Iontophoresis is a non-invasive technique that involves the transfer of drug ions through the skin using a constant direct current, enhancing the healing process. The effectiveness of iontophoresis relies on the selection of suitable ionic compounds, electrode placement, and factors such as treatment duration and current intensity. It is utilized for various conditions including pain, inflammation, scars, and edema with specific ions such as dexamethasone and lidocaine for therapeutic benefits.