐞 ⏱️ 𝐕𝐬 𝐁𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐚𝐠𝐞.🧬 Most of us will be completely unaware that we actually have two ages: Chronological age refers the exact number of years you have been alive, and as predictable as night follows day 🌞, your date of birth and age cannot be altered. While biological age 🧬 is a true reflection of how your cells are ageing and how they have been affected by exogenous and endogenous stressors, which will affect your epigenetics. Biological age is a very well-defined scientific term. It is not a loosely defined marketing term. To date there are over 3000 scientific publications on biological age and epigenetics, so it is very well characterised. Biological ageing includes inability to fight cancer/disease 🦠, lack of functioning proteins, energy production in the body, nutrient function, loss of circadian rhythm, increased inflammation 🔥, loss of new cell regeneration, and many more factors. When proteins lose function, the body cannot carry out the necessary functions, for instance, memory, eyesight, hearing, the ability to properly digest nutrients, to metabolise sugars and fats, fight disease, increased development of autoimmune diseases, etc. The Science of Muhdo Health🧬 Over the last 8 years Muhdo Health has been pioneering Epigenetic 🧬analysis, which helps each of us to understand our biological age and better predict our future health, bridging the gap between consumer wellness and technology. This will allow people to be more proactive in helping to manage their health and wellbeing through lifestyle changes. Muhdo is extremely unique in our approach and methodology, as we combine DNA & Epigenetic 🧬 data, with over 950,000~ epigenetic markers, a large customer database, time stamped, time series trend data overlapped with health metrics, fitness 🏋️♂️ 🏃♀️trackers, pollution levels and lifestyle 📲 data. We have made huge advancements in DNA & Epigenetic 🧬 testing technology 🤖 and understanding an individual’s cellular architecture that provides individuals with detailed insights into their genetic makeup, including information on nutrition 🥗, fitness 🏃♀️, and health risks.☠️ Making technological innovations in personalised healthcare and thus making this technology more accessible, affordable, and straightforward for everyone to utilise each day in a cost-effective manner.

𝐓𝐡𝐞 𝐍𝐞𝐰 𝐄𝐫𝐚 𝐨𝐟 𝐄𝐩𝐢𝐠𝐞𝐧𝐞𝐭𝐢𝐜 𝐂𝐥𝐨𝐜𝐤𝐬🧬 𝐄𝐩𝐢𝐠𝐞𝐧𝐞𝐭𝐢𝐜 𝐀𝐠𝐞𝐢𝐧𝐠, 𝐟𝐫𝐨𝐦 𝐂𝐨𝐦𝐩𝐥𝐞𝐱𝐢𝐭𝐲 𝐭𝐨 𝐂𝐥𝐚𝐫𝐢𝐭𝐲 Albert Einstein famously once said… "𝘐𝘧 𝘺𝘰𝘶 𝘤𝘢𝘯'𝘵 𝘦𝘹𝘱𝘭𝘢𝘪𝘯 𝘪𝘵 𝘴𝘪𝘮𝘱𝘭𝘺, 𝘺𝘰𝘶 𝘥𝘰𝘯'𝘵 𝘶𝘯𝘥𝘦𝘳𝘴𝘵𝘢𝘯𝘥 𝘪𝘵 𝘸𝘦𝘭𝘭 𝘦𝘯𝘰𝘶𝘨𝘩." We're pleased to say that we (Muhdo Health) had our DNA methylation clock 🧬 validated, published and peer reviewed in June this year.📚🔬 👉 https://lnkd.in/eJFw8FCr 👈 This is a huge stride forward for the team and UK 🇬🇧Science in general. We were the first DNA and Epigenetics 🧬company globally to launch a biological age and epigenetics app back in 2019 just before the pandemic. And have now validated in many ways our unique science 🔬with the help of Dr. Henry Chung from the University of Essex 𝐏𝐫𝐞𝐜𝐢𝐬𝐢𝐨𝐧 𝐦𝐞𝐞𝐭𝐬 𝐬𝐢𝐦𝐩𝐥𝐢𝐜𝐢𝐭𝐲. 𝐀𝐛𝐬𝐭𝐫𝐚𝐜𝐭 𝐁𝐚𝐜𝐤𝐠𝐫𝐨𝐮𝐧𝐝/𝐎𝐛𝐣𝐞𝐜𝐭𝐢𝐯𝐞𝐬: DNA methylation profiles have emerged as robust biomarkers of ageing, leading to the development of “epigenetic clocks” that estimate biological age. Most established clocks (e.g., Horvath’s 353-CpG pan-tissue clock and Hannum’s 71-CpG blood clock) require dozens to hundreds of CpG sites. This study presents a novel saliva-specific epigenetic clock built on 10 sites identified from Illumina MethylationEPIC (850 k) array data. 𝐌𝐞𝐭𝐡𝐨𝐝𝐬: Saliva DNA methylation was analysed from 3408 individuals (age range 15–89 years, 68% male, 32% female, no diagnosed disease) from the Muhdo Health Ltd. dataset (2022–2024), and 10 CpG sites were selected where methylation levels showed the strongest positive correlations with chronological age (Pearson r = 0.48–0.66, p< 1 × 10−20). These CpGs map to genes involved in developmental and metabolic pathways (including ELOVL2, CHGA, OTUD7A, PRLHR, ZYG11A, and GPR158). A linear combination of the 10 methylation sites was used to calculate a “DNA methylation age”. 𝐑𝐞𝐬𝐮𝐥𝐭𝐬: The 10-CpG clock’s predictions were highly correlated with chronological age (r = 0.80, R2 = 0.64), with a mean absolute error of ~5.5 years. Its performance, while slightly less precise than Horvath’s or Hannum’s multi-CpG clocks, is notable given the minimal marker set. It was observed that all 10 clock CpGs undergo age-related hypermethylation. The biological significance of these loci is discussed, along with the potential health and forensic applications of a saliva-based epigenetic age predictor. 𝐂𝐨𝐧𝐜𝐥𝐮𝐬𝐢𝐨𝐧𝐬: This study demonstrates that a saliva-specific epigenetic clock using only 10 CpG sites can capture a substantial portion of age-related DNA methylation changes, providing a cost-effective tool for age estimation.

𝐍𝐞𝐰𝐒𝐜𝐢𝐞𝐧𝐭𝐢𝐬𝐭 𝐒𝐮𝐧𝐧𝐲 𝐃 ☀️𝐡𝐞𝐥𝐩𝐬 𝐭𝐨 𝐬𝐥𝐨𝐰 𝐛𝐢𝐨𝐥𝐨𝐠𝐢𝐜𝐚𝐥 𝐚𝐠𝐞𝐢𝐧𝐠! An interesting and New study making the rounds is featured in the NewScientist with regards to Omega 3 and Vitamin D having a positive effect on biological ageing We (Muhdo Health) have actually seen the same with our own DNAm 🧬 research over the last 8 years for a whole variety of nutrients such as vitamin D☀️ and Omega 3🐟 Vitamin D ☀️ Vitamin D, often referred to as the "sunshine vitamin," is a fat-soluble vitamin critical for a wide range of biological processes ·      Activates key genes FOXO3 and SIRT1 to support Longevity. ·      Supports BDNF, promoting Brain 🧠Function and Mental health. ·      Regulates VDR gene activity to Enhance Immunity.🦠 ·      Supports Heart Health by influencing Inflammatory Pathways.🔥 Vitamin D (N = 1780) 46.2 years was the average chronological age of vitamin D3 users.☀️ 42.1 years was the average biological age (4.1 years younger) as measured by our Epigenetic clock (methylpace)🧬 90.7% of users who take Vitamin D3 ☀️ state subjectively they are in either great or excellent health.🥳 80% of users who take Vitamin D3 ☀️state they sleep for 7-9 hours per night😴 Vitamin D3 ☀️affects the expression of the gene 🧬GPR158 a major component in the methylpace algorithm The GPR158 gene 🧬encodes a G-protein-coupled receptor (GPCR) protein implicated in various physiological processes, including neuronal 🧠signalling and stress response Emerging research has connected GPR158 🧬to the regulation of ageing and lifespan, particularly through its role in stress resilience and metabolic pathways. 1. 𝐒𝐭𝐫𝐞𝐬𝐬 𝐑𝐞𝐬𝐢𝐥𝐢𝐞𝐧𝐜𝐞:🤯 GPR158 is involved in regulating stress pathways in the brain🧠, particularly within the prefrontal cortex. Studies in animal models suggest that GPR158 activity can modulate responses to chronic stress🤯, which is a known contributor to accelerated ageing and age-related diseases. 2. 𝐌𝐞𝐭𝐚𝐛𝐨𝐥𝐢𝐜 𝐑𝐞𝐠𝐮𝐥𝐚𝐭𝐢𝐨𝐧: GPR158 has been linked to energy metabolism and insulin sensitivity, which are key factors in ageing. Dysregulation in energy metabolism and insulin signalling pathways can lead to age-related conditions like diabetes, cardiovascular disease and neurodegeneration.🧠 3. 𝐍𝐞𝐮𝐫𝐨𝐝𝐞𝐠𝐞𝐧𝐞𝐫𝐚𝐭𝐢𝐨𝐧 𝐚𝐧𝐝 𝐁𝐫𝐚𝐢𝐧 𝐀𝐠𝐞𝐢𝐧𝐠:🧠 GPR158 is enriched in brain regions critical for cognitive functions, such as memory and decision-making. Altered GPR158 expression has been associated with cognitive decline and neurodegenerative diseases, including Alzheimer's disease, which are hallmarks of ageing. 4. 𝐋𝐢𝐟𝐞𝐬𝐩𝐚𝐧 𝐄𝐱𝐭𝐞𝐧𝐬𝐢𝐨𝐧:🧬 Animal studies have shown that modulating GPR158 activity may influence lifespan. For example, reduced expression of GPR158 might enhance resistance to oxidative stress and improve cellular health, which are essential for longevity.

𝐇𝐨𝐰 𝐃𝐨𝐞𝐬 𝐓𝐡𝐢𝐬 𝐆𝐞𝐧𝐞 𝐚𝐟𝐟𝐞𝐜𝐭 𝐘𝐨𝐮𝐫 𝐒𝐤𝐢𝐧’𝐬 𝐇𝐞𝐚𝐥𝐭𝐡? “𝐓𝐡𝐞 𝐂𝐥𝐨𝐜𝐤 𝐆𝐞𝐧𝐞”.⏱️🧬 Some interesting research by Joseph S. Takahashi, PhD from the University of Texas Southwestern Medical Center who has been studying a particular gene called the Clock ⏱️gene 🧬, which was the first mammalian gene to be identified and is known for affecting our circadian rhythm and skin health. This one gene 🧬 will affect various biological functions from gaining weight to your immune system working correctly. One study conducted by Dr. Takahashi refers to skin health and UV damage and found that we have a specific enzyme associated with the Clock gene 🧬, which is required to repair UV damage caused by the sun.🌞 This enzyme also works to our circadian cycle and is inhibited by eating 🍔 foods outside of our usual eating patterns, so perhaps those late-night snacks might be affecting how damaged your skin gets when you go out in the sun.🌞 "This finding is surprising. I did not think the skin was paying attention to when we are eating," reports Dr Takahashi, holder of the Lloyd B. Sands Distinguished Chair in Neuroscience. Our 24-hour body clock cycle is tremendously important in keeping us fit and healthy, as it affects our hormones, eating habits and reduces the chances of us become ill.🤒 It is thought that many of our metabolic pathways and enzymes are geared up and ready to perform during daylight hours, with their ability to process and metabolise our food reducing after a 12-hour window. After 12 hours, our ability to process the foods 🍔, especially carbohydrates, gets reduced and insulin sensitivity increases. "It is likely that if you have a normal eating schedule, then you will be better protected from UV during the daytime. If you have an abnormal eating schedule, that could cause a harmful shift in your skin clock,” adds Dr. Takahashi. So, the takeaway message is to align our circadian rhythm 🌞🌜with our eating habits as best we can, and avoiding late night encounters with the fridge, which will help with your skins ability to repair and heal.

Creatine. The New Longevity supplement! But why? Creatine for those of you that don’t know has been the superstar gym, sport, and training supplement for well over 3 decades, offering a whole variety of benefits, such as increasing muscle size, improving physical performance and energy production. But there are also many other positive health benefits and especially in the longevity world to be gained from creatine other than the well-documented performance related ones. For instance, creatine has been shown to lower both inflammation and cortisol levels, as well as crucially being involved in a process called the methylation cycle and DNA methylation. DNA methylation 🧬 is a process that is essential to life, and which happens billions of times per second, where tiny chemical markers called methyl groups (made in the methylation cycle) will attach to your DNA. These methyl groups act like billions of switches, which will either hypo (low) or hyper (high) methylate regions across your genome, which will then affect how specific genes and biological processes function. Interestingly the majority of methylation occurs in your liver, so having a few glasses of wine each evening with dinner is probably one of the worst things you can do from a genetic and longevity point of view. And around 80 % of methylation is used to make two things. 1.     Phosphatidylcholine 2.    Creatine So, supplementing with both can be extremely useful and help to conserve methylation and help it to run more smoothly. If you have any issues with your methylation process such as MTHFR, MTR, poor liver health, high stress, lack of sleep or something else causing methylation dysfunction then your creatine production goes down dramatically. This is a huge issue as creatine has notable effects on the brain 🧠 and cognition with research actually spanning back multiple years. The primary way it is believed to influence brain function is through its role in energy metabolism. Creatine aids in the formation of ATP, which is key for cognitive function, whilst also offering neuroprotection to certain conditions. We (Muhdo Health) decided to check this premise by analysing our dataset of creatine monohydrate users (>12m) between the ages of 30-60 (n=298) against a cohort of non-supplement users of the same age bracket (n=761) utilising our memory age DNA methylation clock. Surprisingly the mean of two key genes in the algorithm showed significant (p=1.65 × 10-34) hypomethylation which we indicate as superior cognitive ageing. These genes were: SLC25A43 and TMLHE Our calculations show that by taking creatine monohydrate consistently for a year or over you may reduce memory age by -6.2 years on average (mean). With our accelerated memory age being correlated with cognitive disease and subjective memory loss we would consider creatine a potential staple/essential nutrient Our advice, is to buy yourself some creatine asap and take a longevity dose of 5-10 grams each day!

𝐋𝐢𝐯𝐞 𝐜𝐨𝐥𝐝🥶, 𝐝𝐢𝐞 𝐨𝐥𝐝? 𝐋𝐨𝐰𝐞𝐫 𝐛𝐨𝐝𝐲 𝐭𝐞𝐦𝐩𝐞𝐫𝐚𝐭𝐮𝐫𝐞 𝐥𝐢𝐧𝐤𝐞𝐝 𝐭𝐨 𝐚 𝐥𝐨𝐧𝐠𝐞𝐫 𝐥𝐢𝐟𝐞.🧬👵🏽 As we are now heading into autumn here in the UK, and the weather becomes a bit chiller, it might not be such a bad thing if you’re looking to improve your longevity. It could be as easy as turning your heating down slightly! A recent study suggests that a lower body temperature 🥶may play a bigger role in lifespan than we first thought. An international research team explored the link between the saying " 𝘭𝘪𝘷𝘦 𝘧𝘢𝘴𝘵, 𝘥𝘪𝘦 𝘺𝘰𝘶𝘯𝘨," which often refers to people living risky lives and dying ☠️ earlier. In biological terms, it reflects animals 🐭 with a higher metabolic rate typically having shorter lifespans, as they burn through energy faster. However, the relationship between metabolism and longevity is more complex. For instance, calorie-restricted diets slow metabolism and are often associated with increased lifespan, while exercise 🏋️♂️boosts metabolism yet is still linked to longer life. So, what’s the true key to longevity? Researchers believe the answer lies in how changes in metabolism affect body temperature. Generally, a slower metabolism results in lower body 🥶temperature. In their study, scientists tested this by adjusting the metabolism and body temperature of mice 🐭and hamsters, increasing body temperature while reducing metabolism, to see how these factors influenced longevity. “We found that exposing the rodents to these conditions shortened their lifespans. Lower metabolism didn’t lengthen their lives, but higher temperatures shortened it,” says Professor John R. Speakman from the Shenzhen Institute of Advanced Technology in a media release. Stay cool🥶, live longer In the next step of the study, researchers used small fans to blow cool air over the animals living the high temps. Although this didn’t change their metabolism, researchers say it prevented the mice 🐭and hamsters from having a high body temperature. The study authors conclude that body temperature appears to have a much more important role in determining lifespan than metabolic rate” Gene 🧬PPARgC1A is a master regulator of a number of metabolic pathways in skeletal muscle, adipose tissue, pancreas and liver, which is strongly induced by cold exposure. It plays a critical role in the maintenance of glucose, lipid, and energy homeostasis, is a co-activator of antioxidant genes 🧬and is a master regulator of mitochondrial function and mitochondrial gene expression. It also plays a central role in regulating genes 🧬involved in cellular energy metabolism, and blood pressure regulation, cellular cholesterol homeostasis, adaptive thermogenesis and the development of obesity, and is involved in the regulation of both carbohydrate and lipid metabolism. So, perhaps take a leaf out of the Iceman 🥶Wim Hof’s book and take a cold shower in the morning to improve your longevity?🧬

𝐋𝐨𝐰 𝐎𝐦𝐞𝐠𝐚-3 𝐡𝐚𝐬 𝐭𝐡𝐞 𝐬𝐚𝐦𝐞 𝐫𝐢𝐬𝐤 𝐚𝐬 𝐒𝐦𝐨𝐤𝐢𝐧𝐠? 𝐍𝐄𝐖 𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡 A recent study from the well-known Framingham Heart Study found that a low Omega-3 levels could predict an early death just as well as key risk factors like cholesterol, blood pressure, and smoking. The Framingham Heart Study is one of the world's longest-running studies on cardiovascular disease. Its research led to the creation of the Framingham Risk Score, which uses eight standard factors to determine a person's risk for heart disease. This new finding adds a low Omega-3 Index to that list of powerful predictors, putting it in the same category as smoking and high blood pressure. 𝐌𝐨𝐫𝐭𝐚𝐥𝐢𝐭𝐲 𝐑𝐢𝐬𝐤: Low omega-3 levels are associated with the same increased risk of all-cause mortality as being a smoker. 𝐋𝐨𝐧𝐠𝐞𝐯𝐢𝐭𝐲: Research shows that people with the lowest Omega-3 index have a life expectancy that is, on average, five years shorter than those with the highest levels. Omega 3 deficiency is a serious and preventable risk factor for premature death, on par with smoking. While Smoking is obviously extremely harmful, a low Omega-3 index is a deficiency you can correct with diet and supplementation. Omega-3 fatty acids, specifically EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid), are polyunsaturated fats with extensive benefits for overall health. They are vital components of cell membranes throughout the body and are particularly concentrated in the brain and retina. EPA and DHA are well-known for their potent anti-inflammatory properties, which help to reduce chronic inflammation linked to various diseases, including heart disease and arthritis. DHA is critical for brain function, memory, and cognitive development, making it essential throughout all life stages, from infancy to old age. Both EPA and DHA also support cardiovascular health by helping to lower blood pressure, reduce triglyceride levels, and prevent the formation of blood clots. Given that the human body cannot produce these essential fats on its own, they must be obtained through the diet from sources such as fatty fish, or from supplements. 𝐇𝐨𝐰 𝐌𝐮𝐡𝐝𝐨𝐇𝐮𝐛 𝐎𝐦𝐞𝐠𝐚 3’𝐬 𝐀𝐫𝐞 𝐃𝐢𝐟𝐟𝐞𝐫𝐞𝐧𝐭 𝐓𝐨 𝐎𝐭𝐡𝐞𝐫𝐬? 𝐖𝐡𝐚𝐭’𝐬 𝐔𝐧𝐢𝐪𝐮𝐞? ·   𝐔𝐥𝐭𝐫𝐚-𝐏𝐮𝐫𝐞 made from Peruvian Anchovies, which are renowned for their exceptional purity, potency and bioavailability. ·    𝐌𝐚𝐱 𝐒𝐭𝐫𝐞𝐧𝐠𝐭𝐡 of the two main compounds EPA 1000mg and DHA 500mg per 2 soft gels. ·   𝐒𝐭𝐫𝐨𝐧𝐠𝐞𝐫 𝐭𝐡𝐚𝐧 𝐭𝐡𝐞 𝐦𝐚𝐣𝐨𝐫𝐢𝐭𝐲 𝐨𝐟 𝐎𝐦𝐞𝐠𝐚 3 𝐬𝐮𝐩𝐩𝐥𝐞𝐦𝐞𝐧𝐭𝐬. ·   𝐇𝐨𝐮𝐬𝐞𝐝 𝐢𝐧 𝐚 𝐏𝐚𝐭𝐞𝐧𝐭𝐞𝐝 𝐃𝐞𝐥𝐚𝐲𝐞𝐝 𝐑𝐞𝐥𝐞𝐚𝐬𝐞 𝐒𝐨𝐟𝐭 𝐆𝐞𝐥 ·   𝐍𝐨 𝐓𝐚𝐬𝐭𝐞 𝐨𝐟 𝐀𝐟𝐭𝐞𝐫 𝐓𝐚𝐬𝐭𝐞 ·   𝐍𝐨 𝐅𝐢𝐬𝐡𝐲 𝐁𝐮𝐫𝐩𝐬 ·   𝐍𝐨 𝐑𝐞𝐟𝐥𝐮𝐱 For further information please visit muhdohub.com The link to Dr Rhonda Patricks interview with Dr Bill Harris is in the comments…

A New 𝐆𝐄𝐍𝐄ration 𝐨𝐟 𝐥𝐨𝐧𝐠𝐞𝐯𝐢𝐭𝐲 𝐬𝐮𝐩𝐩𝐥𝐞𝐦𝐞𝐧𝐭𝐬 🧬 💊 Over the course of the last 8 years Muhdo Health has identified key nutrients such as vitamins, minerals and other special and unique compounds from well over 70,000 genetic and epigenetic samples. This has provided us with exceptional insight into the most common nutritional 🩸blood deficiencies, as well as genetic predispositions🧬 to specific inefficiencies. We have also seen how certain nutrients will have a positive effect on your Epigenetic Biological Age and improve the expression of certain longevity genes and pathways, such as to enhance DNA Methylation, Mitochondrial Health and Glutathione production. Based on this experience and after years of receiving customer enquiries about which brand or types of supplements to purchase, we decided it would be valuable to formulate and create our own range. 𝐦𝐮𝐡𝐝𝐨𝐡𝐮𝐛 🧬 We believed it would be exciting to initially launch with what we consider the most important nutrients/supplements, which are the most fundamental for everyone and relevant to all aspects of Health and Longevity. 𝐓𝐢𝐦𝐞𝐥𝐞𝐬𝐬 𝐕𝐢𝐭𝐚𝐦𝐢𝐧 𝐃 𝐓𝐫𝐢-𝐌𝐚𝐠𝐧𝐞𝐬𝐢𝐮𝐦 𝐁- 𝐕𝐢𝐭 𝐂𝐨𝐦𝐩𝐥𝐞𝐱 𝐎𝐦𝐞𝐠𝐚 3 𝐒𝐞𝐥𝐞𝐧𝐢𝐮𝐦 + The 𝐦𝐮𝐡𝐝𝐨𝐡𝐮𝐛 🧬products offer essential vitamins and minerals the often overlooked building blocks and forgotten foundations of our health, at a time when, in the "New Era" of health and longevity supplements 💊. Many companies, in their quest to appear unique, have neglected these fundamental elements of human biology. As unlocking the secrets to longevity, will always start with the basics and the nutrients you’ve forgotten” Vitamins and minerals are the essential nutrients that serve as the foundation for human health. They play critical roles in almost every biological process, from energy production and immune function 🦠to cellular repair and DNA 🧬synthesis. While certain compounds that are currently being touted as “Miracle’ supplements, such as NMN have gained attention for their potential to enhance cellular energy and combat ageing, but they only address specific pathways. In contrast, vitamin and mineral 🍎🥑🥕deficiencies affect a broader range of critical functions, making their effect on health and longevity far more significant. muhdohub. Better. Backed by Science. 🧬 For further information please visit www.muhdohub.com or email [email protected]