The Lancet Group

Organ transplantation can improve and save lives. 🫁 Yet, according to WHO, only 10% of the global need for transplants is being met. Critical challenges in access include: ➡️ organ shortages ➡️ immunosuppression risks ➡️ unequal access Despite these challenges, promising advances in organ preservation, genetic engineering, and precision immunosuppression offer hope. “The future is getting brighter for patients waiting for organ transplantation.” say authors of a new Series being presented at ESOT - European Society for Organ Transplantation. Find out more 👉 https://hubs.li/Q03vn_270 Alt: World map depicting the transplant rate per million people as reported by the GODT data, produced by the collaboration between WHO and the Spanish National Transplant Organisation.

Type 2 diabetes has increased in people under 40 years, with prevalence now exceeding 15% in some countries. In The Lancet, a new Series argues current approaches to early-onset type 2 diabetes are failing to meet the needs of younger people. “Besides straining already overburdened health systems, early-onset type 2 diabetes affects individuals during a key life stage, compounding the pressures of education, employment, and family planning, derailing young lives just as they are starting”, states a linked Editorial. Access the Series and Editorial in the comments 💬 Share with interested colleagues 🔄

📄 📆 We are pleased to invite you to the launch of The Lancet One Health Commission report—a comprehensive analysis that redefines how we think about health in a complex, interconnected world. This event brings together leading experts to discuss actionable recommendations for advancing One Health approaches. Join us on Thursday, July 17 at 12:00 BST/13:00 CET. Register today 👉 https://lnkd.in/edzKJzWU 🏷️ Universitetet i Oslo, Technical University of Munich, Center for Global Health (CGH) at TUM, TUM Klinikum Rechts der Isar, Bernhard Nocht Institute for Tropical Medicine, Kumasi Centre for Collaborative Research in Tropical Medicine (KCCR), Global Health and Infectious Diseases Group (GHID-KCCR)

In the past 50 years, childhood vaccines have saved an estimated 154 million lives* 💉🌎 We cannot afford to backtrack on this public health success 📉 For Gavi, the Vaccine Alliance’s pledging summit, Richard Horton reiterates the need to step up global immunisation efforts – to protect children, their families, and generations to come 👨👩👧👦 Full video: bit.ly/4lmW9Km #VaccinesSaveLives Explore related content from The Lancet in the comments 💬

In the past 50 years, routine childhood vaccines have saved an estimated 154 million lives.* Despite this significant health achievement, childhood vaccination coverage has stalled in recent decades, leaving millions of children at risk for vaccine-preventable diseases. ✅ Between 1980 and 2023, vaccine coverage doubled for diseases such as diphtheria, tetanus, whooping cough (pertussis), measles, polio, and tuberculosis. ✅ There was also a 75% global decline in the number of children who had never received a routine childhood vaccine. However, since 2010, progress has stalled or reversed in many countries. The COVID-19 pandemic has contributed to this, making access and uptake more challenging. Today, vaccine coverage varies widely across regions. 💡 To reach global immunisation targets and protect more children, the following strategies are essential: - Targeted and equitable immunisation approaches - Strengthening primary healthcare systems - Building resilience against vaccine misinformation - Understanding and addressing vaccine hesitancy For regional and country-specific data, read the #GBDStudy in full 👉 hubs.li/Q03tvZ240 -- 🖼️ Figure 1 below: Global and super-regional estimates of vaccine coverage over time. Mean global (A) and super-regional (B) coverage estimates for the target age population by year for each vaccine, with 95% uncertainty intervals. The dashed horizontal line indicates the coverage required to meet the IA2030 goal of 90% coverage for life-course vaccines. Find out more in the paper. *The global progress in vaccinating children against life-threatening diseases began with the World Health Organization’s establishment of the Expanded Programme on Immunization (EPI) in 1974. Access the study in the comments.

Early-onset type 2 diabetes, defined as diagnosis before age 40-years, is a rapidly escalating global health concern. Yet, it remains 👉 under-researched, 👉 undertreated, 👉 and poorly integrated into existing care models In a new Series, presented at #ADA25, authors synthesise emerging evidence, highlighting urgent research gaps, and call for population-level prevention and tailored care. Explore the Series ➡️ https://hubs.li/Q03s-0H30 Alt: World maps showing non-Communicable Disease Risk Factor Collaboration data showing the top 20 countries by number of people with diabetes age 20–39 years and by prevalence, and the top 20 countries with the largest percentage growth in prevalence of early-onset diabetes from 1991 to 2021.

Alzheimer’s disease is the main cause of dementia. It is quickly becoming one of the most expensive, lethal, and burdening diseases of this century. In general, neurological disorders are the leading cause of disease burden, affecting more than 3 billion people worldwide. To advance our mission of the best science for better lives, The Lancet has issued a call for papers for a dedicated issue on neurology. Learn more about the research we are looking for ⤵️ https://hubs.li/Q03spC2y0 💬 A Review on protective genetic variants against Alzheimer’s disease in the comments. The figure is from the Review: Differences between individuals susceptible or resilient to Alzheimer's disease.

💬 “Vaccines have done more to improve public health than any other medical intervention.” In The Lancet, a new Viewpoint focuses on cancer vaccines and the future of immunotherapy—analysing trials, different vaccine approaches, and how the next generation of cancer vaccines can help improve patient outcomes and quality of life. Read here: hubs.li/Q03sVVc-0 Tag colleagues who would find this Viewpoint interesting in the comments 👇 Figure: Types of therapeutic cancer vaccines. APCs=antigen-presenting cells. Full figure description in the paper.

❓ Missed the live session? The Lancet Primary Care's webinar is now available to watch on-demand. Join Editor-in-Chief Yaiza del Pozo Martín, and Senior Editors Jessica Smith and Lauren Southwell as they walk you through: ✔️ The aims and scope of The Lancet Primary Care ✔️ What they're looking for in submissions ✔️ How to best prepare your manuscript for publication As a fully open access journal, The Lancet Primary Care is dedicated to publishing impactful research across the full spectrum of primary care—from public health and prevention to mental health, infectious diseases, reproductive health, and more. Whether you're a first-time author or a returning contributor to The Lancet Group, this webinar offers valuable insights to help you navigate the submission process with confidence. ▶️ Watch on-demand now: https://hubs.li/Q03rflZf0 #PrimaryCare #MedicalPublishing #AcademicResearch #LancetPrimaryCare

Dear All- The Lancet's NY office is still looking for a Senior Editor. The ideal candidate has a PhD or MD, sound experience of research, human subjects ethics, and some editorial experience. They would be a strong writer. They would feel comfortable and have the experience and ability to present papers in large editorial meetings. They would be interested in growing into a role that offers the incredible opportunity to guide Lancet Commissions, paper Series, and to commission content. They would be excited about medical publishing and also the field of pre-prints. They believe in the mission of peer reviewed clinical research. If you are serious about applying, please feel free to DM me. For more see: https://lnkd.in/eaw-gMjf