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Stochastic Theory of Aging - Edited

The document discusses biological theories of aging, which focus on physiological processes that change with age. It describes two divisions of biologic theories: stochastic and nonstochastic. Stochastic theories view aging as random events that accumulate over time, while nonstochastic theories see aging as predetermined phenomena. The document outlines five stochastic theories: free radical theory, somatic mutation theory, error theory, wear and tear theory, and cross-linkage theory. It provides details on the causes and management strategies for each theory.

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April Mae Magos Labrador
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371 views18 pages

Stochastic Theory of Aging - Edited

The document discusses biological theories of aging, which focus on physiological processes that change with age. It describes two divisions of biologic theories: stochastic and nonstochastic. Stochastic theories view aging as random events that accumulate over time, while nonstochastic theories see aging as predetermined phenomena. The document outlines five stochastic theories: free radical theory, somatic mutation theory, error theory, wear and tear theory, and cross-linkage theory. It provides details on the causes and management strategies for each theory.

Uploaded by

April Mae Magos Labrador
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as PPTX, PDF, TXT or read online on Scribd
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Theories of Aging: Biologic Type

STOCHASTIC
Reported by:
Burhan, Reem
Labrador, April Mae

Submitted to:
Pamela P. Pacada, RN, MAN
A Video Case Scenario:
Biological Theories of Aging:
➔ Concerned with physiologic
processes that change with aging.
Biologic Theories: 2 Divisions
❖ Stochastic: Explain aging as events that
occur randomly and accumulate over time.
➢ Episodic event

❖ Nonstochastic: View aging as certain


predetermined, timed phenomena.
➢ Predicted events happening
Stochastic Theories of Aging
➔ Effects of aging are primarily due to genetic
defects, development, environment, and the inborn
aging process.
➔ Entropy, in this context, refers to the tendency of
all matter to decay into a more random, less
ordered state.
➔ Aging is caused by small changes in the body over
time and the body's failure to restore the system
and mend the damages to the body.
Stochastic Theories has
5 components:
1. Free Radical Theory

2. Somatic Mutation Theory


3. Error (Orgel) Theory
4. Wear & Tear Theory
5. Cross-Linkage (Connective Tissue)
Theory
Free Radical Theory
Free Radical Theory
Exogenous Sources of Free Radicals:

❏ Tobacco smoke
❏ Pesticides
❏ Organic solvents
❏ Radiation
❏ Ozone
❏ Selected medications

Strategies to assist in delaying mitochondrial decay:

❏ Decrease calories in order to lower weight


❏ Maintain diet -- high in nutrients using antioxidants
❏ Avoid inflammation
❏ Minimized accumulation of metal in the body that
can trigger free radical reactions
Somatic Mutation Theory
Somatic Mutation Theory
Error causes:

❏ Radiation exposure
❏ Sunburn/ UV exposure
❏ Chromosomal abnormalities

Strategies to assist in delaying mitochondrial decay:

❏ Sunblock
❏ Avoid exposure to radiation
❏ Stem cell therapy
❏ Telomere
Error (Orgel) Theory
Error/Orgel Theory
Error causes:

❏ Radiation exposure
❏ Sunburn/ UV exposure
❏ Chromosomal abnormalities

Strategies to assist in delaying mitochondrial decay:

❏ Sunblock
❏ Avoid exposure to radiation
❏ Stem cell therapy
❏ Telomere
Wear & Tear Theory
Wear & Tear Theory
Causes of wear and tear:

❏ Strenuous exercise/ activity


❏ Effects of aging on adrenocorticosteroid activity
(ACTH)  lifelong exposure to STRESS.
❏ Exposure to radiation, toxins and UV

Management:

❏ Physiotherapy
❏ Diet -- high in nutrients and antioxidants
❏ Moderate exercise
❏ Cell repair/ stem cell therapy
Cross-Linkage (Connective Tissue) Theory
Cross-Linkage (Connective Tissue)
Theory
Management:

 Adequate fluid hydration


 Diet- low protein, high antioxidants and
calories.
 Exercise/ physiotherapy
What is the
difference?
Thank you!

Book References:
Gerontological Nursing (2010). Kristen L. Mauk

PDF References:
file:///C:/Users/Apple/Downloads/geriaricconsiderat
ionsinnursing-180217162057.pdf

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