Hyalex Orthopaedics Inc.

Hyalex Orthopaedics Inc.is excited to share that the Initial Results of the Hyalex Freestyle™ Knee Implant First-in-Human Clinical Studies will be presented by Dr. Sabrina Strickland, MD at the ICRS - International Cartilage Regeneration & Joint Preservation Society Congress on Monday, October 13, 2025, at 16:10-16:20 EST. In the Free Paper Session, "Fixation & Integration," beginning at 15:45 EST. Dr. Strickland will present an abstract titled, "First-in-human Study Of A Synthetic Cartilage Implant To Treat Painful Knee Cartilage Lesions,"  showing preliminary results suggesting that immediate restoration of the knee condyle joint surface with the Hyalex Freestyle Knee Implant can relieve pain and return function in a wide range of patients suffering from knee osteochondral lesions. Thank you to our investigators; Sabrina Strickland, Andreas Gomoll, Dennis Crawford MD, PhD, Deryk Jones, Marcin E. Domzalski, Urszula Zdanowicz and Scott Hacker MD for all your support throughout this groundbreaking journey. #ICRS2025 #CartilageScience #CartilageRepair #medtech #MassDevice #orthopedics

We are excited to share that the Initial Results of the Hyalex Orthopaedics Inc. Freestyle™ Knee Implant First-in-Human Clinical Studies will be presented by Dr. Sabrina Strickland at the ICRS - International Cartilage Regeneration & Joint Preservation Society Congress on Monday, October 13, 2025, at 16:10-16:20. In a paper titled, "First-in-human Study Of A Synthetic Cartilage Implant To Treat Painful Knee Cartilage Lesions," preliminary results suggest that immediate restoration of the knee condyle joint surface with the Hyalex Freestyle Knee Implant can relieve pain and return function in a wide range of patients suffering from knee osteochondral lesions. Thank you to our investigators; Sabrina Strickland, @Andreas Gomoll, Dennis Crawford MD, PhD, Deryk Jones, Marcin Domzalski, Urszula Zdanowicz and Scott Hacker MD for all your support throughout this groundbreaking journey. https://lnkd.in/duEFV4sJ #ICRS2025 #CartilageScience #CartilageRepair #MedTech #MedDevice #JointPreservation #ClinicalResearch

We are excited to share that the Initial Results of the Hyalex Orthopaedics Inc. Freestyle™ Knee Implant First-in-Human Clinical Studies will be presented by Dr. Sabrina Strickland at the ICRS - International Cartilage Regeneration & Joint Preservation Society Congress on Monday, October 13, 2025, at 16:10-16:20. In a paper titled, "First-in-human Study Of A Synthetic Cartilage Implant To Treat Painful Knee Cartilage Lesions," preliminary results suggest that immediate restoration of the knee condyle joint surface with the Hyalex Freestyle Knee Implant can relieve pain and return function in a wide range of patients suffering from knee osteochondral lesions. Thank you to our investigators; Sabrina Strickland, @Andreas Gomoll, Dennis Crawford MD, PhD, Deryk Jones, Marcin Domzalski, Urszula Zdanowicz and Scott Hacker MD for all your support throughout this groundbreaking journey. https://lnkd.in/duEFV4sJ #ICRS2025 #CartilageScience #CartilageRepair #MedTech #MedDevice #JointPreservation #ClinicalResearch

Early Results from Hyalex Orthopaedics Inc.'s First-in-Human Study Presented at ISAKOS 2025 I'm thrilled to share that Prof. Marcin Domzalski shared the early results from our first-in-human clinical studies of the Hyalex Freestyle™ Knee Implant during the Knee Cartilage session at ISAKOS Congress 2025 in Munich this week. The presentation, titled "First-in-Human Study of Biomimetic Synthetic Cartilage Implant To Treat Painful Knee Cartilage Lesions," revealed promising preliminary findings from both our Poland-based first-in-human trial and our U.S.-based Early Feasibility Study (EFS). 🔬 Key Highlights: • Early data suggests immediate restoration of joint surface with our biomimetic synthetic cartilage implant • Patients showing positive responses with quick pain relief and functional return • Joint-preserving technique precisely addresses specific pathology across a wide range of knee osteochondral lesions As Prof. Domzalski noted in his earlier assessments, "These are very promising results for cartilage patients at this stage of their treatment journey." This milestone represents a significant step forward in our mission to transform cartilage repair and help patients suffering from cartilage damage and early osteoarthritis regain their active lifestyles. With recent FDA approval expanding our Early Feasibility Study to a pivotal trial, we're excited about the potential to bring this cutting-edge technology to patients in need across the United States and Europe. Thank you to Prof. Domzalski, our investigators Sabrina Strickland, Andreas Gomoll, Dennis Crawford MD, PhD, Deryk Jones, Urszula Zdanowicz, Scott Hacker MD, the clinical teams, and all the patients who are part of this groundbreaking journey. #Innovation #OrthopedicSurgery #CartilageRepair #ClinicalTrials #ISAKOS2025 #MedicalDevice #KneeHealth #MassMedic

If you are looking for insight into Hyalex Orthopaedics Inc. technology, our clinical progress to date, and product roadmap, take a look at the recent LSI 2025 presentation from our CEO, Carl Vause. His presentation shares a snapshot of data from the Hyalex Early Feasibility and First-in-Human studies. Since this presentation in March 2025, these studies continued to enroll, and Hyalex has since received FDA approval to transition to the Freestyle knee pivotal trial. https://lnkd.in/ePHXQJEW #LSI #LSIAlumni #Medtech #Medicaldevices #orthopedics #cartilage #MassMedic

Great milestone for the Hyalex Orthopaedics Inc.team!

It's a great day in sunny San Diego. Congratulations to Scott Hacker MD, MD, and his team at Horizon Clinical Research in San Diego for enrolling their first Hyalex patient in our clinical study for knee cartilage repair. We’re very excited to work with Dr. Hacker and his team to continue enrolling patients in our clinical study. Check out our website to learn more about our off-the-shelf Hyalex synthetic cartilage technology: https://lnkd.in/e4qsPzFh Chris Cain Carl Vause #medicaldevice #orthopedics #LSIAlumni #medtech #jointpreservation #orthopedics #MassMedic Note: Investigational Device. Limited by Federal (or United States) law to investigational use.

Hyalex Highlight 🌟 Congratulations to Dr. Sabrina Strickland, MD, and Dr. Andreas Gomoll, MD at the Hospital for Special Surgery for enrolling their first Hyalex patients in our clinical study for knee cartilage repair! As we approach the end of 2024, we reflect on a year of great progress with our outstanding clinical partners. We’re honored to work with Dr. Gomoll and Dr. Strickland to continue enrolling knee patients in our clinical study.    Visit our website to learn more about our off-the-shelf synthetic cartilage technology: https://hyalex.com/ Note: Investigational Device. Limited by Federal (or United States) law to investigational use. Carl Vause Chris Cain #medicaldevice #medtech MassMEDIC #cartilage #orthopedics #HSS