Emulate, Inc.

🚨 Last chance to register for today’s live webinar! Join us today at 11:00 AM EDT / 8:00 AM PDT / 6:00 PM CET to hear Lorenzo Ferri MD PhD (McGill University) and Donald Ingber, M.D., Ph.D. (Wyss Institute at Harvard University) discuss how patient-derived Organ-Chips are transforming personalized medicine. Discover how this breakthrough approach predicts individual patient responses to cancer therapy — outperforming organoids and marking a major advancement for precision oncology. Don’t miss this opportunity to hear directly from two leaders shaping the future of human-relevant research! 🔗 Register now: https://lnkd.in/dXrb-Aqr #OrganChips #PersonalizedMedicine #CancerResearch #PrecisionOncology #NAMs

🎃 No tricks, just treats! The Emulate October Newsletter is now live—catch up on all the action from the last month and get a sneak peak at upcoming activities!

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⏰ Seats are filling fast for our upcoming webinar! Can patient-derived Organ-Chips predict how individual patients will respond to cancer therapy? A groundbreaking new study says yes — and it could redefine the future of personalized medicine. Join Lorenzo Ferri MD PhD (McGill University) and Donald Ingber, M.D., Ph.D. (Wyss Institute at Harvard University) as they discuss how Organ-on-a-Chip technology is enabling functional precision oncology and outperforming organoids in predicting therapeutic responses. 🎙️ Webinar: A New Paradigm for Personalized Cancer Medicine: Predicting Patient-Specific Therapeutic Responses with Organ-on-a-Chip Technology 🗓️ October 30th, 2025 at 11:00am EDT 🔗 Register now: https://lnkd.in/dXrb-Aqr #OrganChips #PersonalizedMedicine #CancerResearch #PrecisionOncology #MicrophysiologicalSystems #NAMs

Personalized medicine is only as powerful as the models we use to understand the patient. Genomics alone can’t always predict how a person will respond to a therapy. To truly personalize treatment, we need platforms that preserve the biology, mechanics, and microenvironment of the human body — even outside of it. That’s where Organ-on-a-Chip technology is changing the game. Our latest blog explores how researchers are using Organ-Chips with patient-derived samples to create the best possible “home away from home” for human tissues — enabling more predictive, physiologically accurate results. Read how Organ-Chips are advancing personalized medicine through three real-world examples: 🩸 Modeling clinical bone marrow toxicities and patient-specific pathophysiology 🧠 Recreating sporadic ALS on-chip using iPSC-derived motor neurons and a functional blood-brain-like barrier 🎯 Predicting chemotherapy response in esophageal adenocarcinoma with patient-derived tumor chips Together, these studies highlight how Organ-Chips can help researchers make the most of every patient sample — translating living human biology into actionable insights for discovery and precision therapy. Read the full story: https://lnkd.in/eiTKZTQS #OrganOnChip #PersonalizedMedicine #PrecisionMedicine #PatientDerivedModels #TranslationalResearch #MicrophysiologicalSystems #DrugDiscovery #NAMs

In the San Francisco area on Monday? 🌉 Join Gautam Mahajan, Ph.D., Principal Scientific Lead at Emulate, at the PBSS International Conference on Organoids, Tissue Bioengineering, and AI/ML Tools where he'll deliver a talk, “Implementation of a Human Liver-Chip and Decision-Making Criteria in Support of an IND Submission.” Gautam will discuss how the Emulate human Liver-Chip demonstrates higher sensitivity than hepatic spheroids and animal models for detecting drug-induced liver injury (DILI). He’ll highlight how this powerful NAM (New Approach Methodology) can be applied in preclinical development to support IND submissions—aligning with the FDA’s evolving roadmap for reducing animal studies in drug discovery. 📍 Event: PBSS International – Organoids, Tissue Bioengineering & AI/ML Tools 📅 Date: October 20, 2025 🕐 Time: 1:40 p.m. PDT 📍 Location: San Francisco, CA We hope to see you there! #PBSS #NAMs #OrganOnChip #LiverChip #DrugDevelopment #RegulatoryScience #Toxicology #PreclinicalTesting

🌍 Emulate is headed to Liverpool! Join Asli Akidil, Senior Scientific Lead at Emulate, at ELRIG Drug Discovery 2025 on October 21st at 4:30 p.m. for her presentation, “A Developer’s Journey Towards Regulatory Qualification of a Drug Discovery Tool.” Asli will share how Organ-on-a-Chip technology—including the Emulate Liver-Chip—can improve preclinical safety testing and reduce costly drug attrition. She’ll also walk through the Liver-Chip’s journey toward regulatory qualification through the U.S. FDA’s ISTAND program, paving the way for broader acceptance of innovative drug discovery tools. 📍 Track: In vitro and in silico models for sustainable drug discovery 📅 Date: October 21 🕠 Time: 4:30 p.m. 📍 Location: Liverpool, UK We hope to see you there! #ELRIG #DrugDiscovery2025 #OrganOnChip #LiverChip #PreclinicalTesting #RegulatoryScience #DrugDevelopment #NAMs

🚨 A breakthrough moment for personalized medicine: Until now, predicting how individual patients will respond to cancer treatment has remained one of precision oncology’s biggest challenges. A new study co-led by Lorenzo Ferri MD PhD (McGill University) and Donald Ingber, M.D., Ph.D. (Wyss Institute at Harvard University) demonstrates a powerful new solution: patient-derived Organ-Chips that accurately forecast each patient’s therapeutic response — outperforming organoids and setting a new standard for personalized cancer research. Join us on October 30th for a live webinar where Dr. Ferri will present these groundbreaking findings, followed by a discussion and Q&A with Dr. Ingber. Together, they’ll explore how this approach is transforming personalized medicine and redefining what’s possible in functional precision oncology. 🔬 Webinar: A New Paradigm for Personalized Cancer Medicine: Predicting Patient-Specific Therapeutic Responses with Organ-on-a-Chip Technology 🗓️ October 30th, 2025 at 11:00 am EDT 🎙️ Speakers: Dr. Lorenzo Ferri & Dr. Donald Ingber 👉 Register now: https://lnkd.in/dXrb-Aqr #OrganChips #PersonalizedMedicine #PrecisionOncology #CancerResearch #MicrophysiologicalSystems #NAMs

NASA - National Aeronautics and Space Administration has been sending animals to space for years to study how space travel affects them and extrapolate the effects on humans. Now, there might be a better way.   The next lunar mission will include Organ Chips provided by Emulate, Inc. as part of the AVATAR experiment. A similar batch of chips will remain on Earth as a control, and by comparing the two, researchers can better understand the effects of microgravity and space radiation levels inside the Orion capsule.    This proof-of-concept study will determine if the Chips can be used to accurately determine bone marrow response in astronauts. If it works, this method holds enormous potential in better understanding the impact of space travel on the human body, even comparing groups by factors such as age.    I am proud to see Organ Chips travel to this new frontier and excited to continue finding new and innovative ways to use this technology. https://lnkd.in/ewSTRiZA