Accurate crop yield prediction is critical for enhancing food security, particularly in agrarian economies prone to soil degradation and climatic uncertainties. This study explores the application of Support Vector Regression (SVR) for forecasting wheat yields in Uzbekistan, utilizing soil fertility indicators as key predictive features. Unlike conventional linear regression models, SVR effectively captures complex non-linear interactions between soil physicochemical properties and crop productivity, thereby offering improved adaptability to real-world agricultural conditions. The dataset comprises essential soil attributes, including nitrogen (N), phosphorus (P), potassium (K), pH, organic carbon (OC), electrical conductivity (EC), and micro-nutrient concentrations. Data preprocessing involved feature standardization, K-nearest neighbor (KNN) imputation for handling missing values, and correlation analysis to select the most influential variables. The dataset was partitioned using an 80/20 stratified split, and the SVR model with a radial basis function (RBF) kernel was optimized through 5-fold cross-validation and exhaustive grid search for hyperparameter tuning. The optimized SVR model achieved a coefficient of determination (𝑅2) of 0.87 and demonstrated a low root mean square error (RMSE), outperforming baseline regression methods. Model interpretability was enhanced using SHapley Additive exPlanations (SHAP), which identified soil pH, organic carbon, and available phosphorus as the most significant predictors of wheat yield—findings consistent with established agronomic principles. Overall, the results confirm SVR’s potential as a robust, scalable, and interpretable tool for precision agriculture, offering practical insights for site-specific yield forecasting and promoting sustainable land management practices in Uzbekistan.