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SERETIDE

This document summarizes information about the drug Seretide, which contains fluticasone propionate and salmeterol. Seretide is a combination drug used to treat reversible obstructive airways disease (ROAD) including asthma and chronic obstructive pulmonary disease (COPD). It works by selectively activating beta 2 adrenergic receptors to cause bronchodilation and block the release of allergic mediators. Recommended doses vary depending on the device, age, and condition being treated. Potential side effects include infections of the respiratory tract and mouth, as well as headaches, nausea, and muscle/bone pain. Nurses should monitor for allergic reactions and adverse effects, ensure proper use and storage of the

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615 views3 pages

SERETIDE

This document summarizes information about the drug Seretide, which contains fluticasone propionate and salmeterol. Seretide is a combination drug used to treat reversible obstructive airways disease (ROAD) including asthma and chronic obstructive pulmonary disease (COPD). It works by selectively activating beta 2 adrenergic receptors to cause bronchodilation and block the release of allergic mediators. Recommended doses vary depending on the device, age, and condition being treated. Potential side effects include infections of the respiratory tract and mouth, as well as headaches, nausea, and muscle/bone pain. Nurses should monitor for allergic reactions and adverse effects, ensure proper use and storage of the

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Tempo
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Drug Studies

Generic name: Fluticasone propionate and Salmeterol

Brand name: Seretide


Drug classification: Adrenergic
Suggested Dose: -DISKUS ROAD
 adult & adolescences greater than equal 12 yr: 1 inhalation of seretide 100,
250, or 500 BID
 Child greater than equal 4 yr: 1 inhalation of seretide 100 BID
 COPD ADULT: 1 inhalation of seretide 500 BID
-MDI ROAD
 adult & adolescences greater than equal 12yr: 2 inhalations of seretide 25/50
or 25/125 or 25/250 BID
 Child greater than equal 4 yr: 2 inhalation of seretide 25/50 BID
-COPD ADULT: 2 inhalations of seretide 25/125 or 25/250

Mechanism of action: Selectively activates beta 2 adrenergic receptors which results


in bronchodilation and block the release of allergic mediators from the mast cell in the
respiratory tract.
Indication: Regular treatment of reversible obstructive airways disease (ROAD)
including asthma where use combination therapy (bronchodilator and inhaled
corticosteroids) is appropriate, and COPD including chronic bronchitis & emphysema.
Contraindication: Hypersensitivity to sympathomimetics, tachydysrhythmias, severe
cardiac disease, monotherapy treatment of asthma, milk protein, primary treatment in
status asthmaticus, acute bronchospasm
Side effects & Adverse Effects:
 upper respiratory tract infections
 throat irritation
 hoarseness, voice changes, and trouble speaking
 thrush (fungal infections in your mouth or throat)
 bronchitis
 cough
 headache
 nausea and vomiting
 muscle and bone pain
 dizziness
 pneumonia

 increase in mucus production

 change in mucus color

 fever

 chills

 increased cough

 increased breathing problems


Nursing Intervention:
1. Assess patient for severe allergic reaction notify health care professional
immediately if these occur.
2. Follow Doctor’s prescription accordingly
3. Tell the patient to keep this drug in a dry place away from heat and sunlight.
4. Assess patient respiratory condition starting therapy
5. Inform the patient to not use drug if acute bronchospasm occurs.
6. Instruct the patient in how to use inhaler, to use it once daily at the same time
each day.
7. Asses for severe milk allergies; may be allergic to fluticasone vilanterol.
8. Inform patient of increased risk of pneumonia. Advise patient to notify health
care professional if fever, chills, change in sputum color, increased cough, or
increase in breathing problems occur.
9. Instruct the patient to rinse her mouth with water after each time you use your
Seretide inhaler.
10. Instruct the patient to use dust-proof covers on the mattress and pillows. Wash
the sheets and blankets on the bed once a week in very hot water.

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