Quiz on Non - Mendelian Genetics

PIA JANE FAELDONEA DENTISTRY

Name: _Course:

Instructions: Email your quiz sheet at [email protected] with the header GENETICS –
last name e.g GENETICS - becares. Answers requiring calculations and punnet squares must be
handwritten, clearly legible and attached under each question. This will serve as 5 quizzes.
Deadline: March 26 at 8:30 pm.

Co dominance

1. In a certain fish, blue scales (BB) and red scales (bb) are co-dominant.
When a fish has the hybrid genotype, it has a patchwork of blue and red
scales. (Use the letter B)
a. What is the genotype for bluefish? BB
b. What is the genotype for redfish? bb
c. What is the genotype for patchwork fish? Bb

2. What happens if you breed a patchwork fish with a fish that only has Blue
Scales?
a. What is the probability of having fish with red scales?% 0
b. What is the probability of having fish with patch work scales? 50 %
B b
B BB Bb Genotype: ½ BB: ½ Bb
Phenotype: ½ Blue
3. Two patchwork fishB BB Bb are Patchwork
crossed. What is the probability that
they will have patchwork fish? 50 %
B b
BB Bb Genotype: ¼ Bb: ½ Bb: ¼ bb
B
Phenotype: ¼ Blue: ½ Patchwork:
b Bb bb ¼ Red

4. A roan bull (male) is mated with a white cow (female).What are the possible offspring?
Bull’s RW Cow’s genotype: WW
genotype:
Punnett Fill in the Punnett square and give the
square: phenotype percentages of this cross:
R W
50 %are White color
W RW 50 %are Roan color
WW

W RW
WW

5. Could Red offspring be born to a White cow mated with a Roan bull? No, this is
not possible
 IncompleteDominance

1. In snapdragons, flower color is controlled by incomplete dominance. The two alleles are
red
(R) And white (r). The heterozygous genotype is expressed pink.
(S)
a. What is the phenotype of a plant with the genotype RR? Red
b. What is the phenotype of a plant with the genotype Rr? Pink
c. What is the phenotype of a plant with the genotype rr? White

2. A pink-flowered plant is crossed with a white flowered plant. What

is the probability of producing a pink-flowered plant?

The genotype for the pink flower is Rr and the genotype

for the white flower is rr. This would lead to a 50%
chance of the offspring having a phenotype of pink

3. What cross will produce the most pink flowered plants? Show a Punnett square to
support your answer and explain.
Red flowers plus white flowers make 100% pink flowers.

R R

r R Rr
r
R Rr
r r

SpongeBob loves growing flowers for his pal Sandy! Her favorite
flowers, Poofkins, are found in red, blue, and purple. Use the
information provided and your knowledge of incomplete dominance to
complete each section below.

4. Write the correct genotype for each color if R represents a red gene
and B represents a blue gene. Red- RR Blue- BB Purple- BR

5. What would happen if SpongeBob crossed a Poofkin with red flowers

with a Poofkin with blue flowers. Complete the Punnett square to
determine the chances of each flower color.

a. Give the genotypes and phenotypes for the offspring. RB – purple B B

b. How many of the plants would have red flowers? 0% R BR BR
c. How many of the plants would have purple flowers? 100% R BR BR
d. How many of the plants would have blue flowers? 0%

6. What would happen if SpongeBob crossed two Poofkins with purple

flowers? Complete the Punnett square to show the probability for
each flower color.

a. Give the genotypes and phenotypes for the offspring. RR – red, BB – blue, RB -
purple
b. How many of the plants would have red flowers? 25%
c. How many of the plants would have purple flowers? 50% B R
d. How many of the plants would have blue flowers? 25% B BB BR
R BR RR
7. What would happen if SpongeBob crossed a Poofkin with purple
flowers with a Poofkin with blue flowers? Complete the Punnett
square to show the probability for plants with each flower color.

a. Give the genotypes and phenotypes for the offspring. BR – purple, BB - blue
b. If SpongeBob planted 100 seeds from this cross, how many should he
expect to have of each color? Purple – 50 plants, Blue – 50 plants,
B RedR
-0
B BB BR
B BB BR
Multiple Alleles

1. A woman sues for support of her child. She has Type A, her child is
Type O, the man Is B. Is the man the father? Explain.

2. A homozygous type B woman marries a heterozygous Type A man.

Show punnett square, genotypes and phenotypes.

3. A type B woman whose father was Type O marries a Type O man.

Show punnett square, genotypes and phenotypes.

4. A type A woman whose mother was Type B marries a Type B man whose
mother was Type A Show punnett square, genotypes and phenotypes.

5. A couple has a child with Type A blood. If one parent is Type O, what are
the possible genotypes of the other parent?

6. In rabbits, a series of multiple alleles controls coat color in the following

way: C is dominant to all other alleles and causes full color. The chinchilla
phenotype is due to the c ch allele, which is dominant to all alleles other
than C. The ch allele, dominant only to ca (albino), results in the
Himalayan coat color. Thus, the order of dominance is C> c ch>ch>ca.

For each of the following three cases, the phenotypes of the P1

generations of two crosses are shown, as well as the phenotype of one
member of the F1 generation.

For each case, determine

the genotypes of the P1
generation and the F1
offspring, and predict the
results of making each
indicated cross between
F1 individuals. Show
punnett squares.
Lethal Alleles

1. If factor “a” is lethal in the doubly recessive condition “aa”, then how
many offspring out of every 16 will survive from this cross: AaBb x AaBb?
Show punnett squares.

2. The tail less Manx phenotype (absence of tail in cats)is produced byan allele
that is lethal in the homozygote state. A single dose of the Manx allele, M L,
severely interferes with normal spinal development, resulting in absence of a
tail in the MLM heterozygote. Two tail less Manx cats were crossed? What kind
of progeny (children) are expected? Show punnett squares.

3. The recessive gene of anencephaly causes fetus death in homozygotes, while in

heterozygotes is manifested as spina bifida of different severity. Spina bifida is a
birth defect where there is in completes closing of the back bone and
membranes around the spinal cord. The condition often leads to death. A young
family needed consulting, because two of their children were stillborn with
anencephaly and one is alive, however has severe case of spina bifida. What is
the probability of healthy child birth? Show punnett squares.
 Sex Linked Inheritance

1. In fruit flies, the gene for white eyes is sex-linked recessive. (R) is red and(r)
is white. Cross a white-eyed female with a normal red-eyed male.
a. What percent of the males will have red
eyes? White eyes? Red eyes – 0% , white
eyes – 100%

b. What percent of the females will have red eyes?

Xr Xr Eyes? Red eyes – 100%, white eyes – 0%
X R R
X X r R
X X r
c.
c. What total percent of the offspring will be
Y X rY X rY white-eyed? 50%

d. What percent of the offspring will be carriers

of the white eye trait? 50% (only X R X r )

2. Using the same information as for question #1, cross a heterozygous red-
eyed female with a red-eyed male.

XR Xr
XR XR XR X R Xr
XRY X rY
Y
a. What are the genotypes of each parent?
X R Xr x XR Y
b. What fraction of the children will have red
eyes? ¾
c. What fraction of the children will have
white eyes? ¼
d. What fraction of the female children will
carry the white eyed trait? ½

3. In humans, hemophilia is a sex-linked recessive trait. If a female who is a

carrier for hemophilia marries a male with normal blood clotting, answer the
following questions.

XH Xh
XH X H XH X H Xh
XHY X hY
Y
a. What fraction of the female children will have
hemophilia? 0
b. What fraction of the female children will be carriers?
½
c. What fraction of the male children will have
normal blood clotting? ½
d. What fraction of the male children will be
carriers? 0 (males cannot be carries)
e. What fraction of the male children will have
hemophilia?1/2
4. A husband and wife have normal vision, although both of their fathers are
red–green color-blind, an inherited X-linked recessive condition.

What is the probability that their first child will be?

(a) A normal son? 25%

(b) A normal daughter? 50%

(c) A color-blind son? 25%

(d) A color-blind daughter? 0%

Because the wife has normal vision, but the trait is present
in her father, she will be heterozygous for that trait (Xx).
The husband does not show the trait and has only one x
chromosome, so he will a genotype of (XY). The new
offspring formed are XX, Xx and xY. Since both X’s are not
recessive in the daughter offspring, there is zero chance
that she will have the color-blind trait.

5. In humans, the A B O blood type is under the control of autosomal multiple

alleles.

Color blindness is a recessive X-linked trait. If two parents who are both type A
and have normal vision produce a son who is colorblind and is type O, what is
the probability that their next child will be a female who has normal vision and
is type O? Show punnett squares.
Probability NV = 1
Probability XX = ½
Probability type O = ¼
Answer = 1/8

6. In Drosophila, an X-linked recessive mutation, scalloped (sd), causes irregular

wing margins. Diagram the F1 and F2 results if(a) a scalloped female is
crossed with a normal male;(b)a scalloped male is crossed with a normal
female. Compare these results with those that would be obtained if the
scalloped gene were autosomal. Show punnett squares.