Vincent Untz discusses running multiple hypervisors in an OpenStack cloud. OpenStack supports various hypervisors like KVM, Xen, Hyper-V, and VMware through different drivers. Running multiple hypervisors allows using each hypervisor's strengths and migrating workloads. It presents challenges for integration with OpenStack components and feature parity. SUSE Cloud provides tools to deploy and manage multiple hypervisors in a single OpenStack cloud.