This document discusses how to achieve high availability in PHP/MySQL applications using the mysqlnd driver. It describes different MySQL high availability configurations including master-slave replication, multi-master replication using Galera or NDB Cluster, and how mysqlnd's mysqlnd_ms plugin allows applications to connect to these clustered MySQL instances in a highly available manner by handling failover between nodes. The document provides examples of mysqlnd_ms connection configuration for both master-slave and multi-master setups.