Approach to the Patient
with Kidney Disease
JOHN RAY GONZALES MD
Hematuria
> 3 RBC /HPF
History
Hematuria on patients > 40 years old, consider it a sign of malignancy until proven otherwise
Bladder cancer
Hypercalciuria and hyperuricosuria are common in children
History of renal dysfunction in the family
Polycystic kidneys
Alport’s disease
Thin basement membrane disease
Other information
History of travel
Exposure to chemicals
Smoking history
Medication history
Recent infections
Nephritic Syndrome
Glomerular hematuria
Active urine sediments
History and review of systems
1. Glomerular hematuria
2. Tea-colored, dark brown, smoky urine
3. Foamy/frothy urine
4. Hearing or visual symptoms
Physical examination
Hypertension
Edema
Rash
Joint abnormality
Laboratory examination
1. Urinalysis
Proteinuria
RBC cast
Blood chem
CBC
BUN
Crea
ESR
CRP
Complement levels
ANA
ANCA
Nephrotic syndrome
1) High grade protenuria
2) Hypoalbuminemia
3) Lipiduria
4) Edema
5) Hyperlipidemia
History
DM
Viral infections
Medications
Autoimmune
Physical
examination
Edema
Ascites
Xanthoma
Nail findings
Laboratory exam
Urinalysis
Microscopy
Blood examination
Chest xray
Doppler of renal veins
Kidney biopsy
Obstructive uropathy
1) Acute
2) Sub-acute
3) Chronic
History and Review of Systems
Pain
Frequency
Urgency
Physical examination
Palpate the bladder
Laboratory test
Urinalysis
Creatinine
Imaging
Ultrasound
CT scan
Hypertension
History
Smoking
Alcohol use
Medications
Symptoms of target organ dysfunction
Symptoms of secondary hypertnsion
Investigation
Imaging
Chest xray
Doppler of renal vessels
Nephrolithiasis
History
Site of pain
Urinary symptoms
Diet
Medications
Occupation
Physical examination
Fever
Costovertebral angle tenderness
Laboratory
Urinalysis
◦ Urine pH
Uurine microscopy
Acute Kidney Injury
Chronic Kidney Disease
Urinary Tract Infection
Most common bacterial infection
Can be asymptomatic