Antileprotic drugs
• Which of the following antitubercular drugs
is safe in hepatitis?
• (a) Isoniazid
• (b) Rifampicin
• (c) Pyrazinamide
• (d) Ethambutol
• A diabetic patient develops cellulitis due to
Staphylococcus aureus that was found to be
methicillin resistant on the antibiotic sensitivity
testing. All of the following antibiotics will be
appropriate EXCEPT:
• (a) Vancomycin
• (b) Imipenem
• (c) Teicoplanin
• (d) Linezolid
• Prolonged treatment with INH leads to
deficiency of?
• (a) Pyridoxine
• (b) Thiamine
• (c) Pantothenic acid
• (d) Niacin
• Commonest side effect of Dapsone is:
• (a) Hemolytic anemia
• (b) Thrombocytopenia
• (c) Cyanosis
• (d) Bone marrow depression
• Ethambutol causes
• (a) Retrobulbar neuritis
• (b) Deafness
• (c) Red urine
• (d) Peripheral neuritis
• In leprosy, the best bactericidal agent is:
• (a) Clofazimine
• (b) Dapsone
• (c) Rifampicin
• (d) Ethionamide
• A patient suffering from AIDS is on zidovudine,
lamivudine and indinavir therapy. He develops
pulmonary tuberculosis for which treatment is
started. Which of the following should be
avoided in him?
• (a) INH
• (b) Ethambutol
• (c) Pyrazinamide
• (d) Rifampicin
• The primary reason for the use of drug
combination in the treatment of tuberculosis is
to:
• (a) Ensure patient compliance with the drug
regimen
• (b) Enhance activity against metabolically inactive
• mycobacteria
• (c) Delay or prevent the emergence of resistance
• (d) Provide prophylaxis against other bacterial
infections
• ATT causing orange coloured urine is
• (a) Rifampicin (DNB 2002, 2005)
• (b) Isoniazid
• (c) Streptomycin
• (d) Pyrazinamide
• Which of the following antitubercular drug is
not hepatotoxic
• (a) Isoniazid
• (b) Rifampicin
• (c) Ethionamide
• (d) Streptomycin
• Corticosteroids are absolutely
contraindicated in the following type of
tuberculosis:
• (a) Miliary
• (b) Meningeal
• (c) Intestinal
• (d) Renal
• A patient of multidrug resistant tuberculosis is
on antitubercular drugs. After a few months he
develops an inability to distinguish between red
and green color. Most likely drug causing these
symptoms is:
• (a) Rifampicin
• (b) Ethambutol
• (c) Cycloserine
• (d) Ethionamide
• In Lepra reaction, the drug useful is:
• (a) Pencillins
• (b) Clofazimine
• (c) Dapsone
• (d) Rifampicin
MCQ

Antileprotic drugs

  • 1.
  • 14.
    • Which ofthe following antitubercular drugs is safe in hepatitis? • (a) Isoniazid • (b) Rifampicin • (c) Pyrazinamide • (d) Ethambutol
  • 15.
    • A diabeticpatient develops cellulitis due to Staphylococcus aureus that was found to be methicillin resistant on the antibiotic sensitivity testing. All of the following antibiotics will be appropriate EXCEPT: • (a) Vancomycin • (b) Imipenem • (c) Teicoplanin • (d) Linezolid
  • 16.
    • Prolonged treatmentwith INH leads to deficiency of? • (a) Pyridoxine • (b) Thiamine • (c) Pantothenic acid • (d) Niacin
  • 17.
    • Commonest sideeffect of Dapsone is: • (a) Hemolytic anemia • (b) Thrombocytopenia • (c) Cyanosis • (d) Bone marrow depression
  • 18.
    • Ethambutol causes •(a) Retrobulbar neuritis • (b) Deafness • (c) Red urine • (d) Peripheral neuritis
  • 19.
    • In leprosy,the best bactericidal agent is: • (a) Clofazimine • (b) Dapsone • (c) Rifampicin • (d) Ethionamide
  • 20.
    • A patientsuffering from AIDS is on zidovudine, lamivudine and indinavir therapy. He develops pulmonary tuberculosis for which treatment is started. Which of the following should be avoided in him? • (a) INH • (b) Ethambutol • (c) Pyrazinamide • (d) Rifampicin
  • 21.
    • The primaryreason for the use of drug combination in the treatment of tuberculosis is to: • (a) Ensure patient compliance with the drug regimen • (b) Enhance activity against metabolically inactive • mycobacteria • (c) Delay or prevent the emergence of resistance • (d) Provide prophylaxis against other bacterial infections
  • 22.
    • ATT causingorange coloured urine is • (a) Rifampicin (DNB 2002, 2005) • (b) Isoniazid • (c) Streptomycin • (d) Pyrazinamide
  • 23.
    • Which ofthe following antitubercular drug is not hepatotoxic • (a) Isoniazid • (b) Rifampicin • (c) Ethionamide • (d) Streptomycin
  • 24.
    • Corticosteroids areabsolutely contraindicated in the following type of tuberculosis: • (a) Miliary • (b) Meningeal • (c) Intestinal • (d) Renal
  • 25.
    • A patientof multidrug resistant tuberculosis is on antitubercular drugs. After a few months he develops an inability to distinguish between red and green color. Most likely drug causing these symptoms is: • (a) Rifampicin • (b) Ethambutol • (c) Cycloserine • (d) Ethionamide
  • 26.
    • In Leprareaction, the drug useful is: • (a) Pencillins • (b) Clofazimine • (c) Dapsone • (d) Rifampicin
  • 27.