The respiratory system has an upper respiratory tract and a lower respiratory tract. The upper tract includes the nose, nasal cavity, paranasal sinuses, and pharynx. The lower tract includes the larynx, trachea, bronchi, bronchioles, respiratory bronchioles, alveolar ducts, and alveoli. The respiratory system functions include breathing, gas exchange, gas conditioning, sound production, olfaction, and defense against pathogens. Key structures include the nasal cavity lined with ciliated epithelium, paranasal sinuses, pharyngeal regions, larynx, trachea, and branching bronchial tree ending in alveoli where gas exchange occurs.