This document provides an overview of using KNIME and Python for artificial intelligence (AI) and machine learning (ML) model building. It discusses that KNIME is a user-friendly platform for data science workflows without coding, while Python is widely used for AI/ML due to its many libraries and being platform independent. The document then provides step-by-step instructions on building basic ML models in KNIME, including data import, cleaning, visualization, linear regression training and prediction, and model evaluation. It concludes that both KNIME and Python are good options, with KNIME being more accessible and Python having more extensive library support and community.