1
◗ Mechanical Ventilation is ventilation of the
lungs by artificial means usually by a
machine called ventilator.
◗ Aventilator delivers gas to the lungs with
either negative or positive pressure.
2
◗ Negative pressure
ventilation
Iron lung
Chest cuirase
◗ Positive pressure
ventilation
Invasive
Non invasive 3
1. Relieve respiratory distress
2. Decrease work of breathing
3. Improve pulmonary gas
exchange
4. Reverse respiratory muscle
fatigue
5. Permit lung healing
4
 Pressur
e
 Volume
 Flow
 Time
5
◗ Control -the mechanical breath goal, ie, a
set pressure or a set volume
◗ Trigger -Variable which starts inspiration
Limit - the maximum permitted value during
inspiration.
◗ Cycle - Variable which ends inspiration
6
7
Breath
types
• Mandatory breath
Ventilator does the work
Ventilator controls start and end of
inspiration
• Assist control breath
patient triggers the breath
Venti. Delivers the breath as per control
variable
• Spontaneously Supported
breath Pt. triggers the breath
Ventilator delivers pressure
support
• Spontaneous
Patient takes on
8
◗ Indications for ventilator support present
◗ Non-invasive v/s Invasive ventilation
◗ Pressure v/s Volume ventilation
◗ Extent (Partial v/s Full) & mode of
ventilation
◗ Key Ventilatory settings
◗ Appropriate Alarms and Back-up values
◗ Weaning
◗ Patient not breathing
◗ Patient breathing, …….but not enough
◗ Patient breathing enough, …….but
hypoxemic / hypercapneic
◗ Patient breathing with normal gas
exchange, ….but working hard
◗ Airway protection
◗ Clinical deterioration
◗ Hypoxia : pO2<60mm Hg
◗ Hypercarbia : pCO2 > 50mm Hg
◗ Tachypnea : RR >35
◗ Tidal volume <3-5 ml/kg
◗ Max. inspiratory pressure <-20 cm
H2O
Non- invasive ventilation
CPAP /BiPAP
◗ Patient continuously receives a set
air pressure, during both
inspiration and expiration.
◗ Patient has full control over
respiratory rate, inspiratory time ,
and depth of inspiration.
◗ This provides a set inspiratory pressure and a
different set of expiratory pressure
◗ Initial setting:
EPAP:5cm H2O
IPAP: 8cm H2O
O2 @ 2-5 L/min
Final IPAP pressures
of 15 to 22 cm H2O
are
common
◗ Patient has full control over the
respiratory rate, inspiratory time and
depth of inspiration
◗ IPAP & EPAP can be increased by
increments of 2
◗ BiPAP = CPAP + Pressure support during
inspiration
1.Cardiogenic pulmonary edema , exacerbation
of COPD , Post-op respiratory failure.
2.Neuromuscular disease with
respiratory muscle weakness, OSA.
3.Terminallyill patients
compromised patients.
4 Weaning mode.
&
Immuno
Advantages:
1 Complications of intubation –avoided
2 Allows speech ,feeding
Disadvantages:
1.Respiratory drive and intact upper
airway
2.Cannot protect airway and
does not provide full 100% ventillatory support
3. Claustrofobia & uncomfortable
for patients
◗ Improvement in:
1. Respiratory rate and heart rate
2. Dyspnea
3. Oxygen requirement
4. Hypercarbia
 Provides all the energy for Alveolar Ventilation
 Every breath is fully supported by the ventilator
 In classic control modes, patients are unable to
breathe except at the controlled set rate
 In newer control modes, machines may act in
assist-control, with a minimum set rate and all
triggered breaths above that rate are also fully
supported.
 Ensures that patient is not required to do any
Work Of Breathing
When to Consider:
◗ Spontaneously breathing patient.
◗ Comfortably provide a portion of their
required minute volume
◗Useful for weaning patients from MV support
When not to consider:
◗ Should be avoided in case of patients with
ventilatory muscle fatigue
PRESSURE VOLUME
Tidal Volume Variable Constant
Peak Ins Pressure Constant Variable
Dys-synchrony Less More likely
Barotrauma Less More likely
Flow Pattern Decreasing Preset
◗ Balance CO2 removal v/s lung protection
◗ If CO2 clearance more important than lung
protection, use volume.
◗ If lung protection is more important than
CO2 removal use PRESSURE
◗ If patient triggered ventilation, synchrony
may be enhanced with PRESSURE
◗ The ventilator delivers a preset TV at a specific R/R
and inspiratory flow rate.
◗ It is irrespective of patients’ respiratory efforts.
◗ In between the ventilator delivered breaths the
inspiratory valve is closed so patient doesn’t take
additional breaths.
◗ PIP developed depends on lung compliance and
respiratory passage resistance.
◗ Ventilator gives pressure limited, time cycled
breaths thus preset inspiratory pressure is
maintained.
◗ Decelerating flow pattern.
◗ Peak airway/alveolar pressure is controlled but TV,
minute volume & alveolar volume depends on
lung compliance, airway resistance, R/R & I:E ratio.
◗ Ventilator assists patient’s initiated breath, but if
not triggered, it will deliver preset TV at a preset
respiratory rate (control).

patient
(control)
◗ If R/R
triggered (assist) or time triggered
> preset rate, ventilator will assist,
otherwise it will control the ventilation.
◗ Ventilator delivers either assisted breaths at the
beginning of a spontaneous breath or time
triggered mandatory breaths.
◗ Synchronization window- time interval just prior
to time triggering.
◗ Breath stacking is avoided as mandatory breaths
are synchronized with spontaneous breaths.
◗ In between mandatory breaths patient is
allowed to take spontaneous breath at any TV.
◗ Patient is spontaneously breathing
◗ The vent augments the patient’s
respiratory effort with a “pressure support”
◗ Tidal Volume is determined by patient’s effort
and respiratory system compliance
◗ Can set a FiO2 PEEP and PS above PEEP
◦ Can not set respiratory rate
except back-up apnea rate.
◗ FiO2
◗ Tidal Volume /Pressure
◗ Respiratory Rate
◗ PEEP
◗ Flow Rate
◗ I:E Ratio
◗ Trigger
Start with FiO2 =1.0 and titrate to SpO2
>=94%
ABG after 20-30min
Goal –PaO2 between 60 –100 mmHg
If FiO2 requirement is>0.5 , increase PEEP
FiO2 =1.0, before & after suction,
during bronchoscopy, & any other risky
procedure
◗ The tidal volume is the amount of air delivered with each breath.
◗ Initial tidal volumes should be 8-10ml/kg, depending
on patient’s body habitus.
◗ If patient is in ARDS consider tidal volumes between 4 –
6 ml/kg with increase in PEEP
◗ In Pressure-Targeted modes you’ll set the Pressure High (PH)
according to the delivered tidal volume
◗ Males: IBW = 50 kg + 2.3 kg for
each inch over 5 feet.
◗
Females: IBW = 45.5 kg + 2.3 kg
for each inch over 5 feet.
 An optimal method for setting the
respiratory rate has not been established.
◗ 12 - 15/Min – Adult
20+_ 3 -
Child
30- 40 - New
born
On somemachines you set the
Inspiratory Time (Ti) and Expiratory Time (Te)
◗ Increase RR –
Hypoxia
Hypercapnoea / Resp. Acidosis
◗ Decrease RR-
Hypocapnoea
Resp. Alkalosis
Asthma / COPD
•Minute Ventilation (L/min) = RR
(b/min) x Tidal Volume (liters)
•If you decrease one or both the MV will
decrease resulting inHypercapnia
•Tolerated in status asthmaticus and
ARDS/ALI – Called “permissive hypercapnea”
◗ A typical initial PEEP applied is 5 cmH2O.
◗
Adjust up by increments of 2 for
marked hypoxia
◗ However, up to 20 cm H2O used in ARDS
◗ PEEP increases intra thoracic pressure and can
thus decrease venous return and thus Blood
Pressure
 Improves oxygenation
Recruits Lung in ARDS
Prevents collapse of alveoli
Diminishes the work of breathing
◗ Peak flow rates of 60 L per minute
◗ Higher rates are frequently necessary in
Asthma or those with air hunger
◗
An insufficient peak flow rate is
characterized by dysnoea, spuriously low peak
inspiratory pressures, and scalloping of the
inspiratory pressure tracing
◗ Pressure-Targeted modes allow patient to
dictate the flow rate that they want
◗ During spontaneous breathing, the normal I:E
ratio is 1:2.
◗ If exhalation time is too short “breath stacking”
occurs resulting in an increase in end-expiratory
pressure also called auto-PEEP.
◗ Asthma/COPD 1:3, 1:4, …
◗ Severe hypoxia ARDS 1:1, 2:1,
◗ Most frequently used to obtain an estimate of
Plateau pressure and static compliance
◗ Patient should not be actively breathing
◗ When used with each breath,
improves distribution of air, V/Q ratio.
◗
Pressure triggering -1to -2cm H2O
Ventilator-delivered breath is initiated if
the demand valve senses a
negative airway pressuredeflection
greater than thetrigger
sensitivity.
◗ Flow triggering 1 to 3 L/ min (preferred)
Continuous flow of gas through the ventilator
circuit is monitored. A ventilator delivered
breath is initiated when the return flow is less
than the delivered flow
•different medications for sedation.
•Opiates (morphine, fentanyl)
Benzodiazepines (Midazolam)
• Propofol
• Less is sometime more
• Paralysis without sedation = Torture
Atracurium,Vecuronium can be used
•All one needs in this situation is chemical
weakening…
• Low pressure,
• High pressure limit and alarm
• Volume alarm(low TV, high and low minute
ventilation)
• High respiratory rate alarm
• Apnea alarm and apnea values
• High/low temperature alarm
• I:E ratio limit and alarm
Complications of positive
pressure ventilation
Increase in positive airway pressure
● High intrathorasic pressure
● this pressure transmitted to airway,alveoli,as
as mediastinum and great vessels
● Compression of great vessels
●Decreased venous return
Decreased strock volume and
D c ease
oxy n elivecrayrdiac
oHuytppoutetnsion
ec eased r na lood
fl
decreased GFR
29
decreased urine
output51
Weaning
The process of withdrawing mechanical
ventilatory support and transferring the work
of breathing from the ventilator to patient.
5
2

Improvement of the cause of
respiratory failure
 Absence of major system dysfunction
 Appropriate level of oxygenation
Adequate ventilatory status

Intact airway protective mechanism
(needed for extubation)
53
Rapid Shallow Breathing Index
• Failure of weaning may be related to the
development of a spontaneous breathing pattern that
is rapid (high frequency) and shallow (low tidal
volume).
• The rapid shallow breathing index (RSBI) or
f/VT index has been used to evaluate the
effectively of the spontaneous breathing pattern.
• Favourable RSBI is < 105
54
◗
No one or method of weaning has
been definitely found to be superior;
◗ Spontaneous Breathing Trial
◗ Pressure Support Ventilation
◗ Other Modes of Partial Ventilatory Support




SIMV
Volume support (VS) and volume-assured pressure
support (VAPS)
Mandatory minute ventilation (MMV)
Airway pressure-release ventilation (APRV)
55
PROCEDU
Steps RE
PSV 1.PSV may be used in conjunction with spontaneous breathing or
SIMV mode;
2.Start PSV at a level of 5 to 15 cm H2O (up to 40 cm H2O) to
augment spontaneous VT until a desired VT (10 to 15 mL/kg)
or spontaneous frequency (<25/min) is reached;
3.Decrease pressure support (PS) level by 3 to 6 cm H2O intervals
until a level of close to 5 cm H2O is reached;
4.If patient tolerates step (3), consider extubation when blood gases
and vital signs are satisfactory.
56
What after
weaning
• Oxygen therapy
• Close monitoring: ABGs evaluation,
Pulse oximetry
• Bronchodilator therapy
• Chest physiotherapy
• Adequate nutrition, hydration, and
humidification
• Incentive spirometry 57
Trouble Shooting
58
59
• The ETT must be repositioned and re-secured at least
once a shift to prevent tissue breakdown
• Mouth care needs to be performed routinely
• Cuff pressure needs to be assessed once a shift
• Sometimes a higher pressure is needed to seal (ETT is
too small, anatomical differences)
• Check for proper inflation, determine the location
of the leak, assess the integrity of the pilot line
• Suctioning
Management of the tube
Evaluating for Leaks
• Every ventilator check must include assessing the
circuit integrity
• PIP and Vt measurements are lower than
previous measurements
• Start at the patient connection and work back to
the ventilator
• May need to disconnect the patient and
provide manual ventilation while testing the
circuit
60
◗ Check plateau pressures by allowing
an inspiratory pause (this gives you the
pressure
in the lung itself without the addition of
resistance)
pressures are low then you have
an obstruction

◗ If both peak pressures and plateau pressures
are high then you have a lung compliance
issue
◗ High peak pressure differential:
High Peak Pressures
Low Plateau Pressures
High Peak Pressures
High Plateau Pressures
Mucus Plug
Bronchospasm
ET tube blockage
Biting
ARDS
Pulmonary Edema
Pneumothorax
ET tube migration to a
single bronchus
Effusion
◗ Increase in patient agitation and dis-
synchrony on the ventilator:
◦ Could be secondary to overall discomfort
• Increase sedation
◦ Could be secondary to feelings of air
hunger
• Options include increasing tidal volume, increasing
flow rate, adjusting I:E ratio, increasing sedation
• Early use of NPPV
•Prepare and expect hypotension during
intubation – IVF bolus
•Mechanical Ventilation Strategy –
Permissive Hypercapnia
• Ventilator maneuvers that
prolong I:E
– Low tidal volumes, low respiratory rates,
square wave forms, high flow rates.
• Tidal Volumes: 6-7 ml/kg (IBW)
• Respiratory Rate: 8-10 bpm
• Flow Rate: 80-100 L/min
• Square Wave forms
• SEDATION: propofol,fentanyl
• Last resort: chemical weakening
• Expect high peak pressures
◗ Lung Protective Strategy
◗ Low-Tidal Volumes
◗ Start at 6 mL/kg IBW
◗ Goal of 4-6 mL/kg IBW
◗ Low Plateau Pressures – Less than 30
◗ High PEEP
◗ Permissive hypercapnia
Basics of Mechanical Ventilation in hospital.pptx

Basics of Mechanical Ventilation in hospital.pptx

  • 1.
  • 2.
    ◗ Mechanical Ventilationis ventilation of the lungs by artificial means usually by a machine called ventilator. ◗ Aventilator delivers gas to the lungs with either negative or positive pressure. 2
  • 3.
    ◗ Negative pressure ventilation Ironlung Chest cuirase ◗ Positive pressure ventilation Invasive Non invasive 3
  • 4.
    1. Relieve respiratorydistress 2. Decrease work of breathing 3. Improve pulmonary gas exchange 4. Reverse respiratory muscle fatigue 5. Permit lung healing 4
  • 5.
  • 6.
    ◗ Control -themechanical breath goal, ie, a set pressure or a set volume ◗ Trigger -Variable which starts inspiration Limit - the maximum permitted value during inspiration. ◗ Cycle - Variable which ends inspiration 6
  • 7.
  • 8.
    Breath types • Mandatory breath Ventilatordoes the work Ventilator controls start and end of inspiration • Assist control breath patient triggers the breath Venti. Delivers the breath as per control variable • Spontaneously Supported breath Pt. triggers the breath Ventilator delivers pressure support • Spontaneous Patient takes on 8
  • 9.
    ◗ Indications forventilator support present ◗ Non-invasive v/s Invasive ventilation ◗ Pressure v/s Volume ventilation ◗ Extent (Partial v/s Full) & mode of ventilation ◗ Key Ventilatory settings ◗ Appropriate Alarms and Back-up values ◗ Weaning
  • 10.
    ◗ Patient notbreathing ◗ Patient breathing, …….but not enough ◗ Patient breathing enough, …….but hypoxemic / hypercapneic ◗ Patient breathing with normal gas exchange, ….but working hard ◗ Airway protection
  • 11.
    ◗ Clinical deterioration ◗Hypoxia : pO2<60mm Hg ◗ Hypercarbia : pCO2 > 50mm Hg ◗ Tachypnea : RR >35 ◗ Tidal volume <3-5 ml/kg ◗ Max. inspiratory pressure <-20 cm H2O
  • 12.
  • 13.
    ◗ Patient continuouslyreceives a set air pressure, during both inspiration and expiration. ◗ Patient has full control over respiratory rate, inspiratory time , and depth of inspiration.
  • 14.
    ◗ This providesa set inspiratory pressure and a different set of expiratory pressure ◗ Initial setting: EPAP:5cm H2O IPAP: 8cm H2O O2 @ 2-5 L/min Final IPAP pressures of 15 to 22 cm H2O are common
  • 15.
    ◗ Patient hasfull control over the respiratory rate, inspiratory time and depth of inspiration ◗ IPAP & EPAP can be increased by increments of 2 ◗ BiPAP = CPAP + Pressure support during inspiration
  • 16.
    1.Cardiogenic pulmonary edema, exacerbation of COPD , Post-op respiratory failure. 2.Neuromuscular disease with respiratory muscle weakness, OSA. 3.Terminallyill patients compromised patients. 4 Weaning mode. & Immuno
  • 17.
    Advantages: 1 Complications ofintubation –avoided 2 Allows speech ,feeding Disadvantages: 1.Respiratory drive and intact upper airway 2.Cannot protect airway and does not provide full 100% ventillatory support 3. Claustrofobia & uncomfortable for patients
  • 18.
    ◗ Improvement in: 1.Respiratory rate and heart rate 2. Dyspnea 3. Oxygen requirement 4. Hypercarbia
  • 19.
     Provides allthe energy for Alveolar Ventilation  Every breath is fully supported by the ventilator  In classic control modes, patients are unable to breathe except at the controlled set rate  In newer control modes, machines may act in assist-control, with a minimum set rate and all triggered breaths above that rate are also fully supported.  Ensures that patient is not required to do any Work Of Breathing
  • 20.
    When to Consider: ◗Spontaneously breathing patient. ◗ Comfortably provide a portion of their required minute volume ◗Useful for weaning patients from MV support When not to consider: ◗ Should be avoided in case of patients with ventilatory muscle fatigue
  • 21.
    PRESSURE VOLUME Tidal VolumeVariable Constant Peak Ins Pressure Constant Variable Dys-synchrony Less More likely Barotrauma Less More likely Flow Pattern Decreasing Preset
  • 22.
    ◗ Balance CO2removal v/s lung protection ◗ If CO2 clearance more important than lung protection, use volume. ◗ If lung protection is more important than CO2 removal use PRESSURE ◗ If patient triggered ventilation, synchrony may be enhanced with PRESSURE
  • 23.
    ◗ The ventilatordelivers a preset TV at a specific R/R and inspiratory flow rate. ◗ It is irrespective of patients’ respiratory efforts. ◗ In between the ventilator delivered breaths the inspiratory valve is closed so patient doesn’t take additional breaths. ◗ PIP developed depends on lung compliance and respiratory passage resistance.
  • 25.
    ◗ Ventilator givespressure limited, time cycled breaths thus preset inspiratory pressure is maintained. ◗ Decelerating flow pattern. ◗ Peak airway/alveolar pressure is controlled but TV, minute volume & alveolar volume depends on lung compliance, airway resistance, R/R & I:E ratio.
  • 27.
    ◗ Ventilator assistspatient’s initiated breath, but if not triggered, it will deliver preset TV at a preset respiratory rate (control).  patient (control) ◗ If R/R triggered (assist) or time triggered > preset rate, ventilator will assist, otherwise it will control the ventilation.
  • 29.
    ◗ Ventilator deliverseither assisted breaths at the beginning of a spontaneous breath or time triggered mandatory breaths. ◗ Synchronization window- time interval just prior to time triggering. ◗ Breath stacking is avoided as mandatory breaths are synchronized with spontaneous breaths. ◗ In between mandatory breaths patient is allowed to take spontaneous breath at any TV.
  • 31.
    ◗ Patient isspontaneously breathing ◗ The vent augments the patient’s respiratory effort with a “pressure support” ◗ Tidal Volume is determined by patient’s effort and respiratory system compliance ◗ Can set a FiO2 PEEP and PS above PEEP ◦ Can not set respiratory rate except back-up apnea rate.
  • 32.
    ◗ FiO2 ◗ TidalVolume /Pressure ◗ Respiratory Rate ◗ PEEP ◗ Flow Rate ◗ I:E Ratio ◗ Trigger
  • 33.
    Start with FiO2=1.0 and titrate to SpO2 >=94% ABG after 20-30min Goal –PaO2 between 60 –100 mmHg If FiO2 requirement is>0.5 , increase PEEP FiO2 =1.0, before & after suction, during bronchoscopy, & any other risky procedure
  • 34.
    ◗ The tidalvolume is the amount of air delivered with each breath. ◗ Initial tidal volumes should be 8-10ml/kg, depending on patient’s body habitus. ◗ If patient is in ARDS consider tidal volumes between 4 – 6 ml/kg with increase in PEEP ◗ In Pressure-Targeted modes you’ll set the Pressure High (PH) according to the delivered tidal volume
  • 35.
    ◗ Males: IBW= 50 kg + 2.3 kg for each inch over 5 feet. ◗ Females: IBW = 45.5 kg + 2.3 kg for each inch over 5 feet.
  • 36.
     An optimalmethod for setting the respiratory rate has not been established. ◗ 12 - 15/Min – Adult 20+_ 3 - Child 30- 40 - New born On somemachines you set the Inspiratory Time (Ti) and Expiratory Time (Te)
  • 37.
    ◗ Increase RR– Hypoxia Hypercapnoea / Resp. Acidosis ◗ Decrease RR- Hypocapnoea Resp. Alkalosis Asthma / COPD
  • 38.
    •Minute Ventilation (L/min)= RR (b/min) x Tidal Volume (liters) •If you decrease one or both the MV will decrease resulting inHypercapnia •Tolerated in status asthmaticus and ARDS/ALI – Called “permissive hypercapnea”
  • 39.
    ◗ A typicalinitial PEEP applied is 5 cmH2O. ◗ Adjust up by increments of 2 for marked hypoxia ◗ However, up to 20 cm H2O used in ARDS ◗ PEEP increases intra thoracic pressure and can thus decrease venous return and thus Blood Pressure
  • 40.
     Improves oxygenation RecruitsLung in ARDS Prevents collapse of alveoli Diminishes the work of breathing
  • 41.
    ◗ Peak flowrates of 60 L per minute ◗ Higher rates are frequently necessary in Asthma or those with air hunger ◗ An insufficient peak flow rate is characterized by dysnoea, spuriously low peak inspiratory pressures, and scalloping of the inspiratory pressure tracing ◗ Pressure-Targeted modes allow patient to dictate the flow rate that they want
  • 42.
    ◗ During spontaneousbreathing, the normal I:E ratio is 1:2. ◗ If exhalation time is too short “breath stacking” occurs resulting in an increase in end-expiratory pressure also called auto-PEEP. ◗ Asthma/COPD 1:3, 1:4, … ◗ Severe hypoxia ARDS 1:1, 2:1,
  • 43.
    ◗ Most frequentlyused to obtain an estimate of Plateau pressure and static compliance ◗ Patient should not be actively breathing ◗ When used with each breath, improves distribution of air, V/Q ratio.
  • 44.
    ◗ Pressure triggering -1to-2cm H2O Ventilator-delivered breath is initiated if the demand valve senses a negative airway pressuredeflection greater than thetrigger sensitivity. ◗ Flow triggering 1 to 3 L/ min (preferred) Continuous flow of gas through the ventilator circuit is monitored. A ventilator delivered breath is initiated when the return flow is less than the delivered flow
  • 45.
    •different medications forsedation. •Opiates (morphine, fentanyl) Benzodiazepines (Midazolam) • Propofol • Less is sometime more
  • 46.
    • Paralysis withoutsedation = Torture Atracurium,Vecuronium can be used •All one needs in this situation is chemical weakening…
  • 47.
    • Low pressure, •High pressure limit and alarm • Volume alarm(low TV, high and low minute ventilation) • High respiratory rate alarm • Apnea alarm and apnea values • High/low temperature alarm • I:E ratio limit and alarm
  • 48.
    Complications of positive pressureventilation Increase in positive airway pressure ● High intrathorasic pressure ● this pressure transmitted to airway,alveoli,as as mediastinum and great vessels ● Compression of great vessels ●Decreased venous return Decreased strock volume and D c ease oxy n elivecrayrdiac oHuytppoutetnsion ec eased r na lood fl decreased GFR 29 decreased urine output51
  • 49.
    Weaning The process ofwithdrawing mechanical ventilatory support and transferring the work of breathing from the ventilator to patient. 5 2
  • 50.
     Improvement of thecause of respiratory failure  Absence of major system dysfunction  Appropriate level of oxygenation Adequate ventilatory status  Intact airway protective mechanism (needed for extubation) 53
  • 51.
    Rapid Shallow BreathingIndex • Failure of weaning may be related to the development of a spontaneous breathing pattern that is rapid (high frequency) and shallow (low tidal volume). • The rapid shallow breathing index (RSBI) or f/VT index has been used to evaluate the effectively of the spontaneous breathing pattern. • Favourable RSBI is < 105 54
  • 52.
    ◗ No one ormethod of weaning has been definitely found to be superior; ◗ Spontaneous Breathing Trial ◗ Pressure Support Ventilation ◗ Other Modes of Partial Ventilatory Support     SIMV Volume support (VS) and volume-assured pressure support (VAPS) Mandatory minute ventilation (MMV) Airway pressure-release ventilation (APRV) 55
  • 53.
    PROCEDU Steps RE PSV 1.PSVmay be used in conjunction with spontaneous breathing or SIMV mode; 2.Start PSV at a level of 5 to 15 cm H2O (up to 40 cm H2O) to augment spontaneous VT until a desired VT (10 to 15 mL/kg) or spontaneous frequency (<25/min) is reached; 3.Decrease pressure support (PS) level by 3 to 6 cm H2O intervals until a level of close to 5 cm H2O is reached; 4.If patient tolerates step (3), consider extubation when blood gases and vital signs are satisfactory. 56
  • 54.
    What after weaning • Oxygentherapy • Close monitoring: ABGs evaluation, Pulse oximetry • Bronchodilator therapy • Chest physiotherapy • Adequate nutrition, hydration, and humidification • Incentive spirometry 57
  • 55.
  • 56.
    59 • The ETTmust be repositioned and re-secured at least once a shift to prevent tissue breakdown • Mouth care needs to be performed routinely • Cuff pressure needs to be assessed once a shift • Sometimes a higher pressure is needed to seal (ETT is too small, anatomical differences) • Check for proper inflation, determine the location of the leak, assess the integrity of the pilot line • Suctioning Management of the tube
  • 57.
    Evaluating for Leaks •Every ventilator check must include assessing the circuit integrity • PIP and Vt measurements are lower than previous measurements • Start at the patient connection and work back to the ventilator • May need to disconnect the patient and provide manual ventilation while testing the circuit 60
  • 58.
    ◗ Check plateaupressures by allowing an inspiratory pause (this gives you the pressure in the lung itself without the addition of resistance) pressures are low then you have an obstruction  ◗ If both peak pressures and plateau pressures are high then you have a lung compliance issue
  • 60.
    ◗ High peakpressure differential: High Peak Pressures Low Plateau Pressures High Peak Pressures High Plateau Pressures Mucus Plug Bronchospasm ET tube blockage Biting ARDS Pulmonary Edema Pneumothorax ET tube migration to a single bronchus Effusion
  • 61.
    ◗ Increase inpatient agitation and dis- synchrony on the ventilator: ◦ Could be secondary to overall discomfort • Increase sedation ◦ Could be secondary to feelings of air hunger • Options include increasing tidal volume, increasing flow rate, adjusting I:E ratio, increasing sedation
  • 62.
    • Early useof NPPV •Prepare and expect hypotension during intubation – IVF bolus •Mechanical Ventilation Strategy – Permissive Hypercapnia • Ventilator maneuvers that prolong I:E – Low tidal volumes, low respiratory rates, square wave forms, high flow rates.
  • 63.
    • Tidal Volumes:6-7 ml/kg (IBW) • Respiratory Rate: 8-10 bpm • Flow Rate: 80-100 L/min • Square Wave forms • SEDATION: propofol,fentanyl • Last resort: chemical weakening • Expect high peak pressures
  • 64.
    ◗ Lung ProtectiveStrategy ◗ Low-Tidal Volumes ◗ Start at 6 mL/kg IBW ◗ Goal of 4-6 mL/kg IBW ◗ Low Plateau Pressures – Less than 30 ◗ High PEEP ◗ Permissive hypercapnia