How Biomedical Engineering solves medical problems

At Texas A&M School of Engineering Medicine, Dr. Chandler Benjamin is advancing the study of soft tissue mechanics to better understand how the body responds to stress and movement. By combining engineering principles with medical insight, his work is helping design safer devices, improve diagnostics, and prepare the next generation of physicianeers to innovate through hands-on research. 🔗: https://bit.ly/4huw5ME #tamuenmed #engineeringmedicine #biomedicalinnovation

Hunter Caroline Davies and Inga Kadish of the UAB Marnix E. Heersink School of Medicine have developed a digital Brain Atlas platform that displays detailed brain slices in multiple views, linking anatomy and pathology with interactive tools such as quizzes and MRI integration. The platform is accessible across various devices, providing a comprehensive, user-friendly tool for medical education. To learn more about this technology, please visit https://lnkd.in/d-7vHWhC or email us at ncantu@uab.edu.

🧪 Working together to advance standardization in biomechanics! Our latest publication in the Journal of Biomechanics is now online: “Community challenge towards consensus on characterization of biological tissue: C4Bio’s first findings” As part of the international C4Bio initiative, we joined 24 laboratories worldwide to investigate the mechanical characterization of biological tissues. 📊 The results are striking: Even under harmonized conditions, significant variability remains. This highlights the urgent need for reproducible, standardized methods—especially when biomechanical data serve as input for in silico medicine and computational simulations. 🔍 Our contribution: A first step toward reliable material data and “Good Simulation Practice.” The study offers valuable insights for researchers working with biological tissues, from fundamental science to medical device development. 📄 Read the full article: https://lnkd.in/ddt8A9ZE #C4Bio #Biomechanics #TissueCharacterization #InSilicoMedicine #Standardization #ResearchCollaboration #JournalOfBiomechanics #SimulationCredibility #OpenScience

🚀 Thrilled to share our latest publication! Our review article “Overview of Magnetic Hydrogel Fabrication, Its Basic Characteristics, and Potential Uses in Biomedical Engineering” has just been published in Bioengineering (MDPI) 🎉 Magnetic hydrogels are emerging as next-generation smart biomaterials — combining the responsiveness of magnetic nanoparticles with the versatility of hydrogels. In this work, we discuss the fabrication strategies, structural designs, properties, and biomedical applications (drug delivery, hyperthermia, MRI, wound healing, biosensing, and tissue engineering) of these exciting materials, along with the challenges and future directions for clinical translation. 🔗 Read the full paper here: https://lnkd.in/gSG26zwn #MagneticHydrogels #Biomaterials #Bioengineering #SmartMaterials #DrugDelivery #TissueEngineering #Nanotechnology

Exciting news from our team! 🎉 Our latest paper, “Integrating stent design and microstructural characterization to improve clinical outcomes of bioresorbable stents,” is now published and available online. The study is the result of a thorough, multidisciplinary collaboration between IQS Barcelona (Andres-Amador Garcia Granada, Jordi Martorell, Francesc Canalejo Codina), Universitat Politècnica de Catalunya (Marta Pegueroles Neyra) and Massachusetts Institute of Technology (Mercedes Balcells-Camps, Elazer Edelman). This work builds on the discovery of the failure mechanism that compromised earlier generations of polymeric stents — and turns that understanding into actionable design principles. By integrating mechanical design with microstructural analysis, we propose a new framework for creating bioresorbable stents that are not only safer and more reliable, but also capable of truly fulfilling the promise of polymeric technology. We believe this study marks an important step toward redefining how next-generation stents will be conceived, tested, and translated into the clinic in the coming years.

Highlighting Research Featuring the NeuralGlider Inserter! Justin Abbott, advised by Stuart Cogan, completed his doctoral dissertation in Biomedical Engineering, titled "Microelectrode Arrays for Chronic Neural Recording," at The University of Texas at Dallas. "We employed the NeuralGlider Cortical Neural Implant Inserter (Actuated Medical, Inc., USA) to facilitate implantation by providing axial vibration along the insertion path." Read more on this research here: https://bit.ly/47cX2zM Joseph Pancrazio, Shalini Prasad

Continuing to perform and publish novel research in the spine/orthopedic field is a unique and rewarding part of working at Exponent. This study was especially interesting, as we used our biomechanical tissue testing capabilities to answer questions about injury susceptibility in a specific patient population. We demonstrated just how much a "stiff" spine can influence its ability to bend and resistance to breaking. If you take one look at the side-by-side CT scans (and the study results), hopefully you'll be motivated to keep your spine flexible🧘and strong 🏋️. Happy to chat more about implications and lessons learned.

In a recent study published in the Journal of Applied Clinical Medical Physics, four commercial MR phantoms for image QA were compared on a 0.35 T MR-Linac using a clinical TRUFI sequence, across all gantry angles.   Two QUASAR phantoms a) 𝐌𝐑𝐈𝐃3𝐃 and b) 𝐌𝐑𝐠𝐑𝐓 𝐈𝐧𝐬𝐢𝐠𝐡𝐭 got utilized and proved essential in this study. Learn how these tools helped validate imaging accuracy and stability across rotations. ⬇️  👉 𝐒𝐰𝐢𝐩𝐞 𝐥𝐞𝐟𝐭 𝐭𝐨 𝐫𝐞𝐚𝐝 𝐭𝐡𝐞 𝐜𝐚𝐫𝐨𝐮𝐬𝐚𝐥 𝐛𝐞𝐥𝐨𝐰! 📖 𝐑𝐞𝐚𝐝 𝐭𝐡𝐞 𝐟𝐮𝐥𝐥 𝐬𝐭𝐮𝐝𝐲: https://lnkd.in/dbcJJxwi 📩 𝐖𝐚𝐧𝐭 𝐭𝐨 𝐥𝐞𝐚𝐫𝐧 𝐦𝐨𝐫𝐞 𝐨𝐫 𝐜𝐨𝐧𝐭𝐚𝐜𝐭 𝐮𝐬? https://lnkd.in/d-S3VVEd A big thank-you to the authors for their valuable research and contribution to advancing MR-guided radiotherapy - Mateb Al Khalifa, Tianjun Ma, William Song, @haya aljuaid, @Siyong kim! 👏

Bioengineering MDPI - From the Labs of Swiss Federal Institutes Of Technology/ETH Zurich 📚 GRGB rPPG: An Efficient Low-Complexity Remote Photoplethysmography-Based Algorithm for Heart Rate Estimation 🔗 https://brnw.ch/21wXaKE 📚 Quantification of the Phenomena Affecting Reflective Arterial Photoplethysmography 🔗 https://brnw.ch/21wXaKA 📚 PPG2ECGps: An End-to-End Subject-Specific Deep Neural Network Model for Electrocardiogram Reconstruction from Photoplethysmography Signals without Pulse Arrival Time Adjustments 🔗 https://brnw.ch/21wXaKC 📚 Co-Electrospun Poly(E-Caprolactone)/Zein Articular Cartilage Scaffolds 🔗 https://brnw.ch/21wXaKy 📚 First Insights in the Relationship between Lower Limb Anatomy and Back Squat Performance in Resistance-Trained Males and Females 🔗 https://brnw.ch/21wXaKF 📚 Localized Refractive Changes Induced by Symmetric and Progressive Asymmetric Intracorneal Ring Segments Assessed with a 3D Finite-Element Model 🔗 https://brnw.ch/21wXaKG 📚 The Three-Dimensional Body Center of Mass at the Workplace under Hypogravity 🔗 https://brnw.ch/21wXaKz 📚 Motion Analysis of the Wrist and Finger Joints in Sport Climbing 🔗 https://brnw.ch/21wXaKD 📚 Evaluation of Load on Cervical Disc Prosthesis by Imposing Complex Motion: Multiplanar Motion and Combined Rotational- Translational Motion🔗 https://brnw.ch/21wXaKB The publications can also be accessed via the QRs below. #MDPI #OpenAccess #Bioengineering #ETHZurich #Photoplethysmography #HeartRate #DeepNeuralNetwork #Electrocardiogram #Articular #Cartilage #Scaffolds #LowerLimb #FiniteElementModel #ThreeDimensional #Sport #Motion

I'm excited to share that two of my recent papers have been accepted in Medical Physics and Physics in Medicine and Biology. Simulation-guided transcranial ultrasound treatments rely on accurately determining the acoustic properties of skull bone, typically with pretreatment CT or MRI imaging. However, the clinical imaging resolution is limited (~0.5 mm isotropic) and cannot resolve bone microstructure. Our work demonstrates that this unresolved microstructure can lead to unaccounted-for variations in both attenuation and velocity. A key insight is that the parameter-estimation problem is fundamentally underdetermined, which helps explain why the literature reports a wide range of empirical relationships. In the discussion, we outline several future directions, including higher-resolution imaging approaches (such as photon-counting CT or deep-learning super-resolution) and the use of complementary guidance methods, such as Acoustic Radiation Force Imaging and MR-Hydrophone measurements. The broader message is clear: as a field, we need to carefully quantify and report uncertainty when relying on simulation-based treatment planning. Med. Physics Insertion Loss: https://lnkd.in/gpN27tqY PMB Speed of Sound: https://lnkd.in/gtsRfcW4 Utah BME Focused Ultrasound Foundation #FocusedUltrasound #Nueromodulation #kWave