OSTEOARTHRITIS
By: Vien Hardiyanti
Definition
• Osteoarthritis is a joint inflammation that results
from cartilage degeneration.
• Osteoarthritis can be caused by aging, heredity,
and injury from trauma or disease.
• The most common symptom of osteoarthritis is pain
in the affected joint(s) after repetitive use.
Epidemiology
Osteoarthritis(OA) is the most common joint
disease
OA of the knee joint is found in 70% of the
population over 60 years of age
Radiological evidence of OA can be found in over
90 % of the population
Type of Osteoarthritis
Idiopathic osteoarthritis
No identifiable cause
May be localized (confined to one or two joints)
or generalized (present in three or more joints)
Secondary osteoarthritis
Caused by an underlying condition: joint injury,
accumulation of calcium inside the joint, other
bone and joint conditions (eg, rheumatoid
arthritis), or a medical condition, such as diabetes
Fibrillation
Eburnation
Osteophytes
Subcondral cysts
Symptoms of osteoarthritis
Joint pain
Tenderness
Swelling
Stiffness
Locking
Sometimes an effusion
Reduced motion
Decreased movement can lead to pain, regional muscles
may atrophy, and ligaments may become more lax
Osteoarthritis
sites
Diagnosis
The diagnosis of osteoarthritis includes 3 major stages:
1. Patient history analysis
2. Physical examination
3. Imaging and Laboratory tests
Patient history analysis
The diagnosis begins with medical history, or information
about :
Patient’s health background
Conditions running in the family as some disorders are
inherited
Symptoms that prompts a patient to seek medical attention
Physical Examination
Based on the symptoms and the physical signs found
when examining the joints. The doctor checks for:
joint tenderness
creaking or grating (crepitus) sounds
bony swelling
excess fluid
reduced movement
joint instability
muscle thinning
Imaging and Laboratory Tests
Imaging Tests:
X-ray
Magnetic Resonance Imaging (MRI)
Arthroscopy
Laboratory Tests:
Blood tests
Joint Fluid Analysis/Joint aspiration
Imaging Tests
X-ray
Most useful test to confirm osteoarthritis
Cartilage doesn't show up on X-ray images
Cartilage loss is revealed by a narrowing of the
space between the bones in your joint
Bone spurs may be observed around a joint.
Patients may have X-ray evidence of osteoarthritis
before experiencing any symptoms
Detect calcium settling in joints
Magnetic resonance imaging
(MRI)
Uses radio waves and a strong magnetic field
to produce detailed images of bone and soft
tissues, including cartilage
Not commonly needed for diagnosis, but, may
help provide more information in complex cases
Expensive than X-ray
Does not involve radiation risk
Provides 2-D view resulting in better images
Arthroscopy
Minimally invasive surgical
procedure
An Arthroscope is inserted
into the joint area through
small incisions to find or even
repair damage done to the
joint
Reduced recovery time
High success rate due to less
damage done to connective
issue
Less scarring
Advantageous to athletes
Laboratory Tests
Blood test
No blood test for osteoarthritis as such
Suggested to rule out other types of arthritis e.g.
rheumatoid arthritis
Joint Fluid Analysis/Joint aspiration
A needle is used to draw fluid out of the affected joint
after the administration of anesthesia
Examination and testing of the fluid to determine
presence of inflammation , crystals or joint deterioration
Management: Algorithm
Lifestyle Modifications Acetaminophen
NSAIDs Celecoxib
Steroid Injections Opioids
Hyaluronan Injections
Surgical Referral
PRIMARY PREVENTION OF OA ??
Regular exercises
Weight control
Prevention of trauma
SYMPTOMATIC TREATMENT OF OA
Decrease of joint loading
- Weight control
- Splinting
- Walking sticks
Exercises
- Swimming
- Walking
- Strengthening
Patient education
Non-Pharmacologic Treatment of OA
Patient education
Weight loss (if overweight)
Aerobic exercise programs
Physical therapy
Range-of-motion exercises
Muscle-strengthening exercises
Assistive devices for ambulation
Appropriate footwear
Lateral-wedged insoles (for genu varum)
Bracing
Occupational therapy
Joint protection and energy conservation
PHARMACOLOGIC TREATMENT OF OA
Oral Systemic Medical Agents
- Analgesics (acetaminophen)
- NSAIDs
- Opioid analgesics
Intraarticular agents:
Hyaluronan
Glucocorticoids (effusion)
Topical agents
INDICATIONS OF SURGICAL
INTERVENTION
Severe joint pain,
resistant to conservative treatment methods
Limitation of daily living activities
Deformity, angular deviations, instability
Management: Surgical
When to Refer
Knee pain or functional status
has failed to improve with
non-operative management
Types of Procedures
Arthroscopic Irrigation
Arthroscopic Debridement
High Tibial Osteotomy
Partial Knee Arthroplasty
Total Knee Arthroplasty
Management: Surgical
Partial Knee Arthroplasty
Indication:
Unicompartmental arthritis
Ligaments spared
Increased ROM
Faster recovery
Prosthesis 10-yr survival: 84%
Management: Surgical
High Tibial Osteotomy
Indication:
Unicompartmental arthritis
Genu varus or valgus
Realign mechanical axis
Age < 60yo
< 15 degrees deformity19
Management: Surgical
Total Knee Arthroplasty
Indication:
Diffuse arthritis
Severe pain
Functional impairment
Pain relief > functional gain
ACL sacrificed
PCL also may be sacrificed
Prosthesis 10-yr survival: 90%
Thank you