ISPOR journal publishes study on cost savings and health benefits of semaglutide coverage

A major shift in how obesity is understood and treated. The new EASO framework moves beyond “weight loss” to managing obesity as a chronic, multi-system disease, recognising its mechanical, metabolic and inflammatory complications. Evidence places tirzepatide and semaglutide as first-line options, but the real innovation lies in personalised, evidence-based care guided by complications and clinical outcomes. The next challenge: integrating this science into accessible, equitable, and sustainable obesity services across health systems. #ObesityCare #EvidenceBasedMedicine #PublicHealth #ClinicalGovernance

𝐎𝐜𝐭𝐨𝐛𝐞𝐫 𝐢𝐬 𝐍𝐚𝐭𝐢𝐨𝐧𝐚𝐥 𝐋𝐢𝐯𝐞𝐫 𝐀𝐰𝐚𝐫𝐞𝐧𝐞𝐬𝐬 𝐌𝐨𝐧𝐭𝐡 — 𝐚𝐧𝐝 𝐭𝐡𝐞 𝐧𝐮𝐦𝐛𝐞𝐫𝐬 𝐬𝐡𝐨𝐮𝐥𝐝 𝐬𝐭𝐨𝐩 𝐚𝐥𝐥 𝐨𝐟 𝐮𝐬 𝐢𝐧 𝐨𝐮𝐫 𝐭𝐫𝐚𝐜𝐤𝐬. MASLD (Metabolic dysfunction-Associated Steatotic Liver Disease, formerly known as NAFLD) is present in 𝐮𝐩 𝐭𝐨 𝟕𝟓% 𝐨𝐟 𝐩𝐞𝐨𝐩𝐥𝐞 𝐰𝐡𝐨 𝐚𝐫𝐞 𝐨𝐯𝐞𝐫𝐰𝐞𝐢𝐠𝐡𝐭 𝐚𝐧𝐝 𝐦𝐨𝐫𝐞 𝐭𝐡𝐚𝐧 𝟗𝟎% 𝐨𝐟 𝐩𝐞𝐨𝐩𝐥𝐞 𝐥𝐢𝐯𝐢𝐧𝐠 𝐰𝐢𝐭𝐡 𝐨𝐛𝐞𝐬𝐢𝐭𝐲. Most don’t know they have it. There are often no symptoms—until it’s too late. The American Liver Foundation continues to advance early detection, research, and education. We are urgently focused on raising awareness that liver disease doesn’t discriminate. It affects people of all ages, backgrounds, and lifestyles—many who have never even considered their liver health. 𝐓𝐡𝐢𝐬 𝐦𝐨𝐧𝐭𝐡, 𝐈 𝐢𝐧𝐯𝐢𝐭𝐞 𝐲𝐨𝐮 𝐭𝐨 𝐭𝐚𝐤𝐞 𝐭𝐰𝐨 𝐬𝐢𝐦𝐩𝐥𝐞 𝐚𝐜𝐭𝐢𝐨𝐧𝐬: 1️⃣ Share this message to help others understand the growing prevalence of MASLD and the importance of early screening. 2️⃣ Learn more about liver health and MASLD through the American Liver Foundation’s trusted resources: https://lnkd.in/gip9rDCM Every share, every conversation, every moment of awareness matters. Because knowledge really can save lives. #LiverAwarenessMonth #AmericanLiverFoundation #MASLD #LiverHealth #PublicHealth #PreventiveCare #HealthcarePartners

  🫀 Your heart does more than beat—it connects everything.   With this week's #WorldHeartDay in mind, we’re shining a light on the most vital muscle in your body and the urgent need to protect it.   💙 But it’s not just about the heart. Obesity, type 2 diabetes, liver and kidney disease—they’re all part of the cardiovascular-kidney-metabolic (CKM) syndrome. And it’s costing lives. That’s why we’re highlighting the global burden of poor CKM health, which affects millions and increases cardiovascular risk across nearly every organ system.¹   🔍 Seeing the full picture means earlier detection, better care, and better outcomes. Our team at Novo Nordisk is committed to tackling this challenge through innovation. 🩺   #WorldHeartDay #CardiovascularHealth #CKMSyndrome #HealthInnovation #NovoNordisk ¹ Ndumele CE et al. Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association. Circulation. 2023;148(20):1606-1635. doi: 10.1161/CIR.0000000000001184.

Excellent work, World Health Organization on releasing the new consolidated guidelines for the prevention, diagnosis, and treatment of postpartum hemorrhage https://lnkd.in/ghr-p377 . These guidelines will play a vital role in accelerating efforts to reduce maternal morbidity and mortality, and support the achievement of sustainable development goals.

🫀 Your heart does more than beat—it connects everything.   With this week's #WorldHeartDay in mind, we’re shining a light on the most vital muscle in your body and the urgent need to protect it.   💙 But it’s not just about the heart. Obesity, type 2 diabetes, liver and kidney disease—they’re all part of the cardiovascular-kidney-metabolic (CKM) syndrome. And it’s costing lives. That’s why we’re highlighting the global burden of poor CKM health, which affects millions and increases cardiovascular risk across nearly every organ system.¹   🔍 Seeing the full picture means earlier detection, better care, and better outcomes. We are committed to tackling this challenge through innovative research and treatment solutions. 🩺   #WorldHeartDay #CardiovascularHealth #CKMSyndrome #HealthInnovation #NovoNordisk ¹ Ndumele CE et al. Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association. Circulation. 2023;148(20):1606-1635. doi: 10.1161/CIR.0000000000001184.

🫀 Your heart does more than beat—it connects everything.   With this week's #WorldHeartDay in mind, we’re shining a light on the most vital muscle in your body and the urgent need to protect it.   💙 But it’s not just about the heart. Obesity, type 2 diabetes, liver and kidney disease—they’re all part of the cardiovascular-kidney-metabolic (CKM) syndrome. And it’s costing lives. That’s why we’re highlighting the global burden of poor CKM health, which affects millions and increases cardiovascular risk across nearly every organ system.¹   🔍 Seeing the full picture means earlier detection, better care, and better outcomes. We are committed to tackling this challenge through innovative research and treatment solutions. 🩺   #WorldHeartDay #CardiovascularHealth #CKMSyndrome #HealthInnovation #NovoNordisk ¹ Ndumele CE et al. Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association. Circulation. 2023;148(20):1606-1635. doi: 10.1161/CIR.0000000000001184.

Early detection and prevention are key to addressing the global burden of non-communicable diseases (NCDs) and mental health. NCDs, such as cardiovascular, renal, and metabolic diseases, are deeply interconnected and often amplify one another, impacting over 1 billion people worldwide. Today, Shashank Deshpande advocated at #UNGA80 for integrated care models, early screening, and stronger primary healthcare systems. By investing in health early, we can improve outcomes for patients and create significant value for our societies.

CARE-IN-HEALTH: Advancing Cardiovascular Health Through Inflammation Resolution. Cardiovascular disease (CVD) is the leading cause of death and a major cause of morbidity in Europe, affecting over 49 million people and costing the EU economy €200 billion annually, despite major advances in prevention and treatment. The CARE-IN-HEALTH project (CArdiovascular REsolution of INflammation to promote HEALTH), funded by the EU Horizon Europe Programme European Commission, addresses a critical unmet medical need: chronic inflammation, a key driver in the transition from health to CVD. The dysregulated chronic inflammation behind atherosclerotic CVD (ASCVD) and its cardiovascular consequences are largely caused by a failure in the resolution of inflammation. Elevated levels of blood lipids (hyperlipidemia) are well documented risk factors for ASCVD. 🔬 Our focus: - Explore how appropriate lipid intake can promote the resolution of inflammation and support global prevention strategies. - Develop and test practical tools in real-life settings for healthcare systems and citizens to monitor inflammation and stay healthy. 🌍 Project Highlights: - 10 partners across 6 European countries - Coordination by Inserm under the direction of Professor Magnus Bäck CARE-IN-HEALTH is paving the way toward innovative, prevention-focused strategies for cardiovascular health and healthier ageing. 🔗 Learn more: care-in-health.eu #HorizonEurope #CAREINHEALTH #CardiovascularHealth #Inflammation #Resolution #PrecisionMedicine #HealthyAgeing #ResearchInnovation #Lipidomics #EUProjects

🫀 Your heart does more than beat—it connects everything.   With this week's #WorldHeartDay in mind, we’re shining a light on the most vital muscle in your body and the urgent need to protect it.   💙 But it’s not just about the heart. Obesity, type 2 diabetes, liver and kidney disease—they’re all part of the cardiovascular-kidney-metabolic (CKM) syndrome. And it’s costing lives. That’s why we’re highlighting the global burden of poor CKM health, which affects millions and increases cardiovascular risk across nearly every organ system.¹   🔍 Seeing the full picture means earlier detection, better care, and better outcomes. We are committed to tackling this challenge through innovative research and treatment solutions. 🩺 ¹ Ndumele CE et al. Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association. Circulation. 2023;148(20):1606-1635. doi: 10.1161/CIR.0000000000001184. #WorldHeartDay #CardiovascularHealth #CKMSyndrome #HealthInnovation #NovoNordisk

A study published in Diabetes Research and Clinical Practice found that severe gum disease is linked to significantly higher odds of advanced CKM syndrome. Researchers urged the integration of oral health into cardiometabolic care. Read more from DrBicuspid’s report here: https://bit.ly/42sCoKs #CKM