More Effective National Food
and Nutrition Policy:
Balancing the Role of Research,
Nutrition Science, and Public Health
© 2015 Institute of Food Technologists
Presenters:
Joanne Slavin, PhD, RD, University of Minnesota
The Widespread Effects of Food and Nutrition Policy
on Public Health
► Segment takes a look back at the history of the Dietary Guidelines
for Americans and how they have progressed over the past 35
years
Today we will hear from…
Moderator: Elizabeth Crawford
Senior Correspondent, Food Navigator-USA
2
© 2015 Institute of Food Technologists
Connie M. Weaver, PhD, Purdue University
The Importance and Deficiencies of Consistent,
Systematic Evaluation Processes in Policymaking
► Examination of the evaluation processes used by policymakers and
provided examples of how differences among these processes can
lead to varying results
Roger Clemens, DrPH, University of Southern California
The Role of Scientific Research in Food and Nutrition
Policy
► An exploration of the different types of research used to set nutrition
policy and how varying strengths of this research often lead
scientists to presume outcomes that may not hold true after
stronger research emerges
3
Joanne Slavin, PhD, RD
Professor
Department of Food Science and Nutrition
University of Minnesota
jslavin@umn.edu
The Widespread Effects of Food and
Nutrition Policy on Public Health
Disclosures for Joanne Slavin
AFFILIATION/FINANCIAL
INTERESTS
(past 12 months)
CORPORATE
ORGANIZATION
Grants/Research Support: American Pulse
Association
Scientific Advisory
Board/Consultant:
Tate and Lyle, Atkins,
Kelloggs
Speakers Bureau:
Stock Shareholder:
Other
© 2015 Institute of Food Technologists5
From Science to Me
The Science Policy Me
© 2015 Institute of Food Technologists6
There is no perfect diet!
► Humans are omnivores, like pigs, and are adaptable to
a wide range of foods
► Humans have survived and prospered on all kinds of
diets, mostly reflecting access to food supply
• Traditional Arctic diet: 80% of kcals from fat
• Traditional African diet: 80% of kcals from carbohydrate
► Because of concerns with fat and cardiovascular
disease, U.S. diet has moved from higher fat (42% of
kcal in 1972) to lower fat (32% of kcal in 2000) – but
more calories
© 2015 Institute of Food Technologists7
Dietary Guidance—A Historical Perspective
1894 - Dr. W.O. Atwater specified amount of protein and total calories in a good
diet, but left unspecified the division of calories between fats and
carbohydrates
1902 - “evils of overeating may not be felt at once, but sooner or later they are
sure to appear – perhaps in general debility, perhaps in actual disease”
1902 - “ordinary food materials…make a fitting diet, and the main question is to
use them in the kinds and proportions fitted to the actual needs of the body”
Recommended variety, proportionality and moderation, measuring calories,
and an affordable diet focused on nutrient-rich foods, less fat, sugar and
starch.
© 2015 Institute of Food Technologists8
Nutritional science – nutrients to prevent
deficiency diseases
1941:
 National Academy of Sciences began issuing “Recommended
Dietary Allowances” – quantity of nutrients a person needed to
consume daily to ensure basic good health, proper growth and
reproductive success, and to prevent nutrient deficiency diseases.
 Nutritional deficiency diseases have been virtually eliminated in the
U.S., thanks to enrichment of refined grains and other fortification
strategies.
© 2015 Institute of Food Technologists9
Nutrient Adequacy
 Meet nutrient needs without exceeding calorie needs
 Dietary Reference Intakes (DRIs)
• Acceptable Macronutrient Distribution Ranges (AMDR)
- Protein: 10 - 35% of kcal
- Carbohydrates: 45 - 65% of kcal
- Fat: 20 - 35% of kcal
• Recommended Dietary Allowance (RDA)
• Adequate Intake (AI)
• Tolerable Upper Level Intake (UL)
© 2015 Institute of Food Technologists10
Senate Select Committee on Nutrition and Human
Needs – Dietary Goals the United States (1977)
► Increase carbohydrates to 55%–60% of energy
► Reduce fat to 30% of energy
► SF, MF, PUFAs – 10%/10%/10%
► Reduce cholesterol to 300 mg/day
► Reduce sugar consumption by 40%
► Reduce salt consumption to 3 g/day – 1200 mg
sodium
© 2015 Institute of Food Technologists11
Toward Healthful Diets, FNB, 1980
“The Board expresses its concern over excessive hopes
and fears in many current attitudes toward food and
nutrition. Sound nutrition is not a panacea. Good food that
provides appropriate proportions of nutrients should not be
regarded as a poison, a medicine, or a talisman. It should
be eaten and enjoyed.”
© 2015 Institute of Food Technologists12
Dietary Guidelines for Americans 1980 - 2010
1980
1985
1990
1995
2000
2005
2010
© 2015 Institute of Food Technologists13
DGAC
Advisory Report
submitted to the
Secretaries of
USDA & HHS
USDA & HHS
write the
Policy
Document
DGAC is
chartered DG’s
implemented
through Federal
programs
DGAC
Charter
DGAC
Public Meetings:
Review of the
Science
Evidence-based Methodology Used to Review the Science
Public comments encouraged/collected
Dietary Guidelines
for Americans,
2010
(TBD)
U.S. Department of Agriculture
U.S. Department of Health and
Human Services
www.dietaryguidelines.gov
The
New
“Pyramid”
Development of Dietary Guidelines Policy
© 2015 Institute of Food Technologists14
Total Diet 2010 DGAC Conclusions:
Not Evidence-Based
Key Topics:
 Overweight/obese nation
 Develop healthy dietary patterns in childhood and
adolescence
 Maintain energy intake within calorie needs
 Maximize nutrient density by emphasizing whole grains,
vegetables, fruits, milk/milk products, and oils
 Reduce solid fats and added sugars and sodium
 Flexible eating patterns
© 2015 Institute of Food Technologists15
Chapter 3
Foods and Food Components to Reduce
© 2015 Institute of Food Technologists16
Chapter 4
Foods and Nutrients to Increase
© 2015 Institute of Food Technologists17
Comparison of Consumption
to Recommendations
© 2015 Institute of Food Technologists18
DGAC 2015
► “Settled science” – may not see much change on
nutrient levels
► Movement to whole foods and away from nutrients
► Topics such as sustainability, gluten, vegan diets,
and food processing have been discussed and may
be included in 2015 DGA
© 2015 Institute of Food Technologists19
2015 DGAC – Dietary patterns, foods and
nutrition, and health outcomes
► The US population should consume dietary
patterns that are:
• Rich in vegetables, fruits, whole grains, fish/seafood,
legumes, and nuts
• Moderate in dairy products (e.g. low and non-fat
dairy) and alcohol and
• Lower in red and processed meat and
• Low in sugar-sweetened foods and beverages and
refined grains
© 2015 Institute of Food Technologists20
2015 DGAC – Food and nutrient intakes, and
health: Current status and trends
► The US population has low intakes of certain key nutrients – vitamin
D, potassium, fiber, calcium, and for females also iron. These low
intakes are a public health concern because inadequate intakes are
linked to health problems
► The US population over consumes sodium and saturated fat.
Excess intakes of these nutrients are also linked to health problems
► Many of the food groups that are good sources of under consumed
nutrients are consumed in low amounts by the US population
► Many of the food groups and food categories that have high levels
of sodium, saturated fat, and added sugars are consumed in high
amounts
© 2015 Institute of Food Technologists21
1943: Basic Seven
Margaret Mead: “People
don’t eat nutrition –
they eat food”
Basic 7 did not specify
the number of servings
of each food group
needed daily
© 2015 Institute of Food Technologists22
1940s1950s-1960s
1970s
1992
Food for
Young
Children
1916
2005
Food advice: Evolution of USDA’s Food
Guidance – Moderation and Variety
© 2015 Institute of Food Technologists23
MyPlate.gov (6/2/11)
© 2015 Institute of Food Technologists24
Key Takeaways
► Evidence-based reviews are limited in our ability to define
“healthy foods”
► Recommendations for less added sugar and solid fats are
based on empty calories, not health outcomes – USDA
modeling
► Since nutrition research does not support that vegetarian diets
are healthier than animal based diets, there is a movement to
“sustainability” as the reason to support plant-based diets
► Solving important nutrition problems will require partnerships
based on trust among academics, the government, commodity
groups, and food companies
© 2015 Institute of Food Technologists25
Connie M. Weaver, Ph.D.
Purdue University
West Lafayette, IN
weavercm@purdue.edu
The Importance and Deficiencies of
Consistent, Systematic Evaluation
Processes in Policymaking
Disclosures for Connie Weaver
AFFILIATION/FINANCIAL
INTERESTS
(past 12 months)
CORPORATE
ORGANIZATION
Grants/Research Support: NIH, DRI, Nestle,
Tate & Lyle
Scientific Advisory
Board/Consultant:
NOF, ILSI, Showalter,
Pharmavite
Speakers Bureau:
Stock Shareholder:
Other
© 2015 Institute of Food Technologists27
Outline
► Evidence-based approach
► Difficulties encountered with evidence-based
approach in nutrition
© 2015 Institute of Food Technologists28
The Philosophy Behind
an Evidence-based System
► Rules are set “up front” then followed,
rather than having a preconceived idea
and then finding the papers to support
the idea.
► If one follows the rules, any trained
scientist should come to the same
conclusion.
© 2015 Institute of Food Technologists29
Hierarchy of
Evidence
RCT
Double Blinded
RCT
Cohort Study
Case Control
Case Series
Case Report
Expert Opinion
Weaker
Evidence
Stronger
Evidence
Evidence-based Medicine Hierarchy
Consistency ends here!
© 2015 Institute of Food Technologists30
No Consistent Literature Retrieval
or Grading Systems
► NIH-AHRQ
► FDA-own system for health claims
► Various other approaches
Slavin Nutr J 14:15, 2015
© 2015 Institute of Food Technologists31
Nutrition Evidence Library (NEL) Process
Define Research Recommendations
Dietary Guidelines Advisory Committee
Since 2010:
Summarize
and Synthesize
the Evidence
•Assess quality
of individual
studies
•Assess
applicability
•Summarize
and synthesize
evidence
Develop
and Grade
Conclusion
Statements
Formulate
Systematic
Review
Questions
•Exploratory
searches
•Public
comment
•Dialogue with
experts
•Analytical
Framework
•PICO
Literature
Search and
Sort
•Identify study
eligibility criteria
•Determine search
strategy
•Search for
relevant studies
•List included
studies
•List excluded
studies and
rationale
Extract
Evidence
From
Studies
Create
evidence
worksheets
© 2015 Institute of Food Technologists32
Grade Strength of Evidence
► Quality
• Scientific rigor and validity
• Consider study design and execution
► Quantity
• Number of studies/sample sizes
► Consistency of findings across studies
► Impact
• Importance of studied outcomes/magnitude of effect
• Magnitude of effect
► Generalizability
Grades: 1.STRONG; 2. MODERATE; 3. LIMITED
© 2015 Institute of Food Technologists33
 Search term + bone + child + adolescence
 Excluded: reviews, animal studies, non-English
 Subcommittees reviewed abstracts and
excluded
• If not RCT or observational study
• No bone outcomes
• Interventions <6 mo.
• Drug trials of disease states
ASN Scientific Statements
Example of Development of Peak Bone Mass
PubMed search of scientific literature Jan 2000-Dec 2014
© 2015 Institute of Food Technologists34
Level of Evidence Description
A: Strong One large, well-conducted, generalizable, RCT
OR
Multiple RCTs or trials with few limitations
B: Moderate Multiple prospective cohort studies.
OR
Meta-analysis of prospective cohort studies.
C: Limited Multiple prospective cohort studies from diverse populations that have
limitations.
OR
One well-designed prospective study.
OR
Multiple cross-sectional or case-controlled studies with few limitations.
OR
Meta-analysis with design limitations.
D: Inadequate Methodologic flaws
OR
Insufficient data.
Evidence Grade
© 2015 Institute of Food Technologists
35
Differences in process for
evaluating scientific evidence can
lead to different conclusions
Example: Choosing different end
points concern over salt
© 2015 Institute of Food Technologists36
2010 Dietary Guidelines Advisory
Committee Conclusions
► A strong body of evidence has documented that
in adults, as sodium intake decreases, so does
blood pressure.
► A moderate body of evidence has documented
that as sodium intake decreases, so does blood
pressure in children, birth to 18 years of age.
► The reduction from 2,300 mg to 1,500 mg per
day should occur gradually over time. [about
750 mg/1000kcal]
© 2015 Institute of Food Technologists37
IOM Committee on Consequences
of Sodium Reduction in Populations
– Released May 14, 2013
 Calls for national action to reduce sodium
content of foods - average intake 3400 mg
Na/d
 Evidence weak to strive for less than 2300 mg
Na/d – need more studies between 1500 and
2300 mg/d
Focused on disease outcomes beyond blood
pressure
© 2015 Institute of Food Technologists38
2015 DGAC
Sodium Recommendations
<2300 mg/day
© 2015 Institute of Food Technologists39
There is NO guarantee of
consensus conclusions even if
you use same process and end
points
© 2015 Institute of Food Technologists40
© 2015 Institute of Food Technologists41
What is the Relationship Between Calcium
and Vitamin D and Hip Fracture?
Women’s Health Initiative RCT of CaD
(n=68,719 postmenopausal women)
Prentice et al., Osteopor Int 24:567, 2013
• All subjects including those
taking own supplements
• >5 Year CaD Intervention-related Health
Outcomes in Subjects Adherent & Not
Taking Baseline Supplements
No relationship
Large benefit
© 2015 Institute of Food Technologists42
Difficulties of Applying
Evidence-Based Medicine
Approach to Nutrition
© 2015 Institute of Food Technologists43
Ranking of Study Type
► The RCT is given greatest weight because
it is the only design that permits strong causal
inference
► But for nutrition, that often means sacrificing
control of the independent variable (nutrient
diet) in favor of the dependent variable (health
outcome)
© 2015 Institute of Food Technologists44
RCT Trials are Designed for a Compound
That:
 Works quickly
 Usually pinpointed to 1
pathway or 1
mechanism of action
 That is: a drug
© 2015 Institute of Food Technologists45
Features of RCTs for Drugs
► Tested in or applied to sick people
► Test agent is contrasted with its absence
compared to a nutrient where there can be no
nutrient-free state
► Sharply defined primary outcome measure
► Effect size usually large compared to a nutrient
► Response characteristic is usually monotonic
across plausible intakes
© 2015 Institute of Food Technologists46
Contrasts
► Drug – drug-added state is contrasted
with drug-free state
► Nutrient – “high” intake is contrasted with
“low” intake
© 2015 Institute of Food Technologists47
Effect Size
► Drug- usually large
► Nutrient – usually small, but
• public health impact may nevertheless be large
• aggregate effect across multiple
• systems is itself often large
© 2015 Institute of Food Technologists48
Consequence
► When changes are small, testing for isolated
nutrient effects requires large, expensive,
lengthy studies if effects in isolated systems
are to be found statistically significant.
© 2015 Institute of Food Technologists49
INTAKE
EFFECT
Study Design & the Threshold
the control group
must be deficient
© 2015 Institute of Food Technologists50
The Ethical Problem
► Placing the control group on a clearly
inadequate intake
© 2015 Institute of Food Technologists51
Underreporting error for energy intake in overweight boys and girls was 35+18%
EIas%ofTEE
Girls Boys
Reported EI
Weight adjusted
MEI
TEE by DLW
Singh, 89(6):1744-1750, 2009
Concern with Diet Assessment
for Observational Studies
© 2015 Institute of Food Technologists52
Controlled Feeding Studies
► Historically ranked highest for evidence
for nutrients/diet
► Minimizes confounders and allows study
of range of known intakes
© 2015 Institute of Food Technologists53
Animal Studies
► Can have controlled diet and sufficiently long
duration for cancer outcome measures.
• But relevance to humans?
► Invasive procedures
► Mechanistic
© 2015 Institute of Food Technologists54
Future Needs
► Good biomarkers are the most needed tool in
research related to diet and health. Current
biomarkers for intake and health outcome
measures range from weak to moderately
good. Even the better ones need validation.
© 2015 Institute of Food Technologists55
Kinds of Evidence
Basic
Research
Translational
Research
Efficacy
Studies
Effectiveness
Research
How does
it work?
Can it be
studied in
people?
Specific
effects?
How good
is the
translation?
© 2015 Institute of Food Technologists56
Best recommendations
use the totality of
evidence with liberal
doses of critical thinking
and LOGIC!
© 2015 Institute of Food Technologists57
The Role of Scientific Research in
Food and Nutrition PolicyRoger Clemens, DrPH, CFS, CNS, FACN, FIFT, FIAFST
Adjunct Professor, Pharmacology and Pharmaceutical Sciences
USC School of Pharmacy, Los Angeles
clemens@usc.edu
The Role of Scientific Research in
Food and Nutrition Policy
Disclosures for Roger Clemens
AFFILIATION/FINANCIAL
INTERESTS
(past 12 months)
CORPORATE ORGANIZATION
Grants/Research Support: None
Scientific Advisory
Board/Consultant:
Spherix Consulting, Mushroom Council,
Almond Board of California, California
Walnut Commission, Abbott Nutrition,
FMC, Numerous Law Firms
Speakers Bureau: IFT, ASN
Stock Shareholder: None
Other Daedalus Humanitarian/Foundation
© 2015 Institute of Food Technologists59
► Improve health through food
► Provide food that is safe,
nutritious, affordable and
accessible
► Implement consistent policy
► Establish dietary clear
guidelines
Dietary Guidelines
and Global Imperatives
• Need health literacy
• Need developmental
approach to dietary
guidelines
• Need to recognize
nutrition needs
throughout life cycle
• Need applied research
based on food
• Need public/private
partnerships
• Need to shift cultures of
health
© 2015 Institute of Food Technologists60
► Over 35 years, increased prevalence of NCD
► Medical expenses associated with obesity: $200-300B
► > $100B spent on nutrition assistance programs
~ 70% of SNAP support families with children
► ~24MM people in low income
► ~20% children are food insecure
► Food and inactivity leading contributors of
death in the USA
J. Michael McGinnis, M.D., M.A., M.P.P., IOM Senior Scholar, May 21, 2015
► Agriculture is responsible for much of the progress humanity has
made against hunger. The only way that the world can keep up
with food production is by the improvement of science and
technology.
Norman Borlaug, Nobel Laureate, 1970
Health Today
© 2015 Institute of Food Technologists61
► Examine the Dietary Guidelines for Americans, 2010 and determine topics for
which new scientific evidence is likely to be available that may inform
revisions to the current guidance or suggest new guidance.
► Place its primary focus on the systematic review and analysis of the
evidence published since the last DGAC deliberations.
► Place its primary emphasis on the development of food-based
recommendations that are of public health importance for Americans ages 2
years and older.
► Prepare and submit to the Secretary of Health and Human Services and the
Secretary of Agriculture a report of technical recommendations, with
rationales, to inform the development of the 2015 Dietary Guidelines for
Americans. DGAC responsibilities include providing authorship for this report;
however, responsibilities do not include translating the recommendations into
policy or into communication and outreach documents or programs.
Charge to the 2015 DGAC
http://www.health.gov/dietaryguidelines/2015-binder/2015/chargeCommittee.aspx June 2013
© 2015 Institute of Food Technologists62
Assessing the Evidence
► Observational claims are not necessarily validated via
clinical trials.
► Clinical studies among small populations do not necessarily
translate to total population (think public policy)
► Common words like “association,” “related,” and “relative
risk” imply strength, yet upon review the work is generally
quite weak
► “Definitive solution will not come from another million
observational papers or a few small randomized trials”
Ioannidis JPA BMJ 2013;347: doi: 10.1136/bmj.f6698
© 2015 Institute of Food Technologists63
► Systematic reviews and meta-analyses
• Different inclusion/exclusion criteria impact
results
• Different statistical approaches and choices of
covariates impact results
• Dietary exposures are not accurate
• Associations  Causes
• Reflect the perspectives of others
Research Bias
Nicklas et al., J Nutr 2014; doi: 10.3945/jn.114.194068
© 2015 Institute of Food Technologists64
It is…important to not be distracted by questions
that we have not been asked to address.
What was Asked?
What’s missing in many [meta analysis and
systematic review] studies published since 2010
DGAC?
 Undefined and inconsistent
outcomes
 Intention to treat analysis
 Complete case analysis
 Unexplained discontinuances
 Imputed baseline data extended
beyond current analysis
 Multiple imputations in analyses
© 2015 Institute of Food Technologists65
Kaiser et al. Obes Rev 2013; doi: 10.1111/obr.12048.
Ecological Relation of Water Intake with
Prevalence of Overweight/Obesity: 1961-2000
Rise in obesity rates (round markers) and bottled water consumption (square markers). USA
© 2015 Institute of Food Technologists66
Consumer Confusion
Confidence
Confusion
IFIC 2012:
• Three out of four consumers feel that changes in nutritional
guidance makes it hard to know what to believe
• Half believe it is easier to do their own taxes than to figure out
how to eat healthfully
International Food Information Council Foundation 2012 Food & Health Survey . Consumer Attitudes
Toward Food Safety, Nutrition & Health
http://www.foodinsight.org/Content/3840/2012%20IFIC%20Food%20and%20Health%20Survey%20Repo
rt%20of%20Findings%20(for%20website).pdf
© 2015 Institute of Food Technologists67
Do Scripted Diets Work for Policy?
What about Low-fat Diets?
2015 DGAC Meeting 5, September 16, 2014
© 2015 Institute of Food Technologists68
Comments
► Chowdhury: “My take on this would be that it’s not saturated fat that
we should worry about” in our diets.
► Hu: The findings should not be taken as “a green light” to eat more
steak, butter and other foods rich in saturated fat. … looking at
individual fats and other nutrient groups in isolation could be
misleading, because when people cut down on fats they tend to eat
more bread, cold cereal and other refined carbohydrates that can
also be bad for cardiovascular health.
► Hu: “The single macronutrient approach is outdated. I think
future dietary guidelines will put more and more emphasis on real
food rather than giving an absolute upper limit or cutoff point for
certain macronutrients.”
► Hu: People should try to eat foods that are typical of the
Mediterranean diet, like nuts, fish, avocado, high-fiber grains and
olive oil.
Rajiv Chowdhury,
PhD
Cardiovascular
Epidemiologist
University of Cambridge
Frank Hu, MD, PhD
Professor of Nutrition and
Epidemiology
Harvard University
http://acsh.org/2014/03/huge-new-re-evaluation-saturated-fat-heart-risk-finds-link/
March 18, 2014
© 2015 Institute of Food Technologists69
► Cholesterol is not a nutrient of concern for
overconsumption.
► Saturated fat is still a nutrient of concern for
overconsumption, particularly for those
older than the age of 50 years.
Dietary Cholesterol and Saturated Fat
© 2015 Institute of Food Technologists70
► There is insufficient evidence that an exchange of sugar
for non-sugar carbohydrates results in lower body
weights (a calorie = a calorie)
► Observational (cross-sectional) studies suggest a
possible relationship between consumption of sugar-
sweetened beverages (SSB) and body weight; no
supporting RCTs
► Insufficient evidence to support a difference between
liquid and solid sugar intake and body weight control
Added Sugars and Body Weight
Key reference: van Baak & Astrup. Obes Rev 2009; 10 Suppl 1:9-23
© 2015 Institute of Food Technologists71
Agency Statement
2010 DGAC RCTs report that added sugars are not different from
other calories in increasing energy intake or body
weight. Systematic reviews in this area are also
inconsistent.
EFSA 2012 …a cause and effect relationship has not been
established between total sugar intake and body weight
gain
WHO 2015
(Te Morenga et al, 2014)
‘Trials in children, which involved recommendations to
reduce intake of sugar sweetened foods and beverages,
had low participant compliance to dietary advice; these
trials showed no overall change in body weight.’
German Nutrition Society
2012
In general, meta-analyses are inconsistent. The most
recent meta-analysis concludes that the risk-increasing
effect is limited to individuals with initially already
increased BMI or existing overweight, respectively
Sugar in Context
© 2015 Institute of Food Technologists72
Food, Nutrition & Health
• Secondary Education
Challenge
• Community Food Projects
• Higher Education Challenge
• 1890 Capacity
• Food Safety, AFRI
• Climate Variability and
Change, AFRI
• Food Security, AFRI
• Foundational Program, AFRI
• Alaska Native & Native
Hawaiian Institutions
• Federally Recognized Tribes
Extension Program
• Hispanic-Serving Institutions
Education
• Multicultural Scholars
• National Needs Graduate
Fellowships
• New Technologies for Ag
Extension
• Rural and Community
Development, SBIR
• Tribal Colleges Education
Equity
• Tribal Colleges Extension
• Tribal Colleges Research
© 2015 Institute of Food Technologists73
► FDA Investment
• Further scientific knowledge about
potential
food hazards
• Expand on best safety practices
• Better understand how consumers access,
prepare, and use the foods they serve and
eat
► CFSAN Research Strategic Plan
• Globalization of the food supply chain
• Changing industry processes
• Consumer preferences for fresh and
minimally processed foods
Science & Research (Food)
Where’s Food
Science and
Nutrition?
Where’s
Agriculture?
© 2015 Institute of Food Technologists74
►Criteria for NNMAC representation (Title II)
– At least two representatives selected solely on basis of
established record of distinguished service and eminence in
many disciplines and fields (>20)
• Various geographical areas
• Private sector
• Academia
• Scientific and professional societies
• Agriculture
• Minority organizations
• Public interest organizations, and
• State or local government employee with a specialized
interest in nutrition monitoring
1990 National Nutrition Monitoring and
Related Research Act, Title III (P.L. 101-445)
© 2015 Institute of Food Technologists75
Immediacy
 Sustainability
 Resource management
(land, water, energy)
 Cultivars compatible
with climate dynamics
 Biodiversity
 Supply chain (e.g.,
grains, fish  price
stability)
 Globalization of food
supply
 R&D investment
 New technology and
innovation
 Political tension 
unstable food supply
 Food security policy
 Poverty  Inadequate
food  Decline physical
and mental development
 Rural development  
hunger
© 2015 Institute of Food Technologists76
► Urgency for public and personal health
► Urgency for collaborative funding
► Urgency for the next generation
Call to Action
“A coordinated strategic plan that includes all sectors of society, including
individuals, families, educators, communities, physicians and allied health
professionals, public health advocates, policy makers, scientists, and small and large
businesses (e.g., farmers, agricultural producers, food scientists, food
manufacturers, and food retailers of all kinds), should be engaged in the
development and ultimate implementation of a plan to help all Americans eat well,
be physically active, and maintain good health and function.
It is important that any strategic plan is evidence-informed, action-oriented, and
focused on changes in systems in these sectors” USDA
© 2015 Institute of Food Technologists77
► Must interconnect in policymaking that
extends beyond nutrition.
► Must leverage interdisciplinary expertise
that embraces knowledge, technology
and innovation plus sections outside of
the food system to achieve a more
encompassing food system
► Develop a strong evidence-based
approach to decision making
► Engage global harmonization guidelines
in regionally, culturally appropriate
practices in food supply
Going Forward
© 2015 Institute of Food Technologists78
► Need a White House conference: greater attention to
consumers
► Need to consider food forms beyond fruits and vegetables
► Need to understand everyone has a role in promoting
better food choices, while being sensitive to culture and
tradition
► Need to provide safe, nutritious, affordable and accessible
foods for everyone
► Need to encourage research funding that includes
agriculture, applied community nutrition, human behavior
across demographics, and consumer education
Going Forward
© 2015 Institute of Food Technologists79
While Diet Is Linked to Health, Much Confusion
Exists About What to Eat and Under What
Circumstances!!
© 2015 Institute of Food Technologists80
Today’s session was organized by the
Corn Refiners Association.
Thank you.
© 2015 Institute of Food Technologists
Any Questions?

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A more effective national food and nutrition policy

  • 1. More Effective National Food and Nutrition Policy: Balancing the Role of Research, Nutrition Science, and Public Health
  • 2. © 2015 Institute of Food Technologists Presenters: Joanne Slavin, PhD, RD, University of Minnesota The Widespread Effects of Food and Nutrition Policy on Public Health ► Segment takes a look back at the history of the Dietary Guidelines for Americans and how they have progressed over the past 35 years Today we will hear from… Moderator: Elizabeth Crawford Senior Correspondent, Food Navigator-USA 2
  • 3. © 2015 Institute of Food Technologists Connie M. Weaver, PhD, Purdue University The Importance and Deficiencies of Consistent, Systematic Evaluation Processes in Policymaking ► Examination of the evaluation processes used by policymakers and provided examples of how differences among these processes can lead to varying results Roger Clemens, DrPH, University of Southern California The Role of Scientific Research in Food and Nutrition Policy ► An exploration of the different types of research used to set nutrition policy and how varying strengths of this research often lead scientists to presume outcomes that may not hold true after stronger research emerges 3
  • 4. Joanne Slavin, PhD, RD Professor Department of Food Science and Nutrition University of Minnesota [email protected] The Widespread Effects of Food and Nutrition Policy on Public Health
  • 5. Disclosures for Joanne Slavin AFFILIATION/FINANCIAL INTERESTS (past 12 months) CORPORATE ORGANIZATION Grants/Research Support: American Pulse Association Scientific Advisory Board/Consultant: Tate and Lyle, Atkins, Kelloggs Speakers Bureau: Stock Shareholder: Other © 2015 Institute of Food Technologists5
  • 6. From Science to Me The Science Policy Me © 2015 Institute of Food Technologists6
  • 7. There is no perfect diet! ► Humans are omnivores, like pigs, and are adaptable to a wide range of foods ► Humans have survived and prospered on all kinds of diets, mostly reflecting access to food supply • Traditional Arctic diet: 80% of kcals from fat • Traditional African diet: 80% of kcals from carbohydrate ► Because of concerns with fat and cardiovascular disease, U.S. diet has moved from higher fat (42% of kcal in 1972) to lower fat (32% of kcal in 2000) – but more calories © 2015 Institute of Food Technologists7
  • 8. Dietary Guidance—A Historical Perspective 1894 - Dr. W.O. Atwater specified amount of protein and total calories in a good diet, but left unspecified the division of calories between fats and carbohydrates 1902 - “evils of overeating may not be felt at once, but sooner or later they are sure to appear – perhaps in general debility, perhaps in actual disease” 1902 - “ordinary food materials…make a fitting diet, and the main question is to use them in the kinds and proportions fitted to the actual needs of the body” Recommended variety, proportionality and moderation, measuring calories, and an affordable diet focused on nutrient-rich foods, less fat, sugar and starch. © 2015 Institute of Food Technologists8
  • 9. Nutritional science – nutrients to prevent deficiency diseases 1941:  National Academy of Sciences began issuing “Recommended Dietary Allowances” – quantity of nutrients a person needed to consume daily to ensure basic good health, proper growth and reproductive success, and to prevent nutrient deficiency diseases.  Nutritional deficiency diseases have been virtually eliminated in the U.S., thanks to enrichment of refined grains and other fortification strategies. © 2015 Institute of Food Technologists9
  • 10. Nutrient Adequacy  Meet nutrient needs without exceeding calorie needs  Dietary Reference Intakes (DRIs) • Acceptable Macronutrient Distribution Ranges (AMDR) - Protein: 10 - 35% of kcal - Carbohydrates: 45 - 65% of kcal - Fat: 20 - 35% of kcal • Recommended Dietary Allowance (RDA) • Adequate Intake (AI) • Tolerable Upper Level Intake (UL) © 2015 Institute of Food Technologists10
  • 11. Senate Select Committee on Nutrition and Human Needs – Dietary Goals the United States (1977) ► Increase carbohydrates to 55%–60% of energy ► Reduce fat to 30% of energy ► SF, MF, PUFAs – 10%/10%/10% ► Reduce cholesterol to 300 mg/day ► Reduce sugar consumption by 40% ► Reduce salt consumption to 3 g/day – 1200 mg sodium © 2015 Institute of Food Technologists11
  • 12. Toward Healthful Diets, FNB, 1980 “The Board expresses its concern over excessive hopes and fears in many current attitudes toward food and nutrition. Sound nutrition is not a panacea. Good food that provides appropriate proportions of nutrients should not be regarded as a poison, a medicine, or a talisman. It should be eaten and enjoyed.” © 2015 Institute of Food Technologists12
  • 13. Dietary Guidelines for Americans 1980 - 2010 1980 1985 1990 1995 2000 2005 2010 © 2015 Institute of Food Technologists13
  • 14. DGAC Advisory Report submitted to the Secretaries of USDA & HHS USDA & HHS write the Policy Document DGAC is chartered DG’s implemented through Federal programs DGAC Charter DGAC Public Meetings: Review of the Science Evidence-based Methodology Used to Review the Science Public comments encouraged/collected Dietary Guidelines for Americans, 2010 (TBD) U.S. Department of Agriculture U.S. Department of Health and Human Services www.dietaryguidelines.gov The New “Pyramid” Development of Dietary Guidelines Policy © 2015 Institute of Food Technologists14
  • 15. Total Diet 2010 DGAC Conclusions: Not Evidence-Based Key Topics:  Overweight/obese nation  Develop healthy dietary patterns in childhood and adolescence  Maintain energy intake within calorie needs  Maximize nutrient density by emphasizing whole grains, vegetables, fruits, milk/milk products, and oils  Reduce solid fats and added sugars and sodium  Flexible eating patterns © 2015 Institute of Food Technologists15
  • 16. Chapter 3 Foods and Food Components to Reduce © 2015 Institute of Food Technologists16
  • 17. Chapter 4 Foods and Nutrients to Increase © 2015 Institute of Food Technologists17
  • 18. Comparison of Consumption to Recommendations © 2015 Institute of Food Technologists18
  • 19. DGAC 2015 ► “Settled science” – may not see much change on nutrient levels ► Movement to whole foods and away from nutrients ► Topics such as sustainability, gluten, vegan diets, and food processing have been discussed and may be included in 2015 DGA © 2015 Institute of Food Technologists19
  • 20. 2015 DGAC – Dietary patterns, foods and nutrition, and health outcomes ► The US population should consume dietary patterns that are: • Rich in vegetables, fruits, whole grains, fish/seafood, legumes, and nuts • Moderate in dairy products (e.g. low and non-fat dairy) and alcohol and • Lower in red and processed meat and • Low in sugar-sweetened foods and beverages and refined grains © 2015 Institute of Food Technologists20
  • 21. 2015 DGAC – Food and nutrient intakes, and health: Current status and trends ► The US population has low intakes of certain key nutrients – vitamin D, potassium, fiber, calcium, and for females also iron. These low intakes are a public health concern because inadequate intakes are linked to health problems ► The US population over consumes sodium and saturated fat. Excess intakes of these nutrients are also linked to health problems ► Many of the food groups that are good sources of under consumed nutrients are consumed in low amounts by the US population ► Many of the food groups and food categories that have high levels of sodium, saturated fat, and added sugars are consumed in high amounts © 2015 Institute of Food Technologists21
  • 22. 1943: Basic Seven Margaret Mead: “People don’t eat nutrition – they eat food” Basic 7 did not specify the number of servings of each food group needed daily © 2015 Institute of Food Technologists22
  • 23. 1940s1950s-1960s 1970s 1992 Food for Young Children 1916 2005 Food advice: Evolution of USDA’s Food Guidance – Moderation and Variety © 2015 Institute of Food Technologists23
  • 24. MyPlate.gov (6/2/11) © 2015 Institute of Food Technologists24
  • 25. Key Takeaways ► Evidence-based reviews are limited in our ability to define “healthy foods” ► Recommendations for less added sugar and solid fats are based on empty calories, not health outcomes – USDA modeling ► Since nutrition research does not support that vegetarian diets are healthier than animal based diets, there is a movement to “sustainability” as the reason to support plant-based diets ► Solving important nutrition problems will require partnerships based on trust among academics, the government, commodity groups, and food companies © 2015 Institute of Food Technologists25
  • 26. Connie M. Weaver, Ph.D. Purdue University West Lafayette, IN [email protected] The Importance and Deficiencies of Consistent, Systematic Evaluation Processes in Policymaking
  • 27. Disclosures for Connie Weaver AFFILIATION/FINANCIAL INTERESTS (past 12 months) CORPORATE ORGANIZATION Grants/Research Support: NIH, DRI, Nestle, Tate & Lyle Scientific Advisory Board/Consultant: NOF, ILSI, Showalter, Pharmavite Speakers Bureau: Stock Shareholder: Other © 2015 Institute of Food Technologists27
  • 28. Outline ► Evidence-based approach ► Difficulties encountered with evidence-based approach in nutrition © 2015 Institute of Food Technologists28
  • 29. The Philosophy Behind an Evidence-based System ► Rules are set “up front” then followed, rather than having a preconceived idea and then finding the papers to support the idea. ► If one follows the rules, any trained scientist should come to the same conclusion. © 2015 Institute of Food Technologists29
  • 30. Hierarchy of Evidence RCT Double Blinded RCT Cohort Study Case Control Case Series Case Report Expert Opinion Weaker Evidence Stronger Evidence Evidence-based Medicine Hierarchy Consistency ends here! © 2015 Institute of Food Technologists30
  • 31. No Consistent Literature Retrieval or Grading Systems ► NIH-AHRQ ► FDA-own system for health claims ► Various other approaches Slavin Nutr J 14:15, 2015 © 2015 Institute of Food Technologists31
  • 32. Nutrition Evidence Library (NEL) Process Define Research Recommendations Dietary Guidelines Advisory Committee Since 2010: Summarize and Synthesize the Evidence •Assess quality of individual studies •Assess applicability •Summarize and synthesize evidence Develop and Grade Conclusion Statements Formulate Systematic Review Questions •Exploratory searches •Public comment •Dialogue with experts •Analytical Framework •PICO Literature Search and Sort •Identify study eligibility criteria •Determine search strategy •Search for relevant studies •List included studies •List excluded studies and rationale Extract Evidence From Studies Create evidence worksheets © 2015 Institute of Food Technologists32
  • 33. Grade Strength of Evidence ► Quality • Scientific rigor and validity • Consider study design and execution ► Quantity • Number of studies/sample sizes ► Consistency of findings across studies ► Impact • Importance of studied outcomes/magnitude of effect • Magnitude of effect ► Generalizability Grades: 1.STRONG; 2. MODERATE; 3. LIMITED © 2015 Institute of Food Technologists33
  • 34.  Search term + bone + child + adolescence  Excluded: reviews, animal studies, non-English  Subcommittees reviewed abstracts and excluded • If not RCT or observational study • No bone outcomes • Interventions <6 mo. • Drug trials of disease states ASN Scientific Statements Example of Development of Peak Bone Mass PubMed search of scientific literature Jan 2000-Dec 2014 © 2015 Institute of Food Technologists34
  • 35. Level of Evidence Description A: Strong One large, well-conducted, generalizable, RCT OR Multiple RCTs or trials with few limitations B: Moderate Multiple prospective cohort studies. OR Meta-analysis of prospective cohort studies. C: Limited Multiple prospective cohort studies from diverse populations that have limitations. OR One well-designed prospective study. OR Multiple cross-sectional or case-controlled studies with few limitations. OR Meta-analysis with design limitations. D: Inadequate Methodologic flaws OR Insufficient data. Evidence Grade © 2015 Institute of Food Technologists 35
  • 36. Differences in process for evaluating scientific evidence can lead to different conclusions Example: Choosing different end points concern over salt © 2015 Institute of Food Technologists36
  • 37. 2010 Dietary Guidelines Advisory Committee Conclusions ► A strong body of evidence has documented that in adults, as sodium intake decreases, so does blood pressure. ► A moderate body of evidence has documented that as sodium intake decreases, so does blood pressure in children, birth to 18 years of age. ► The reduction from 2,300 mg to 1,500 mg per day should occur gradually over time. [about 750 mg/1000kcal] © 2015 Institute of Food Technologists37
  • 38. IOM Committee on Consequences of Sodium Reduction in Populations – Released May 14, 2013  Calls for national action to reduce sodium content of foods - average intake 3400 mg Na/d  Evidence weak to strive for less than 2300 mg Na/d – need more studies between 1500 and 2300 mg/d Focused on disease outcomes beyond blood pressure © 2015 Institute of Food Technologists38
  • 39. 2015 DGAC Sodium Recommendations <2300 mg/day © 2015 Institute of Food Technologists39
  • 40. There is NO guarantee of consensus conclusions even if you use same process and end points © 2015 Institute of Food Technologists40
  • 41. © 2015 Institute of Food Technologists41
  • 42. What is the Relationship Between Calcium and Vitamin D and Hip Fracture? Women’s Health Initiative RCT of CaD (n=68,719 postmenopausal women) Prentice et al., Osteopor Int 24:567, 2013 • All subjects including those taking own supplements • >5 Year CaD Intervention-related Health Outcomes in Subjects Adherent & Not Taking Baseline Supplements No relationship Large benefit © 2015 Institute of Food Technologists42
  • 43. Difficulties of Applying Evidence-Based Medicine Approach to Nutrition © 2015 Institute of Food Technologists43
  • 44. Ranking of Study Type ► The RCT is given greatest weight because it is the only design that permits strong causal inference ► But for nutrition, that often means sacrificing control of the independent variable (nutrient diet) in favor of the dependent variable (health outcome) © 2015 Institute of Food Technologists44
  • 45. RCT Trials are Designed for a Compound That:  Works quickly  Usually pinpointed to 1 pathway or 1 mechanism of action  That is: a drug © 2015 Institute of Food Technologists45
  • 46. Features of RCTs for Drugs ► Tested in or applied to sick people ► Test agent is contrasted with its absence compared to a nutrient where there can be no nutrient-free state ► Sharply defined primary outcome measure ► Effect size usually large compared to a nutrient ► Response characteristic is usually monotonic across plausible intakes © 2015 Institute of Food Technologists46
  • 47. Contrasts ► Drug – drug-added state is contrasted with drug-free state ► Nutrient – “high” intake is contrasted with “low” intake © 2015 Institute of Food Technologists47
  • 48. Effect Size ► Drug- usually large ► Nutrient – usually small, but • public health impact may nevertheless be large • aggregate effect across multiple • systems is itself often large © 2015 Institute of Food Technologists48
  • 49. Consequence ► When changes are small, testing for isolated nutrient effects requires large, expensive, lengthy studies if effects in isolated systems are to be found statistically significant. © 2015 Institute of Food Technologists49
  • 50. INTAKE EFFECT Study Design & the Threshold the control group must be deficient © 2015 Institute of Food Technologists50
  • 51. The Ethical Problem ► Placing the control group on a clearly inadequate intake © 2015 Institute of Food Technologists51
  • 52. Underreporting error for energy intake in overweight boys and girls was 35+18% EIas%ofTEE Girls Boys Reported EI Weight adjusted MEI TEE by DLW Singh, 89(6):1744-1750, 2009 Concern with Diet Assessment for Observational Studies © 2015 Institute of Food Technologists52
  • 53. Controlled Feeding Studies ► Historically ranked highest for evidence for nutrients/diet ► Minimizes confounders and allows study of range of known intakes © 2015 Institute of Food Technologists53
  • 54. Animal Studies ► Can have controlled diet and sufficiently long duration for cancer outcome measures. • But relevance to humans? ► Invasive procedures ► Mechanistic © 2015 Institute of Food Technologists54
  • 55. Future Needs ► Good biomarkers are the most needed tool in research related to diet and health. Current biomarkers for intake and health outcome measures range from weak to moderately good. Even the better ones need validation. © 2015 Institute of Food Technologists55
  • 56. Kinds of Evidence Basic Research Translational Research Efficacy Studies Effectiveness Research How does it work? Can it be studied in people? Specific effects? How good is the translation? © 2015 Institute of Food Technologists56
  • 57. Best recommendations use the totality of evidence with liberal doses of critical thinking and LOGIC! © 2015 Institute of Food Technologists57
  • 58. The Role of Scientific Research in Food and Nutrition PolicyRoger Clemens, DrPH, CFS, CNS, FACN, FIFT, FIAFST Adjunct Professor, Pharmacology and Pharmaceutical Sciences USC School of Pharmacy, Los Angeles [email protected] The Role of Scientific Research in Food and Nutrition Policy
  • 59. Disclosures for Roger Clemens AFFILIATION/FINANCIAL INTERESTS (past 12 months) CORPORATE ORGANIZATION Grants/Research Support: None Scientific Advisory Board/Consultant: Spherix Consulting, Mushroom Council, Almond Board of California, California Walnut Commission, Abbott Nutrition, FMC, Numerous Law Firms Speakers Bureau: IFT, ASN Stock Shareholder: None Other Daedalus Humanitarian/Foundation © 2015 Institute of Food Technologists59
  • 60. ► Improve health through food ► Provide food that is safe, nutritious, affordable and accessible ► Implement consistent policy ► Establish dietary clear guidelines Dietary Guidelines and Global Imperatives • Need health literacy • Need developmental approach to dietary guidelines • Need to recognize nutrition needs throughout life cycle • Need applied research based on food • Need public/private partnerships • Need to shift cultures of health © 2015 Institute of Food Technologists60
  • 61. ► Over 35 years, increased prevalence of NCD ► Medical expenses associated with obesity: $200-300B ► > $100B spent on nutrition assistance programs ~ 70% of SNAP support families with children ► ~24MM people in low income ► ~20% children are food insecure ► Food and inactivity leading contributors of death in the USA J. Michael McGinnis, M.D., M.A., M.P.P., IOM Senior Scholar, May 21, 2015 ► Agriculture is responsible for much of the progress humanity has made against hunger. The only way that the world can keep up with food production is by the improvement of science and technology. Norman Borlaug, Nobel Laureate, 1970 Health Today © 2015 Institute of Food Technologists61
  • 62. ► Examine the Dietary Guidelines for Americans, 2010 and determine topics for which new scientific evidence is likely to be available that may inform revisions to the current guidance or suggest new guidance. ► Place its primary focus on the systematic review and analysis of the evidence published since the last DGAC deliberations. ► Place its primary emphasis on the development of food-based recommendations that are of public health importance for Americans ages 2 years and older. ► Prepare and submit to the Secretary of Health and Human Services and the Secretary of Agriculture a report of technical recommendations, with rationales, to inform the development of the 2015 Dietary Guidelines for Americans. DGAC responsibilities include providing authorship for this report; however, responsibilities do not include translating the recommendations into policy or into communication and outreach documents or programs. Charge to the 2015 DGAC http://www.health.gov/dietaryguidelines/2015-binder/2015/chargeCommittee.aspx June 2013 © 2015 Institute of Food Technologists62
  • 63. Assessing the Evidence ► Observational claims are not necessarily validated via clinical trials. ► Clinical studies among small populations do not necessarily translate to total population (think public policy) ► Common words like “association,” “related,” and “relative risk” imply strength, yet upon review the work is generally quite weak ► “Definitive solution will not come from another million observational papers or a few small randomized trials” Ioannidis JPA BMJ 2013;347: doi: 10.1136/bmj.f6698 © 2015 Institute of Food Technologists63
  • 64. ► Systematic reviews and meta-analyses • Different inclusion/exclusion criteria impact results • Different statistical approaches and choices of covariates impact results • Dietary exposures are not accurate • Associations  Causes • Reflect the perspectives of others Research Bias Nicklas et al., J Nutr 2014; doi: 10.3945/jn.114.194068 © 2015 Institute of Food Technologists64
  • 65. It is…important to not be distracted by questions that we have not been asked to address. What was Asked? What’s missing in many [meta analysis and systematic review] studies published since 2010 DGAC?  Undefined and inconsistent outcomes  Intention to treat analysis  Complete case analysis  Unexplained discontinuances  Imputed baseline data extended beyond current analysis  Multiple imputations in analyses © 2015 Institute of Food Technologists65
  • 66. Kaiser et al. Obes Rev 2013; doi: 10.1111/obr.12048. Ecological Relation of Water Intake with Prevalence of Overweight/Obesity: 1961-2000 Rise in obesity rates (round markers) and bottled water consumption (square markers). USA © 2015 Institute of Food Technologists66
  • 67. Consumer Confusion Confidence Confusion IFIC 2012: • Three out of four consumers feel that changes in nutritional guidance makes it hard to know what to believe • Half believe it is easier to do their own taxes than to figure out how to eat healthfully International Food Information Council Foundation 2012 Food & Health Survey . Consumer Attitudes Toward Food Safety, Nutrition & Health http://www.foodinsight.org/Content/3840/2012%20IFIC%20Food%20and%20Health%20Survey%20Repo rt%20of%20Findings%20(for%20website).pdf © 2015 Institute of Food Technologists67
  • 68. Do Scripted Diets Work for Policy? What about Low-fat Diets? 2015 DGAC Meeting 5, September 16, 2014 © 2015 Institute of Food Technologists68
  • 69. Comments ► Chowdhury: “My take on this would be that it’s not saturated fat that we should worry about” in our diets. ► Hu: The findings should not be taken as “a green light” to eat more steak, butter and other foods rich in saturated fat. … looking at individual fats and other nutrient groups in isolation could be misleading, because when people cut down on fats they tend to eat more bread, cold cereal and other refined carbohydrates that can also be bad for cardiovascular health. ► Hu: “The single macronutrient approach is outdated. I think future dietary guidelines will put more and more emphasis on real food rather than giving an absolute upper limit or cutoff point for certain macronutrients.” ► Hu: People should try to eat foods that are typical of the Mediterranean diet, like nuts, fish, avocado, high-fiber grains and olive oil. Rajiv Chowdhury, PhD Cardiovascular Epidemiologist University of Cambridge Frank Hu, MD, PhD Professor of Nutrition and Epidemiology Harvard University http://acsh.org/2014/03/huge-new-re-evaluation-saturated-fat-heart-risk-finds-link/ March 18, 2014 © 2015 Institute of Food Technologists69
  • 70. ► Cholesterol is not a nutrient of concern for overconsumption. ► Saturated fat is still a nutrient of concern for overconsumption, particularly for those older than the age of 50 years. Dietary Cholesterol and Saturated Fat © 2015 Institute of Food Technologists70
  • 71. ► There is insufficient evidence that an exchange of sugar for non-sugar carbohydrates results in lower body weights (a calorie = a calorie) ► Observational (cross-sectional) studies suggest a possible relationship between consumption of sugar- sweetened beverages (SSB) and body weight; no supporting RCTs ► Insufficient evidence to support a difference between liquid and solid sugar intake and body weight control Added Sugars and Body Weight Key reference: van Baak & Astrup. Obes Rev 2009; 10 Suppl 1:9-23 © 2015 Institute of Food Technologists71
  • 72. Agency Statement 2010 DGAC RCTs report that added sugars are not different from other calories in increasing energy intake or body weight. Systematic reviews in this area are also inconsistent. EFSA 2012 …a cause and effect relationship has not been established between total sugar intake and body weight gain WHO 2015 (Te Morenga et al, 2014) ‘Trials in children, which involved recommendations to reduce intake of sugar sweetened foods and beverages, had low participant compliance to dietary advice; these trials showed no overall change in body weight.’ German Nutrition Society 2012 In general, meta-analyses are inconsistent. The most recent meta-analysis concludes that the risk-increasing effect is limited to individuals with initially already increased BMI or existing overweight, respectively Sugar in Context © 2015 Institute of Food Technologists72
  • 73. Food, Nutrition & Health • Secondary Education Challenge • Community Food Projects • Higher Education Challenge • 1890 Capacity • Food Safety, AFRI • Climate Variability and Change, AFRI • Food Security, AFRI • Foundational Program, AFRI • Alaska Native & Native Hawaiian Institutions • Federally Recognized Tribes Extension Program • Hispanic-Serving Institutions Education • Multicultural Scholars • National Needs Graduate Fellowships • New Technologies for Ag Extension • Rural and Community Development, SBIR • Tribal Colleges Education Equity • Tribal Colleges Extension • Tribal Colleges Research © 2015 Institute of Food Technologists73
  • 74. ► FDA Investment • Further scientific knowledge about potential food hazards • Expand on best safety practices • Better understand how consumers access, prepare, and use the foods they serve and eat ► CFSAN Research Strategic Plan • Globalization of the food supply chain • Changing industry processes • Consumer preferences for fresh and minimally processed foods Science & Research (Food) Where’s Food Science and Nutrition? Where’s Agriculture? © 2015 Institute of Food Technologists74
  • 75. ►Criteria for NNMAC representation (Title II) – At least two representatives selected solely on basis of established record of distinguished service and eminence in many disciplines and fields (>20) • Various geographical areas • Private sector • Academia • Scientific and professional societies • Agriculture • Minority organizations • Public interest organizations, and • State or local government employee with a specialized interest in nutrition monitoring 1990 National Nutrition Monitoring and Related Research Act, Title III (P.L. 101-445) © 2015 Institute of Food Technologists75
  • 76. Immediacy  Sustainability  Resource management (land, water, energy)  Cultivars compatible with climate dynamics  Biodiversity  Supply chain (e.g., grains, fish  price stability)  Globalization of food supply  R&D investment  New technology and innovation  Political tension  unstable food supply  Food security policy  Poverty  Inadequate food  Decline physical and mental development  Rural development   hunger © 2015 Institute of Food Technologists76
  • 77. ► Urgency for public and personal health ► Urgency for collaborative funding ► Urgency for the next generation Call to Action “A coordinated strategic plan that includes all sectors of society, including individuals, families, educators, communities, physicians and allied health professionals, public health advocates, policy makers, scientists, and small and large businesses (e.g., farmers, agricultural producers, food scientists, food manufacturers, and food retailers of all kinds), should be engaged in the development and ultimate implementation of a plan to help all Americans eat well, be physically active, and maintain good health and function. It is important that any strategic plan is evidence-informed, action-oriented, and focused on changes in systems in these sectors” USDA © 2015 Institute of Food Technologists77
  • 78. ► Must interconnect in policymaking that extends beyond nutrition. ► Must leverage interdisciplinary expertise that embraces knowledge, technology and innovation plus sections outside of the food system to achieve a more encompassing food system ► Develop a strong evidence-based approach to decision making ► Engage global harmonization guidelines in regionally, culturally appropriate practices in food supply Going Forward © 2015 Institute of Food Technologists78
  • 79. ► Need a White House conference: greater attention to consumers ► Need to consider food forms beyond fruits and vegetables ► Need to understand everyone has a role in promoting better food choices, while being sensitive to culture and tradition ► Need to provide safe, nutritious, affordable and accessible foods for everyone ► Need to encourage research funding that includes agriculture, applied community nutrition, human behavior across demographics, and consumer education Going Forward © 2015 Institute of Food Technologists79
  • 80. While Diet Is Linked to Health, Much Confusion Exists About What to Eat and Under What Circumstances!! © 2015 Institute of Food Technologists80
  • 81. Today’s session was organized by the Corn Refiners Association. Thank you. © 2015 Institute of Food Technologists Any Questions?