Nutrition Support to the
Critically ill Patients
1Prof. Dr. RS Mehta, BPKIHS
2Prof. Dr. RS Mehta, BPKIHS
What is malnutrition?
“Malnutrition is a state of nutrition in which a
deficiency or excess (or imbalance) of energy,
protein and other nutrients cause measurable
adverse effects on tissue/body form (body
shape, size and composition) function and
clinical outcome.”
Elia, (2000)
3Prof. Dr. RS Mehta, BPKIHS
Normal diet:
The usual diet taken by individual in daily life.
4Prof. Dr. RS Mehta, BPKIHS
A healthy person's diet = balanced diet.
A healthy person's diet includes multitude of
vitamins, minerals and other beneficial nutrients.
• Water
• Carbohydrates
• Fats
• Proteins
• Vitamins
• Minerals
5Prof. Dr. RS Mehta, BPKIHS
The Six Essential Nutrients
Prof. Dr. RS Mehta, BPKIHS 6
Essential Minerals
• Calcium
• Phosphorus
• Iodine
• Iron
• Magnesium
• Zinc
• Selenium
The Food Pyramid
7Prof. Dr. RS Mehta, BPKIHS
Prof. Dr. RS Mehta, BPKIHS 8
Antioxidant: All-Stars
• Broccoli
• Canteloupe
• Carrot
• Kale
• Mango
• Pumpkin
• Red Pepper
• Spinach
• Strawberries
• Sweet potato
Definition of malnutrition
• A body mass index (BMI) <18.5kg/m
• Unintentional weight loss >10% in 3 – 6
months
• A BMI <20kg/m and unintentional weight loss
>5% in 3 – 6 months
9Prof. Dr. RS Mehta, BPKIHS
Why does malnutrition develop?
• Impaired intake
• Impaired digestion and absorption
• Altered nutritional requirements
• Excess nutrient losses
10Prof. Dr. RS Mehta, BPKIHS
Malnutrition
in
the critically ill
Hypermetabolism
Stress
Changes
in
substrate
utilisation
Exogeneous steroids Prolonged bed rest
Immobility
Poor intake Surgery
11Prof. Dr. RS Mehta, BPKIHS
Malnutrition
• Many people are malnourished prior to admission to
hospital
• People in hospital are at risk of becoming
malnourished or further malnourished
• Prevalence of malnutrition in hospital has been
quoted as 40% (McWhirter & Pennington, 1994)
• Up to 43% of patients in ICU are malnourished (Giner
et al, 1996)
12Prof. Dr. RS Mehta, BPKIHS
Consequences of malnutrition
• Weight loss
• Weakness and fatigue
• Impaired ventilatory drive
 DEATH
• Depression / apathy
• Poor wound healing
• Impaired immune function
Webb (1999), Garrad (1996)
13Prof. Dr. RS Mehta, BPKIHS
Why feed the critically ill?
• Provide nutritional substrates to meet protein
and energy requirements
• Help protect vital organs and reduce break
down of skeletal muscle
• To provide nutrients needed for repair and
healing of wounds and injuries
• To maintain gut barrier function
• To modulate stress response and improve
outcome
14Prof. Dr. RS Mehta, BPKIHS
Prof. Dr. RS Mehta, BPKIHS 15
Nutritional Assessment
• History – 10% weight loss or more suggests
protein malnutrition
• Exam – Weight/Ideal body weight (<85%
predicted), temporal muscle wasting,
anthropometrics
• Nutritional markers
-albumin
-haemoglobin
-urea
-creatinine
- glucose in blood
Prof. Dr. RS Mehta, BPKIHS 16
Body Mass Index (BMI) and Nutritional Status
BMI Nutritional Status
>30 kg/m2 Obese
>25–30 kg/m2 Overweight
20–25 kg/m2 Normal
<18.5 kg/m2 Moderate malnutrition
<16 kg/m2 Severe malnutrition
<13 kg/m2 Lethal in males
<11 kg/m2 Lethal in females
Checklist for malnutrition
• Illness
• Eating poorly
• Tooth loss or mouth pain
• Economic hardship
• Reduced social contact
• Multiple medicine
• Involuntary weight loss or gain
• Assistance in self care
• Elders above 80 yrs .
Prof. Dr. RS Mehta, BPKIHS 17
Basal energy expenditure
The basal energy expenditure is easily calculated
from the Harris-Benedict equation is :
For men:
• 66+(13.7 18ₓ w)+(5ₓH)-(6.8ₓA)
For women:
• 65.5+(9.6ₓw)+(1.8ₓH)-(4.7ₓ A)
W=weight in kg, H=height in centimeters,
A=age in years.
18Prof. Dr. RS Mehta, BPKIHS
Prof. Dr. RS Mehta, BPKIHS
Nutritional Therapy
• Healthy adult –
approx 25 kcal/kg/day, 1g protein/kg/day
• Pretty sick to moderately sick –
30 kcal/kg/day, 1.5g protein/kg/day
• Very sick –
35 kcal/kg/day, 2g protein/kg/day
• Very Very sick
- 40 kcal/kg/day, 2.5g protein/kg/day
Hospital diet
The treatment of a disease or disorder with a
special diet. Dietary prescriptions include:
1.clear liquid
2. full liquid diet
3.soft diet
Special Diets (low-residue, high-fiber, liberal
bland, fat-controlled, sodium-restricted).
Hospital diet
20Prof. Dr. RS Mehta, BPKIHS
• This diet should be completely free of
any solids, E.g. tea or coffee without
cream or milk, clear soup, filtered fruit
juices etc.
• Nutritionally inadequate, used for a very
short period of time .
• Full liquid diet should be given for all
acute conditions before diagnosis.
Liquid diet-clear
21Prof. Dr. RS Mehta, BPKIHS
Full liquid diet
• It consists of
Fruit juices
Soup
Milk
Curd
Ice-cream
Lassi
Custard
Prof. Dr. RS Mehta, BPKIHS 22
Contd…….
• Liquid diet is suitable for conditions:
Head Injuries, Gastroctomy Cases, Paralytic
Syndrome and other Conditions where the
patients are unable to swallow., First 24-48
hours in Caardiovascular Disorders and Post
Operative Cases , Severe Burns.
23Prof. Dr. RS Mehta, BPKIHS
Items for NG tube feeding
• Liquid diet
• Skimmed milk
• Skimmed milk powder.
• ICU diet.
• Strained fruit juice and vegetable soup.
• Egg powder.
• Sugar or molasses.
24Prof. Dr. RS Mehta, BPKIHS
25
N G Tube feeding esp.
1. Calories (sick): 30 cal/kg/24 hrs
eg. Pt. wt. 30 kg = 30x30 =900 K cal/24 hr
Idealy 1 cal. = 1 cc, hence = 900 cc
2. For severe sick( eg. Burn):
40 cal/kg/24 hr
In cal = fat 20-30% & CHO = 60-80 %
Extra Protein+ Vitamin + Minerals etc
Water: 2 ml/kg/hr (IV or Oral)
Prof. Dr. RS Mehta, BPKIHS
Churn diet/ blenderized diet in
BPKIHS
• Rice, dal and vegetables blended together
• Fruits, curd and fish can also be added
• Protein and other supplements provided
separately
26
Protocol in BPKIHS for enteral feeding
• Frequent mouth care.
• The nasal tape is changed as necessary
• Throat lozenges, an ice collar, chewing gum, or sucking on
hard candies (if permitted)
• Head end elevation- 45 degrees for 1 hour before, during and 1
hour after gastric feeding.
• Strict hand washing before handling the feeding formula and
equipment
• Do not Use excessive force when administering anything
27
• Do not Use cold water
• Residual monitored every 4 hours.
• Maintain adequate hydration by providing Water
(at least 2 L/day) every 4 to 6 hours and after
feedings and observe for signs of dehydration
• Proper storage of the formula- refrigerate diluted
or reconstitued formula and formula that contains
additives
28
To ensure patency and to decrease bacterial growth, 20
to 30 mL of water is administered
Before and after each dose of medication and each
tube feeding
After checking for gastric residuals and gastric pH
Every 4 to 6 hours with continuous feedings
If the tube feeding is discontinued for any reason
29
In case of tube occlusion
• Inject warm water and agitate with
syringe.
• If ineffective (dissolve 1 tablet
Violase with 1 tablet sodium
carbonate in 5 ml. Inject and clamp
for 5 minutes).
30
Guidelines for the administration for medications
via enteral feeding tube
• If possible administer the medication by mouth
• Use a liquid form of the medication if available
• If the medication can be crushed, crush it to a fine powder
and dissolve it in 30 ml of water
• Do not crush enteric coated or time released tablet or capsule
• Flush the tube with 30 ml of water before and after giving
each medication
• Do not mix multiple medication or give them together
• Do not deliver a medication into the small intestine if it must
be absorbed in the stomach such as sucralfate or antacids
• Hold feeding 1 or 2 hours before and after giving a
medication that might have drug nutrient interaction such as
phenytoin
31
Maintaining normal bowel elimination
Common problems
• Diarrhea (three or more times in 24 hours), commonly
due to feeding formula and medication like
acetaminophen, ferrous sulphate, metoclopramide, KCl,
Theophylline
• The dumping syndrome due to Zinc deficiency, rapid
distention of the jejunum when hypertonic solutions are
administered quickly (over 10 to 20 minutes)
• Malnutrition—due to decreased absorption
Management
• Adding 15 mg of zinc to the tube feeding every 24
hours
32
Indications for parenteral nutrition
• The main indication for parenteral nutrition is when the gut is
not functional and who is requiring complete bowel rest.
Examples of inadequate gut function might include:
• Bowel obstruction or suspected gut ischemia
• Some types/locations of gastrointestinal fistula
• Short bowel syndrome due to surgery
• Persistent severe diarrhea or significant malabsorption
• Persistent signs of significant gut dysmotility (a distended
and/or painful abdomen, persistent large gastric aspirates, no
bowel output)
• Some stages of ulcerative colitis
33
TOTAL PARENTERAL FEEDING
34Prof. Dr. RS Mehta, BPKIHS
35
Parenteral Nutrition
• 3 liters of fluid necessary to give enough
calories via TPN due to limitations on dextrose
content due to phlebitis risk.
• Dextrose administration should not exceed
3.5mg/kg/min to avoid metabolic
complications.
• Fats – Septic patients have decreased ability to
utilize dextrose, but use fats well
– Also prevents essential fatty acid deficiency
Prof. Dr. RS Mehta, BPKIHS
Indications of TPN:
• Intestinal obstruction, or surgery.
• Gastrointestinal fistula.
• When the bowel needs to rest : Crohn’s
disease, pancreatitis, ulcerative colitis.
• Prolonged diarrhoea in children.
• Severe burns, multiple fractures or severely
malnourished individuals.
36Prof. Dr. RS Mehta, BPKIHS
Content of TPN
• For an adult a standard TPN solution Content:
amino acids, fat emulsions, dextrose,
electrolytes, trace elements, vitamins and
additives.
• Calorie: 60% CHO, 20% protein and fat each.
37Prof. Dr. RS Mehta, BPKIHS
Recommended amount of
electrolytes per day
• Sodium 40-100 mmol or 1-2 mmol/kg
• Potassium 60-150 mmol or 1-2 mmol/kg
• Calcium 2.5-5 mmol
• Magnesium 4-12 mmol
• Phosphorus 10-30 mmol
• Chloride As needed to maintain acid-base
balance with acetate
38
Choice of nutrition regimen
• Parenteral nutrition infusions can be:
–Continuous (running 24 hours a day), cyclic
(running for a period of between 8 and 18
hours each day)
Or
–Intermittent (on some days only).
39
TPN
40Prof. Dr. RS Mehta, BPKIHS
Parenteral nutrition infusion rate
• Typical infusion rates vary between 40-
150mL/h, but cyclic infusions may be
delivered at rates as high as 300mL/h.
41
Stopping parenteral nutrition
• Close monitoring with hourly blood glucose testing, for several
hours
• Abruptly stopping parenteral nutrition cause a rebound
hypoglycemia in some patients due to ongoing action of insulin
• For patients with normal blood glucose levels who have not been
receiving insulin, the infusion can usually just be stopped.
• Those receiving insulin,-brief tapering regimen: ensure that insulin
infusions are ceased, that other insulin dosage is reviewed, and
then decrease the parenteral nutrition infusion rate by half for an
hour.
• Alternatively the parenteral nutrition can be replaced with a 10%
dextrose infusion at the same rate for an hour, before stopping
completely.
42
Role of nurse in care of patients with TPN
• Care of the vascular access site
• Physical management of the parenteral nutrition infusion and
the related equipment
• Training for the home parenteral nutrition
• Assistance for insertion of vascular access device
43
Prof. Dr. RS Mehta, BPKIHS
Complication
• Mechanical: occlusion, catheter removal,
improper rate, thromboses, pneumothorax.
• Infection: catheter related
• Metabolic: re-feeding syndrome,
hyperglycemia, fluid & electrolyte
disturbance
• Organic system: hepatobiliary
complication, respiratory, cardiovascular,
renal
44
45Prof. Dr. RS Mehta, BPKIHS
Separate container
46
Single, Double and Triple Bag: Carbohydrate, Lipid and Amino acid
Double-chamber bags
47
Triple-chamber bags
48
Available in solution
• Trade name: Addamel N
• Generic name: trace elements with selenium
and iodide
• Trade name: Intralipid
• Generic name: fat emulsion
• Trade name: Aminosyn
Generic name: parenteral nutrition solution
49
Enteral vs. Parenteral Nutrition
Enteral Parenteral
Advantages
-Physiological
-Simpler
-Cheaper
-No CVL required
-Less monitoring
-Less complication
Advantages
-Independent of GIT functions
Disadvantages
-Dependent on GIT functions
-Diarrhea
-Feed intolerance
-NG tube – malposition, sinusitis
-Pulmonary aspiration
Disadvantages
-Non physiological
-Requires venous access
-Higher risk of systemic infection
-Expensive
-More complication
50Prof. Dr. RS Mehta, BPKIHS
Enteral Parenteral
Complications
1. Mechanical
-GEReflux
-NG complication – oesophageal
perforation, throat injuries,
tracheal placement, blockage,
rupture oesophageal varices
2. Infection
-Sinusitis, otitis
-Pulmonary aspiration
-Feed contamination
3. GIT – nausea, vomit, diarrhea
4. Metabolic
-dehydration, hyperglycaemia
-electrolyte abnormality
-acid base imbalance
Complications
1. CVL related complication
2. Fluid overload
3. Hyperosmolar dehydration
syndrome – hyperglycaemia,
osmotic diuresis
4. Electrolytes imbalance
5. Metabolic acidosis
6. Hyperammonaemia
7. Deficiency Syndromes
8. Rebound hypoglycaemia – if
TPN stopped suddenly due to
high level endogenous insulin
9. Overfeeding syndrome.
51Prof. Dr. RS Mehta, BPKIHS
52
Nutrition for critically ill patients
Daily energy expenditure:
1. Basal energy expenditure ( BEE ):
amount of energy required for basal
metabolism. (during resting & fasting)
2. Resting energy expenditure ( REE):
When person is resting but not fasting.
BEE: 25 X weight in Kg.
REE: 1.2 x BEE
Prof. Dr. RS Mehta, BPKIHS
53
Fever: energy required = BEE X 1.1
For each oF rise, energy = BEE x 1.1 x 2
According to level of stress:
1. Mild: E. required: 1.2 x BEE
2. Moderate: E. required: 1.4 x BEE
3. Severe : E. required: 1.6 x BEE
Prof. Dr. RS Mehta, BPKIHS
54
• 70 % Energy is given by CHO
• 30 % Energy is given by Lipid
• Protein is not given for energy but only for
tissue development.
• Protein: 0.8-1 gm/kg body wt. (normal)
• If pt. is hyper-catabolism ( Fever, hyper-
thyrodism), then protein = 1.2 to 1.6 gm/kg
• Multivitamin in 5% Dextrose, if pt. on IVF and
NPO
Prof. Dr. RS Mehta, BPKIHS
SUMMARY
• Diet is the sum of food consumed by a person
or other organism. healthy person's diet =
balanced diet.
• A healthy person's diet includes multitude of
vitamins, minerals and other beneficial
nutrients. Different medical diseases
constitutes different meal patterns.
55Prof. Dr. RS Mehta, BPKIHS
Conclusion
• Do not forget about feeding
• Keep an eye on whether nutritional
targets are being met
• Speak to the surgeons and dietician
• Do not be reluctant to start PN in a
supplemental capacity
• Avoid hyperglycaemia
• Nutrition is often neglected
56Prof. Dr. RS Mehta, BPKIHS
57Prof. Dr. RS Mehta, BPKIHS
58Prof. Dr. RS Mehta, BPKIHS

4. nutrition support to critically ill in icu

  • 1.
    Nutrition Support tothe Critically ill Patients 1Prof. Dr. RS Mehta, BPKIHS
  • 2.
    2Prof. Dr. RSMehta, BPKIHS
  • 3.
    What is malnutrition? “Malnutritionis a state of nutrition in which a deficiency or excess (or imbalance) of energy, protein and other nutrients cause measurable adverse effects on tissue/body form (body shape, size and composition) function and clinical outcome.” Elia, (2000) 3Prof. Dr. RS Mehta, BPKIHS
  • 4.
    Normal diet: The usualdiet taken by individual in daily life. 4Prof. Dr. RS Mehta, BPKIHS A healthy person's diet = balanced diet. A healthy person's diet includes multitude of vitamins, minerals and other beneficial nutrients.
  • 5.
    • Water • Carbohydrates •Fats • Proteins • Vitamins • Minerals 5Prof. Dr. RS Mehta, BPKIHS The Six Essential Nutrients
  • 6.
    Prof. Dr. RSMehta, BPKIHS 6 Essential Minerals • Calcium • Phosphorus • Iodine • Iron • Magnesium • Zinc • Selenium
  • 7.
    The Food Pyramid 7Prof.Dr. RS Mehta, BPKIHS
  • 8.
    Prof. Dr. RSMehta, BPKIHS 8 Antioxidant: All-Stars • Broccoli • Canteloupe • Carrot • Kale • Mango • Pumpkin • Red Pepper • Spinach • Strawberries • Sweet potato
  • 9.
    Definition of malnutrition •A body mass index (BMI) <18.5kg/m • Unintentional weight loss >10% in 3 – 6 months • A BMI <20kg/m and unintentional weight loss >5% in 3 – 6 months 9Prof. Dr. RS Mehta, BPKIHS
  • 10.
    Why does malnutritiondevelop? • Impaired intake • Impaired digestion and absorption • Altered nutritional requirements • Excess nutrient losses 10Prof. Dr. RS Mehta, BPKIHS
  • 11.
    Malnutrition in the critically ill Hypermetabolism Stress Changes in substrate utilisation Exogeneoussteroids Prolonged bed rest Immobility Poor intake Surgery 11Prof. Dr. RS Mehta, BPKIHS
  • 12.
    Malnutrition • Many peopleare malnourished prior to admission to hospital • People in hospital are at risk of becoming malnourished or further malnourished • Prevalence of malnutrition in hospital has been quoted as 40% (McWhirter & Pennington, 1994) • Up to 43% of patients in ICU are malnourished (Giner et al, 1996) 12Prof. Dr. RS Mehta, BPKIHS
  • 13.
    Consequences of malnutrition •Weight loss • Weakness and fatigue • Impaired ventilatory drive  DEATH • Depression / apathy • Poor wound healing • Impaired immune function Webb (1999), Garrad (1996) 13Prof. Dr. RS Mehta, BPKIHS
  • 14.
    Why feed thecritically ill? • Provide nutritional substrates to meet protein and energy requirements • Help protect vital organs and reduce break down of skeletal muscle • To provide nutrients needed for repair and healing of wounds and injuries • To maintain gut barrier function • To modulate stress response and improve outcome 14Prof. Dr. RS Mehta, BPKIHS
  • 15.
    Prof. Dr. RSMehta, BPKIHS 15 Nutritional Assessment • History – 10% weight loss or more suggests protein malnutrition • Exam – Weight/Ideal body weight (<85% predicted), temporal muscle wasting, anthropometrics • Nutritional markers -albumin -haemoglobin -urea -creatinine - glucose in blood
  • 16.
    Prof. Dr. RSMehta, BPKIHS 16 Body Mass Index (BMI) and Nutritional Status BMI Nutritional Status >30 kg/m2 Obese >25–30 kg/m2 Overweight 20–25 kg/m2 Normal <18.5 kg/m2 Moderate malnutrition <16 kg/m2 Severe malnutrition <13 kg/m2 Lethal in males <11 kg/m2 Lethal in females
  • 17.
    Checklist for malnutrition •Illness • Eating poorly • Tooth loss or mouth pain • Economic hardship • Reduced social contact • Multiple medicine • Involuntary weight loss or gain • Assistance in self care • Elders above 80 yrs . Prof. Dr. RS Mehta, BPKIHS 17
  • 18.
    Basal energy expenditure Thebasal energy expenditure is easily calculated from the Harris-Benedict equation is : For men: • 66+(13.7 18ₓ w)+(5ₓH)-(6.8ₓA) For women: • 65.5+(9.6ₓw)+(1.8ₓH)-(4.7ₓ A) W=weight in kg, H=height in centimeters, A=age in years. 18Prof. Dr. RS Mehta, BPKIHS
  • 19.
    Prof. Dr. RSMehta, BPKIHS Nutritional Therapy • Healthy adult – approx 25 kcal/kg/day, 1g protein/kg/day • Pretty sick to moderately sick – 30 kcal/kg/day, 1.5g protein/kg/day • Very sick – 35 kcal/kg/day, 2g protein/kg/day • Very Very sick - 40 kcal/kg/day, 2.5g protein/kg/day
  • 20.
    Hospital diet The treatmentof a disease or disorder with a special diet. Dietary prescriptions include: 1.clear liquid 2. full liquid diet 3.soft diet Special Diets (low-residue, high-fiber, liberal bland, fat-controlled, sodium-restricted). Hospital diet 20Prof. Dr. RS Mehta, BPKIHS
  • 21.
    • This dietshould be completely free of any solids, E.g. tea or coffee without cream or milk, clear soup, filtered fruit juices etc. • Nutritionally inadequate, used for a very short period of time . • Full liquid diet should be given for all acute conditions before diagnosis. Liquid diet-clear 21Prof. Dr. RS Mehta, BPKIHS
  • 22.
    Full liquid diet •It consists of Fruit juices Soup Milk Curd Ice-cream Lassi Custard Prof. Dr. RS Mehta, BPKIHS 22
  • 23.
    Contd……. • Liquid dietis suitable for conditions: Head Injuries, Gastroctomy Cases, Paralytic Syndrome and other Conditions where the patients are unable to swallow., First 24-48 hours in Caardiovascular Disorders and Post Operative Cases , Severe Burns. 23Prof. Dr. RS Mehta, BPKIHS
  • 24.
    Items for NGtube feeding • Liquid diet • Skimmed milk • Skimmed milk powder. • ICU diet. • Strained fruit juice and vegetable soup. • Egg powder. • Sugar or molasses. 24Prof. Dr. RS Mehta, BPKIHS
  • 25.
    25 N G Tubefeeding esp. 1. Calories (sick): 30 cal/kg/24 hrs eg. Pt. wt. 30 kg = 30x30 =900 K cal/24 hr Idealy 1 cal. = 1 cc, hence = 900 cc 2. For severe sick( eg. Burn): 40 cal/kg/24 hr In cal = fat 20-30% & CHO = 60-80 % Extra Protein+ Vitamin + Minerals etc Water: 2 ml/kg/hr (IV or Oral) Prof. Dr. RS Mehta, BPKIHS
  • 26.
    Churn diet/ blenderizeddiet in BPKIHS • Rice, dal and vegetables blended together • Fruits, curd and fish can also be added • Protein and other supplements provided separately 26
  • 27.
    Protocol in BPKIHSfor enteral feeding • Frequent mouth care. • The nasal tape is changed as necessary • Throat lozenges, an ice collar, chewing gum, or sucking on hard candies (if permitted) • Head end elevation- 45 degrees for 1 hour before, during and 1 hour after gastric feeding. • Strict hand washing before handling the feeding formula and equipment • Do not Use excessive force when administering anything 27
  • 28.
    • Do notUse cold water • Residual monitored every 4 hours. • Maintain adequate hydration by providing Water (at least 2 L/day) every 4 to 6 hours and after feedings and observe for signs of dehydration • Proper storage of the formula- refrigerate diluted or reconstitued formula and formula that contains additives 28
  • 29.
    To ensure patencyand to decrease bacterial growth, 20 to 30 mL of water is administered Before and after each dose of medication and each tube feeding After checking for gastric residuals and gastric pH Every 4 to 6 hours with continuous feedings If the tube feeding is discontinued for any reason 29
  • 30.
    In case oftube occlusion • Inject warm water and agitate with syringe. • If ineffective (dissolve 1 tablet Violase with 1 tablet sodium carbonate in 5 ml. Inject and clamp for 5 minutes). 30
  • 31.
    Guidelines for theadministration for medications via enteral feeding tube • If possible administer the medication by mouth • Use a liquid form of the medication if available • If the medication can be crushed, crush it to a fine powder and dissolve it in 30 ml of water • Do not crush enteric coated or time released tablet or capsule • Flush the tube with 30 ml of water before and after giving each medication • Do not mix multiple medication or give them together • Do not deliver a medication into the small intestine if it must be absorbed in the stomach such as sucralfate or antacids • Hold feeding 1 or 2 hours before and after giving a medication that might have drug nutrient interaction such as phenytoin 31
  • 32.
    Maintaining normal bowelelimination Common problems • Diarrhea (three or more times in 24 hours), commonly due to feeding formula and medication like acetaminophen, ferrous sulphate, metoclopramide, KCl, Theophylline • The dumping syndrome due to Zinc deficiency, rapid distention of the jejunum when hypertonic solutions are administered quickly (over 10 to 20 minutes) • Malnutrition—due to decreased absorption Management • Adding 15 mg of zinc to the tube feeding every 24 hours 32
  • 33.
    Indications for parenteralnutrition • The main indication for parenteral nutrition is when the gut is not functional and who is requiring complete bowel rest. Examples of inadequate gut function might include: • Bowel obstruction or suspected gut ischemia • Some types/locations of gastrointestinal fistula • Short bowel syndrome due to surgery • Persistent severe diarrhea or significant malabsorption • Persistent signs of significant gut dysmotility (a distended and/or painful abdomen, persistent large gastric aspirates, no bowel output) • Some stages of ulcerative colitis 33
  • 34.
  • 35.
    35 Parenteral Nutrition • 3liters of fluid necessary to give enough calories via TPN due to limitations on dextrose content due to phlebitis risk. • Dextrose administration should not exceed 3.5mg/kg/min to avoid metabolic complications. • Fats – Septic patients have decreased ability to utilize dextrose, but use fats well – Also prevents essential fatty acid deficiency Prof. Dr. RS Mehta, BPKIHS
  • 36.
    Indications of TPN: •Intestinal obstruction, or surgery. • Gastrointestinal fistula. • When the bowel needs to rest : Crohn’s disease, pancreatitis, ulcerative colitis. • Prolonged diarrhoea in children. • Severe burns, multiple fractures or severely malnourished individuals. 36Prof. Dr. RS Mehta, BPKIHS
  • 37.
    Content of TPN •For an adult a standard TPN solution Content: amino acids, fat emulsions, dextrose, electrolytes, trace elements, vitamins and additives. • Calorie: 60% CHO, 20% protein and fat each. 37Prof. Dr. RS Mehta, BPKIHS
  • 38.
    Recommended amount of electrolytesper day • Sodium 40-100 mmol or 1-2 mmol/kg • Potassium 60-150 mmol or 1-2 mmol/kg • Calcium 2.5-5 mmol • Magnesium 4-12 mmol • Phosphorus 10-30 mmol • Chloride As needed to maintain acid-base balance with acetate 38
  • 39.
    Choice of nutritionregimen • Parenteral nutrition infusions can be: –Continuous (running 24 hours a day), cyclic (running for a period of between 8 and 18 hours each day) Or –Intermittent (on some days only). 39
  • 40.
    TPN 40Prof. Dr. RSMehta, BPKIHS
  • 41.
    Parenteral nutrition infusionrate • Typical infusion rates vary between 40- 150mL/h, but cyclic infusions may be delivered at rates as high as 300mL/h. 41
  • 42.
    Stopping parenteral nutrition •Close monitoring with hourly blood glucose testing, for several hours • Abruptly stopping parenteral nutrition cause a rebound hypoglycemia in some patients due to ongoing action of insulin • For patients with normal blood glucose levels who have not been receiving insulin, the infusion can usually just be stopped. • Those receiving insulin,-brief tapering regimen: ensure that insulin infusions are ceased, that other insulin dosage is reviewed, and then decrease the parenteral nutrition infusion rate by half for an hour. • Alternatively the parenteral nutrition can be replaced with a 10% dextrose infusion at the same rate for an hour, before stopping completely. 42
  • 43.
    Role of nursein care of patients with TPN • Care of the vascular access site • Physical management of the parenteral nutrition infusion and the related equipment • Training for the home parenteral nutrition • Assistance for insertion of vascular access device 43
  • 44.
    Prof. Dr. RSMehta, BPKIHS Complication • Mechanical: occlusion, catheter removal, improper rate, thromboses, pneumothorax. • Infection: catheter related • Metabolic: re-feeding syndrome, hyperglycemia, fluid & electrolyte disturbance • Organic system: hepatobiliary complication, respiratory, cardiovascular, renal 44
  • 45.
    45Prof. Dr. RSMehta, BPKIHS
  • 46.
    Separate container 46 Single, Doubleand Triple Bag: Carbohydrate, Lipid and Amino acid
  • 47.
  • 48.
  • 49.
    Available in solution •Trade name: Addamel N • Generic name: trace elements with selenium and iodide • Trade name: Intralipid • Generic name: fat emulsion • Trade name: Aminosyn Generic name: parenteral nutrition solution 49
  • 50.
    Enteral vs. ParenteralNutrition Enteral Parenteral Advantages -Physiological -Simpler -Cheaper -No CVL required -Less monitoring -Less complication Advantages -Independent of GIT functions Disadvantages -Dependent on GIT functions -Diarrhea -Feed intolerance -NG tube – malposition, sinusitis -Pulmonary aspiration Disadvantages -Non physiological -Requires venous access -Higher risk of systemic infection -Expensive -More complication 50Prof. Dr. RS Mehta, BPKIHS
  • 51.
    Enteral Parenteral Complications 1. Mechanical -GEReflux -NGcomplication – oesophageal perforation, throat injuries, tracheal placement, blockage, rupture oesophageal varices 2. Infection -Sinusitis, otitis -Pulmonary aspiration -Feed contamination 3. GIT – nausea, vomit, diarrhea 4. Metabolic -dehydration, hyperglycaemia -electrolyte abnormality -acid base imbalance Complications 1. CVL related complication 2. Fluid overload 3. Hyperosmolar dehydration syndrome – hyperglycaemia, osmotic diuresis 4. Electrolytes imbalance 5. Metabolic acidosis 6. Hyperammonaemia 7. Deficiency Syndromes 8. Rebound hypoglycaemia – if TPN stopped suddenly due to high level endogenous insulin 9. Overfeeding syndrome. 51Prof. Dr. RS Mehta, BPKIHS
  • 52.
    52 Nutrition for criticallyill patients Daily energy expenditure: 1. Basal energy expenditure ( BEE ): amount of energy required for basal metabolism. (during resting & fasting) 2. Resting energy expenditure ( REE): When person is resting but not fasting. BEE: 25 X weight in Kg. REE: 1.2 x BEE Prof. Dr. RS Mehta, BPKIHS
  • 53.
    53 Fever: energy required= BEE X 1.1 For each oF rise, energy = BEE x 1.1 x 2 According to level of stress: 1. Mild: E. required: 1.2 x BEE 2. Moderate: E. required: 1.4 x BEE 3. Severe : E. required: 1.6 x BEE Prof. Dr. RS Mehta, BPKIHS
  • 54.
    54 • 70 %Energy is given by CHO • 30 % Energy is given by Lipid • Protein is not given for energy but only for tissue development. • Protein: 0.8-1 gm/kg body wt. (normal) • If pt. is hyper-catabolism ( Fever, hyper- thyrodism), then protein = 1.2 to 1.6 gm/kg • Multivitamin in 5% Dextrose, if pt. on IVF and NPO Prof. Dr. RS Mehta, BPKIHS
  • 55.
    SUMMARY • Diet isthe sum of food consumed by a person or other organism. healthy person's diet = balanced diet. • A healthy person's diet includes multitude of vitamins, minerals and other beneficial nutrients. Different medical diseases constitutes different meal patterns. 55Prof. Dr. RS Mehta, BPKIHS
  • 56.
    Conclusion • Do notforget about feeding • Keep an eye on whether nutritional targets are being met • Speak to the surgeons and dietician • Do not be reluctant to start PN in a supplemental capacity • Avoid hyperglycaemia • Nutrition is often neglected 56Prof. Dr. RS Mehta, BPKIHS
  • 57.
    57Prof. Dr. RSMehta, BPKIHS
  • 58.
    58Prof. Dr. RSMehta, BPKIHS