Types of nerve injury and
diagnostic evaluation
Nagashree V
Classification
• Etiologic
• Anatomic
– Seddon’s classification
– Suderland’s calssification
Aetiologic
• Mechanical injury
• Crush injury
• Laceration
• Stretch
• thermal injury
• Infectious
• Malignancy
• Metabolic diseases
• Radiation
• Iatrogenic
• Chemical injury
• Occupational disorders
• Birth trauma
Grade 6- complex peripheral
nerve injury
Seddon’s classification
Diagnosis
• Clinical assessment
• Motor
– Muscle testing
– TINEL’S SIGN
• Sensory
– Two point discrimination
– Touch
– Pin Prick-Nocicepton
– Thermal discrimination
• Reflexes
• Autonomic
– Sweating, pilomotor response, Vasomotor parlysis
• Trophic changes
– Skin, Finger nails
– Osteoporosis
TINEL SIGN
SEMMENS WEINSTEIN MONOFILAMENT
THERMAL TESTING
TWO POINT DISCRIMINATION
REFLEXES
VASOMOTOR RESPONSE
TROPHIC CHANGES-SKIN
TROPHIC CHANGES- NAILS
MRC grading of sensory nerve dysfunction
MRC grading of muscle power
Electrophysiological
• Nerve Conduction Studies-NCV
– SNAP-Sensory Nerve Action Potential
– CMAP-Compound Motor Action Potential
• EMG- Electromyography
• SSEP-Somatosensory evoked potential
Motor nerve conduction study
Compound Motor Action Potential
Nerve Conduction
Velocity=PML-DML
Antidromic sensory nerve conduction study
Orthodromic sensory nerveconduction study
Sensory Nerve Action Potential
Electromyography
Motor Unit Action Potential
Normal
Chronic Nerve lesion
Early reinnervation -
Nascent units
Late reinnervation
Satellite Potential
SOMATOSENSORY EVOKED POTENTIAL
SUMMARY
• Conduction block
– Preserved sensory and motor nerve conduction in
distal segment
– Reduced amplitude depending on the severity
• Axonal block
– Reduced or Absent SNAP and CMAP
– Normal NCV
– Fibrillations in EMG