Calamine lotion

Calamine lotion

• 1.
  Calamine Lotion Dr. RahulKumar Bhati
• 2.
  Aim: To prepareand dispense 20 ml of calamine lotion. Requirements: • Apparatus: Dispensing balance and fractional weights, mortar and pestle, measuring cylinder, coloured dispensing bottle with stopper, scissor, spatula, pipette, gum, white paper etc.
• 3.
  • Ingredients &calculation: For 100 ml For 20 ml Calamine 15 g 3 g ZnO 5 g 1 g Bentonite 3 g 0.6 g Glycerine 5 ml 1 ml Aqua ad. 100 ml 20 ml
• 4.
  Procedure: The balance waschecked, appropriate corrections made Required amounts of calamine, ZnO and bentonite were weighed, placed in a mortar, The mixture was grinded to make them fine paticles 1 ml of glycerine and 3-5 ml of water was added; and a fine paste was made out of them Transferred to measuring cylinder, mortar was rinsed with water and rinsed water was transferred to the cylinder volume was made upto 20 ml by adding water to the cylinder Transferred to dispensing bottle bottle was labeled and dispensed
• 5.
  Label: The Lotion Name: Mr.Raman Age: 24 years Sex : Male Address: Safdarjung Enclv, New Delhi-29 Date: 29/09/2009 Direction:- Apply on the affected area 2-3 times daily Prepared at Pharmacy Lab VMMC Dispensed by Name Regd. No. FOR EXTERNAL USE ONLY SHAKE WELL BEFORE USE
• 6.
  Prescription for 20ml of Calamine Lotion For Name: Mr. Raman Age: 25 years Sex: Male Address: Safdarjung Encl., New Delhi Dr.Rahul Bhati; (MD) Address: 615, VMMC, New Delhi-29 Phone Number: 99999999 R Calamine 15 g ZnO 5 g Bentonite 3 g Glycerine 5 ml Aqua ad. 100 ml Mix and make lotion; send such 20 ml. To be applied 2-3 times daily on the affected area. Signature of Dr KC Sahoo Regd. No: 123/07 Date: 28/09/2017 ∕
• 7.
  Notes: • Indications: – Eczema –Impetigo – Sun burn – Dermatitis – Itching – Varicose ulcers – Psoriasis
• 8.
  • Calamine: – ZnO(98%) + Fe2O3 (2%) – Fe2O3 imparts color and it is irritant. So applied to only over intact skin, not on open wound • ZnO: – Antiseptic, astringent. – Protective and soothing agent. – Substances that precipitate proteins but do not penetrate cells, thus affecting superficial layer only.
• 9.
  • Bentonite: – Hydratedaluminium silicate. – When water is added it, swells up to give a gel- like but non-viscous consistency. – It acts as suspending agent and reduce viscosity. – It helps to make the lotion uniform.
• 10.
  • Glycerine: – Hygroscopicin nature. – Prevents drying of lotion, so lotion remains at the site of application for a longer time. – Also antiseptic and emollient (oily substance). Sooths and softens the skin. – Forms an occlusive film over skin and prevent evaporation, thus restores elasticity of cracked and dry skin.
• 11.
  • Precautions: – Shouldnot be applied on wounds or injured areas because it precipitates proteins and form a layer which prevents healing. • Lactocalamine: – Market preparation which contains casein and phenol besides the normal constituents. – Casein acts as soothing agent, while phenol acts as a preservative and antiseptic.