The presentation discusses the limitations of relational database management systems (RDBMS) such as scalability and horizontal scaling methods like master-slave and sharding. It introduces NoSQL databases as alternatives that do not require fixed schemas and can manage large, semi-structured data, categorizing them into four types: key-value, column, document, and graph-based. The conclusion highlights the coexistence of NoSQL and RDBMS in modern applications, emphasizing a trend towards polyglot persistence.