+
Behavioral Sciences Pharmacology
Shan Nanji
+ 2
Behavioral Science Pharmacology
Tricyclic Anti-Depressant's
n MOA:
n Blocks __________________
n Blocks __________________Receptors
n Interferes with AV Nodal Conduction
n Strongly __________________
n Anti Histamine
+ 3
Behavioral Science Pharmacology
Tricyclic Anti-Depressant's
n Amitriptyline – First line for chronic pain
n AMY-TRIPT-yline
n __________________ – Second line for bed wetting
n Nortriptyline – Least amount of effects on blood pressure
n NOR-triptyline
n Desipramine – Least amount of side effects over all
n DESI-pramine
n __________________ – Second line for OCD
+ 4
Behavioral Science Pharmacology
Tricyclic Anti-Depressant's
n S/E:
n Coma
n Cardiotoxicty
n Convulsions
+ 5
Behavioral Science Pharmacology
Stimulants:
n MOA:
n Blocks CC Reuptake
n Clinical Use:
n ADHD
n Narcolepsy
n Appetite Suppression
+ 6
Behavioral Science Pharmacology
Stimulants:
n S/E:
n Hypertension
n Tachycardia
n Anorexia
n Methylphenidate
n Dextroamphetamine
n Methamphetamine
+ 7
Behavioral Science Pharmacology
n SSRI’s
n Sertraline – PTSD
n SIR-traline
n Fluoxetine - Depression
n __________________ – Social Phobia
n DOC Pre-mature Ejaculation
n __________________ – Helps restore
memory post stroke
+ 8
Behavioral Science Pharmacology
n SSRI’s
n S/E:
n Anorgasmia!
n Serotonin Syndrome
n Hyperthermia
n Confusion
n Diarrhea
n Seizures
n Cardiovascular Collapse
+ 9
Behavioral Science Pharmacology
n SNRI’s
n Venlafaxine - Depression
n __________________– Depression
n More effect on NE
+ 10
Behavioral Science Pharmacology
n Maprotiline
n MOA:
n Blocks NE Reuptake
n S/E:
n Orthostatic HypOtension
n Sedation
+ 11
Behavioral Science Pharmacology
n Buproprion – For Smoking Cessation
n increases __________________
n Buspirone – For Anxiety
n BUS-pir-ON-e
n Benzodiazepines – Increase the ____________ of Cl- Channels
n __________________ – Shortest Acting
n Flourazepam – Longest Acting
n __________________ – Second line for absence seizures
n Triazolam – Puts you to sleep
n __________________ – Maintains sleep
Shan Nanji -
[email protected] + 12
Midazolam…
45 minutes anterograde amnesia…
+ 13
Sleep Pharm…
n Triazolam - Helps you go to sleep
n Tamazepam – Helps maintain sleep
n Which helps increase REM but can cause priapism?
- Trazodone
+ 14
Phenothiazines
n Low Potency
n __________________ – Decreases BP by blocking Alpha 1
n __________________ – Can cause iris pigmentation
+ 15
Phenothiazines
n High Potency
n Perchlorperazine – Anti-emetic in adults
n __________________– Anti-emetic in children
n Fluphenazine – Anti-psychotic, depot form
n Trifluoperazine
n S/E:
n Extrapyramidal System
+ 16
Antipsychotics: Butrephenons
n High Potency
n Haloperidol
+ 17
Antipsychotics: Butrephenons
n Atypicals
n __________________ – Gold standard
n S/E:
n Agranulocytosis
n Neutropenia
n Seizures
n Olanzapine
n S/E :
n __________________
+ 18
Antipsychotics: Butrephenons
n Atypicals
n __________________
n S/E:
n Increases PRL
n Quetiapine
n S/E:
n __________________
+ 19
Antipsychotics: Butrephenons
n Atypicals
n Ziprasidone
n S/E:
n Prolonged QT Possible
n Aripiprazole
n S/E:
+ 20
Monoamine Oxidase Inhibitors
“MAO-I”
n MOA:
n Block Mono-Amine Oxidase
n Increase Serotonin, NE, and Dopamine
n MAOi- A
n __________________
n Isocarboxacid
n __________________
+ 21
Monoamine Oxidase Inhibitors
“MAO-I”
n MAOi-B
n Selegeline
+ 22
Mood Stabilizers
n __________________
n First Blocks Na
n Then blocks Ca
n Fetal S/E:
n __________________
n __________________
n Bone Marrow Supression
+ 23
Mood Stabilizers
n Lithium
n Blocks __________________
n Fetal S/E:
n Epsteins Anomaly
n Right Atrium is __________________
n Left Heart __________________
n __________________ Blood Pressure
