Wellcome Trust

This is mitochondrial donation, the result of 30 years of research by teams at Newcastle University and The Newcastle Upon Tyne Hospitals NHS Foundation Trust. It reduces the risk of a rare inherited condition caused by faults in mitochondrial DNA. Mitochondria are like batteries powering our cells. If they’re faulty, the results can be severe. So far, eight healthy babies have been born thanks to the treatment. And it’s giving hope to families who have experienced the condition. Learn more about the impact ⤵️ https://lnkd.in/enDds6-j

Global action is essential to tackle antimicrobial resistance (AMR) – one of our greatest public health threats. That’s why we’re supporting CAMO-Net (Centres for Antimicrobial Optimisation Network), a research collaboration between institutions around the world. The network’s goal is to help address AMR through interventions and practices that matter to communities most affected. In our latest Wellcome Guest Lecture, CAMO-Net’s Alison Holmes, Senjuti Saha and Andrew Kambugu discuss how it all works and what they’re doing in Uganda and Bangladesh to enable policy change. Watch to learn more ⤵️ https://lnkd.in/erwWtjJm

Synthetic genomics is the science of creating new, engineered organisms and cells designed to do specific things. There’s excitement about this emerging field, which could offer a deeper understanding of human biology, including disease and health. What could the future of our health look like with synthetic genomics? Read our explainer to find out ⤵️ https://lnkd.in/eHaZBHCS

Power dynamics impact healthcare. For example, when you walk into a hospital, doctors might hold the most power. But professional dynamics are only one part of it. We also carry our identities with us, like our gender, race, ethnicity or migration status. These identities affect someone’s power and influence in any given situation, shaping their experience of healthcare. Inevitably, this impacts how we address urgent health challenges like antimicrobial resistance (AMR). In our latest ‘Behind the Research’ newsletter, Esmita Charani from the University of Cape Town explains the intersectional nature of AMR. She also shares the value of using research to find opportunities to improve healthcare ⤵️

I’m just leaving Brasília after a fantastic few days at the 2025 Global Conference on Climate and Health, and there’s a real sense of momentum as the world looks ahead to COP30 in Belém. I’ve also had the pleasure of speaking with #ScienceArena about why this year represents a powerful opportunity to put health at the centre of global climate action. We’re already seeing how climate change affects the lives of people through their health, and there is so much we must do. In our conversation, we explored:   ·       How science can drive locally led, evidence-based policy; ·      The growing need for tools that predict and prevent disease outbreaks; ·      The power of ethical, inclusive research networks rooted in communities.   As host of COP30, Brazil has a unique opportunity to lead a global response on the impact of climate change on health. By putting people’s health and wellbeing at the heart of climate action, we can create solutions that are not just effective, but are also fair, sustainable, and informed by those most affected. You can read the full interview here: https://lnkd.in/d5UWE9sE p.s. it’s been a while since I look as young as this!

Eight healthy babies have been born in the UK thanks to an IVF treatment that Professor Doug Turnbull and others pioneered over many years. What inspired Doug to pursue this impactful work? “Simply seeing patients in the clinic,” he says. Watch to learn more about the results of Doug’s research on mitochondrial disease, which made recent headline news, and what made this work possible.

Are you looking for mental health research funding? We’re supporting teams to accelerate the evaluation and roll out of social or psychological interventions for anxiety, depression and psychosis in young people. 💡 Why are we funding this? Social and psychological interventions have the potential to play a crucial role in early intervention for young people. However, there is limited understanding of which interventions are effective in real-world settings — and how best to implement and scale them. This knowledge gap limits the availability of evidence-based treatments, particularly in low-resource settings. 👥 Who can apply? We’re looking for diverse and interdisciplinary teams. The research itself must take place in the UK and/or low- or middle- income countries. To apply for this award, your team must: • be led by an experienced researcher • include at least one early career researcher as a coapplicant • include both researchers and implementation partners • meaningfully engage lived experience experts in multiple aspects of the research ✍️ How do I apply? Applications close 11 November. Learn more about the funding, application process and who can apply on our website: https://lnkd.in/e_sb-fsv

Our new mental health funding award is open for applications! We’re supporting teams to accelerate the evaluation and roll out of psychological or social interventions for anxiety, depression and psychosis in young people. Dr Kim Donoghue, Research Lead at Wellcome, explains more ⤵️ https://lnkd.in/e_sb-fsv

Would you use an AI therapist? The answer is rarely straightforward. In our newest explainer video, we speak to Professor Miranda Wolpert, Dr Joyce Nakatumba-Nabende and Shuranjeet Singh to learn more about the opportunities and risks of AI in mental health ⬇️ 🎥 https://lnkd.in/dNaahryF

The World Mosquito Program (WMP) prioritises community engagement everywhere it works. Their innovative approach involves infecting mosquitoes with Wolbachia bacteria to prevent the spread of deadly diseases like dengue and Zika. Working collaboratively not only improves public health, but also empowers communities to protect themselves sustainably. Around 13.3 million people have already been protected from mosquito-borne diseases thanks to this work. Hear more from Professor Scott O’Neill, founder of the World Mosquito Program, on our podcast, ‘When Science Finds A Way’: https://lnk.to/Ami475