NServiceBus is a lightweight messaging framework for .NET that helps make distributed systems more reliable, scalable, and extensible using a message-oriented architecture. It provides transaction management, automatic retries on failure, and supports various queues including MSMQ. Messages are sent asynchronously in the form of commands or events. Commands are processed by a single endpoint while events can be published to multiple subscribers. This improves reliability over a traditional request/response model. The document discusses how NServiceBus can be used to address issues like transaction management and data consistency when processing orders across multiple services in a distributed system.