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Atropisomerism

KOTA COLLEGE OF PHARMACY discusses atropisomerism in biphenyl compounds, which are stereoisomers where rotation is hindered about a single bond, resulting in isomers with differing stability due to steric strain or a rotational barrier, allowing the isomers to be isolated individually.

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KOTA COLLEGE OF PHARMACY Atropisomerism in biphenyl compounds Mr. Pradeep Swarnkar Associate Professor
• Atropisomers are the stereoisomers in which rotation hindered about a single bond. • The isomers have difference energy of stability due to steric strain or a barrier to rotation. • The stability of the structure allow isomers to isolation individually.
Atropisomerism
Atropisomerism
Atropisomerism
Atropisomerism

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Atropisomerism

  • 1.
    KOTA COLLEGE OF PHARMACY Atropisomerismin biphenyl compounds Mr. Pradeep Swarnkar Associate Professor
  • 3.
    • Atropisomers arethe stereoisomers in which rotation hindered about a single bond. • The isomers have difference energy of stability due to steric strain or a barrier to rotation. • The stability of the structure allow isomers to isolation individually.