The document outlines the AIISC's research initiatives in social good and harm, focusing on public health, epidemiology, and social media analysis, particularly concerning harassment detection and substance abuse trends. It highlights various interdisciplinary projects, proposals, and methodologies using AI and big data to address issues such as mental health, addiction, and online extremism. Key areas of interest include the nuanced impacts of social media, biases in AI, and technological advancements in understanding public health challenges.